Tuesday, July 31, 2018 by Zoey Sky
Atypical lipomatous tumors are slow-growing and cancerous soft tissue tumors. They usually develop in the retroperitoneum/abdominal region, the limbs, the chest region, or the spermatic cord of the testes.
Why these tumors develop remains unknown, but experts believe that they are linked to some genetic mutations.
According to the World Health Organization (WHO), there are four types of atypical lipomatous tumors:
- Inflammatory atypical lipomatous tumors – These tumors have prominent inflammatory cells.
- Lipoma-like atypical lipomatous tumors – While these tumors have very good prognosis following complete removal, they can be difficult to diagnose because they look like benign lipomas.
- Sclerosing atypical lipomatous tumors – These tumors often form in the retroperitoneum or the paratesticular region.
- Spindle cell atypical lipomatous tumors – These tumors can develop in the retroperitoneum, the spermatic cord, and in the subcutaneous tissue.
Atypical lipomatous tumors are also called well-differentiated liposarcomas.
Known symptoms of atypical lipomatous tumors
The symptoms of atypical lipomatous tumors may vary depending on where they form.
The condition can include symptoms like:
- A painless tumor that forms on the thigh or spermatic cord.
- Slow-growing and painless tumors.
- Thigh tumors that can cause leg pain and restricted movement or walking difficulties.
- Tumors in the chest cavity that cause breathing difficulties.
- Tumors in the retroperitoneal space may not cause any symptoms until it grows large enough to compresses the adjacent organs in the abdomen. This is why some retroperitoneal tumors remain undetected in the early development stage.
- Tumors that form on the retroperitoneum, extremities (e.g., arms and leg, especially the thigh), the spermatic cord of the testes, and mediastinum/between the lungs in the chest.
Body systems harmed by atypical lipomatous tumors
Atypical lipomatous tumors may cause the following complications:
- Damage to the blood vessels, muscles, and vital nerves – This can occur during surgery to remove tumors.
- Abdominal pain, frequent urination, kidney failure (because of compression of the kidney), and weight loss – These complications may occur due to large tumors in the retroperitoneal cavity.
- Tumor recurrence – Even after surgery tumors have at least a 30 percent chance of recurring.
- Varicose veins – This can occur due to leg tumors.
Food items or nutrients that may prevent atypical lipomatous tumors
The following foods or nutrients can help prevent atypical lipomatous tumors or address its symptoms:
- Berries – Berries have cancer-fighting phytonutrients, but black raspberries are full of phytochemicals called anthocyanins that can slow down the growth of premalignant cells.
- Broccoli – Like other cruciferous vegetables, broccoli has cancer-fighting properties. It also contains sulforaphane, a powerful, potent compound that boosts the body’s protective enzymes and eliminates cancer-causing chemicals
- Garlic – Garlic contains phytochemicals that can stop the formation of nitrosamines, the carcinogens that form in the stomach when you consume common food preservatives called nitrates.
- Tomatoes – Tomatoes have lycopene, a carotenoid that can help prevent stop endometrial cancer cell growth.
- Walnuts – Walnuts have phytosterols, the cholesterol-like molecules in plants, that can block estrogen receptors in breast cancer cells. Phytosterols can help slow the growth of these cells.
Treatments, management plans for atypical lipomatous tumors
Since atypical lipomatous tumors don’t metastasize, the prognosis for patients is positive following early detection and the complete removal of the tumor.
Treatment options for atypical lipomatous tumors include:
- Chemotherapy and radiation therapy – May be recommended depending on the specific case.
- Complete surgical excision with clear margins – This is an effective treatment option.
- Limb amputation – May be recommended in rare cases involving limb tumors.
Where to learn more
Atypical lipomatous tumors are slow-growing and cancerous soft tissue tumors. They usually develop in the retroperitoneum/abdominal region, the limbs, the chest region, and the spermatic cord of the testes.
The condition can include symptoms like slow-growing and painless tumors, leg pain and restricted movement or walking difficulties, or breathing difficulties.
Atypical lipomatous tumors may cause complications like damage to the blood vessels, muscles, and vital nerves; abdominal pain, frequent urination, kidney failure (because of compression of the kidney), and weight loss; tumor recurrence, and varicose veins.
Berries, broccoli, garlic, tomatoes, and walnuts can help prevent atypical lipomatous tumors or address its symptoms.
Treatment options for atypical lipomatous tumors include chemotherapy and radiation therapy, complete surgical excision with clear margins, or limb amputation.