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Lotronex – uses, health risks, and side effects at

Wednesday, September 05, 2018 by

Lotronex (Generic name: alosetron) prevents the action of serotonin in the intestines. This slows bowel movements through the intestines. Lotronex is used for the treatment of severe, chronic irritable bowel syndrome (IBS) in women who have had diarrhea as the primary symptom for a minimum six months. Alosetron belongs to a class of medications called 5-HT3 receptor antagonists.

This drug should be only used by women who have tried other IBS treatments but failed. It has not been shown to be effective in men with IBS. It is an oral tablet usually taken twice a day with or without food. Lotronex can interact with other drugs, and some drugs should not be used together with it, such as prescription, and over-the-counter medicines, vitamins, and herbal products.

Known side effects of Lotronex

The common side effects of Lotronex include the following:

  • Bloating
  • Burping with heartburn
  • Constipation
  • Gas
  • Hemorrhoids
  • Nausea
  • Skin rash
  • Stomach upset or discomfort

Lotronex can also cause an allergic reaction, with signs such as difficulty breathing, hives, or swelling of the face, lips, tongue, or throat. It can also cause serious or fatal side effects on the stomach and intestines, such as severe constipation or ischemic colitis.

Body systems that may be harmed by Lotronex

The body systems that may be harmed by Lotronex include the gastrointestinal, respiratory, genitourinary, hepatic, dermatologic, nervous, musculoskeletal, cardiovascular, metabolic, immune, ocular, endocrine, and hematologic systems.

Food items or nutrients that may prevent side effects of Lotronex

The following food items may prevent and treat nausea, one of the common side effects of Lotronex:

  • Applesauce
  • Bananas
  • Broths
  • Cold foods
  • Crackers
  • Ginger
  • Herbal teas like peppermint and chamomile
  • Noodles
  • Potatoes
  • Protein-rich meals
  • Rice
  • Water

Treatments, management plans for the side effects of Lotronex

The following are some natural treatments for several side effects of Lotronex:

  • Bloating: Bloating can be treated with herbs and spices, such as ginger, chamomile, dill, fennel, basil, caraway, cumin, parsley, peppermint, and spearmint. It can also be treated with probiotic foods, such as yogurt, kefir, tempeh, kimchi, and sauerkraut.
  • Constipation: Constipation can be treated naturally by drinking more water, eating more fiber, exercising more, drinking coffee, taking an herbal laxative called senna, eating probiotic foods, eating shirataki noodles, eating prebiotic foods, eating prunes or drinking prune juice, and avoiding dairy.
  • Nausea: Nausea can be treated naturally by using ginger in cooking or drinking it in tea, drinking peppermint tea, trying acupuncture and acupressure, and trying aromatherapy.

Where to learn more


Lotronex is a drug used to treat severe, chronic irritable bowel syndrome (IBS) in women with diarrhea as the primary symptom.

Lotronex commonly causes bloating, burping with heartburn, constipation, gas, hemorrhoids, nausea, skin rash, and stomach discomfort.

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