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AmBisome – uses, health risks, and side effects at

Tuesday, August 07, 2018 by

AmBisome, or amphotericin B liposomal, is an antifungal medication that is used to prevent infections caused by fungus.

The drug is given to patients who have severe and life-threatening fungal infections such as leishmaniasis, along with a specific kind of meningitis in individuals infected with human immunodeficiency virus (HIV).

Known health risks or side effects of AmBisome

AmBisome may cause common side effects such as:

  • Appetite loss, an upset stomach
  • Bruising, pain, or swelling at the site of injection
  • Diarrhea, nausea, stomach pain, and vomiting
  • Flushing (redness, a tingly feeling, or warmth in the affected area)
  • A headache, ringing in the ears
  • Joint or muscle pain
  • Weight loss

You may require immediate medical attention if you experience severe side effects such as:

  • Bloody stools
  • A build-up of fluid in the lungs – This can cause anxiety, chest pain, cough with foamy mucus, a fast or uneven heart rate, gasping for breath, or sweating.
  • Convulsions/seizure
  • Easy bruising, pale skin
  • Jaundice/the yellowing of the skin or eyes
  • Kidney problems – This can include signs like feeling tired or short of breath, little or no urination, pain or difficulty when urinating, and swelling in the ankles or feet.
  • A light-headed feeling, like you’re going to pass out
  • Low potassium – May include signs like confusion, extreme thirst, increased urination, leg discomfort, a limp feeling or muscle weakness, or an uneven heart rate.
  • A new infection – Can include signs like chills, fever, flu symptoms, mouth and throat ulcers, and rapid and shallow breathing.

List of organs that might be affected by AmBisome

An overdose of AmBisome may cause an allergic reaction. Signs include difficulty breathing; hives; swelling of your face, lips, tongue, or throat; or wheezing.

An overdose of the drug can also result in death.

Food items or nutrients that have similar effects to AmBisome

If you have leishmaniasis following a healing diet can help. According to the World Health Organization (WHO), leishmaniasis can progress to visceral leishmaniasis due to malnutrition. A diet full of iron, protein, vitamin A, and zinc can help lower your risk of developing visceral leishmaniasis. Consume foods like garlic, which have antibacterial or antimicrobial properties that can help your body fight off the disease.

Mayan remedies used to treat leishmaniasis included Pentalinon andrieuxii, a medicinal Mexican plant. According to a study, sterol pentalinonsterol in an intravenous treatment can also be used to treat visceral leishmaniasis and that it helped reduce parasites in the liver and spleen.

Another ancient remedy for multiple strains was the ground-up and dried leaves of the Urechites andrieuxii. The leaves were rubbed directly on the lesion. A separate study showed that methanol extracts from both the leaves and roots of the plant had antileishmanial activity against the L. braziliensis, L. amazonensis, and L. donovani parasite species.

Treatment and management options for the side effects of AmBisome

The following treatments and management options can help prevent the side effects associated with AmBisome:

  • Almonds – If you have a headache, eat some almonds. Almonds are a natural remedy for everyday tension-type headaches. Almonds acts as a pain reliever since it contains salicin, an agent used in over-the-counter painkillers. Eat a handful or two of almonds to ease a headache. (Do take note that almonds can trigger migraines in some people.)
  • Aloe vera – Aloe vera has antibacterial, antifungal, anti-inflammatory, and emollient properties. It can help treat rashes and soothe irritated skin. Aloe vera can help relieve itching and reduce redness. Apply fresh aloe vera gel from an aloe leaf on the affected area. Leave it on for about 20 minutes then rinse it off. Apply the gel thrice a day until the rash clears.
  • Olive oil – Extra-virgin olive oil is a natural skin moisturizer, and it can facilitate healing and promote skin renewal. It’s rich in antioxidants and vitamin E, and olive oil can help soothe irritated skin and minimize itching. Apply some olive oil on the affected area. You can also combine equal parts of olive oil and honey on a rash several times a day until it’s fully healed.

Where to learn more


AmBisome, or amphotericin B liposomal, is an antifungal medication that is used to prevent infections caused by fungus.

AmBisome may cause common side effects such as diarrhea, nausea, stomach pain, and vomiting.

An overdose of AmBisome may cause an allergic reaction or even death.

A healing diet, Pentalinon andrieuxii, and Urechites andrieuxii have similar effects to AmBisome.

Almonds, aloe vera, and olive oil can help prevent the side effects associated with AmBisome.

Sources include:


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