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"The dual reuptake inhibitors venlafaxine and duloxetine do seem to have a slight advantage in terms of efficacy over SSRIs and the other antidepressants like the tricyclics, but at least in the case of venlafaxine the suicide risk may negate the added efficacy. For severe depression, especially for those who have no response to an SSRI, some of the tricyclics, like imipramine or clomipramine, may work better and are worth a try. For bipolar (manic-depressive) disorder, lithium is useful for preventing a return of manic episodes." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"There are a lot of data showing that people who sleep poorly are more likely to relapse [with depression] and that suicide risk is higher," Sussman said. Sleep problems also often require additional medication: 22 percent to 34 percent of patients taking SSRIs are also prescribed sedatives or hypnotics. There can also be bizarre sexual side effects—such as "yawning-excitement syndrome," in which patients experience sexual arousal when they yawn, even progressing to orgasm. "This is probably underreported," Dr. Sussman said." - Charles Barber, Comfortably Numb: How Psychiatry Is Medicating a Nation (Get the book.) "Since even one previous attempt multiplies suicide risk by 38 to 40 times, and suicide is the fourth leading cause of death for adults, a proven way to prevent repeat attempts has important public health implications," said the Director of the National Institute of Mental Health, Thomas Insel.18 CBT has some highly practical applications. Researchers in the physiotherapy department at King's College, London, administered a cognitive-behavioral pain management program for patients experiencing chronic pain after cancer treatments such as surgery, radiotherapy, and chemotherapy." - Charles Barber, Comfortably Numb: How Psychiatry Is Medicating a Nation (Get the book.)

"The FDA had not yet forced the antidepressant manufacturers to add the warning about "Clinical Worsening and Suicide Risk" described in chapter 5.30 Elliot was already suffering from several of the symptoms that Paxil causes or exacerbates—anxiety, agitation, insomnia, irritability, hostility, aggressiveness, and impulsivity—so that Paxil became a prescription for disaster." - Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.) "In 2004 to 2005, the FDA had previously concluded that these drugs do indeed cause a suicide risk in children. In May 2006, before the last of my three reports was published, GSK published to the world the results of its new FDA-mandated reevaluation of its clinical trials. The reevaluation showed that Paxil increased suicidal behavior in adults. This was nearly five years after I had tried and failed to get the company to allow me to release my findings demonstrating that Paxil increased suicidal behavior." - Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.) "APPLYING THE SUICIDE WARNING TO ADULTS TAKING ANTIDEPRESSANTS BENEATH THE BLACK BOX, the FDA mandated another new section entitled, "warnings: Clinical Worsening and suicide risk," that applies to children and to adults. It observes, "There has been a long-standing concern that antidepressants may have a role in inducing worsening of depression and the emergence of suicidality in certain patients." - Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.) "This critical new addition to all antidepressant labels is found in the section entitled, "warnings: Clinical Worsening and suicide risk." The label warning specifically refers not only to children but also to adults. It warns about "anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness), hypo-mania, and mania." This is medication madness! Except for suicidality, which is covered elsewhere in the label, this part of the warning applies to and describes one or another aspect of all the cases in this book." - Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"The one advantage of the new drugs is that they cause about 12 percent fewer side effects, but that hardly justifies using them routinely for all depressed patients, considering the possibility of increased suicide risk and the increased cost. With only selective reporting of commercially sponsored clinical trials, doctors reading their journals are led to believe that newer drugs are more effective and less dangerous than older drugs, even when the actual scientific evidence points in the other direction." - John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"In May 2004, after an indepth investigation, the United States Preventive Services Task Force issued a report with findings that: (1) There is no evidence that screening for suicide risk reduces suicide attempts or mortality; (2) There is limited evidence on the accuracy of screening tools to identify suicide risk; and (3) There is insufficient evidence that treatment of those at high risk reduces suicide attempts or mortality. (http://www.sierratimes.com/06/07/22/71 158 154 172 87990." - Dr David W Tanton, Ph.D., Antidepressants, Antipsychotics, And Stimulants - Dangerous Drugs on Trial (Get the book.)

"Internal company documents that became public included a memo to company sales reps that instructed them specifically not to discuss the potential suicide risk with physicians. Other company research suggested that as many as one in four patients on Paxil suffer withdrawal symptoms if they abruptly stop taking the drug. As David Healy, a British psychiatrist who helped spark recent investigations into the potential dangers of SSRIs, puts it, "If you've got a very severe problem, and I treat you with a drug like Paxil, I may save your life, I may save your marriage, I may save your career." - Shannon Brownlee, Overtreated: Why Too Much Medicine Is Making Us Sicker and Poorer (Get the book.)

"And indeed, the devastating so-called 'withdrawal syndrome' associated with some of the SSRI antidepressants, coupled with an increased suicide risk particularly among young people, again in only some of the drugs are why the pharmaceutical industry has been getting a bad press recently. More money, fewer drugs But it is the dynamics of the markets themselves that expose the public to greater than necessary risk. Intense pressure on companies to increase their share of the big markets has, over the years, developed a momentum of its own, compelling companies to merge if they want to survive." - Jacky Law, Big Pharma: Exposing the Global Healthcare Agenda (Get the book.)

"Internal company documents that became public included a memo to company sales reps that instructed them specifically not to discuss the potential suicide risk with physicians. Other company research suggested that as many as one in four patients on Paxil suffer withdrawal symptoms if they abruptly stop taking the drug. As David Healy, a British psychiatrist who helped spark recent investigations into the potential dangers of SSRIs, puts it, "If you've got a very severe problem, and I treat you with a drug like Paxil, I may save your life, I may save your marriage, I may save your career." - Shannon Brownlee, Overtreated: Why Too Much Medicine Is Making Us Sicker and Poorer (Get the book.)

"As a result, the USPSFT could not determine the balance of benefits and harms of screening for suicide risk in the primary care setting. "8 So, according to the USPSFT, there is insufficient evidence to support the claim that screening reduces the risk of suicide attempts, and it further states that there is insufficient evidence that "treatment" reduces suicide attempts. This is important information when one considers the other goal associated with the nationwide mental health plan." - Kelly Patricia O'Meara, Psyched Out: How Psychiatry Sells Mental Illness and Pushes Pills That Kill (Get the book.) "Screening for Suicide Risk: Recommendation Statement; U.S. Preventive Services Task Force, May 2004. 9 Laurie Flynn, Community Voices "Before Their Time: Preventing Teen Suicide," September 2005. 10 Michael F. Hogan, Ph.D., Chairman, President's New Freedom Commission on Mental Health, Summary July 22, 2003, Pg-68. " Laurie Flynn, Director, TeenScreen, Columbia University, U.S. Senate Committee on Health, Education, Labor, & Pensions, Congressional Testimony, "Suicide Prevention and Youth: Saving Lives," March 2, 2004 12 Ibid." - Kelly Patricia O'Meara, Psyched Out: How Psychiatry Sells Mental Illness and Pushes Pills That Kill (Get the book.) "Post front-page article by Ron Stein and Marc Kaufman headlined "Depression Drugs Safe, Beneficial, Studies Say: suicide risk Rejected, But Critics Question Validity of Findings, " covers in some detail the results of two taxpayer-funded studies that report to negate the FDA's earlier conclusions about the potentially deadly risks associated with antidepressant use, which moved the FDA to request of the pharmaceutical companies to place "black box" warnings on the psychiatric mind-altering drugs." - Kelly Patricia O'Meara, Psyched Out: How Psychiatry Sells Mental Illness and Pushes Pills That Kill (Get the book.) "Ron Stein and Marc Kaufman, "Depression Drugs Safe, Beneficial, Studies Say: suicide risk Rejected, But Critics Question Validity of Findings," The Washington Post, January 1, 2006. 13 "FDA Stance on Antidepressant Warnings Unchanged By NIMH Suicide Findings," Pink Sheet, January 9, 2006. Volume 68, Number 002, pg-16. 14 "Researchers Link A Protein to Depression," The Washington Post, January 6, 2006. 15 Ibid. 16 Keith Hoeller, "War of Two Religious Worldviews," The Washington Times, July 7, 2005. 17 Chuck Conconi, "Stop the Presses!" - Kelly Patricia O'Meara, Psyched Out: How Psychiatry Sells Mental Illness and Pushes Pills That Kill (Get the book.)

"Emotional Well-Beim Antidepressants Do Raise Kids'Suicide Risk: Study here is new evidence that 'a. the use of common antics depressants increases the mm risk of suicide in children and adolescents. Though much of the previous research had focused on users' suicidal thoughts and actions, this study "focused on things that are at the far more severe end of the spectrum— kids coming into the emergency room following suicide attempts and those who actually die," says Dr." - Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.)

"Speaking to an FDA advisory panel convened in 2004 to decide whether to place a prominent suicide risk warning on antidepressants, Healy, who still believes in the therapeutic value of well-monitored SSRIs, delivered a damning set of data. "There have been 677 trials involving SSRIs," he said, "and having helped review all of these, I can let you know that roughly only a quarter of the suicidal acts that have happened in these trials have been reported in the scientific articles that have come out of those trials." There were all kinds of duplicity and institutional leniency at work as well." - Greg Critser, Generation Rx: How Prescription Drugs are Altering American Lives, Minds, and Bodies (Get the book.) "But the FDA, already getting an earful about suicide risk and Prozac, was worried about the "public relations" effect of such figures, and wrote SmithKline, telling the company to resubmit its data. As a number of court cases now reveal, SmithKline reran the numbers, giving the drug a more benign profile. Paxil sailed to approval. As Healy noted, "They were only doing what Lilly and Pfizer had already done." - Greg Critser, Generation Rx: How Prescription Drugs are Altering American Lives, Minds, and Bodies (Get the book.)

"He was aware of the research indicating an increase in suicide risk for those on SSRI antidepressants. He was also aware that Effexor's claim to be superior to other antidepressants was false. But instead of notifying the writing agency that he did not want his name on ghosted articles, he decided to test the system. He accepted the article, inserted what he termed "two viruses," and then returned the article without making any other changes. The first "virus" was a statement that Effexor was not superior to another drug, Remeron." - Dr. Timothy Scott, America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived (Get the book.) "They simply reworked it and published it—with the Remeron and the suicide risk comments removed— under the names of some new "authors."7 This is not a rare event. There are numerous ghostwriting agencies composing and publishing articles in medical journals. As a result of a lawsuit against Pfizer, documents were made public which revealed they had used a New York ghostwriting agency to produce nearly 90 articles for their antidepressant Zoloft." - Dr. Timothy Scott, America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived (Get the book.)

"Clinical application of low serum cholesterol as an indicator for suicide risk in major depression. J Affect Disord. 2004 Aug;81(2): 161-6. Statins are handled by the body as poisons. They may have their toxicity increased significantly by interaction with other medication or by an individual's unique detoxification capacity. They may interact adversely with several hundred common drugs, making their use difficult to monitor for safety. 71. Andreou ER, Ledger S. Potential drug interaction between simvastatin and danazol causing rhabdomyolysis. Can J Clin Pharmacol. 2003 Winter;10(4): 172-4." - Byron J. Richards, Fight for Your Health: Exposing the FDA's Betrayal of America (Get the book.)

"Most Americans are very aware of the much reported FDA warnings concerning suicide risk for children on antidepressants. Based on 24 trials the FDA stated that they believed the risk was twice as great for children on antidepressants as compared with those on placebo.18 It was unfortunate that the FDA did not issue a similar warning for adult use as the German drug regulators felt would be necessary if Prozac were ever to be approved in Germany. That was 1985, two years before Prozac began to be prescribed in our nation." - Dr. Timothy Scott, America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived (Get the book.)

"It will be interesting to see whether the current concerns with suicide risk among adolescents taking SSRIs or the recent reports of increased cardiac risks from stimulants (Nissan, 2006) will have an impact on the number of individuals who receive treatment with these drugs. Finally, the National Comorbidity Study example illustrates how psychiatric research itself can potentially medicalize more of life's problems and overstate the existence of untreated psychiatric "pathology." - Peter Conrad, The Medicalization of Society: On the Transformation of Human Conditions into Treatable Disorders (Get the book.)

"S, Food and Drug Administration Prozac doubles suicide risk. British Medical Journal HRT increases stroke risk by 30%. British Medical Journal Heart drug causes kidney failure. University of Michigan Viagra causes blindness in some users. University of Minnesota Medical School Antipsychotic drugs increase mortality rate in elderly patients. FDA Acetaminophen linked to asthma and pulmonary disease. Third National Health and Nutrition Survey III Asthma drugs make symptoms worse. FDA Statin drugs increase risk of stroke for severely ill diabetics." - Mike Adams, Natural Health Solutions (Get the book.)

"Many studies shows that statins disturb the brain and nerves, inducing neuropathy, depression, memory loss, and increasing suicide risk. Generally, the longer a person takes them the more likely the long-term adverse effects to nerves. 51. Gaist D, Jeppesen U, Andersen M, Garcia Rodriguez LA, Hallas J, Sindrup SH. Statins and risk of polyneuropathy: a case-control study. Neurology 2002 May 14;58(9):1333-7. 52. Wagstaff LR, Mitton MW, Arvik BM, Doraiswamy PM. Statin-associated memory loss: analysis of 60 case reports and review of the literature. Pharmacotherapy 2003 Jul;23(7):871-80. 53." - Byron J. Richards, Fight for Your Health: Exposing the FDA's Betrayal of America (Get the book.) "Covering up Cardiovascular Risk, suicide risk, and Seizures On February 9,2006, the Wall Street Journal reported that the FDA stated they would have an expert advisory panel review ADHD drugs. This review would be based on the fact that they identified eighty-one deaths (no causes listed) and fifty-four nonfatal cardiovascular events such as heart attacks associated with the ADHD drugs Adderall, Concerta, and Ritalin. The FDA also said it would present recent data on deaths and nonfatal serious events for all ADHD drugs, including Strattera, from Eli Lilly." - Byron J. Richards, Fight for Your Health: Exposing the FDA's Betrayal of America (Get the book.) "The MHRA data for Concerta suicide risk is as follows: "5 reports of suicidal ideation and three reports of suicidal attempt received. In addition there have been 3 reports of overdose." A six-year-old boy on Concerta for two months "experienced low mood and marked depression and tried to throw himself out a window. He recovered after drug withdrawal." The FDA also provided information about Concerta to the British: A further detailed analysis by the FDA found "8 reports of suicide ideation, 3 suicide attempts and 3 suicidal gestures..." - Byron J. Richards, Fight for Your Health: Exposing the FDA's Betrayal of America (Get the book.)

"That is when they discovered the suicide risk and proceeded to issue a warning against use by children.2 That action prompted further response in America by journalists, lawyers and regulators. This is where the story really took on some drama. The American College of Neuropsychopharmacology Contradicts the British Authorities In January 2004 the American College of Neuropsychopharmacology (ACNP) decided they had better issue a report in support of antidepressant use by children. (No group is more tied to the drug companies than the ACNP." - Dr. Timothy Scott, America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived (Get the book.)

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