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"This was misleading because if a drug causes sedation, then higher doses of the drug will cause more sedation, so if you are not comparing the same doses of the drug, you are not making a fair comparison. This allowed the company to promote Clarinex, which costs much more than the old drug, which went off patent and which in 2004 was bringing in close to a billion dollars a year in sales. Claritin and Clarinex, as far as consumers are concerned, are the same drug; so take Claritin and save some money."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Side effects like sedation, somnolence, fatigue, depression, lethargy, depressed mood, and hypersomnia result from global suppression of brain function. Even taking substantial overlap into account, these figures make clear that this drug disables the brain and mind, causing both physical and emotional manifestations of depression. Xanax XR was formulated in the hope that a long-acting preparation would cause fewer acute side effects. Clearly, the result failed to meet the hype. Also, if we add together the physical side effects that mimic drunkenness?"
- Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"On occasion this drug can also be used on a situational basis, for temporary sedation, if kids need to be sedated for a medical procedure, such as an intravenous drip. Trileptal is another good anticonvulsant that helps improve the moods of a relatively broad spectrum of children. It has been tested in kids as young as three, and is considered effective for seizures in very young children. It is also helpful for some autistic kids with bipolar features. Lamictal is a med I prescribe occasionally."
- Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.)

"Furthermore, the original antipsychotic meds, such as Thorazine and Haldol, were blunt instruments that often caused extreme sedation and other very unpleasant side effects. In response to the problems with the older antipsychotics, the newer class of atypical antipsychotics was created. These antipsychotics, or neuroleptics, can be quite helpful for many kids, particularly those who are notably unmanageable. The drugs can help these kids come back to reality enough to participate in their Healing Programs."

- Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.)

"A significant change in sedation, but not activation, occurred in patients in the fluoxetine 20-mg/day group compared with the placebo group. CONCLUSION: These data affirm that fluoxetine at 20 mg/day is efficacious, safe, and of similar activation potential when compared with placebo in patients with major depression. Extrapyramidal reactions and the selective serotonin-reuptake inhibitors. Caley CF. - School of Pharmacy, University of Connecticut, Hartford, USA. Ann Pharmacotber. 1997 Dec;31(12): 1481-9."
- Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)

"Adverse events were evaluated to determine the emergence of activation and/or sedation. RESULTS: At 20 mg/day, fluoxetine-treated patients demonstrated significantly greater remission and response rates and mean changes on HAM-D-17 total score and anxiety/somatization, retardation, and cognitive disturbance factor scores than placebo-treated patients (p < .001). The incidence of specific adverse events leading to discontinuation and the frequency of study discontinuations due to adverse events were similar among fluoxetine-treated and placebo-treated patients (6.1 % vs. 5.8%, p = .879)."

- Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)

"When the stress is not alleviated by sedation, which is always temporary, and when it is not addressed by a resolution of the underlying emotional conflict, disease symptoms begin to appear. The addiction problem and the emotional pain continue. In both cases, our collective bodies are mirroring the disease and imbalance in our lives so we can become balanced and grow in freedom as spirit, unencumbered by the ego. The Purpose of Emotional Pain Nothing in life is an accident; everything has a cause and a reason for being. The difficult part for us is realizing this."
- Ron Garner, Conscious Health: A Complete Guide to Wellness Through Natural Means (Get the book.)

"We do not want to feel pain, so we resort to methods of sedation; we try to escape. We do not know how to heal the conflict, so we continue to live unconsciously. But, "love, joy, and peace cannot flourish until you have freed yourself from mind dominance."6 Addiction and Disease As long as we continue to be unconsciously directed by our ego, we have very little control over our feelings and emotions; they happen to us. The ego feeds on struggle, and produces a constant flow of self-talk that produces pain in our emotional body."

- Ron Garner, Conscious Health: A Complete Guide to Wellness Through Natural Means (Get the book.)

"In general the sexual dysfunction and jitteriness that come with the SSRIs can be just as bad as the sedation and dry mouth that come with the old drugs. The success of the SSRIs has been mainly a triumph of marketing. All SSRIs work in the same way and differ only in properties such as how strongly they bind to the serotonin transporter, how long they remain in the bloodstream, and how they are metabolized. Escitalopram (Lexa-pro), which is essentially the same as citalopram (Celexa), was brought on the market in 2002 because Celexa was going off patent."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"It is used exclusively as an intravenous injection for preoperative sedation and memory impairment. Because Versed is used for anesthesia, it is given to the general population rather than to patients with psychiatric problems. Therefore, its powerful association with psychiatric reactions such as hostility confirmed that the drug, and not the patient, was the source of the problem."
- Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"This 14% substantive improvement came with myriad adverse physiological effects (diarrhea, insomnia and sedation) as well as higher rate of psychiatric adverse events (irritability, mania, and fatigue). The authors recommend drug-free treatment such as cognitive behavioral therapy or even a psychological placebo such as exercise.40 Another critic criticized the study's design, noting that the group which received Prozac with cognitive therapy, for which most benefit was claimed, was not double or even single-blinded."
- Gerald E. Markle and Frances B. McCrea, What If Medicine Disappeared? (Get the book.)

"Most biopsies are performed today using a flexible endoscope, passed orally under either conscious sedation or general anesthesia. This has the advantages of allowing direct visualization of the mucosa with a camera to look for changes suggestive of small bowel damage, such as notching or scalloping of the small bowel folds or lymphonodular hyperplasia [72]. Endoscopy also allows the endoscopist to look for other lesions, such as ulcers, esophagitis, or gastritis, which may help explain the patient's symptomatology."
- Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"In the paper, entitled "Activation and sedation in Fluoxetine Clinical Trials," the authors said that the drug may produce nervousness, anxiety, agitation or insomnia in 19 percent of patients, and sedation in 13 percent of patients. The British Medical Journal reported that the documents disappeared in 1994, during the case of Joseph Wesbecker, a printing press operator who had killed eight people at his Louisville, Kentucky, workplace five years before while taking fluoxetine. He then shot and killed himself."
- Andreas Moritz, Timeless Secrets of Health & Rejuvenation: Unleash The Natural Healing Power That Lies Dormant Within You (Get the book.)

"Flexible sigmoidoscopy takes less time, requires less dexterity and fewer support personnel, and is performed without sedation (although only a gastroenterologist could imagine it is not seriously unpleasant). The general feeling a decade ago was that annual fobt on three samples was advisable, relying on flexible sigmoidoscopy to verify positives. Then came the year 2000. Two papers appeared in the New England Journal of Medicine, cross-sectional studies that essentially reiterated the obvious."
- Nortin M. Hadler MD, Worried Sick: A Prescription for Health in an Overtreated America (Get the book.)

"All ablations require IV sedation or general anesthesia and may not be well tolerated in an office setting because of the pain of the procedure. Ablation technology continues to advance with the hopes of developing a procedure that can be done in the office. 3. Hysterectomy, surgical removal of the uterus, should be reserved for the woman with other indications for hysterectomy such as uterine fibroids, uterine prolapse, or atypical hyperplasia. When a hysterectomy is done for bleeding problems there is usually no need to remove the ovaries."
- Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"This last procedure is often done under sedation, because the doctor needs to pump air into the bowel in order to see inside it, and this can be uncomfortable. Ulcerative colitis is an example of an inflammatory bowel disease, and it is often serious, making people quite ill. Although they sound similar, this group of diseases shouldn't be (and usually isn't) confused with IBS. One illness that can mimic IBS is called gluten enteropathy, or celiac disease."
- Benjamin H. Natelson, M.D., Your Symptoms Are Real: What to Do When Your Doctor Says Nothing Is Wrong (Get the book.)

"Usually this procedure is done under sedation. One food sensitivity—lactose intolerance—is known to produce symptoms identical to IBS. In this disorder, your bowel lacks enough of the chemicals that break down the sugar lactose, which is found in milk products. A test will allow your doctor to diagnose this insufficiency. Incidentally, many people have experienced an isolated episode of food-related IBS after eating several hand-fuls of sugar-free candy quickly."

- Benjamin H. Natelson, M.D., Your Symptoms Are Real: What to Do When Your Doctor Says Nothing Is Wrong (Get the book.)

"Despite these side effects, I still use these as my first line drug for pain in three kinds of cases: when money is an issue (duloxetine is very expensive, but TCAs are cheap); major problems with recurrent headaches, for which low doses of TCAs often work wonders; and when the patient reports both pain and disrupted sleep. sedation is a side effect of one drug in this earlier class, amit-ryptilene—sometimes known by the brand name Elavil—and so it can help with sleep problems."

- Benjamin H. Natelson, M.D., Your Symptoms Are Real: What to Do When Your Doctor Says Nothing Is Wrong (Get the book.)

"Use of melatonin with benzodiazepenes, sedating antihistamines, sedating antidepressants and other sedating drugs may cause additive sedation and increase incidence of adverse effects. Use of melatonin with corticosteroids may interfere with the efficacy of the corticosteroids. HERBS Use of melatonin with valerian or kava kava may lead to additive sedation. NUTRITIONAL SUPPLEMENTS Use of melatonin with 5-hydroxytryptophan may lead to additive sedation. ALCOHOL Use of melatonin with alcohol may lead to additive sedation. FOOD No interactions are known. OVERDOSAGE None known."
- Sheldon Saul Hendler and David Rorvik, PDR for Nutritional Supplements (Get the book.)

"Examples of surgeries that do not require general anesthetic are (1) a breast biopsy, which can be done under local numbing of the surgical area with intravenous (IV) sedation; (2) an inguinal hernia repair, which can be done with an epidural or "spinal" or with heavy IV sedation; (3) any extremity (arm or leg) surgery, which can be done under regional block with IV sedation; (4) a vaginal hystetectomy or a transurethral resection of the prostate gland (TURP), which can be done with epidural plus IV sedation."
- The Life Extension Editorial Staff, Disease Prevention and Treatment (Get the book.)

"Effect Can cause liver damage Can increase effects of alcohol Stomach bleeding Can cause extreme sedation Can cause extreme sedation Increased risk of seizures Increases effects of alcohol Low blood pressure, slowed breathing Upset stomach, hypoglycemia, headache Internal bleeding Can cause extreme sedation Increases effects of drug and alcohol Reduces the effect of the tetracycline Can cause extreme sedation sequestrants for lowering cholesterol levels, cholestipol and cholestyramine."
- Earl L. Mindell, RPh, PhD with Virginia Hopkins, MA, Bottom Line's Prescription Alternatives (Get the book.)

"The secondary effect of stimulation is sedation. Thus it is common to feel tired when [people] first [start on] the raw diet. It is not that the raw diet is making them tired; it is that they are actually 'coming down' off of the influence of coffee, refined sugars, meats and other stimulating foods" (The 80/10/10 Diet, p. 62). Possible Detoxification Symptoms While serving as head instructor and exam corrector for many of the 3,000 students taking T. C."
- Susan E. Schenck, The Live Food Factor: The Comprehensive Guide to the Ultimate Diet for Body, Mind, Spirit & Planet (Get the book.)

"Zyprexa provides heavy sedation and the doctor probably hoped to suppress both the nightmares and the sleepwalking. Mr. Dawson was a wealthy businessman who was determined to use his resources to rescue his daughter from her desperate plight. Within days of arriving in town, he and his wife had taken Regina to a well-connected professor of psychiatry they found on a "Best Doctors" list. The doctor had examined Regina and told her parents not to be concerned about the "routine medication effects" of Zyprexa."
- Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"Chlor-Trimeton, sold without a prescription) would be as effective as, or more effective than, Claritin, without causing sedation. As the patent to Claritin expired, it was made available without prescription, and Schering-Plough's marketing support for the drug decreased precipitously. The first drug to come of age in the new era of drug advertising was the first to fade away—it no longer made business sense for its manufacturer to sustain the huge advertising budget."
- John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"The surgery doesn't require heavy sedation, a large incision or stitches. Ask your doctor about this procedure for treating fibroids. • Alternative Treatment Instead of surgery, a doctor may prescribe drug therapy for keeping uterine fibroids in check. Leuprolide, a hormone-balancing drug approved for treating prostate cancer, has been used in some instances to treat uterine fibroids. For more information on this type of treatment, ask your gynecologist or family physician. VAGINAL DRYNESS • Sexual Healing jR."
- Bottom Line Books, Uncommon Cures For Everyday Ailments (Get the book.)

"August 1989: Additional feedback regarding the fluoxetine [Prozac] review by the Commission A [Germany] The counterindication because of acute suicidality should become a warning whereby the physicians should be advised that in the absence of sedation, the risk of higher suicidality should be taken into account."
- Kelly Patricia O'Meara, Psyched Out: How Psychiatry Sells Mental Illness and Pushes Pills That Kill (Get the book.)

"In reality, no specific improvements have occurred in the underlying depression, psychosis, or anxiety. Instead, the brain has been partially disabled, artificially changing the individual's mood and rendering the patients less able to feel, to perceive, or to express their underlying mental condition or outlook. Psychoactive drugs, including psychiatric medications, not only impair the individual's ability to perceive their adverse effects but also impair the individual's ability to perceive his or her emotional problems."
- Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"Among the documents reported by freelance journalist Jeanne Lenzer in the BMJ include "a report of 8 November 1988," entitled "Activation and sedation in Fluoxetine Clinical Trials," that found that in clinical trials "38% of fluoxetine-treated patients reported new activation but 19% of placebo-treated patients also reported new activation, yielding a difference of 19% attributable to fluoxetine."
- Kelly Patricia O'Meara, Psyched Out: How Psychiatry Sells Mental Illness and Pushes Pills That Kill (Get the book.)

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