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"The man who had become manic on large doses of a very mild stimulant, pseudoephedrine, was now being prescribed very large doses of an exceptionally strong stimulant, amphetamine. Meanwhile, Vernon remained on the Klonopin he'd been taking for years. A few months after prescribing the Adderall, Vernon's psychiatrist decided to cut the dose in half to 30 mg—the usual maximum. Simultaneously, he started Vernon on Strattera 80 mg per day, the ADHD treatment that's been advertised by Eli Lilly as "nonstimulant."
- Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"The DEA has allowed itself to be used as an agent for the largest pharmaceutical companies to rid the market of competition to their ephedrine and pseudoephedrine containing cough and cold remedies. It has destroyed some fifty companies, causing unemployment and significant economic hardship. The only institutions benefiting from this wholesale destruction of a segment of the market are the pharmaceutical companies that supply the pharmacies and big box stores. The enforcement activity has no effect on domestic supply or use of illicit methamphetamines."
- Jonathan W. Emord, The Rise of Tyranny (Get the book.)

"Over-the-counter drugs for the treatment of asthma and upper respiratory ailments contain ephedrine or pseudoephedrine. Ephedrine and pseu- doephedrine are used in the making of illicit methamphetamines. Although over-the-counter cough and cold remedies are almost never used in the making of methamphetamines (representing less than 1% of the domestic source of the illicit drug), the DEA has made elimination of certain sources of cough and cold remedies an 183 enforcement priority."

- Jonathan W. Emord, The Rise of Tyranny (Get the book.)

"At the DEA, that favored regulatee is again the pharmaceutical industry, which now enjoys above market rates of return due to DEA enforcement to remove from the market independent suppliers of ephedrine and pseudoephedrine containing cough and cold remedies. At CMS, that favored regulatee is the insurance industry which, in turn, is a proxy for the pharmaceutical industry. We can perceive abuses whenever agency actions sacrifice fundamental rights to life, liberty, and property to yield outcomes favorable to a preferred regulatee."

- Jonathan W. Emord, The Rise of Tyranny (Get the book.)

"Some OTC products, such as Advil Cold and Sinus Caplets and Tylenol Sinus Daytime, contain pseudoephedrine along with other active ingredients. Dangers: Increased blood pressure.. .rapid heart beat.. .insomnia. What to do: Avoid caffeinated beverages because they can increase restlessness and insomnia. Do not use pseudoephedrine if you have taken an MAO inhibitor (a type of antidepressant) within the last two weeks—the combination can cause dangerously high blood pressure."
- Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.)

"Pseudoephedrine Pseudoephedrine relaxes bronchial muscle like ephedrine, but exerts weaker effects on the heart and central nervous system. pseudoephedrine is often recommended in preference to ephedrine in the treatment of chronic asthma, as it has fewer side effects.3 Pseudoephedrine has also demonstrated a significant antiinflammatory effect in various experimental models.45 Other ephedra alkaloids, including ephedrine, also exhibit antiinflammatory activity, but at much lower potency."
- Michael T. Murray, N.D., The Healing Power of Herbs: The Enlightened Person's Guide to the Wonders of Medicinal Plants (Get the book.)

"Do not use pseudoephedrine if you have taken an MAO inhibitor (a type of antidepressant) within the last two weeks—the combination can cause dangerously high blood pressure. Consult a doctor if you have hypertension, an overactive thyroid gland or difficulty urinating due to an enlarged prostate gland—pseudoephedrine can aggravate these conditions. DEXTROMETHORPHAN An antitussive that relieves a dry (nonproductive) cough caused by a cold or flu. Popular brands: Benylin Cough Suppressant, Robitussin DM Cough Syrup, Sucrets 8-Hour Cough Suppressant, Vicks 44 Cough Relief."
- Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.)

"Pseudoephedrine plus ibuprofen may be given to relieve some of the symptoms of a cold. pseudoephedrine is a decongestant that helps improve breathing by constricting the blood vessels in the mucosa of the respiratory tract and relaxing the bronchial (breathing) tubes. These two actions allow air to flow in and out more freely. Ibuprofen helps reduce inflammation and relieve pain. Possible Side Effects Pseudoephedrine's side effects include rapid heartbeat, irregular heartbeat, weakness, and tremor. Ibuprofen's side effects include headache, fluid retention, rash, and kidney failure."
- Frederic Vagnini, M.D. and Barry Fox, Ph.D., The Side Effects Bible: The Dietary Solution to Unwanted Side Effects of Common Medications (Get the book.)

"Pseudoephedrine Pseudoephedrine exhibits bronchodilating activity similar to ephedrine, but has weaker pressor, cardiac, and central nervous system effects. pseudoephedrine is often recommended over ephedrine in the treatment of chronic asthma as it has fewer side-effects.3,4 Pseudoephedrine has also demonstrated significant antiinflammatory effects in various experimental models.8-10 Other ephedra alkaloids, including ephedrine, also exhibited anti-inflammatory activity, but at much lower potency."
- Michael T. Murray, ND, Textbook of Natural Medicine 2nd Edition Volume 1
(Get the book.)

"One of the medications, pseudoephedrine, is a stimulant that can cause maniclike behavior. Dr. Kirklander took several times the recommended dose. (Although these drug reactions appear to be uncommon, I have personally evaluated two cases of psychosis induced by this common cold medication.) The other nonprescription medication was a steroid preparation (an-drostenedione/androstenediol mixture). On March 11,2005, the FDA issued a warning to manufacturers to stop distributing products containing androstenedione because of its steroidal effects."
- Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"The oral decongestant pseudoephedrine (Sudafed) may help relieve nasal congestion, while antihistamines such as diphenhydramine (Benadryl), brompheniramine (Dimetapp), chlorpheniramine (Chlor-Trimeton), and loratadine (Claritin) might help dry excess mucous and reduce sneezing. Cromolyn sodium (Nasalcrom) is used as a nose spray to prevent hayfever symptoms. Prescription antihistamines are often prescribed for relief of hay fever symptoms. These include cetirizine (Zyrtec), desloratadine (Clarinex), and fexofenadine (Allegra)."
- Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"People with insomnia are typically advised to avoid stimulants such as caffeine (found in coffee, tea, and soda), diet pills containing ephedra, and over the counter cold and allergy products containing pseudoephedrine. Dietary changes that may be helpful Caffeine is a stimulant.1 The effects of caffeine can last up to 20 hours,2 so some people will have disturbed sleep patterns even when their last cup of coffee was in the morning. Besides regular coffee, black tea, green tea (page 686), cocoa, chocolate, some soft drinks, and many over-the-counter pharmaceuticals also contain caffeine."

- Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"It should also be noted that products containing ephedrine or pseudoephedrine are prohibited by a number of sporting authorities.36 Most of the evidence purported to support the use of ma huang for the indications described above comes from work carried out using ephedrine or pseudoephedrine alone and not the herb ma huang. While a substantial amount of historical and empirical evidence exists regarding this herb's medicinal usefulness, it is primarily restricted to the treatment of asthma, bronchitis and conditions of the upper respiratory tract."
- Heather Boon, BScPhm, PhD and Michael Smith, BPharm, MRPharmS, ND, The Natural Medicine Guide to the 50 Most Common Medicinal Herbs (Get the book.)

"The Ephedras have been shown to contain various chemical stimulants, including the alkaloids ephedrine, pseudoephedrine and norpseudoephedrine, as well as various tannins and related chemicals. The concentrations of these alkaloids depends upon the particular species of Ephedra used. Ephedrine and pseudoephedrine are amphetamine-like chemicals used in OTC and prescription drags. Many of these stimulants have known serious side effects. Ma huang is sold in products for weight control, as well as in products that boost energy levels."
- American Medical Publishing, Prescription Medicines, Side Effects and Natural Alternatives (Get the book.)

"Synthetic ephedrine and pseudoephedrine are currently found in pharmaceuticals including Contac, Sinutab, Sudafed, Actifed, and Robitussin PE. Topically, the resin from the ephedra shrub can be applied to cuts to promote healing. Edible Uses The red berries on the plant are the only parts considered edible. Other Uses Guards of Genghis Khan's army used ephedra to help them stay awake (they would be beheaded if caught dozing!). Taoist monks use ephedra to sharpen awareness. The herb also has been smoked as an aphrodisiac."
- Brigitte Mars, A.H.G., The Desktop Guide to Herbal Medicine: The Ultimate Multidisciplinary Reference to the Amazing Realm of Healing Plants, in a Quick-study, One-stop Guide (Get the book.)

"Medical treatments Over the counter drugs include antihistamines such as diphenhydramine (Benadryl), loratadine (Claritin), and chlorpheniramine (Chlor-Trimeton), as well as the decongestant pseudoephedrine (Sudafed). Topical nasal decongestants such as Oxymetazoline (Afrin) and Phenylephrine (Neo-Synephrine) may be used for a few days without harmful side effects. Saline-based nasal sprays such as Ocean, Ayr, and Dristan Saline Spray may be used to soothe inflamed tissue due to allergies. The nasal solution cromolyn sodium (Nasalcrom) may be used to prevent future allergy attacks."
- Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"PSEUDOEPHEDRINE PLUS IBUPROFEN (soo-doe-e-FED-rin, eye-byoo-PRO-fen) Brand Names: Advil Cold & Sinus Caplets, Dimetapp Sinus Caplets, Dristan Sinus Caplets, Motrin IB Sinus, Sine-Aid IB About pseudoephedrine plus Ibuprofen Being cold does not give you a cold, and having a cold does not make you cold: The common cold has litde to do with cold temperatures. Colds are caused by viruses, and the rhinovirus is the usual suspect. This virus leaves an infected body via the nasal secretions, typically by hitching a ride on the individual's hands, which pass it the next victim's hands."
- Frederic Vagnini, M.D. and Barry Fox, Ph.D., The Side Effects Bible: The Dietary Solution to Unwanted Side Effects of Common Medications (Get the book.)

"Decongestants: pseudoephedrine is an effective decongestant but should not be used by people with hypertension or anxiety. Antihistamines: To treat sneezing due to allergies, take an antihistamine such as Benadryl™ at bedtime and Claritin™ during the day to suppress the sneezing. Quercetin is a natural supplement that also treats sneezing caused by allergies; take 1 g twice a day. TRADITIONAL CHINESE MEDICINE Herbs: If sneezing persists, try some tea formulas that are convenient and effective for reducing this condition. If you have an allergic reaction to any herb, stop drinking the tea."
- Marshall Editions, 1000 Cures for 200 Ailments: Integrated Alternative and Conventional Treatments for the Most Common Illnesses (Get the book.)

"Thanks to its active alkaloids ephedrine and pseudoephedrine, Ephedra has proven itself extremely useful in treating a number of conditions, including asthma and hay fever. In Chinese medicine, Ephedra is also used—always in conjunction with other supporting herbs—as a tool to regulate water circulation, relieve edema, stop coughing, disperse coldness and dampness from areas of the body, as well as other holistic purposes (Chinese medicine never uses one chemical to treat one condition; herbs are always used synergistically to support the body's own healing systems and processes)."
- Mike Adams, Natural Health Solutions (Get the book.)

"Doctors sometimes prescribe decongestants containing pseudoephedrine as a treatment for urge incontinence. pseudoephedrine makes the urethral muscles clamp down, which helps prevent involuntary urine flow. (As mentioned above, decongestants can aggravate overflow incontinence.) If I had urge incontinence, I'd rather go with the original source of pseudoephedrine: Chinese ephedra (ma huang). Unfortunately, the FDA is considering restricting access to Chinese ephedra because of a handful of deaths—many involving people who took huge doses to experience amphetamine-like intoxication."
- James A. Duke, Ph.D., The Green Pharmacy Anti-Aging Prescriptions: Herbs, Foods, and Natural Formulas to Keep You Young (Get the book.)

"These include ephedrine, phenylpropanolamine, pseudoephedrine, phenmetrazine, and phentermine (high doses). Their recent use should be ruled out when test results are positive. Clinical Management: When screening for amphetamines using the EMIT assay, recent use of ephedrine should be ruled out when test results are positive. overdosage Life-threatening poisonings are seen with very high dosages of the drug (over 100 g, lethal dosage with oral administration corresponding to approximately 1 to 2 g L-ephedrine)."
- Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.)

"Coadministration of indirect-acting sympathomimetics such as pseudoephedrine and phenylpropanolamine with MAOIs has resulted in severe hypertension (Smookler & Bermudez, 1982) and one case has been reported of severe agitation, tachycardia, hypotension, and fever with concomitant use of ephedrine and a MAOI (Dawson et al, 1995). Patients who take MAOIs with Ma Huang may be predisposed to hypertensive crisis and other symptoms consistent with excessive sympathomimetic amine activity. Other potential reactions include cardiac arrhythmias, chest pain, hyperpyrexia, and death."

- Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.)

"It produces vasoconstriction, cardiac stimulation, acute increases in blood pressure, tachycardia, mydriasis, insomnia, vertigo, headache, and nervousness. pseudoephedrine enhances beta-2-agonist activity including bronchodilation, but also has alpha-agonist activity that helps with nasal constriction (White et al, 1997). Clinical trials demonstrated efficacy of Ma Huang or ephedrine in the treatment of asthma and obesity; the primary current applications of Ma Huang are in the treatment of asthma and hay fever, the common cold, and as a weight loss aid."

- Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.)

"Clinical Management: Concomitant use of Ma Huang and pseudoephedrine should be avoided, as it may lead to excessive adrenergic stimulation, which may increase blood pressure, heart rate, and the risk of cardiac arrhythmia. Reserpine: Concomitant ephedrine and reserpine therapy has been reported to result in a decrease in the effectiveness of ephedrine due to the depletion of norepinephrine by reserpine (Hansten & Horn, 1990). Patients receiving reserpine may have a diminished response to ephedrine. Secale alkaloid derivatives or oxytocin: Development of high blood pressure."

- Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.)

"A decongestant such as pseudoephedrine (found in Sudafed and other products) may also be helpful, but remember, these medications are dehydrating (and so is the lack of humidity in an airplane cabin). If you use them, be sure to drink plenty of water and juice during the flight, and skip the cocktail and coffee, as alcohol and caffeine also are dehydrating. Q Always wear ear protection (disposable plugs or an earphone-style headset) when using loud appliances such as power tools or lawn mowers; and when you know you will be exposed to sudden loud noises, such as when shooting a gun."
- Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)

"As popular as pseudoephedrine may be, there are some side effects to be alert for. Many people complain of insomnia, anxiety, agitation, headache, nausea, dizziness, and tremor. The most serious adverse reactions are elevated blood pressure and irregular heart rhythms. Men with prostate enlargement must avoid this decongestant because it can make urination much more difficult. Conclusions Allergies don't get the respect they deserve. When you complain about your congestion, most friends and family members will barely sympathize."
- Joe Graedon, M.S. and Teresa Graedon, Ph.D., Best Choices From the People's Pharmacy (Get the book.)

"Taking Claritin-D left me completely unable to fall asleep. I was literally up all night with a racing heartbeat. I have had insomnia problems before, so I did not immediately associate this with the medication and continued to take it for 5 days. I was so sleep deprived that I couldn't work. I finally read the warning about nervousness, dizziness, or sleeplessness. I called my doctor, who said I should switch to Claritin fnon-D). On this drug I sleep like a baby. I found that some OTC allergy medicines I had taken for years also contain pseudoephedrine."

- Joe Graedon, M.S. and Teresa Graedon, Ph.D., Best Choices From the People's Pharmacy (Get the book.)

"Chemistry: flavonoids: lucenin 1, vicenin 2, and an array of tannins Medicinal Uses: Even though our western Mormon tea contains no ephedrine and only traces of pseudoephedrine, the plant still is useful as a sinus passage decongestant, and in a limited capacity, as a bronchial dilator. Apparently, Mormon tea contains enough "sub-ephedrines" to make this effect noticeable. In addition, the plant's flavonoid content may contribute to these properties. Take the tea or tincture throughout allergy season for hayfever."
- Charles W. Kane, Herbal Medicine of the American Southwest (Get the book.)

"Sympathomimetics such as pseudoephedrine are sometimes taken in tablet or syrup form, as in Actifed, CoTylenol, Drixoral, and Sudafed. They may also be combined with antihistamines in medicines taken by mouth, such as Allegra-D {pseudoephedrine and fenofexadine), Sudafed Plus (pseudephedrine and tripolidine), and Claritin-D {pseudoephedrine and loratidine). When taken by mouth, the sympathomimetic helps to overcome the main side effect of the antihistamine, drowsiness. (See page 438 for side effects."
- Jonathan Brostoff M.D., Linda Gamlin, Food Allergies and Food Intolerance: The Complete Guide to Their Identification and Treatment (Get the book.)

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