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"Benign prostatic hypertrophy occurs in all men as they age, although it is not known why the prostate enlarges over time. Symptoms of prostate enlargement can include frequent urination, especially during the night; pelvic pain; burning; impotence; and difficulty starting and stopping urination. Problems urinating can lead to urine remaining and becoming stagnant in the bladder, causing infection of the bladder and the kidneys. See also bladder infection and kidney stress." - Tom Bohager, Everything You Need to Know About Enzymes to Treat Everything from Digestive Problems and Allergies to Migraines and Arthritis (Get the book.)

"Patient Outcomes Research Team for prostatic Diseases. Ann. Oncol. 9, 1279-1282. 4. Chodak, G. (2006). Prostate cancer: Epidemiology, screening, and biomarkers. Rev. Urol. 8, S3-S8. 5. Parkin, D. M., Whelan, S. L., Ferlay, J., Teppo, L., and Thomas, D. B. (2002). "Cancer Incidence in Five Continents," Vol VIII. IARC Sci. Pub., No. 155, IARC Lyon, France. 6. American Cancer Society. (2007). "Cancer Facts and Figures 2007." American Cancer Society, Inc., Atlanta, GA. 7. Hankey, B. F., Feuer, E. J., Clegg, L. X., Hayes, R. B., Legler, J. M., Prorok, P. C, Ries, L. A., Merrill, R. M." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"Prostatic secretions contain a high concentration of zinc. Zinc also tones down the activity of the 5-alpha-reductase enzyme, which, you may recall, fuels the conver- Natural Prescription for Benign Prostate Hyperplasia Saw palmetto: 320 mg (160 mg, twice a day) CAN BE COMBINED WITH (APPROXIMATE VALUES): Pygeum: 1 00-200 mg (50-1 00 mg, twice a day) Stinging nettles: 300 mg (1 50 mg, twice a day) Beta-sitosterol: 100-300 mg (150 mg, twice a day) Zinc: 50 mg to start; reduce to 30 mg after a few months sion of testosterone to dihydrotestosterone." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Benign prostatic Hyperplasia (enlarged prostate) S& enlargement of the prostate gland is one of the most common conditions affecting men past the age of 50. Known to doctors as benign prostatic hyperplasia (BPH), this problem causes various urinary difficulties. Men with BPH tend to urinate frequently, often one or more times in the middle of the night. They also experience difficulty starting their urine flow and have reduced pressure behind their urinary stream. If BPH becomes severe, it can result in obstruction of urine flow, which is a medical emergency." - Jonathan V. Wright, M.D. and Alan R. Gaby, M.D., Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing (Get the book.)

"BENIGN prostatic HYPERPLASIA (BPH) • A Less Invasive Surgical Alternative • Bark with a Bite ~Pygeum africanum—the bark of an African evergreen tree—works equally well on prostatitis and BPH. This herb limits the production of DHT, which increases oil in the glands, makes your hair fall out, and enlarges the prostate. Also, pygeum africanum has a mild antibiotic effect, which makes it particularly effective against bacteria-induced prostatitis. Typical dosage is 50 to 100 mg in extract form twice a day." - Bottom Line Books, Uncommon Cures For Everyday Ailments (Get the book.)

"Dysplastic nevus Melanoma Normal prostate Prostatic hyperplasia -> prostatic intraepithelial neoplasia Prostate cancer ASCUS = atypical squamous cells of unknown significance. Figure 10. The spectrum from normal to cancer. In a simple black and white world, a diagnosis would involve only two assessments: normal and cancer. There would be no room for disagreement. In the real world, however, there is a spectrum of abnormalities?a huge gray area—between normal cells and invasive cancer. Pathologists have long recognized that this gray area exists." - H. Gilbert Welch M.D. M.P.H., Should I Be Tested for Cancer? Maybe Not and Here's Why (Get the book.)

"Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP), Cancer Res, 61: 6777-6782. Miksicek, R. J., 1993, Commonly occurring plant flavonoids have estrogenic activity, Mol Pharmacol, 44: 37-43. Miksicek, R. J., 1995, Estrogenic flavonoids: structural requirements for biological activity, Proc Soc Exp Biol Med, 208: 44-50. Minden, A., Lin, A., McMahon, M., Lange-Carter, C, Derijard, B., Davis, R. J., Johnson, G. L., and Karin, M." - Erich Grotewold, The Science of Flavonoids (Get the book.)

"A marker for prostatic cell differentiation, prostate acid phosphatase, was significantly increased after 48 hours of treatment. The compound "strongly inhibits growth and induces differentiation in human prostate cancer cells," said the researchers. Dr. Shamsuddin and his team investigated the effect of IPg on natural killer cells (NK), which are immune cells produced in the bone marrow and matured in the thymus gland that can recognize and quickly destroy virus and cancer cells." - Freedom Press, Natural Cancer Cures: The Definitive Guide to Using Dietary Supplements to Fight and Prevent Cancer (Get the book.)

"Slowing tumorigenic progression in TRAMP mice and prostatic carcinoma cell lines using natural anti-oxidant from spinach, NAO—A comparative study of three anti-oxidants. Toxicologic Pathology. 2003 Jan/Feb;31(l):39-51. Rai A, Mohapatra SC, Shukla HS. Correlates between vegetable consumption and gallbladder cancer. Eur J Cancer Prev. 2006 Apr;15(2):134-137. Sani HA, Rahmat A, Ismail M, Rosli R, Endrini S. Potential anticancer effect of red spinach (Amaranthus gangeticus) extract. Asia Pacific Journal of Clinical Nutrition. 2004;13(4):396-400. Seddon JM et al." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"Note: Seminal fluid, prostatic fluid and sperm together make up semen. Forget about Cigarettes and Sex Not long ago, in a respected urology journal, researchers reported that sperm cells of men who regularly smoked cigarettes couldn't swim as efficiently as those of nonsmokers. What's more, it turned out that smokers' sperm cells didn't perform as well on tests that gauge the cell's ability to penetrate the outer shell of a female's egg." - Bottom Line Books, Uncommon Cures For Everyday Ailments (Get the book.)

"It is of interest that circulating levels of P-carotene were shown to be significantly correlated with the levels in prostatic tissue [280]. Finally, an intervention trial in the United States found no effect of P-carotene supplementation on prostate cancer risk [281], though a similar trial in Finland found a decreased risk among nondrinkers of alcohol but an increased risk among drinkers [269]. A carotenoid of particular interest with regard to prostate cancer is lycopene, found primarily in tomatoes and tomato products (other food sources include watermelon, grapefruit, and guava)." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.) "Determination of the distribution of zinc and cadmium in cellular fractions of BPH, normal prostate and prostatic cancers of different histologies by atomic and laser absorption spectrometry in tissue slices. Urol. Res. 12, 253-256. 159. Costello, L. C, Franklin, R. B., Feng, P., Tan, M., and Bagasra, O. (2005). Zinc and prostate cancer: A critical scientific, medical, and public interest issue (United States). Cancer Causes Control 16, 901-915. 160. Habib, F. K., Mason, M. K, Smith, P. H., and Stitch, S. R. (1979). Cancer of the prostate: Early diagnosis by zinc and hormone analysis? Br. J." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"Prostate Cancer prostatic Dis. 2006;9(2):147-152. Lim GP, Chu T, Yang F, Beech W, Frautschy SA, Cole GM. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. JNeuro Sci. 2001;21:8370-8377. Ng TP et al. Curry consumption and cognitive function in the elderly. Am J Epidemiol. 2006 Nov l;164(9):898-906. Peschel D, Koerting R, Nass N. Curcumin induces changes in expression of genes involved in cholesterol homeostasis. ]Nutr Biochem. 2007 Feb; 18(2):113—119. Singletary K." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"For more information on benign prostatic — hyperplasia, visit the National Kidney and Urologic Diseases Information Clearinghouse at http://kidney.niddk.nih.gov. Click on "Kidney and Urologic Diseases," and scroll down to "BPH Benign prostatic Hyperplasia." Music Keeps Heartbeat Humming Peter Sleight, MD, department of cardiovascular medicine, University of Oxford, Oxford, England. Vincent Marchello, MD, vice president, medical affairs, Metropolitan Jewish Health System, and assistant professor of clinical medicine, Mount Sinai School of Medicine, both in New York City. Heart." - Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.)

"As a major constituent of prostatic fluid [157-159], zinc is essential for normal prostate function. Zinc is also essential for normal testicular function, and high levels of zinc have been proposed to increase the production of testosterone, leading to enhanced tissue growth in the prostate. Plasma levels of zinc have been positively correlated with testosterone and dihydrotestosterone levels in men [160, 161]. Furthermore, in the rat prostate, zinc has been shown to increase 5a-reductase activity [162] and to potentiate androgen receptor binding [163]." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"Some men may initially present with fever and uncomfortable prostatic symptoms, but antibiotics don't remedy the problem. About 9% of men have prostatitis at any given time. About half of all men will experience prostatitis during their lifetime, some beginning as young as age 18. Fortunately, prostatitis often subsides on its own over time. [British Journal Urology 90: 678-81,2002] Treatment for prostatitis Standard treatment for prostatitis is finasteride (Propecia) or alpha blockers. Finasteride shrinks the prostate gland by about 20% and over time helps with symptoms of prostatitis." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.)

"Effects of the lipidosterolic extract of Serenoa repens (Permixon (R)) on human prostatic cell lines. In: Prostate 29(4):219-230. 1996. Rhodes L, Primka RL, Berman CH, Vergult F, Gabriel M, Pierre-Malice M, Gibelin B, Comparision of Finasteride (Proscar(R)), a 5alpha-reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5alpha reductase inhibition. In: Prostate. Schilcher H, (1987) Moglichkeiten und Grenzen der Phytotherapie am Beispiel pflanzlicher Urologika. Urologe [B] 27:316-319. Schilcher H, (1987) Pflanzliche Diuretika. Urologe [B]27:215-222." - Joerg Gruenwald, Ph.D., PDR for Herbal Medicines (Get the book.)

"High cholesterol (page 223) Menkes' disease (page 311) (injectable copper histidine) Osteoporosis (page 333) Wound healing (page 319) þftft Athletic performance (page 43) Benign prostatic hyperplasia (page 58) Cardiac arrhythmia (page 93) Hypoglycemia (page 251) Peripheral vascular disease (page 352) Rheumatoid arthritis (page 387) Sprains and strains (page 412) Who is likely to be deficient? Many people consume slightly less than the "safe and adequate range" of copper, 1.5-3.0 mg per day." - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"This study is a preliminary indication that a low-fat diet is one of the factors which can lower the risk of prostatic cancer," Dr. Hill told us. "By reducing total calorie intake, and substituting fruit and vegetable calories for animal calories, a high-risk prostatic cancer group was switched to a low-risk one." Zinc and the Prostate But if those who suffer from prostate diseases have too much fat in their diets, one nutrient they apparently have too little of is zinc. Normally, there is an extraordinary concentration of zinc in healthy human prostatic fluid." - Mark Bricklin, The Practical Encyclopedia of Natural Healing (Get the book.)

"Benign prostatic Hypertrophy According to Dr. Kruzel, by the age of 50, about 30% of men will start to experience difficulties with urination related to enlargement of the prostate gland or benign prostatic hypertrophy (BPH). Increases in the number of times a man has to urinate, along with a frequent sensation of having to urinate (especially at night), are among some of the early signs. In addition, a reduction in the force and caliber of urination is also characteristic of prostatic enlargement." - Larry Trivieri, Jr., Alternative Medicine the Definitive Guide, Second Edition (Get the book.)

"Prostate Cancer and prostatic Diseases 9: 25-29, 2006 Prostate cancer diagnosis is a major life altering experience. Among the problems caused by diagnosis alone are: • Inconvenience • Uncertainty • Anxiety • Discomfort • Costs • Embarrassment with incontinence • Impotence and loss of sexual function PSA testing Prostate Specific Antigen (PSA) testing was introduced around 1991. The normal prostate gland secretes PSA in the seminal fluid, which eventually can be found in trace amounts in the blood circulation." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.) "Prostate Cancer and prostatic Diseases 9: 192-194, 2006] Most men concerned about recurrence of prostate cancer are disturbed to find that PSA is not a reliable marker. An interesting study conducted by Norwegian researchers was published in 1998. The study involved 1,135 specimens of prostate tissue removed during surgical procedures performed between 1974 and 1975. The patients who were operated on were followed for up to 20 years. Then microscopic examination was performed, and only 83 of these 1,135 patients developed new tumors." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.) "The harsh reality is that it is difficult, if not impossible, to differentiate prostatic inflammation (prostatitis) from cancer, and benign or idle forms of cancer from aggressive, life-threatening malignancies. Various experts now claim that "PSA may no longer be an effective marker for early-stage tumors, with PSA elevation failing to discriminate tumor-specific characteristics from benign gland enlargement." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.)

"In folk medicine, it is used internally for acute exacerbations of pulmonary tuberculosis, diabetes, enlargement of the liver, gout, hemorrhoids, internal bleeding, nervous bronchial asthma, prostatic hypertrophy, and rheumatism. External uses in folk medicine include inflammation of the mouth and pharyngeal cavity and the treatment of festering wounds." - Joerg Gruenwald, Ph.D., PDR for Herbal Medicines (Get the book.)

"Clinical studies on the palliative treatment of prostatic adenoma with extract of Urtica root. Phytotherapy Research 1991; 5: 267-269. 11. Stahl HP. The treatment of prostatic nycturia with standardized extract of Radix Urticae (ERU) [in German]. Zeitschrift All-gemeiner Medizin 1984; 60: 128-132. 12. Dathe G, Schmid H. Phytotherapy for benign prostatic hyperplasia (BPH): double-blind study with extract Radicus Urticae (ERU) [in German]. Urologe B 1987; 27: 223-226. 13. Berges RR, Windeler J, Trampisch HJ, et al." - Robert S. McCaleb, Evelyn Leigh, and Krista Morien, The Encyclopedia of Popular Herbs (Get the book.) "Saw palmetto shown to shrink prostatic epithelium. Urology Times 1999; 27(6): 1,42. 4. Marks LS, Tyler VE. Saw palmetto extract: newest (and oldest) treatment alternative for men with symptomatic benign prostatic hyperplasia. Urology 1999; 53: 457-4-61. 5. Champault G, Bonnard AM, Cauquil J, et al. A double-blind trial of an extract of the plant Serenoa repens in benign prostatic hyperplasia. Actualite Therapeutique 1984; 6: 407-4-10. 6. Carraro JC, Raynaud JR Koch G, et al." - Robert S. McCaleb, Evelyn Leigh, and Krista Morien, The Encyclopedia of Popular Herbs (Get the book.)

"Zinc also reduced prostatic size in an animal study but only when given by local injection.15 Although the research supporting the use of zinc is weak, many doctors recommend its use. Because supplementing with large amounts of zinc (such as 30 mg per day or more) may potentially lead to copper (page 499) deficiency, most doctors recommend taking 2 to 3 mg of copper per day along with zinc. Are there any side effects or interactions? Refer to the individual supplement for information about any side effects or interactions." - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.) "Also avoid this therapy in the presence of prostatic calculi (stones), a condition common in elderly men in which small calcifications develop in the prostate. Controlled studies indicate psychological factors, such as anxiety (page 30) and depression (page 145), occur more frequently in men with NBP and PD.40, 41' 42 This may be because psychological factors contribute to the development of NBP and PD, or perhaps they occur as a result of prostatitis. Nonetheless, some practitioners believe psychotherapy may help reduce symptoms in these cases." - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"Lichius JJ et al, Inhibition of experimentally induced mouse prostatic hyperplasia by methanolic extracts of Urtica dioica roots. In: PM 61(Abstracts of 43rd Ann Congr):89. 1995. Lichius JJ, Muth C, A new biological evaluation of Urtica dioica root-extracts. In: PM 62, Abstracts of the 44th Ann Congress of GA, 20. 1996. Miersch WDE, Benigne Prostatahyperplasie. In: DAZ 133(29):2653. 1993. Nahrstedt A (1993) Pflanzliche Urologica - eine kritische Ubersicht. Pharm Z 138: 1439-1450. Noske HD (1994) Die Effektivitat pflanzlicher Prostatamittel am Beispiel von Brennesselwurzelextrakt." - Joerg Gruenwald, Ph.D., PDR for Herbal Medicines (Get the book.)

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