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"Effect of Oral Zinc Supplementation on Agents of Oropharyngeal Infection in Patients Receiving Radiotherapy for Head and neck cancer. Ertekin MV; Uslu H; et al. Journal of International Medical Research; 2003 July-August, 31(4):253-266. Zinc or placebo was administered to 30 patients who were receiving radiotherapy for head and neck cancer. Findings suggested that some infections with Candida species and staphylococci were prevented by zinc supplementation. Effect of Calcium Ion Uptake on Candida Albicans Morphology. Holmes AR; Cannon RD; Shepherd MG." - Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)

"Head and neck cancer does not include brain tumors. Treatment includes radiation therapy, which is often implemented following surgery. However, radiation therapy can cause adverse, even lethal, side effects. Lethal radiation necrosis (tissue death) in the brain is one potential side effect of radiation therapy. Also, stroke rates increase by five times in people who have undergone radiation therapy for head and neck cancer. Stroke is the official cause of death among many people who have had head and neck cancer who later die after radiation therapy treatments." - Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)

"Genistein elicits pleiotropic molecular effects on head and neck cancer cells, Clin Cancer Res, 7: 4174-4181. Anderson, J. J., 1999, Plant-based diets and bone health: nutritional implications, Am J Clin Nutr, 70: 539S-542S. Anderson, R. F„ Fisher, L. J., Hara, Y., Harris, T., Mak, W. B., Melton, L. D., and Packer J.E., 2001, Green tea catechins partially protect DNA from (.)OH radical-induced strand breaks and base damage through fast chemical repair of DNA radicals, Carcinogenesis, 22: 1189-1193. Angel, P., and Karin, M." - Erich Grotewold, The Science of Flavonoids (Get the book.)

"Rich in a compound called baicalin, which has been found to be a strong inhibitor of pro-inflammatory COX and LO enzymes, this herb (in studies from the Mount Sinai School of Medicine in New York City) suppressed the synthesis and expression of inflammatory substances (including prostaglandins) in head and neck cancer cells. It also inhibited the expression of COX-2 and reduced tumor mass by 66 percent in the mice used in the study. Prostate and breast cancer cells were found to be particularly vulnerable." - Freedom Press, Natural Cancer Cures: The Definitive Guide to Using Dietary Supplements to Fight and Prevent Cancer (Get the book.)

"Zinc or placebo was administered to 30 patients who were receiving radiotherapy for head and neck cancer. Findings suggested that some infections with Candida species and staphylococci were prevented by zinc supplementation. Effect of Calcium Ion Uptake on Candida Albicans Morphology. Holmes AR; Cannon RD; Shepherd MG. Ferns Microbiology Letters, 1991 January 15, 61(2-3):187-193. Calcium was shown to inhibit the growth of Candida albicans yeast cells. Inhibition of Candida adhesion to buccal epithelial cells by an aqueous extract of Allium sativum (garlic). Ghannoum MA." - Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)

"Also, stroke rates increase by five times in people who have undergone radiation therapy for head and neck cancer. Stroke is the official cause of death among many people who have had head and neck cancer who later die after radiation therapy treatments. For this reason, cancer cure statistics can be misleading. Even though radiation therapy may cure cancer, nonrelated cancer deaths seem to be a long-term side effect to radiation. Although more people with cancer are now living beyond five years after diagnosis, premature death can be direct result of toxic therapies used to eradicate cancer." - Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)

"In yet an earlier, multicenter, double-blind, placebo-controlled trial of 540 patients with stage I or II head and neck cancer treated by radiation therapy, those who received vitamin E supplements (400 IU daily) had a higher rate of second primary cancers compared with those receiving placebo. However, upon cessation of treatment with vitamin E, these rates were lower in the group that had received supplementation vs those who had received placebo. Subjects were followed for a median of 52 months." - Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.)

"We do not recommend that people with head and neck cancer refuse radiation therapy, as it often buys years of extra life. Simply, they should take extra precautions to reduce their risk of stroke. (See under cardiovascular disease in Part Two.) Q A gene linked to the development of colon cancer (when it becomes defective and shuts off in individuals who do not seem to have a family history of the disease) has been identified by researchers at the Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University School of Medicine." - Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.) "Stroke is the official cause of death among many people who have had head and neck cancer who later die after radiation therapy treatments. For this reason, cancer cure statistics can be misleading. Even though radiation therapy may cure cancer, nonrelated cancer deaths seem to be a long-term side effect to radiation. Although more people with cancer are now living beyond five years after diagnosis, premature death can be direct result of toxic therapies used to eradicate cancer." - Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)

"Since 1950 mortality from head and neck cancer, thyroid cancer, and bladder cancer are all down.22 Although some environmental reasons may apply, my guess is that these declines are best explained by a combination of two factors: people with symptoms are seeking care earlier, and better treatment is available. Cancer testing is not a viable explanation, as no systematic testing exists for these cancers. Then there is colon and breast cancer, for which mortality is down by 25 percent and 15 percent, respectively. In both cases a systematic effort is being made to detect early disease." - H. Gilbert Welch M.D. M.P.H., Should I Be Tested for Cancer? Maybe Not and Here's Why (Get the book.)

"A randomized trial of antioxidant vitamins to prevent second primary cancers in head and neck cancer patients. J Natl Cancer Inst; 97(7):481-488. 2005 Benner SE, Winn RJ, Lippman SM et al. Regression of oral leukoplakia with alpha-tocopherol: a Community Clinical Oncology Program Chemoprevention study. J Natl Cancer Inst; 85(l):44-47. 1993 Bjelakovic G, Nagorni A, Nikolova D, et al. Meta-analysis: antioxidant supplements for primary and secondary prevention of colorectal adenoma." - Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.)

"Patients with head and neck cancer have a 60-90% 5-year survival rate, but 15-20% will develop second tumors. [Journal National Cancer Institute 97: 481-88, 2005] Vitamin E supplementation didn't significantly change this pattern. Yet the study drew wide attention in the news media. [New York Times, April 12, 2005] Recently The Cancer Treatment Centers of America sponsored a study that conclusively found antioxidant therapy does not interfere with radiation treatment. [3rd Annual Conference, Society for Integrative Oncology, Boston, Nov." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.) "Dietary Supplements: A Framework for Evaluating Safety, Institute of Medicine, National Research Council, 2004] Surprisingly, after years of condemnation by the Food & Drug Administration, a report issued at the International Conference on Head and neck cancer in 2004 by researchers at the Medical University of South Carolina indicates an extract from chaparral seems to be "completely safe as well as beneficial." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.) "In another study, patients with head and neck cancer were treated with radiation therapy and simultaneously given high-dose vitamin E. The vitamin E caused a higher rate of secondary tumors (288%), but a lower rate when vitamin E was discontinued. [Journal National Cancer Institute 97: 481-88, 2005] This is predictable. The vitamin E should not be given at the same time as radiation treatment. The problem with this type of information is that the public misconstrues what they read and mistakenly conclude that vitamin E causes cancer." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.) "Nutrition Cancer 26: 11-19, 1996] Antioxidants: Cell protectors Head and neck cancer patients who took 400 units of vitamin E for three years following radiation treatment were at greater risk for secondary tumors (288% increase) compared to patients who did not supplement with vitamin E. [Journal National Cancer Institute 97: 481-88, 2005] This increase in cancer recurrence can be explained by the provision of a sole antioxidant [just vitamin E] rather than a variety of antioxidants, and by the fact that vitamin E is not a selective anti-cancer agent." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.)

"Head and neck cancer. Available from: http://www.obgyn.net/newsrx/general_health-Head_And_Neck_Cancer-20011217-9.asp. Vitamin B-3 Responsive Diseases and Conditions PELLAGRA Prevalence Classical Pellagra Pellagra was known in Europe for near 200 years before being diagnosed in the United States, where it was first identified in 1902. It was initially described by Don Gasper Casal, a physician in the Spanish court. In 1735 Casal noted the illness among poor peasants and called it "mal de la rosa" because all affected patients had a typical reddish glossy rash on their hands and feet." - Dr. Abram Hoffer, MD, FRCP (C) and Dr. Harold D. Foster, PhD, Feel Better, Live Longer with Vitamin B-3 (Get the book.)

"Study of Accutane for reducing risk of second primary tumors in patients who have had head and neck cancer controlled by surgery and/or radiotherapy. For information: Waun Ki Hong, University of Texas, M.D. Anderson Cancer Center Division of Medicine, 1515 Holcombe Boulevard, Houston, TX 77030. Phone: 713-792-6363 (This study may be closed to new participants.) Accutane is also being tested in head and neck cancer patients by: Robert Wells Carlson, Stanford University Medical Center Division of Medical Oncology, M-2111,300 Pasteur Drive Stanford, CA 94305." - Ralph W. Moss, Ph.D., Cancer Therapy: The Independent Consumer's Guide To Non-Toxic Treatment & Prevention (Get the book.)

"This study examined the relationships of beta-carotene, vitamin A and vitamin E serum levels in head and neck cancer patients with primary tumors. Results found that patients with single head and neck cancer had lowered levels of beta-carotene and also suggest that low levels of vitamins A and E may be involved in the etiology of second tumors among such patients. —N. de Vries and G.B." - Gary Null, Ph.D., The Clinician's Handbook of Natural Healing (Get the book.) "Results of this study suggest that low serum levels of vitamin E and vitamin A are involved in the etiology of seond tumors in head and neck cancer patients. —N. de Vries and G.B. Snow, "Relationships of Vitamins A and E and Beta-carotene Serum Levels to Head and neck cancer Patients with and without Second Primary Tumors," Eur Arch Otorhinolaryngol, 247(6), 1990, p. 368-370. This review article argues that vitamin E and beta-carotene meet the criteria for an effective chemopreventive agent of oral cancer and it points to the results of eight clinical trials to support this view: —H." - Gary Null, Ph.D., The Clinician's Handbook of Natural Healing (Get the book.) "Results found that patients with single head and neck cancer had lowered levels of beta-carotene and also suggest that low levels of vitamins A and E may be involved in the etiology of second tumors among such patients. —N. de Vries and G.B. Snow, "Vitamin A, Vitamin E and Beta-carotene Serum Levels in Head and neck cancer Patients with andwithout Second Primary Tumors," Third International Head and Neck Oncology Research Conference, September 26-28, 1990, Las Vegas, NV, The American Society for Head and Neck Surgery, A3.1, 1990." - Gary Null, Ph.D., The Clinician's Handbook of Natural Healing (Get the book.) "The difference in occurrence of head and neck cancer between population with varying diets may be explained by related in vivo phenomenon. —Z. Trizna, et al., "Effects of N-acetyl-L-cysteine and Ascorbic Acid on Mutagen-induced Chromosomal Sensitivity in Patients with Head and Neck Cancers," American Journal of Surgery 162(4), October 1991, p. 294-298. Results of this placebo-controlled study found that powdered chow supplemented with 7%/wt ascorbic acid significantly reduced 1,2-dimethylhydrazine-induced tumor formation significantly in rats. —T.A. Colacchio and V.A." - Gary Null, Ph.D., The Clinician's Handbook of Natural Healing (Get the book.)

"Amifostine may also encourage the growth of bone marrow in patients with bone marrow diseases and guard against dryness of the mouth in people receiving postsurgical radiation treatment for head and neck cancer. Possible Side Effects The drug's more common side effects include nausea and vomiting (may be severe), low blood pressure, dizziness, flushing, chills, sneezing, and excessive sleepiness." - Frederic Vagnini, M.D. and Barry Fox, Ph.D., The Side Effects Bible: The Dietary Solution to Unwanted Side Effects of Common Medications (Get the book.)

"The effect of an adjuvant mistletoe treatment programme in resected head and neck cancer patients: a randomized controlled clinical trial. Eur J Cancer 37: 23-31. Stimpel M, Proksch A, Wagner H et al (1984) Macrophage activation and induction of macrophage cytotoxicity by purified polysaccharide fractions from the plant Echinacea purpurea. Infect Immunity 46: 845-849. Taylor JA, Weber W, Standish L, et al. (2003) Efficacy and safety of Echinacea in treating upper respiratory tract infections in children. JAMA 290:2824-30." - volker schulz and Rudolf Hansel, Rational Phytotherapy: A Reference Guide for Physicians and Pharmacists (Get the book.)

"The effect of an adjuvant mistletoe treatment programme in resected head and neck cancer patients: A randomised controlled clinical trial, European Journal of Cancer, 37(1): 23-31. 37. Goebell, P.J., Otto, T., Suhr, J., and Rubben, H., 2002, Evaluation of an unconventional treatment modality with mistletoe lectin to prevent recurrence of superficial bladder cancer: A randomized phase II trial, Journal of Urology, 168(1): 72-75. 38. Stumpf, C, Rosenberger, A., Rieger, S., Troger, W., and Schietzel, M." - Amarjit S. Basra, Handbook of Medicinal Plants (Get the book.)

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