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"The public hears much about the dangers of viral hepatitis infections, which can lead to liver failure. But viruses such as hepatitis A are not the leading cause of this organ's failure in the United States. Not by far. Instead, most Americans who suffer from liver failure have been poisoned by their medications. Researchers reported that 51 percent of the cases of liver failure at some two dozen American medical centers in 2003 were caused by a single drug, acetaminophen, which is sold under the brand name of Tylenol and also included in a wide array of other medicines." - Melody Petersen, Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs (Get the book.)

"Only after Audrey LaRue Jones, a 55-year-old high school teacher, died of liver failure in May 1998 did Rezulin stop being given to the volunteers in the study. Warner-Lambert maintained that Rezulin was not responsible for the liver failure that led to her death. Despite the mounting reports of liver problems in the United States, Rezulin was not withdrawn from the U.S. market until March 2000. By that time, $1.8 billion worth of the drug had been sold. The Los Angeles Times reported that, all told, Rezulin was suspected in 391 deaths and linked to 400 cases of liver failure." - John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"By 2000 half a dozen articles had appeared whose titles were blunt and pointed such as "Nefazodone-induced acute liver failure"18 and "Acute liver failure ascribed to nefazodone."19 Health Canada warned its nation's physicians that Serzone could cause liver failure in 2001. They removed the drug from the Canadian market in 2003. The Dutch Medicines Evaluation Board (CBG) announced in 2002 that because of the danger of liver failure Serzone was going to be removed from the Dutch market.20 Other European countries followed suit, but the FDA never removed Serzone from the U.S. market." - Dr. Timothy Scott, America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived (Get the book.)

"Warner-Lambert maintained that Rezulin was not responsible for the liver failure that led to her death. Despite the mounting reports of liver problems in the United States, Rezulin was not withdrawn from the U.S. market until March 2000. By that time, $1.8 billion worth of the drug had been sold. The Los Angeles Times reported that, all told, Rezulin was suspected in 391 deaths and linked to 400 cases of liver failure. Looking back on his experience, Dr. Gueriguian told the Los Angeles Times, "Either you play games or you're going to be put off limits ... a pariah." - John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"Instead, most Americans who suffer from liver failure have been poisoned by their medications. Researchers reported that 51 percent of the cases of liver failure at some two dozen American medical centers in 2003 were caused by a single drug, acetaminophen, which is sold under the brand name of Tylenol and also included in a wide array of other medicines. But dozens of other drugs can cause the liver to fail, as Jerry Houk found out. Jerry said months after he left the hospital he heard a report that Rezulin had been pulled from the market because of its propensity to ravage the liver." - Melody Petersen, Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs (Get the book.) "About 80 percent of those suffering from acute liver failure die. Weighing about three pounds, the dark reddish brown liver is the body's largest internal organ. Among its numerous functions is to act as a filter and remove harmful substances like drugs, insecticides, food additives, and other chemicals from the blood. The public hears much about the dangers of viral hepatitis infections, which can lead to liver failure. But viruses such as hepatitis A are not the leading cause of this organ's failure in the United States. Not by far." - Melody Petersen, Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs (Get the book.)

"When Rezulin, one of 11 drugs available to treat diabetes, caused 33 deaths due to liver failure, Britain, but not the US, had the good sense to ban it. All ADHD drugs now in use in the US have serious side effects not appropriately addressed by the FDA. Cylert (pemoline), found to cause liver failure and death was banned in Canada, but not the US. Strattera, a non-stimulant addition to the ADHD armamentarium was touted as non-addictive and safe until it was discovered in recent months, after being marketed, to cause liver toxicity." - Fred A. Baughman, Jr., M.D. and Craig Hovey, The ADHD Fraud: How Psychiatry Makes "Patients" of Normal Children (Get the book.)

"The Los Angeles Times reported that, all told, Rezulin was suspected in 391 deaths and linked to 400 cases of liver failure. Looking back on his experience, Dr. Gueriguian told the Los Angeles Times, "Either you play games or you're going to be put off limits ... a pariah." Another FDA medical officer and former supporter of Rezulin, Dr. Robert I. Misbin, was threatened with dismissal by the FDA. His offense?" - John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"It's a progressive autoimmune disease that leads to cirrhosis, liver failure, and death. Although xanthelasmas themselves are usually harmless, half the time they're markers of high levels of LDL cholesterol (the bad cholesterol) or low levels of HDL cholesterol (the good cholesterol), both of which are risk factors for heart disease. And because xanthelasmas can grow quite large, there's a chance they can interfere with eyesight and may need to be removed surgically. They may, however, grow back." - Joan Liebmann-Smith, Ph. D., and Jacqueline Nardi Egan, Body Signs: From Warning Signs to False Alarms...How to Be Your Own Diagnostic Detective (Get the book.)

"Health Canada warned its nation's physicians that Serzone could cause liver failure in 2001. They removed the drug from the Canadian market in 2003. The Dutch Medicines Evaluation Board (CBG) announced in 2002 that because of the danger of liver failure Serzone was going to be removed from the Dutch market.20 Other European countries followed suit, but the FDA never removed Serzone from the U.S. market. However, the antidepressant could not withstand the media reports which decimated sales and increased lawsuits." - Dr. Timothy Scott, America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived (Get the book.)

"Vitamin A is toxic in high doses for prolonged periods of time (it can cause liver failure and vaginitis) but it can be used safely with the guidance of a doctor to alleviate skin problems and even reduce heavy bleeding (it improves mucous membranes such as the uterine lining and the cervix). • Growth hormone deficiency is a plastic surgeon's dream. It causes droopy eyelids and sagging cheeks. Wrinkles deepen and a deep groove is seen in the cheeks as the skin loses its elasticity. The muscles, particularly the triceps in the back of the arms, become flaccid and hang." - Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

"The virus, which is called hepatitis B virus, can cause lifelong infection, cirrhosis (scarring) of the liver, liver cancer, liver failure and death. About 3% to 6% of the v/orld's population is currently infected with the virus and up to one-third have been exposed. Symptoms of the acute illness caused by the virus include liver inflammation, vomiting and jaundice. Vaccines currently exist for this disease. Hepatitis B virus is endemic in China and Asia. i_____i Liver cancer can have many causes. The largest risk factor is thought to be chronic hepatitis B virus infection." - Allison Tannis, Probiotic Rescue: How You can use Probiotics to Fight Cholesterol, Cancer, Superbugs, Digestive Complaints and More (Get the book.)

"In patients with severely depleted energy such as patients with advanced end-stage heart failure, liver failure, renal failure or in patients with advanced, relentless chronic fatigue syndrome there may be an advantage of using ubiquinol over ubiquinone in that the body in it's energy-starved state may appear to do better with ubiquinol since it does not need to be converted from it's oxidized form ubiquinone. This would appear to make logical sense." - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.)

"Side effects include infections, headaches, anemia, fluid retention, weight gain, and, more rarely, liver failure or cardiac events. The first of these medications was troglitazone (Rezulin). Troglitazone was found to be effective in the prevention of type 2 diabetes in at-risk patients but was associated with high rates of liver toxicity. In one trial, 7 out of 585 treated patients had liver elevations ten times that of normal levels, high enough to be potentially associated with fatal liver damage." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Researchers reported that 51 percent of the cases of liver failure at some two dozen American medical centers in 2003 were caused by a single drug, acetaminophen, which is sold under the brand name of Tylenol and also included in a wide array of other medicines. But dozens of other drugs can cause the liver to fail, as Jerry Houk found out. Jerry said months after he left the hospital he heard a report that Rezulin had been pulled from the market because of its propensity to ravage the liver. That's when he finally understood what had happened to him." - Melody Petersen, Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs (Get the book.)

"But it occurs in many patients—not just those with liver failure. When we rechecked her ammonia level after treatment, it had returned to normal. After a few months, the bacteria came back, and so did her OCD symptoms, and once again treating the bacteria cured her OCD. The link was clear. And this is just one of many ways abnormal gut bacteria can affect your thoughts and cognitive function." - Mark Hyman MD, The UltraMind Solution: Fix Your Broken Brain by Healing Your Body First (Get the book.)

"He provided a copy of a letter to members of Congress from himself and other physician colleagues at the FDA expressing concern about the FDA's failure to withdraw Rezulin from the market after the FDA had linked it to 63 deaths due to liver failure. Dr. Janet B. McGill, an endocrinologist who had participated in Warner-Lambert's early studies of Rezulin, told the Los Angeles Times that Warner-Lambert "clearly places profits before the lives of patients with diabetes." - John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"This list did include one case of liver failure, one case of hepatitis, and one case of elevated liver enzymes. These cases were related to unspecified amounts of black cohosh and unspecified products. Some studies on animals reported increased liver weights associated with very large doses over an extended period of time. Australia, Canada, and selected European countries have elected to require a warning label on black cohosh about liver effects." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"Because of the very real risk of liver failure and possible death, I would not recommend kava for the treatment of insomnia. MELATONIN Melatonin, a hormone that occurs naturally in the body, is involved in the regulation of the wake/sleep cycle. Melatonin can decrease the time it takes to fall asleep but overall has no effect on sleep time. It is popular with travelers. By taking melatonin, however, keep in mind that you are meddling with your own body's hormonal status, which can have risks. For instance, taking melatonin may affect growth or reproductive function." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.) "Because of the risk of death from liver failure, kava should not be taken. MA HUANG The Chinese plant ma huang, one of the most popular supplements, contains ephedra, a compound similar to ephedrine (see Chapter 6 for more information, page 123). Ephedra is one of the most dangerous over-the-counter supplements available today. It is associated with a two- to threefold increase in psychiatric, autonomic, heart-related, and gastrointestinal side effects. Eighty-seven episodes of heart attack, stroke, seizures, and high blood pressure have been reported to the FDA." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Acetaminophen poisoning is the number-one cause of hospital admissions for liver failure in the United States. Think what people who drink and then take Tylenol for a hangover are doing to their poor liver. Though many establishment medical types will tell you acetaminophen is "safe" in reasonable doses, I'm a hardliner on acetaminophen: If you have—or suspect you have—liver problems, the only safe dose of acetaminophen is zero. I rank it right up there with trans fats. 2. Do a periodic detoxification." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"The powerful protective effect of SNMC was demonstrated in another study of 18 patients with subacute liver failure due to viral hepatitis. Subacute liver failure is a very serious condition, typically fatal in nearly 70% of patients. However, among patients given intensive treatment with SNMC, the death rate was only 28%.10 The injectable form of licorice has been intermittently available in the United States, depending on how vigorously the Food and Drug Administration has chosen to enforce its opinion about what constitutes an "unapproved drug." - Jonathan V. Wright, M.D. and Alan R. Gaby, M.D., Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing (Get the book.)

"Longtime alcohol users, even moderate social drinkers (three or fewer glasses of alcohol a day), who ingest acetaminophen are at risk for acute liver failure. The combination of alcohol and acetaminophen taxes the liver. When acetaminophen breaks down in phase I, an extremely toxic intermediary substance emerges that should, under normal circumstances, get processed immediately in phase II. But the alcohol intake speeds up phase I and creates a backlog of this toxic intermediary." - Brenda Watson and Leonard Smith, The Detox Strategy: Vibrant Health in 5 Easy Steps (Get the book.)

"For example, when someone with late-stage liver disease develops something called "hepatic encephalopathy" or temporary insanity from liver failure, the treatment is not antipsychotics, but antibiotics to clear out the bacteria in the intestine, which produce brain-destroying toxins that can no longer be detoxified by the liver. Imagine, treating insanity with antibiotics. Similarly, we know that alcoholics become "crazy" with a condition known as Wernicke's encephalopathy from vitamin B, (or thiamine) deficiency, which can be cured by giving them a vitamin." - Mark Hyman MD, The UltraMind Solution: Fix Your Broken Brain by Healing Your Body First (Get the book.)

"Valproate can cause potentially fatal liver failure, although it very rarely does so. Lamictal, which has been shown to be helpful in cases of bipolar disorder, can cause Stevens-Johnson's syndrome, a potentially lethal disease that involves a rash that spreads over the body and causes the skin to shed. (It clears up when the medicine is stopped.) This side effect is very rare. Lithium (Eskalith, Lithobid, Lithonate), an important treatment of bipolar disorder, is a primary mineral that has been shown to stabilize the mood of patients with bipolar disorder." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"He died a horrible death from acute liver failure, bleeding out of every orifice. He left behind two kids. How do you think his physician felt? He prescribed the drug based on FDA's approval.132 In February 12, 2007 testimony before the House Subcommittee on Oversight and Investigations, FDA's Dr. David J. Graham explained the Ketek blanket approval over FDA reviewers' objections, this way: "The FDA views industry as its client, and that's the only explanation here;" "FDA saw that it needed to align its interests with the company's, and the company's interest was 'get this drug approved.'" - Jonathan W. Emord, The Rise of Tyranny (Get the book.) "Ross explains that even as late as June of 2006, after numerous cases of acute liver failure were linked to the drug, the FDA insisted on silencing internal criticism instead of acting to remove the drug from the market. "Industry has become FDA's client,"129 Ross explained. "People at FDA know they have to be careful about not upsetting industry," he said.130 Ross wrote: In the face of Congressional subpoenas and unfavorable publicity, reviewers at the FDA were warned at a June 2006 meeting by Andrew von Eschenbach, then the acting FDA commissioner, not to discuss Ketek outside the agency." - Jonathan W. Emord, The Rise of Tyranny (Get the book.)

"The possible side effects for this drug include fever, muscle aches, cramps, severe stomach pain, unusual tiredness, weakness, constipation, diarrhea, dizziness, gas, headache, heartburn, nausea, skin rash, minor stomach pain, birth defects, allergic reactions, "unwanted effects" in nursing babies, liver failure and, when taken "in conflict" with ten listed medications, may result in kidney failure and muscle problems.109 There is at least one case study that suggests that Lipitor can cause severe mental problems.110 Plavix is used to prevent stroke and plaque buildup on artery walls." - Kenneth W Thomas, Ron Gilbert, Gerd Schaller, Side Effects: The Hidden Agenda of the Pharmaceutical Drug Cartel (Get the book.)

"Frustrated by FDA's refusal to remove the drug from the market and fearing that through inaction he would countenance deaths, Misbin wrote to a member of Congress pleading for legislative intervention to stop the marketing of the drug (stating in his letter, "I am writing to enlist your aid in convincing my superiors at FDA that Rezulin should be removed from the market because of its unacceptably high risk of causing liver failure"92). The agency censored a scientific paper by Misbin that revealed the liver toxicity of Rezulin, denying him the right to publish it in a medical journal. " - Jonathan W. Emord, The Rise of Tyranny (Get the book.)

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