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"This type of lipoic acid is chemically identical to the one found in nature, and it accounts for half of the alpha-lipoic acid molecule. R-lipoic acid is more expensive than alpha-lipoic acid, but it has more biological activity. As an alternative to alpha-lipoic acid, try 100 mg a few minutes before meals. • Chromium. Chromium is an essential mineral that plays a central role in normal insulin function and the burning of blood sugar. The two leading forms of this mineral are chromium polynicotinate and chromium picolinate, and both forms have been extensively tested in people."
- Jack Challem, Stop Prediabetes Now: The Ultimate Plan to Lose Weight and Prevent Diabetes (Get the book.)

"An antioxidant itself, alpha-lipoic acid is able to recharge other antioxidants such as vitamin C and glutathione. lipoic acid, like thiamin and biotin, contains sulfur. Alpha-lipoic acid is approved for the treatment of diabetic neuropathy and is available by prescription in Germany. BIOFLAVONOIDS Bioflavonoids (or just flavonoids) have been referred to as vitamin P. Bioflavonoids are not vitamins and are not essential for life. Bioflavonoids are excellent antioxidants found in many plant foods. As potent antioxidants, they protect us from arterial damage and cancer formation."
- Dr. Steve Blake, Vitamins and Minerals Demystified (Get the book.)

"Alpha-lipoic acid is a biological antioxidant; it prevents HIV activation, and reacts with reactive oxygen 44 species. • lipoic acid prevents gene expression of HIV virus.45 • Of all the compounds tested, thiamine disulfide, alpha-lipoic acid, and N-acetylcysteine significantly depressed HIV-1 Tat activity.46 • The inhibitory action of alpha-lipoic acid was found to be very potent as only 4 mM was needed for a complete inhibition, whereas 20 mM was required for N-acetylcysteine. These results indicate that alpha-lipoic acid may be effective in AIDS therapeutics."
- Michael T. Murray, ND, Textbook of Natural Medicine 2nd Edition Volume 2
(Get the book.)

"ALPHA lipoic acid (ALA) One of the most important antioxidants, although we need a variety of them, is alpha lipoic acid. ALA helps with a variety of problems, one of which is the cardiovascular complications of diabetes having to do with small-vessel damage from inflammation. We also use a proteolytic enzyme called Vitalzym X to neutralize and reverse this inflammatory process. Vitamin E also seems to play a role at 1,200 IU per day in creating a reduction in LDL oxidation."
- Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.)

"Alpha lipoic acid?00 mg Sometimes called the "Mother" antioxidant, alpha lipoic acid (ALA) plays a major role in helping recycle vitamins E and C so that they can be used over and over again by your body. In its own right, ALA is one of the main boosters of glutathione levels in body cells, and is one of the key co-factors involved in generating energy in the cells mitochondria. And finally, ALA has also been shown to significantly rejuvenate the cognitive skills of people as they age. • SOD?"
- Jon Barron, Lessons from The Miracle Doctors: A Step-by-Step Guide to Optimum Health and Relief from Catastrophic Illness (Get the book.)

"Effect of Alpha lipoic acid on Intracerebroventricular Streptozotocin Model of Cognitive Impairment in Rats. Sharma M; Gupta YK. European Neuropsy-chopharmacology, 2003 August, 13(4):241-247. This study concluded that alpha lipoic acid in effective in preventing cognitive impairment and oxidative stress. Ginkgo Biloba Extract Egb 761 in Dementia: Intent-To-Treat Analyses of a 24-Week, Multi-Center, Double-Blind, Placebo-Controlled, Randomized Trial. Kanowski S; Hoerr R. Pharmacopsychiatry, 2003 November, 36(6):297-303."
- Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)

"Lipoic acid is an excellent antioxidant for the nervous system; thus, it is helpful for the nerve pain and nerve inflammation of fibromyalgia.669,670 lipoic acid is a primary nutrient to help stop the progression of tissue damage. The most effective form of lipoic acid for supplementation is called R alpha lipoic acid. There is also hope for repairing tissue damage that has already been done. We use the enzymes bromelain and papain to help dissolve abnormal tissue protein damage."
- Byron J. Richards, CCN, Mastering Leptin: The Leptin Diet, Solving Obesity and Preventing Disease, Second Edition (Get the book.)

"New Antioxidant Discovery Alpha lipoic acid is a chemical that the body naturally produces, and it is a powerful antioxidant. Not only does the acid prevent the degeneration of cells, it also boosts the antioxidant power of vitamins C and E. You can find alpha lipoic acid at health food stores. Follow package instructions for appropriate dosages and be sure to consult with your doctor. Sweat as Anti-Aging Medicine A long-awaited verdict is in: Exercise doesn't just help you feel better; it measurably slows down the aging process. After studying 20 exercising men for more than 20 years. Dr."
- Bottom Line Books, Uncommon Cures For Everyday Ailments (Get the book.)

"ALPHA LIPOIC ACID Alpha lipoic acid (ALA) (sold as Juvenon, or as ALA, from a number of supplement makers) is found in liver, potatoes, and broccoli. It is also naturally found in the body and can be synthesized in the brain. ALA is a natural cofactor for a number of enzyme complexes involved in energy transfer. It is promoted in the U.S. as an antioxidant that can help prevent everything from cancer to heart disease, and is prescribed as a supplement for diabetic neuropathy in Germany."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"This form of lipoic acid may actually yield greater benefits than alpha-lipoic acid in lowering blood sugar and improving insulin activity. The problem is that it is considerably more expensive than alpha-lipoic acid (which contains 50 percent of the R-lipoic form). Take 100 to 200 mg a few minutes before each meal. • Chromium. Symptoms of chromium deficiency—increased glucose, insulin, total cholesterol, and triglycerides—resemble those of prediabetes."
- Jack Challem, Stop Prediabetes Now: The Ultimate Plan to Lose Weight and Prevent Diabetes (Get the book.)

"I only know it's in there Alpha lipoic acid somewhere because a blood test—and subsequent liver biopsy taken back in the mid-90s—tells me so. The universe willing, I expect to live a long, healthy life and die of old age. My hepatitis C can come along with me seie for the ride if it likes. Okay, maybe this sounds flippant. But my experi- might even keep you symptom-free. At the very ence has given me great optimism when it comes least, it will help your liver. to dealing with hepatitis C in a "natural" way."
- Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Rosa Mosqueta Night Creme with Alpha lipoic acid ($21.50for 1 ounce) contains a tiny amount of alpha lipoic acid (listed as such, though it should be listed as thioctic acid). But even if it was brimming with it, or other antioxidants, the translucent glass bottle won't hold them stable. This is a decent moisturizer for dry to very dry skin and, thankfully, lacks any of the problematic plant extracts found in most of Aubrey Organics' moisturizers. The amount of grain alcohol is too small to cause irritation. © Rosa Mosqueta Rose Hip Seed Oil ($12.98 for 0."
- Paula Begoun and Bryan Barron, Don't Go to the Cosmetics Counter Without Me, 7th Edition (Get the book.)

"Among these are: pycnogenol, which is a water extract from the bark of the French maritime pine; grape seed extract; tocotrienols; vitamin C ester; alpha lipoic acid; dmae; and alpha and beta hydroxy acids. On the other hand, a poor diet, processed foods, cured meats, tobacco smoke, infections, alcohol, stress, air pollution, pesticides, and radiation all promote oxidation in the human body. Even if we are minimizing the effects of the aforementioned free radical developers, given our modern urban, industrialized, and technological lifestyles, we cannot completely avoid them."
- Ron Garner, Conscious Health: A Complete Guide to Wellness Through Natural Means (Get the book.)

"Alpha lipoic acid has no effect on glucose levels, but one study has shown it to decrease pain in patients with diabetic neuropathy. ALA does not have known major toxicities. CHROMIUM Chromium is an essential metal whose exact mechanism of action is unknown. Chromium is present in foods, and although the prevalence of chromium deficiency in humans is unknown, it is thought to be rare. Based on animal studies of chromium deficiency showing the development of insulin resistance, chromium has been advocated as a supplement for the treatment of diabetes."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"In reactivating these antioxidants, both niacin and lipoic acid may play a role. Vitamin E has the potential to act as a free radical rather than as an antioxidant when co-antioxidants such as vitamin C are not available. /— / Repaired \ \ Molecule/ Vitamin E neutralizes the free radical Vitamin E becomes oxidized Vitamin C regenerates vitamin E Vitamin C becomes oxidized Glutathione or niacin as NADH Vitamin C is regenerated by glutathione or niacin Figure 5-5 Regeneration of vitamin E with vitamin C and glutathione or niacin."
- Dr. Steve Blake, Vitamins and Minerals Demystified (Get the book.)

"ALA Alpha lipoic acid (ALA), which is found in liver, potatoes, and broccoli, has no effect on glucose levels. It is, however, prescribed in Germany for diabetic neuropathy. In a three-week German study, 328 patients with type 2 diabetes and diabetic neuropathy received either intravenous ALA or a placebo. The study found a statistically significant improvement in the pain, tingling, and disability related to neuropathy in those who got the ALA."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Lipid peroxidation, which is free radical oxidation of the lipids, is increased in diabetic neuropathy and neutralized by alpha lipoic acid. ALA also tends to prevent protein glycosylation oxidation, because it acts as an antioxidant and stimulates glucose uptake by the cells. ALA is actually approved for the treatment of diabetes in Germany for diabetic neuropathy. A high dose, about 600 mg per day, is needed to improve diabetic neuropathy.131 ALA's primary effect is its antioxidant reaction."
- Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.)

"There is some suggestion that lipoic acid reactivates vitamins C and E when they have performed their antioxidant function, and works synergistically with niacin and thiamine, as well. GAMMA LINOLENIC ACID (GLA) GLA reportedly can reverse nerve damage to peripheral nerves in patients with diabetic neuropathy. GLA regulates insulin, and seems to protect against diabetic heart, eye, and kidney damage. GLA has an insulin-sparing activity that allows insulin to be more effective. Diets that are relatively high in linoleic acid appear to decrease the progression of microangiopathy in diabetics."

- Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.)

"When using lipoic acid for diabetic neuropathy, improvement is usually apparent within three to six weeks. Coenzyme Q10 Coenzyme Q10 (CoQlO) is a fat-soluble, vitamin-like nutrient that is produced by the body and is present in every cell. This nutrient plays a critical role in energy production and also acts as a potent antioxidant. Levels of CoQl 0 decline with age and are also low in people who have diabetes and other chronic conditions, including heart disease and cancer."
- Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci USA 2002; 99(4): 1870-75. Halat KM, Dennehy CE. Botanicals and dietary supplements in diabetic peripheral neuropathy. J Am Board Fam Pract 2003 Jan-Feb; 16(l):47-57. Hall WL et al. Casein and whey exert different effects on plasma amino acid profiles, gastrointestinal hormone secretion and appetite. Br Nutr 2003 Feb; 89(2):239-48. Hama T et al. Intestinal absorption of beta-alanine, anserine and carnosine in rats."

- Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"Oral treatment with alpha lipoic acid improves symptomatic diabetic polyneuropathy: The SYDNEY 2 trial. Diabetes Care 2006 Nov; 29(11):2365-70. CHAPTER 9 Clouse RE, Lustman PJ. Depression and coronary heart disease in women with diabetes. Psychosom Med 2003 May-Jun; 65(3):376-83. DeRubeis RJ et al. Cognitive therapy vs medications in the treatment of moderate to severe depression. Arch Gen Psychiatry 2005 Apr; 62(4):409-l6. Eren I et al. The effect of depression on quality of life of patients with type II diabetes mellitus. Depress Anxiety 2007 Feb 20. Feldman G."

- Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"University of California for more than 40 years and author of The Antioxidant Miracle, has called alpha lipoic acid "probably the most potent naturally occurring antioxidant known to man." By the time you read this, selenium's reputation will probably be even greater than it is today, and it's already held in pretty high esteem."
- Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Antioxidants: vitamin C, lipoic acid, (Bilel green tea, NAC, fruits and vegetables.) Quinones • Cancer Urine Stool So you have learned a bit about the good and bad estrones. Now it's time to look at how you can improve your estrones, which are made in many of your cells, particularly your liver. Most estrogen metabolism takes place in the liver. It is amazing to me that Chinese medicine thousands of years ago appreciated liver metabolism and how to keep hormones safe. The Chinese understood that many women's health problems improved when the health of their liver improved."
- Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

"Alpha lipoic acid has such a profound effect, says Mullin, because it penetrates into the central nervous system, offering protection from the kind of free-radical damage that is often seen in multiple sclerosis and other neurological autoimmune diseases. Again, work carefully with your doctor and/or nutritionist. Just because a supplement or vitamin is rich in antioxidants doesn't mean gobbling handfuls of it will be at all useful or prudent. Research on antioxidants and autoimmune disease is still new—as is research into antioxidants in general."
- Donna Jackson Nakazawa, The Autoimmune Epidemic (Get the book.)

"Chelation can exacerbate these problems, especially if iV-acetyl-cysteine or alpha lipoic acid are taken orally during the chelation process. These conditions can generally be resolved with nutritional therapy, supplementation therapy, and medication. It is important to clear up these problems before beginning chelation. Sometimes, when these problems linger, it can be frustrating to have to postpone chelation, since chelation can be so valuable. Even so, it's important to do things in the right order. The timing of the Healing Program can be of critical significance."
- Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.)

"They also include the use of alpha lipoic acid, which can act as a mild chelator, and TTFD, another sulfur-containing substance that can help detoxify heavy metals, especially arsenic. If your physician does choose to use one of these other methods, or to combine several, that choice, when applied and monitored appropriately, is within the realm of responsible integrative medicine. Sometimes different patients respond more positively to one chelating agent than another, and your child's own physician will be in the best position to recommend the most appropriate medication."

- Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.)

"Another substance with mild chelating properties is alpha lipoic acid, or ALA. This natural chelator is much less efficient than others, however, so it is not generally applied as a first-line tactic against heavy metals. One advantage of ALA is that it regenerates glutathione, which helps drive the natural detoxification processes of methylation and glutathione conjugation. Another advantage is that it's a powerful antioxidant, and can therefore help fight inflammation, at the same time that it is helping to excrete heavy metals."

- Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.)

"Because diet alone may not suffice, I usually recommend rotating antioxidants. lipoic acid (100 mg twice daily), green tea extract, vitamin C (1,000 to 2,000 mg/day) and NAC (N-acetylcysteine, 1,000 to 1,500 mg/day) are some of the ones I recommend. Choose a bottle or two and take it for a month or so, then switch. In addition to supporting antioxidant levels, our cytochrome P450 (the part of our liver where Phase 1 takes place) needs minerals such as iron, magnesium, selenium, and other trace minerals, as well as B vitamins, particularly riboflavin and niacin."
- Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

"Rotate antioxidants (use a bottle of one or two, and vary throughout the year) such as lipoic acid (200 mg/day), coenzyme Q10 (100 to 200 mg/day), vitamin C (1,000 to 2,000 mg/day), green tea extract, and NAC (N-acetylcysteine) (1,000 to 1,500 mg/day). Ensure that you are taking enough magnesium and B vitamins, particularly B6, B12, and folic acid. Request genetic testing to see if you have inherited problems breaking down estrogen, or problems with inflammation, clotting, or bone loss. Certain vitamins can be given to improve inherited metabolic problems."

- Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

"Selenium 200 meg daily • lipoic acid 100 to 300 mg/day • Vitamin C 1,000 to 2,000 mg/day • Green tea extract (Doses vary with extract strength, usually 1 to 2 capsules daily.) • NAC (N-acetylcysteine) 500 to 1500 mg/day (N-acetylcysteine is used to raise glutathione levels naturally. Glutathione is important for detoxifying dangerous substances in our liver. Glutathione is not absorbed from the digestive tract, so NAC is one of the only ways to raise glutathione inside the body safely. NAC is used to counter the effects of heavy metals and other toxins from pollution and chemical exposures."

- Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

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