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"Increased insulin sensitivity leading to better blood-sugar control. 2. Reduced insulinlike growth factor-1 (IGF-I) levels—a molecule related to a growth hormone that promotes cancer growth. 3. Increased AMP-activated protein kinase (AMPK)—a signaling system in the body that controls insulin sensitivity and can prevent diabetes. 4. Increased peroxisome proliferator-activated receptor—coactivator 1 (PGC-1) activity—which is a critical signaling system that turns on genes that improves blood-sugar control and improves mitochondrial function. 5."
- Mark Hyman MD, The UltraMind Solution: Fix Your Broken Brain by Healing Your Body First (Get the book.)

"It increases insulin sensitivity through dietary change and exercise. The increased insulin sensitivity allows for the emergence of a desired weight more appropriate to caloric intake. It also minimizes negative physical symptoms associated with low blood sugar. The dietary plan enhances serotonin production by increasing the availability of the serotonin precursor tryptophan through the use of sequential, timed consumption of proteins and carbohydrates."
- Kathleen DesMaisons, Potatoes Not Prozac: Solutions for Sugar Sensitivity (Get the book.)

"We know from animal studies that soy protein can reduce body fat accumulation and improve insulin sensitivity.45 There's yet one more emerging area of study on soy that points to the possibility that it could play a role in promoting weight loss. In a study of rats, researchers found that soy isoflavones actually played a role in reducing inflammation, a condition that we've looked at as playing a role in exacerbating obesity and weight gain. The rats in this study that consumed soy isoflavones had improved insulin sensitivity, which seemed to be caused by a reduction in inflammation."
- Wendy Bazilian, DRPH, MA, RD, Steven Pratt, MD, Kathy Matthews, Superfoods Rx Diet: Lose Weight with the Power of SuperNutrients (Get the book.)

"It seems to improve insulin sensitivity and insulin secretion. For diabetics using insulin, the use of insulin therapy causes the loss of potassium. High potassium reduces the risk of heart disease, and lowers high blood pressure. A number of studies indicate that groups with relatively high dietary potassium intakes have lower blood pressures than comparable groups with relatively low potassium intakes."
- Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.)

"But nonetheless, the fact remains that insulin sensitivity is often improved with simple administration of this easy-to-find mineral, and it assists many diabetics in achieving better glucose control. So why miss a chance to take such an easy step for health protection? Even though we've yet to lock in a working explanation, there is a hypothesis for those of you who like to know pending theories on how things work. Tyrosine kinase is an enzyme that can affect carbohydrate metabolism."
- Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.)

"In the animal model, adequate magnesium intake supports insulin sensitivity as well as glucose metabolism. Postmenopausal women were a subpopulation in a recent investigation that correlated magnesium deficits with an increase in abdominal girth, one of the physical hallmarks of insulin resistance. The postmenopausal women were especially affected—just ask my now postmenopausal wife, and she'll tell you that the battle of the belly-bulge is her number one issue!"

- Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.)

"The combination diet caused a 50 percent improvement in insulin sensitivity. In a separate study looking at the effect the DASH diet had on metabolic syndrome symptoms in Iranian men and women, Dr. Leila Asadbakht saw reduced waist circumferences and body weight. In fact, the DASH diet worked better than a calorie-restricted diet. And compared to the calorie-restricted diet, the DASH diet significantly lowered triglycerides and raised HDL, and it lowered fasting blood sugar more efficiently."
- James Dowd and Diane Stafford, The Vitamin D Cure (Get the book.)

"Vitamin D improves insulin sensitivity, and this serves muscles well during exercise. You need vitamin D to breathe well. Researchers measured how much air you can blow out in one second and the total amount of air you can blow out period, and they found that both were significantly higher in people with the highest vitamin D levels compared to those with the lowest levels. The differences were greatest in people sixty or older. The difference due to vitamin D was also greater than the difference due to smoking."

- James Dowd and Diane Stafford, The Vitamin D Cure (Get the book.)

"Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons. Am J Clin Nutr. 2005 Mar;81(3):611-614. Heinrich U, Neukam K, Tronnier H, Sies H, Wilhelm S. Long-term ingestion of high flavanol cocoa provides photoprotection against UV-induced erythema and improves skin condition in women. Journal of Nutrition. 2006;136:1-5. Noe V et al. Epicatechin and a cocoa polyphenolic extract modulate gene expression in human Caco-2 cells. J Nutr. 2004 Oct;134(10):2509-2516."
- David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"Effect of whole grains on insulin sensitivity in overweight hyper-insulinemic adults. Nutr Cancer. 1998;30(2):85-96. Whey www.wheyoflife.org; www.wheyprotein.com Agin D, et al. Effects of whey protein and resistance exercise on body composition and muscle strength in women with HIV infection. AIDS. 2001 Dec 7; 15(18): 2431-2440. Aoe S et al. A controlled trial of the effect of milk basic protein (MBP) supplementation on bone metabolism in healthy menopausal women. Osteoporos Int. 2005 Dec;16(12):2123-2128. Aoe S et al."

- David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"For example, in a recent randomized, double-blind, placebo-controlled trial of sixty-three type 2 diabetics with decreased magnesium blood levels, oral supplementation improved both insulin sensitivity and metabolic glucose control. Now, how much easier could a "medical intervention" be than taking magnesium? Multiple studies have also associated magnesium intake with diabetes risk. Despite the fact that a couple of studies provided evidence to the contrary, it's considered an established fact that low serum levels of magnesium are associated with a risk for developing diabetes."
- Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.)

"Monunsaturated fats, such as those in olive oil, almonds, and avocados, improve insulin sensitivity.63 A Harvard study in 2002 on the benefits of nuts concluded that high dietary nut consumption decreased the risk of sudden cardiac death, a leading cause of death among diabetics. Nuts and seeds are also high in plant sterols (phytosterols), which decrease cholesterol and improve heart health.64'65 In the intestinal lumen, phytosterols displace cholesterol and inhibit cholesterol absorption."
- Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.)

"A high whey protein diet reduces body weight gain and alters insulin sensitivity relative to red meat in Wistar rats. / Nutr. 2004; 134:1454-1458. Bounous G. Whey protein concentrate (WPC) and glutathione modulation in cancer treatment. Anticancer Research. 2000;20:4785-4792. Bounous G et al. Immunoenhancing property of dietary whey protein in mice: role of glutathione. Clinical Investigative Medicine. 1989; 12:154-161. Eason R, Badger T et al."
- David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"We call this condition insulin resistance; its opposite is insulin sensitivity, which is what you want. Research demonstrates that vinegar makes the cells more "sensitive" to insulin, a desirable effect indeed. This makes apple cider vinegar a powerful natural weapon, along with cinnamon and chromium, in the fight to control blood sugar and help get carbohydrate metabolism on track. Respected nutritional researcher Jeff Volek, Ph.D., R.D., suggests a salad with vinegar at the beginning of every meal for its potential in managing blood sugar."
- Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"The plasma magnesium level has been shown to be inversely related to insulin sensitivity. Magnesium supplementation improves insulin sensitivity as well as insulin secretion in patients with type 2 diabetes. Nevertheless, no beneficial effects of oral magnesium supplementation has been demonstrated on glycaemic control either in patients with diabetes type 1 or 2. Oral magnesium supplementation reduced the development of type 2 diabetes in predisposed rats."
- Mark Sircus, Transdermal Magnesium Therapy (Get the book.)

"If you focus on enhancing beta-cell function, increasing insulin sensitivity, and controlling glycation, you can dramatically change the course of type 2 diabetes or even prevent it altogether. DIABETES: THE BASICS Diabetes is, unfortunately, a relatively common disease, and many people either know someone who has the condition or have it themselves. Therefore, it's easy to fall into the trap of thinking diabetes "isn't a big deal." I actually overheard someone express that very sentiment during a recent scientific conference."
- Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"Being overweight or obese also is a contributing factor, because excess fat impairs insulin sensitivity. Insufficient exercise also reduces the ability of muscles to use insulin. Many people who have insulin resistance and high blood sugar have at least one or more of the following conditions: high triglyceride levels (a type of fat in the blood), high blood pressure, low high-density lipoprotein (HDL) blood levels (the "good" cholesterol), and/or excess abdominal girth (a "beer belly"). This combination of conditions is known collectively as metabolic syndrome or insulin resistance syndrome."

- Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"These are just some of the things you'll notice, because behind the scenes, your diet will be having a positive impact on beta-cell function, insulin sensitivity, and the expression of genes involved in glucose metabolism. CHOOSE GLYCOTOXIN-FREE FOODS When we first introduced the idea of glycation in chapter 1, we noted that elevated blood sugar levels as well as the food you eat contribute to this damaging process. Food-derived glycotoxins do their damage in several ways."

- Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"Exercise causes GLUT-4 transporters to rise to the surface of the cellular membrane, where they can shuttle circulating glucose into the cell, increasing insulin sensitivity and decreasing insulin needs. Findings from the Nurses' Health Study and Health Professionals Follow-Up Study suggest that walking briskly for a half hour every day reduces the risk of developing Type-2 diabetes by 30 percent. The benefits of exercise, with suggestions and data, will be presented at greater length in Chapter 3. Television Programming Let's look at television watching specifically."
- Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.)

"They may also increase levels of high-density lipoprotein (HDL, or "good") cholesterol, reduce blood pressure, and improve insulin sensitivity when part of a reduced-carbohydrate diet. Most experts advise aiming for 10 to 15 percent of calories from monounsaturated fats (for a 2,000-calorie diet, 15 percent computes to 33 grams of monounsaturated fat per day)."
- Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)

"Decreased insulin sensitivity and liver toxicity can result from daily amounts over 2000 mg. However, niacin in the form of nicotinic acid can cause "niacin flush" in amounts as low as 35 mg. Nicotinic acid can dilate the capillaries, causing a brief tingling and flushing of the skin. Summary for Niacin—Vitamin B3 Main function: energy metabolism. RDA: men, 16 mg; women, 14 mg (niacin equivalent). No toxicity has been reported from food; flushing has been reported above 35 mg in the nicotinic acid form; no effects have been noted below 2000 mg of niacinamide. Deficiency disease: pellagra."
- Dr. Steve Blake, Vitamins and Minerals Demystified (Get the book.)

"The hallmarks are the abnormal accumulation of body fat resulting in central obesity, decreased insulin sensitivity leading to adult-onset diabetes, and abnormalities in blood lipids associated with high blood cholesterol. The full-blown extremes of the Metabolic Syndrome is the kiss of death in terms of the 25 percent of the hazard to your longevity that can be ascribed to biological proximate causes; it is atherogenic and diabetogenic, thereby predisposing to hypertension, heart attacks, renal failure, strokes, and other portals for leaving this life."
- Nortin M. Hadler MD, Worried Sick: A Prescription for Health in an Overtreated America (Get the book.)

"Earlier I mentioned some "hard-core" research, and here it is: A recent study in Diabetes Care demonstrated that apple cider vinegar improved insulin sensitivity in insulin-resistant subjects. Let me tell you how important this is: If you've read my other books—especially Living the Low Carb Life—you remember that insulin is an important hormone with multiple purposes that's made by the pancreas. Your body releases insulin when blood sugar goes up, as it does when you eat food, especially carbohydrates."
- Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"DHEA does not have effects on measures of body composition affected by aging, like muscle strength, insulin sensitivity, and oxygen consumption or on quality of life.22 Studies have shown that DHEA improves feelings of well-being and is useful in the treatment of depression. However, DHEA does not work better than antidepressants. I do not recommend DHEA for the treatment of depression or for any other indication."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Nettle root • Green tea • Soy • Flaxseed Other herbs and nutrients can improve insulin sensitivity and PCOS: • Chromium • Fenugreek powder • Vitamin C • Bitter melon Licorice can lower serum testosterone in women and saw palmetto can inhibit the conversion of testosterone to dihydrotestosterone (a stronger form of testosterone). By inhibiting this conversion, we am maybe modestly decrease testosterone-induced hair loss and acne."
- Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"Finally, exercise reduces the risk of arrhythmias, normalizes blood lipids, and increases insulin sensitivity. A recent study suggests that exercise and modest diet changes can decrease cholesterol and resultant atherosclerosis comparable to certain statins. Most important, by staying active with moderate levels of physical activity, we can prevent cardiovascular disease independent of other risk factors and improve our life expectancy."

- Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"The rats in this study that consumed soy isoflavones had improved insulin sensitivity, which seemed to be caused by a reduction in inflammation.41' f you're a postmenopausal woman who has metabolic syndrome, you could benefit from regular consumption of soy nuts. In a study published in the American Journal of Clinical Nutrition, postmenopausal women diagnosed with metabolic syndrome, also called Syndrome X, who ate soy nuts over a period of 8 weeks enjoyed better glycemic control and better lipid profiles when compared to a control group.4"
- Wendy Bazilian, DRPH, MA, RD, Steven Pratt, MD, Kathy Matthews, Superfoods Rx Diet: Lose Weight with the Power of SuperNutrients (Get the book.)

"The reviewers also reported that vegetarians experienced increased insulin sensitivity, meaning their cells absorbed nutrients more easily. Part-time vegetarians reap health benefits. There's not a great deal of research on part-time vegetarians, but in my opinion, eating vegetarian more often and being carnivorous less often offers a number of distinct benefits. In one Swedish study, healthy semivegetarian or lacto-vegetarian women had a lower risk of overweight and obesity than did omnivorous women. There's one of the most prized benefits right there!"
- Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)

"If you have a little more time to exercise or if you would like a change of pace, we also discuss other types of physical activities that are beneficial for improving insulin sensitivity and blood glucose control and how and when to monitor your blood glucose around your exercise sessions. PHYSICAL ACTIVITY AND DIABETES Physical activity has far-reaching effects and benefits for everyone. This is especially true for people who want to prevent, reverse, or better manage metabolic disease."
- Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"They may also increase high-density lipoprotein (HDL, or "good") cholesterol levels, reduce blood pressure, and improve insulin sensitivity. Good sources include olive oil, canola oil, peanut oil, avocados, and some nuts, such as almonds. Omega-3 fatty acids, on the other hand, especially those found in fish, may reduce the risk of blood clots, lower triglyceride levels, and promote normal blood pressure. There's also some evidence that omega-3s may lower heart disease risk, and scientists continue to study their role in reducing cancer risk."
- Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)

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