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"Premixed (combined short- and intermediate-acting): begins in thirty minutes and works for sixteen to twenty-four hours The seventh type is inhaled insulin, which generally consists of a powdered formulation that you inhale into your lungs. inhaled insulin is formulated in such a way as to optimize pulmonary (lung) delivery and absorption. Inhaled insulin is not for everyone. If you have asthma, bronchitis, emphysema, or if you smoke or recently quit smoking (within six months), you should not use this drug." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.) "Furthermore, if you currently need injectable insulin, inhaled insulin can be used at mealtime, but not as a replacement for your longer-acting injections. Although we are enthusiastic about the mealtime convenience of inhaled insulin, there remain residual, open-ended questions about the possible long-term effects this type of insulin delivery system may have on the lungs. Diabetes Medication Combinations Many people with diabetes are taking more than one antidiabetes medication or are taking one of the newer combination drugs." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"Exubera is also unlikely to be the only inhaled insulin on the market for long. Eli Lilly and Co., Kos Pharmaceuticals Inc., MannKind Corp. and Novo Nordisk A/S all are developing their own versions. Inhaled Insulin Has Drawbacks Exubera requires carrying a device the size of a flashlight, plus foil-wrapped insulin packets. Insulin shots are less cumbersome, quicker and virtually painless. Other drawbacks: Long-term effects on the lungs are unknown...inhaled insulin often still requires a patient to take one or two injections of long-acting insulin each day.. ." - Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.)

"Although we are enthusiastic about the mealtime convenience of inhaled insulin, there remain residual, open-ended questions about the possible long-term effects this type of insulin delivery system may have on the lungs. Diabetes Medication Combinations Many people with diabetes are taking more than one antidiabetes medication or are taking one of the newer combination drugs. Sulfonylureas are sometimes taken along with metformin or TZDs for improved glycemic control, while TZDs are taken with metformin for improved glycemic control, insulin sensitivity, and beta-cell health." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"Data on the first inhaled insulin product, Exubera (produced by a partnership between Pfizer of the US, Sanofi-Aventis of Europe and drug delivery company Nektar Therapeutics), was submitted in the US in March 2005. Whatever happens in the marketplace, however, doesn't detract from the fact that perfect insulin delivery is not an easy goal. Companies compete for benefits that become increasingly marginal. Most of the novel insulins in development are appealing because they act fast. But it is thought most patients will still need a conventional long-acting insulin injection in the morning. " - Jacky Law, Big Pharma: Exposing the Global Healthcare Agenda (Get the book.)

"Other drawbacks: Long-term effects on the lungs are unknown...inhaled insulin often still requires a patient to take one or two injections of long-acting insulin each day.. .insurance coverage is uncertain. Anne Peters, MD, professor of clinical medicine, Keck School of Medicine, University of Southern California, Los Angeles. Double Trouble— Up to 30% May Have Both Type land 2 Francine Kaufman, MD, pediatric endocrinologist, head of the Center for Diabetes and Endocrinology, Children's Hospital, Los Angeles, and past president, American Diabetes Association." - Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.) "US Food and Drug Administration (FDA), allowing millions of type 1 and type 2 diabetics the option of avoiding countless daily injections. A NEW OPTION Exubera is insulin that has been formulated into a dry powder that is inhaled into the lungs using a small, hand-held device. Like injected insulin, Exubera is administered before meals. "This is the first new insulin delivery option introduced since the discovery of this drug in the 1920s," says Dr. Steve Galson, director of the FDA's Center for Drug Evaluation and Research. " - Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.)

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