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NaturalPedia > Hormones and Biochemistry > Homocysteine
Quotes about Homocysteine from the world's top natural health / natural living authors
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"The use of B vitamins has also been advocated as a way to improve cognition because high levels of the amino acid homocysteine have been seen in patients with Alzheimer's disease. Since homocysteine is involved in vitamin B pathways, it was felt that lowering homocysteine with vitamin B therapy would lead to an improvement in cognition. In one study, 276 healthy people over age sixty-five with elevated homocysteine concentrations were given folate and vitamins B12 and B6 or a placebo. Neither folate nor vitamin B supplementation resulted in an improvement in scores of cognition after two years." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)
| "Folic acid, vitamin B6, and vitamin B12 all can reduce levels of homocysteine.
Pregnant women have a special need for folic acid because it's key to fetal development and nervous system functioning. The same goes for women who are planning pregnancies.
Vitamins B3 (Niacin), B6, B12
Niacin and vitamins B6 and B12 help to prevent cardiovascular disease by lowering homocysteine levels and raising HDL (good) cholesterol. They are also important for nervous system functioning.
These vitamins are most abundant in lean, fresh animal meats, including seafood." - James Dowd and Diane Stafford, The Vitamin D Cure (Get the book.)
| "Homocysteine
Homocysteine is an amino acid that is formed when your body metabolizes or processes methionine (an amino acid that's part of protein foods). homocysteine is toxic, and normally a healthy body breaks it down before it can build up. To keep homocysteine levels low, you need B vitamins, especially vitamin Bj2 and folic acid. homocysteine levels rise when you're nutritionally deficient and don't get enough B vitamins, or enough choline and betaine, important factors that help B vitamins perform their functions." - Marc R. Rose, Michael R. Rose, Save Your Sight! Natural Ways to Prevent and Reverse Macular Degeneration (Get the book.)
| "Homocysteine causes behavioral deficits, and melatonin may protect against homocysteine toxicity.
The Effect of Vitamin-Mineral Supplementation on the Intelligence of American Schoolchildren: A Randomized, Double-Blind Placebo-Controlled Trial. Schoenthaler SJ; Bier ID; et al. Journal of Alternative and Complementary Medicine, 2000 February, 6(l):19-29.
Vitamin-mineral supplementation significantly increased the nonverbal intelligence of a minority of American schoolchildren. Parents of children with low academic performance should obtain a full nutritional assessment." - Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)
| "Some studies have demonstrated that eleva-
12 O tions in the level of an amino acid called homocysteine are associated with increased risk for stroke and a loss of cognitive performance characteristic of Alzheimer's disease. Folic acid and vitamins B]2 and B6 are co-factors in homocysteine's metabolic pathways, and their presence in the body may potentially lower levels of this substance. This has prompted some physicians to recommend the three vitamins as supplements." - Peter J. Whitehouse and Daniel George, The Myth of Alzheimer's: What You Aren't Being Told About Today's Most Dreaded Diagnosis (Get the book.)
| "I believe that the bias currently shown in the medical community against coenzyme Qio is very similar to medicine's twenty-five-year-long rejection of the homocysteine theory of Kilmer McCully the brilliant pioneer in homocysteine research. It took a very long time, but mainstream medicine now embraces Dr. McCully's revolutionary findings.
BACKGROUND AND STUDIES OF COENZYME Q10
Anyone can purchase any number of brands of coenzyme Qi0 in health food stores today." - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.)
| "For example, the enzyme cystathionine P-synthase catalyzes homocysteine and serine to form cystathionine. Individuals with a defective form of this enzyme develop very high blood and urine homocysteine levels that can cause a variety of symptoms, including mental retardation, vascular and skeletal problems, and optic lens dislocation. It has been found that roughly one half of cystathionine |3-synthase deficient patients respond well to very high doses of vitamin B-6, the coenzyme for cystathionine (3-synthase, which can lower their homocysteine and serine concentrations to normal levels." - Dr. Abram Hoffer, MD, FRCP (C) and Dr. Harold D. Foster, PhD, Feel Better, Live Longer with Vitamin B-3 (Get the book.)
| "Folic acid is important in fighting cardiovascular disease and reducing levels of homocysteine, an amino acid responsible for inflaming and damaging blood vessels and associated with osteoporosis. Folic acid, vitamin B6, and vitamin B12 all can reduce levels of homocysteine.
Pregnant women have a special need for folic acid because it's key to fetal development and nervous system functioning. The same goes for women who are planning pregnancies." - James Dowd and Diane Stafford, The Vitamin D Cure (Get the book.)
| "PubMed ID 16177198) is entitled "Long-term consumption of a raw food diet is associated with favorable serum LDL choles-
terol and triglycerides but also with elevated plasma homocysteine and low serum HDL cholesterol in humans."
A reduction of some cardiovascular disease risk markers manifested in subjects on raw foods. However, the study emphasizes that raw fooders must make certain to take Vitamin Bi2 supplements, or they may accumulate excess homocysteine, a risk factor in heart disease and a marker for B,2 deficiency. (See Chapter 17." - Susan E. Schenck, The Live Food Factor: The Comprehensive Guide to the Ultimate Diet for Body, Mind, Spirit & Planet (Get the book.)
| "B family—including folic acid, B6 and B12—all help control homocysteine levels in the blood. The importance? homocysteine, an amino acid, damages arterial walls. Include supplements in your diet to ensure that you are getting the recommended allowances of these vitamins. Or eat loads of whole grains, seafood and leafy green vegetables. If you have heart problems, you may want to increase amounts of these vitamins—some good target amounts are: 10 mg of B6, 1 mg of folic acid and .1 mg of B12. Discuss this vitamin dosage and any other heart-related supplements you may take with your doctor." - Bottom Line Books, Uncommon Cures For Everyday Ailments (Get the book.)
| "High levels of the amino acid, homocysteine, in the colon and blood may predispose people to both ulcerative colitis and Crohn's disease. It is said to influence other diseases as well, such as Alzheimer's, dementia, depression, ischemic heart disease and stroke, osteoporosis and cancer. Vitamin B6, B12 and folic acid work to decrease homocysteine levels.
Calcium and Magnesium
Calcium and magnesium are useful for people using steroids because they decrease bone mass. It is also one of the more difficult minerals to absorb. However, calcium citrate tends to be better absorbed than carbonate." - Heather Caruso, Your Drug-Free Guide to Digestive Health (Get the book.)
| "B-vitamins help to support normal metabolism of homocysteine.
64. Vrentzos G, Papadakis JA, Malliaraki N, Zacharis EA, Katsogridakis K, Margioris AN, Vardas PE, Ganotakis ES. Association of serum total homocysteine with the extent of ischemic heart disease in a Mediterranean cohort. Angiology. 2004 Sep-Oct;55(5):517-24.
65. Wang G, Mao JM, Wang X, Zhang FC. Effect of homocysteine on plaque formation and oxidative stress in patients with acute coronary syndromes. Chin Med J (Engl). 2004 Nov;l 17(11): 1650-4.
66." - Byron J. Richards, Fight for Your Health: Exposing the FDA's Betrayal of America (Get the book.)
| "High levels of the amino acid, homocysteine, in the colon and blood may predispose people to both ulcerative colitis and Crohn's disease. It is said to influence other diseases as well, such as Alzheimer's, dementia, depression, ischemic heart disease and stroke, osteoporosis and cancer. Vitamin B6, B12 and folic acid work to decrease homocysteine levels.
Calcium and Magnesium
Calcium and magnesium are useful for people using steroids because steroids decrease bone mass." - Heather Caruso, Your Drug-Free Guide to Digestive Health (Get the book.)
| "What are folic acid and homocysteine? Folic acid is a compound derived exclusively from plant-based foods such as green and leafy vegetables. homocysteine is an amino acid that is derived primarily from animal protein.77 This study found that it was desirable to maintain low blood homocysteine and high blood folic acid. In other words, the combination of a diet high in animal-based foods and low in plant-based foods raises the risk of Alzheimer's disease." - T. Colin Campbell, Ph.D. and Thomas M. Campbell II, The China Study: The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications for Diet, Weight Loss and Long-term Health (Get the book.)
| "Serum Folate, Vitamin B12, and homocysteine in Major Depressive Disorder, Part 2: Predictors of Relapse During the Continuation Phase ofPharmacotherapy." Journal of Clinical Psychiatry 65, No. 8 (August 2004): 1096-1098.
Rohr, U. D. "The Impact of Testosterone Imbalance on Depression and Women's Health." Maturitas 41 Supplement (April 2002): S25-S46.
Shaldubina, A., et al. "The Mechanism of Lithium Action: State of the Art, Ten Years Later." Progress in Neuropsychopharmacology and Biological Psychiatry 25 (2001): 855-866.
Tiemeier, H., et al. " - Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)
"Homocysteine, Folate, Methylation, and Monoamine Metabolism in Depression." Journal of Neurology, Neurosurgery and Psychiatry 69, No. 2 (August 2000): 228-232.
Bryce-Smith, D. "Environmental Chemical Influences on Behaviour and Mentation." Chemical Society Review 15 (1986): 93-123.
Chengappa, K. N, et al. "Inositol as an Add-on Treatment for Bipolar Depression." Bipolar Disorder 2 (2000): 47-55.
Cook, E. H., Jr., et al. "Association of Attention Deficit disorder and the Dopamine Transporter Gene." American Journal of Human Genetics 56 (1995).
Delle Chiaie R, et al. "
- Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)
| "This polymorphism is associated with decreased activity of MTHFR and is thought to lead to greater accumulation of serum homocysteine levels.
Vitamin D has anti-inflammatory and antiangiogenic properties, as previously discussed, which may also help prevent DR development and progression. Aksoy et al. observed lower serum l,25(OH)2D3 levels in persons with more severe DR compared to persons without DR among 66 patients with diabetes [333]. However, serum 1,25-dihy-droxyvitamin D is not the preferred marker of vitamin D status due to its short half-life of only hours [334]." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
"Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framing-ham Offspring Study. Am. J. Clin. Nutr. 83, 905-911.
54. Shaw, G. M., Carmichael, S. L., Laurent, C, and Rasmussen, S. A. (2006). Maternal nutrient intakes and risk of orofacial clefts. Epidemiology 17, 285-291.
55. Shaw, G. M., Carmichael, S. L., Yang, W., Selvin, S., and Schaffer, D. M. (2004). Periconceptional dietary intake of choline and betaine and neural tube defects in offspring. Am. J. Epidemiol. 160, 102-109.
56. Miller, L. G. (1990)."
- Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
| "Vitamin B12, Folate, and homocysteine in Depression: The Rotterdam Study." American Journal of Psychiatry 159, No. 12 (December 2002): 2099-2101.
Tuthill, R. W. "Head Lead Levels Related to Children's Classroom Attention-Deficit Behavior." Archives of Environmental Health 51 (1996): 214-220.
Van der Does, A. J. "The Effects of Tryptophan Depletion on Mood and Psychiatric Symptoms." Journal of Affective Disorders 64 (2001): 107-119.
Useful Books
Richard Ash, DHEA: Unlocking the Secrets to the Fountain of Youth (contributor), Detroit Lakes: BL Publications, 1997.
Sidney M." - Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)
| "A polymorphism of the human MTHFR gene that leads to reduced MTHFR activity resulting in elevated plasma homocysteine levels has been described [223]. One large case-control study observed weak differences in risk between levels of dietary intake of folate, vitamin Bi2, vitamin B6, alcohol, and MTHFR 611 polymorphism [156]. However, reduced colon cancer risk was observed with at least one variant allele in the thymidylate synthase gene and low folate consumption [224]." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
| "Recent research has shown that homocysteine levels in the blood are much more strongly associated with heart disease than cholesterol.2 In fact, homocysteine may help raise blood cholesterol. The association of high blood cholesterol with heart disease may be due more from homocysteine (derived primarily from protein found in meat and dairy products) than from cholesterol (or saturated fat).
The important thing to remember from all this is that neither saturated fat nor cholesterol cause heart disease." - Bruce Fife and Jon J. Kabara, The Healing Miracle of Coconut Oil (Get the book.)
"Other risk factors associated with heart disease include high blood pressure, age, gender (being male), tobacco use, diabetes, obesity, stress, lack of exercise, insulin levels, and homocysteine levels. High blood cholesterol is no more the cause of heart disease than age or being a male is. It's guilty only by association.
Blood levels of homocysteine is one of the most accurate of the risk factors. homocysteine is an amino acid derived from protein found in meat, milk, and other foods."
- Bruce Fife and Jon J. Kabara, The Healing Miracle of Coconut Oil (Get the book.)
| "Since 1998, when the United States and Canada started fortifying grain products with folic acid, one measurable result in large population studies has been increased blood levels of folic acid (folate) and decreased homocysteine levels. Researchers also noted a decline in stroke-related deaths in the United States between 1998 and 2002. In England and Wales, where grain fortification didn't take place, a similar decline in stroke death was not observed." - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)
"Getting enough of three of the Bs-B6, B12, and especially folic acid-probably helps because one of their health benefits is breaking down homocysteine.
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(like body temperature), so a doctor will take your blood pressure if you're in the office for just about anything—gynecological checkups, sick visits, and so on. If you can, keep track of the numbers for your reference. General recommendations, however, call for blood pressure screenings at least every 2 years. If your numbers are normal, you can stick with that schedule."
- Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)
"It helps protect against heart disease by helping to control homocysteine levels and thus reduce the risk of heart attack and stroke. Like B6, B12 has an important role in building and maintaining the sheaths that protect nerve fibers. B12 is needed, together with folic acid, for cell formation and growth and to help manufacture red blood cells.
So it should be simple enough to whip up a meal including these three Bs and reap the health benefits, right? Not quite so easy, folks—it gets a bit tricky."
- Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)
"Levels of high-density lipoprotein (HDL, or "good") cholesterol increased only in the
UCLA study, which also reported that AGE did three other beneficial things to lower the risk of heart disease: lowered homocysteine levels, stimulated circulation, and inhibited dangerous plaque formation in arteries. Another benefit to consider: AGE is formulated with S-allylcysteine, not allicin, so the characteristic garlic odor is absent.
Onions may help protect against heart disease and stroke. Onions are one of the richest sources of quercetin on the planet."
- Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)
| "The relationship between MTHFR gene polymorphisms, plasma homocysteine levels and diabetic retinopathy in type 2 diabetes mellitus. Chin. Med. J. (Engl.) 116, 145-147.
333. Aksoy, H, Akcay, F., Kurtul, N., Baykal, O., and Avci, B. (2000). Serum 1,25 dihydroxy vitamin D (l,25(OH)2D3), 25 hydroxy vitamin D (25(OH)D) and parathormone levels in diabetic retinopathy. Clin. Biochem. 33, 47-51.
334. Jones, G, Strugnell, S. A., and DeLuca, H. F. (1998). Current understanding of the molecular actions of vitamin D. Physiol. Rev. 78, 1193-1231.
335. Taverna, M. J., Sola, A., Guyot-Argenton, C, et al." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
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