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"For several years, grape seed extract was all the rage. As it turns out, grape skin extract, also called Resveratrol, is equally powerful. In controlled studies, Resveratrol has been shown to reduce skin cancer tumors by up to 98%, to stop production of leukemia cells. In addition, it works as a Cox inhibitor, thus halting the spread of cancer throughout the body. • grape seed extract?0 mg (84-93%) Similar to green tea, the active ingredients in grape seed extract are the proan-thocyanidins (but in a different combination and ratio)." - Jon Barron, Lessons from The Miracle Doctors: A Step-by-Step Guide to Optimum Health and Relief from Catastrophic Illness (Get the book.)

"A cell study using advanced human prostate cancer cells found that treatment with grape seed extract inhibited cell growth and caused them to die. Another study showed that drinking four or more glasses of red wine per week cut the risk of prostate cancer in half. COGNITIVE FUNCTION: Concord grape juice significantly improved laboratory animals' short-term memory in a water maze test, as well as coordination, balance, and strength. WEIGHT CONTROL: A study found that grape seed extract may be helpful in limiting absorption and accumulation of dietary fat in cells observed under a microscope." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"The importance of the proanthocyanidins in grape seed extract is that they are water soluble and highly bio-available. Above all else, grape seed extract is known as a defender of the circulatory system. It improves peripheral circulation, revives declining capillary activity by up to 140%, and increases vascular response by some 82%. It repairs varicose veins and aids in the prevention of bruising." - Jon Barron, Lessons from The Miracle Doctors: A Step-by-Step Guide to Optimum Health and Relief from Catastrophic Illness (Get the book.)

"Flavonoids, grape seed extract, and Pycnogenol. Plant compounds called flavonoids, proanthocyanidins, and antho-cyanidins are all helpful in the treatment of varicose veins. All seem to help strengthen the delicate walls of the veins and capillaries. Foods richest in these substances include berries (blueberries and blackberries) as well as cherries, grapes, and tea. Add these foods to your diet and take a supplement of grape seed extract, which is rich in these compounds. 4. Vitamin C." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Researchers at the University of California at Davis gave a small group of such patients and some nonhypertensives either grape seed extract or placebo. Those taking the grape seed (150 or 300 milligrams daily) experienced an average drop of 12 points in their systolic BP and 8 points in their diastolic BP.622 The investigators speculate that grape seed extract may work by dilating blood vessels. Managing Your Medicines Successful treatment of hypertension requires medical supervision. It is not a do-it-yourself project." - Joe Graedon, M.S. and Teresa Graedon, Ph.D., Best Choices From the People's Pharmacy (Get the book.)

"WEIGHT CONTROL: A study found that grape seed extract may be helpful in limiting absorption and accumulation of dietary fat in cells observed under a microscope. Tips on Using Grapes SELECTION AND STORAGE: • Look for grapes that are intact, plump, and free of wrinkles. • Red grapes should be mostly red, green grapes should have a slight yellowish hue, and blue-black and purple grapes should be deep in color. • Wrap unwashed grapes in a paper towel, place in a plastic bag, and put in the refrigerator for longer storage. • Grapes will keep fresh for several days at room temperature." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.) "November). grape seed extract induces apop-totic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release. Carcinogenesis. 23(11), 1869-1876. Albers AR et al. The antiinflammatory effects of purple grape juice consumption in subjects with stable coronary artery disease. Arterioscler Thromb Vase Biol. 2004 Nov;24(ll):el79-180. Falchi M et al. Comparison of cardioprotective abilities between the flesh and skin of grapes. J Agric Food Chem. 2006 Sep 6;54(18):6613-6622." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.) "Inhibitory effects of grape seed extract on lipases. Nutrition. 11(10), 876—879. Shukitt-Hale B et al. Effects of Concord grape juice on cognitive and motor deficits in aging. Nutrition. 2006 Mar;22(3):295-302. Guava www.hort.purdue.edu/newcrop/morton/guava.html Abdelrahim, S. I., et al. Antimicrobial activity of Psidium guajava L. Fitoterapia. 2002; 73(7-8): 713-715. Arima H et al. Isolation of antimicrobial compounds from guava (Psidium guajava L.) and their structural elucidation. Biosci Biotechnol Biochem. 2002; 66(8): 1727-1730. Cheng JT et al." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"Grape Seed Extract A compound very similar in composition to Pycnogenol is grape seed extract. It also contains a high proportion of anthocyanins. Although Pycnogenol was the first anthocyanin supplement to appear in the United States, grape seed extract (depending on the brand) is usually more potent, containing between 92 to 95 percent bioflavonoids, compared to 85 percent for Pycnogenol. Cost Grape seed extract is considerably less expensive than Pycnogenol. It is available for about 20c per tablet." - Ralph Moss, PhD, Antioxidants Against Cancer: How to activate your bod natural healing powers with today's most protective and immune-boosting supplements and foods (Get the book.)

"Blue Green Algae with grape seed extract Moisturizer SPF 15, for Combination/ Oily Skin ($16.28 for 4 ounces) is nearly identical to the Green Tea & Ginkgo Moisturizer SPF 15, for Normal Skin, above and the same review applies. © Blue Green Algae with grape seed extract Soothing Mask, for Combination/Oily Skin ($8.98 for 4 ounces) is similar to the Green Tea & Green Clay Rejuvenating Mask, for Normal Skin, above except this adds lavender oil, which makes it too irritating. AUBREY ORGANICS OILY SKIN 5 © Natural Herbal Facial Cleanser, for Oily Skin ($12." - Paula Begoun and Bryan Barron, Don't Go to the Cosmetics Counter Without Me, 7th Edition (Get the book.)

"Matrix assisted laser desorption/ionization time of flight mass spectrometry of polygalloyl polyflavan-3-ols in grape seed extract, J Agric Food Chem 48: 1663-1667. Krueger, C. G., Vestling, M. M. and Reed, J. D., 2003, Matrix-assisted laser desorption/ionization timeof-flight mass spectrometry of heteropolyflavan-3-ols and glucosylated heteropolyflavans in sorghum [Sorghum bicolor (L.) Moench], J Agric Food Chem 51: 538-543. Le Gall, G., DuPont, M. S., Mellon, F. A., Davis, A. L., Collins, G. J., Verhoyen, M. E. and Colquhoun, I. J." - Erich Grotewold, The Science of Flavonoids (Get the book.)

"Human studies have confirmed these findings in smokers,318 and a combination of 100 mg grape seed extract and 200 meg chromium two times daily was found to significantly decrease total and LDL cholesterol up to 20 percent.319 PCO 50-300 mg per day Gugulipid (Commiphora Mukul). The mukul myrrh tree, native to India, Pakistan, and Afghanistan, is the source of standardized gugulipid extract. The extract is further concentrated to isolate compounds known as guggulsterones. The two guggulsterones important in the management of hyperlipidemia are Z-guggulsterone and E-guggulsterone." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"Add these foods to your diet and take a supplement of grape seed extract, which is rich in these compounds. 4. Vitamin C. Vitamin C in combination with a bioflavonoid called hesperidin has been used in research (often with butcher's broom) with good effect. It helps promote better circulation and strengthens the walls of the veins. Lack of these nutrients has also been shown in research to increase pain in the limbs and fragility in the capillaries. Huperzine A for Dementia and Alzheimer's LET'S BE CLEAR about one thing: There's no known ^gjJjjP\ cure for Alzheimer's disease at this time." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.) "Other ingredients you may see on the ingredients list in a glucosamine-chondroitin formula may include sea cucumber (Cucumaria frondosa), grape seed extract, boswellia, and turmeric, all of which have varying degrees of anti-inflammatory action. Exercise for Arthritis You may feel like exercise is out of the question if you have arthritis. Not so. Moderate exercise can be your best friend—building strong muscles around the joints can go a long way toward relieving joint pain, not to mention the benefits exercise provides to overall endurance, well-being, and mood." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"In addition, grape seed extract is synergistic with vitamin C, vastly increasing vitamin C activity and strengthening collagen activity—including in the connective tissue of the arterial wall and the skin. • Chaparral extract?75 meg The active antioxidant in Chaparral, a lignan called Nordihydroguaiaretic Acid (NDGA), has been shown to specifically target vittually all forms of herpes virus—and has been shown to be up to 97.5% effective. It also is an effective counter to radiation induced free radical damage." - Jon Barron, Lessons from The Miracle Doctors: A Step-by-Step Guide to Optimum Health and Relief from Catastrophic Illness (Get the book.)

"Antioxidant cosmeceutical ingredients include vitamins such as B-5 (and its synthetic derivative panthenol), C, E, and nicotinamide; lycopene; polyphenols such as coffeeberry in coffee plant fruit and resveratrol in grapes; genistein, the isoflavone in soy milk and fermented soy; EGCG (epigallocatechin-3-gallate); pycnogenol, an extract of French marine pine bark; grape seed extract; and DMAE, found in cold-water fish, particularly salmon. 6. Tyrosinase Inhibitors." - Samuel S. Epstein, Randall Fitzgerald, Toxic Beauty: How Cosmetics and Personal Care Products Endanger Your Health . . . And What You Can Do about It (Get the book.)

"Among these are: pycnogenol, which is a water extract from the bark of the French maritime pine; grape seed extract; tocotrienols; vitamin C ester; alpha lipoic acid; dmae; and alpha and beta hydroxy acids. On the other hand, a poor diet, processed foods, cured meats, tobacco smoke, infections, alcohol, stress, air pollution, pesticides, and radiation all promote oxidation in the human body. Even if we are minimizing the effects of the aforementioned free radical developers, given our modern urban, industrialized, and technological lifestyles, we cannot completely avoid them." - Ron Garner, Conscious Health: A Complete Guide to Wellness Through Natural Means (Get the book.)

"Supplementation with cranberry extract, grape skin extract, and grape seed extract seems to me prudent and inexpensive insurance. Want more antioxidant protection? Pycnogenols-combinations of polyphenols from tree bark and alpha lipoic acid-are superb antioxidants, as are mushroom extracts, especially reishi, cordyceps, or maitake. All enhance immune-system function, elevate the level of natural killer cells (another type of white blood cell that protect us), and improve athletic performance." - Dr. Steven R. Gundry, Dr. Gundry's Diet Evolution: Turn Off the Genes That Are Killing You - And Your Waistline - And Drop the Weight for Good (Get the book.)

"Naturally occurring in grape seed extract and pine bark extract. 10 mg two times daily with meals VITAMINS AND NUTRIENTS vitamin C vitamin E DAILY DOSE 1-3 grams ?400 IU ?200 mg (gamma-tocopherol) ?65 mg (palm oil-derived tocotrienols) COMMENTS Mixed tocopherols with an emphasis on gamma. Additional Supplements for Impacting Depression The following chart summarizes additional supplements I recommend for individuals who suffer from, or are specifically concerned about, depression." - Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)

"Chelators like IP6 from rice bran, and to a lesser extent green tea, milk thistle, grape seed extract, and other bioflavonoids, help to control loose iron. cal Assoc. 96:641-9, 2004] The only meaningful iron score would be to know how much iron is being released (free iron) in the prostate gland. Saudi Arabia is a sunny, desert country located at about 24 degrees North Latitude, so its citizens are likely exposed to more sun. However, Arabic men in Saudi Arabia are often vitamin D deficient due to lack of sun exposure." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.)

"In animal studies, grape seed extract has been shown to protect the interior of blood vessels against powerful caustic agents.390 The extract protects blood vessels by several mechanisms, but primarily by protecting them from destructive enzymes, such as collogenase and elastase. Several human studies have shown a significant improvement in cases of poor blood supply to the legs, with improvement in symptoms varying from 74 percent for tingling and numbness to 67 percent for night cramps." - Russell L. Blaylock, M.D., Health and Nutrition Secrets (Get the book.)

"Both grape skin extract and grape seed extract have a few heart-healthy properties — but together, they're a dynamic duo. That's why grape juice, made from whole grapes, is an artery-clearing wonder. It protects your artery walls from cholesterol because of several powerful substances. Quercetin, a flavonoid found in the skin, acts as an antioxidant to prevent LDL cholesterol from collecting on your artery walls. Resveratrol, also found in the skin, thwarts inflammation and blood clots." - The Editors of FC&A, Unleash the Inner Healing Power of Foods (Get the book.) "PCO is also found inside grape seeds and is sold as pine bark (pycnogenol) or grape seed extract. You can get these antiox idants naturally, however, from grape skins, other citrus peels, apples, onions, blueberries, cranberries, and peanuts. studies, they found that zinc actually helps other substances shield your eyes from AMD. People who took zinc along with vitamins C, E, and beta carotene were less likely to get AMD than those taking just the vitamins or zinc." - The Editors of FC&A, Unleash the Inner Healing Power of Foods (Get the book.)

"Epicatechin is found in grape seed extract as well as green and white tea, which may explain in part why their consumption improves cognitive ability.46' Hormones also play a vital role in preserving our brains. As we age, DHEA—an adrenal hormone precursor for production of the reproductive hormones estrogen and testosterone— levels begin to fall. Interestingly, the brain contains receptors for DHEA, and several studies have shown that these receptors are capable of protecting the brain against damage.470 Depression is a major problem in the elderly and DHEA may be able to help." - Russell L. Blaylock, M.D., Health and Nutrition Secrets (Get the book.) "When buying grape seed extract, be sure to get a brand that says "guaranteed potency with 85 percent proanthocyanidins." Most studies used doses from 150 to 300 mg a day. To maintain good blood vessel strength, I recommend 100 mg a day minimum. In general I divide supplements into those needed for maintenance and those used to treat an existing disease. While the vegetarian diet supplies most of the nutrients, some people will need to be boosted for added protection. Follow the program below that best fits your health needs." - Russell L. Blaylock, M.D., Health and Nutrition Secrets (Get the book.)

"Ginger -h Green tea polyphenols Pycnogenol or grape seed extract ??Milk thistle ?* Rosemary ??Turmeric Step 4: Use Supplements to Reduce Your Oxidation Adding these supplements to your standard regimen can be a powerful aid in helping you reduce the effects of "rusting" so you can lose weight and be healthy. A note on supplements: There are many special supplements that have multiple benefits across multiple keys." - Mark Hyman, Ultra-Metabolism: The Simple Plan for Automatic Weight Loss (Get the book.) "Pycnogenol or grape seed extract ??Rutin • ?Probiotics such as Lactobacillus and Bifidobacter species help normalize gut flora and reduce endotoxins (toxins produced by imbalances in the gut bacteria). Step 6: Consider Testing Your Detoxification System and Looking for Toxins Sometimes doing a little detective work to find out where your genetic detoxification weak spots are and learning how to support them with diet and supplements can be very helpful. Finding hidden toxins is also important. Mercury is probably the most important toxin to look for if you are chronically ill." - Mark Hyman, Ultra-Metabolism: The Simple Plan for Automatic Weight Loss (Get the book.)

"Melatonin is joined by pycnogenol (pine bark or grape seed extract), bilberry extract, and turmeric (cucurmin) and Vitamin C in their ability to elevate GTH levels. Cholesterol, when oxidized in the blood, sticks to the lipoprotein(a) at the site of vessel injury and begins the cholesterol plaque problem in the wall of an artery. French researchers have shown that low levels of GTH in the blood are directly related to increased amounts of oxidized fats in the blood. Nearly every cataract is correlated with low levels of GTH in the lens." - James A. Howenstine, A Physician's Guide to Natural Health Products That Work (Get the book.)

"Some people may prefer grape seed extract to pycnogenol: both contain similar flavonoids. Quercetin is another flavonoid that has shown great promise in preventing cardiovascular disease. It is the most abundant flavonoid in foods, with the highest levels occurring in onions, tea, cranberries, kale, and apples. Several large epidemiological studies have shown a strong correlation between flavonoid intake and a reduction in heart attacks and strokes." - Russell L. Blaylock, M.D., Health and Nutrition Secrets (Get the book.)

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