Quotes about Glycogen from the world's top natural health / natural living authors
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 "Glycogen in the liver is used to keep blood glucose levels in balance, and the transient shift in phosphoglucomutase activity from glycogen release to glycogen synthesis causes this mild, transient, and clinically insignificant shift in blood sugar levels.
High doses may also cause mild gastrointestinal discomfort or diarrhea, but this is common when any concentrated simple carbohydrate is consumed in high dose. These side effects are very seldom seen at recommended doses, however.
There are no known drug or nutritional interactions associated with ribose use."- Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.) |
 "Since oxygen is necessary for the efficient burning of glycogen, without it your muscles begin to burn creatine and glycogen stored directly in the muscle tissue, a messy mechanism that creates a buildup of lactic acid (the burn you feel in your thighs and chest). The so-called anaerobic threshold occurs at different intensities for different people, but during a high-intensity workout, you want to be flirting with that thigh burn (after warming up) but staying just below it throughout your run."- John J. Ratey, MD, Spark: The Revolutionary New Science of Exercise and the Brain (Get the book.) |
 "Also, excessive exercise during periods of poor glycogen storage can lead to profound hypoglycemia. glycogen, the stored form of glucose, is the first storage site to be tapped during extreme exercise. When someone experiences hypoglycemia, the brain has essentially no glycogen on which to operate.
In children, hypoglycemia can occur with the use of aspirin or other drugs. Certain amino acids, such as leucine, isoleucine, and proline also can stimulate profound hypoglycemia."- Russell L. Blaylock, M.D., Health and Nutrition Secrets (Get the book.) |
 "It's just a trick. As glycogen is burned for energy and water is flushed from your tissues, the machine assumes that there is a greater percentage of fat.
Remember, your brain is constantly looking for glucose. After tapping the glycogen stored in your muscles and liver, where does the brain look next? Unfortunately, it sends signals to your muscles, which are composed of protein, to break down and, via gluconeogenesis, make sugar. In fact, studies of Atkins dieters show that up to 50 percent of the weight loss in the first six months of these diets is muscle.3 Yikes!"- Dr. Steven R. Gundry, Dr. Gundry's Diet Evolution: Turn Off the Genes That Are Killing You - And Your Waistline - And Drop the Weight for Good (Get the book.) |
| "Also, excessive exercise during periods of poor glycogen storage can lead to profound hypoglycemia. glycogen, the stored form of glucose, is the first storage site to be tapped during extreme exercise. When someone experiences hypoglycemia, the brain has essentially no glycogen on which to operate.
In children, hypoglycemia can occur with the use of aspirin or other drugs. Certain amino acids, such as leucine, isoleucine, and proline also can stimulate profound hypoglycemia." - Russell L. Blaylock, M.D., Health and Nutrition Secrets (Get the book.) |
 "In a follow-up study to test the glycogen sparing theory, participants cycled at 60% of their maximum for three hours while drinking one of three beverages as was done in the earlier study. Following the exercise, muscle glycogen levels were measured and found to be the same for all three groups. The conclusion was that MCFA did not spare glycogen stores, yet did improve performance. The improvement in performance was not due to glycogen sparing and must be attributed to some other mechanism."- Bruce Fife and Jon J. Kabara, The Healing Miracle of Coconut Oil (Get the book.) |
| "Aerobic athletes, such as runners, rely heavily on glycogen stores to give them energy during long exercise bouts. Hearts also rely on glycogen as an energy store to protect them from short periods of ischemia when the oxygen-requiring pathways of energy metabolism slow down or stop.
3. Sugars are also used as constituents of cell walls and membranes and in cellular secretions, such as mucous. These sugars attach to proteins forming large, complex compounds called glycoproteins.
4. Ribose is unique among sugars." - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.) |
 "PKB phosphorylates and inactivates various substrates involved in diverse processes including cell survival (the proapoptotic protein BAD), glycogen synthesis (glycogen synthase kinase-3), and gene transcription (FOXO transcription factors) (Cantley, 2002; Fresno Vara et al, 2004; White, 2003). However, PKB is also known to promote cell and organismal growth downstream of PI3K.
Recently, significant additional signaling molecules have been implicated in the mechanism(s) responsible for the antitumor effects of the flavonoids and tea polyphenols."- Erich Grotewold, The Science of Flavonoids (Get the book.) |
 "Any carbohydrates not immediately used by the body will be stored in the form of glycogen (a long string of glucose molecules linked together). The body has two storage sites for glycogen: the liver and the muscles. The glycogen stored in the muscles is inaccessible to the brain. Only the glycogen stored in the liver can
be broken down and sent back to the bloodstream to maintain adequate blood sugar levels for proper brain function.
The liver's capacity to store carbohydrates in the form of glycogen is very limited and can be easily depleted within ten to twelve hours."- Ellen W. Cutler, Winning the War Against Asthma and Allergies (Get the book.) |
| "Since oxygen is necessary for the efficient burning of glycogen, without it your muscles begin to burn creatine and glycogen stored directly in the muscle tissue, a messy mechanism that creates a buildup of lactic acid (the burn you feel in your thighs and chest). The so-called anaerobic threshold occurs at different intensities for different people, but during a high-intensity workout, you want to be flirting with that thigh burn (after warming up) but staying just below it throughout your run." - John J. Ratey, MD, Spark: The Revolutionary New Science of Exercise and the Brain (Get the book.) |
 "This rise in insulin increases peripheral glucose utilization and glycogen storage and lowers glucose levels but this shifts as the pregnancy progresses. There are increased levels of human chorionic gonadatropin (HCG) which also leads to insulin resistance. Cortisol, which has the highest diabetic creating potency, peaks at twenty-six weeks. Progesterone, with anti-insulin qualities, peaks at thirty-two weeks. These two milestones, twenty-six and thirty-two weeks, encompass an important time during which the pancreas releases 1.5 to 2.5 times more insulin to respond to the resistance."- Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.) |
| "Hearts also rely on glycogen as an energy store to protect them from short periods of ischemia when the oxygen-requiring pathways of energy metabolism slow down or stop.
3. Sugars are also used as constituents of cell walls and membranes and in cellular secretions, such as mucous. These sugars attach to proteins forming large, complex compounds called glycoproteins.
4. Ribose is unique among sugars. It is the only sugar used by the body to regulate and control a vital metabolic pathway." - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.) |
| "The researchers also found that the glycogen depletion in the liver and lipid accumulation in diabetic animals was reversed. In another study of Type-2 diabetics, twenty-two were given this herbal extract along with their own oral hypoglycemic drugs. All of these people had an improved blood sugar control. Twenty-one of the subjects were able to reduce their drug dosage significantly. Five were able to discontinue their medication and maintained blood sugar control with this herb alone.174
Dosage: The average dose per day in many of these studies was 400 mg." - Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.) "Part of the issue is that the ability to move from glycogen to glucose is blocked within the cells and there is a backup. This whole system is somewhat affected by free radical production associated with hyperinsulinemia. This elevated free radical production activates Nuclear Factor kB, which is a DNA regulator that acts within the cell nucleus. NFkB activation intensifies inflammatory responses, resulting in more production of free radicals and eventually beta-cell death. So we begin to see that diabetes is also associated with inflammation." - Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.) "Whether it is because it can't move from glycogen to glucose and therefore creates a glucose backup, or because glucose cannot get into the cell, the detrimental fatty foods seem to either disable the genes so they are not able to produce more mitochondria or eliminate the fat. Most likely, both mechanisms occur. Theoretically, the point is that a high-saturated-cooked-animal-fat, high-trans-fatty-acid, high-refined-carbohydrate diet decreases the healthy anti-diabetes gene expression and precipitates the onset of Type-2 diabetes." - Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.) |
| "Only three molecules of ATP are formed for each molecule of glucose metabolized from glycogen, the cellular storehouse of glucose. Only two molecules of energy are formed when metabolism begins with glucose alone. Lots of fuel is consumed with a small energy return via this inefficient pathway.
In normal metabolism, glucose, a six-carbon carbohydrate, is converted down the glycolytic pathway to form two molecules of pyruvate, a three-carbon compound used by the cell to feed the Krebs cycle found in the mitochondria." - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.) |
 "Glycation leads to the development of advanced glycation end products. glycogen: A substance that serves as the main source of stored energy in the body. It is composed of sugars, is srored in the liver and muscles, and is released into the bloodstream as needed, hemoglobin A (Hb Au): The component of red blood cells that transports oxygen to the cells and sometimes binds (glycates) with glucose. The more excess glucose you have in your blood, the more hemoglobin gets glycated. A Hb Ak test measures the percentage of A in the blood."- Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.) "That's where chlorogenic acid comes in: it can inhibit the gene expression of an important enzyme involved in generating glucose from glycogen, and thus can reduce glucose production. In a trial at the Moscow Modern Medical Center, seventy-five healthy volunteers were given either 90 mg of chlorogenic acid daily or a placebo. Blood glucose levels of the chlorogenic acid group were 15 to 20 percent lower than those of the placebo group. Scientists have also shown that chlorogenic acid can decrease the absorption rate of glucose." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.) "Insulin also plays a major role in how the body uses amino acids to build proteins, and it helps stimulate growth and tissue development by preventing the abnormal breakdown of proteins, fats, and the storage form of glucose, called glycogen. Beta cells can sense the amount of glucose in the blood. When they sense that blood glucose levels are rising, which occurs after eating, they secrete more insulin into the bloodstream so it can signal, for example, muscle cells to "take up" glucose (allow glucose to enter the cell through the cell membrane)." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.) |
 "Vitamin B6 is needed by a coenzyme that helps release blood sugar from glycogen (stored blood sugar). Only 13 percent of the Vitamin B6 in whole wheat remains after it is refined into white flour. White rice contains only 34 percent of the vitamin B6 present in brown rice. Vitamin B6 is not normally added back to grains during enrichment. Unfortunately, the vitamin B6 content of other common carbohydrates, such as sugar, high fructose corn syrup, and alcohol is very low. Without enough vitamin B6, it is more difficult to burn carbohydrates."- Dr. Steve Blake, Vitamins and Minerals Demystified (Get the book.) |
 "The liver also stores glycogen and filters out drugs and poisonous substances that would otherwise accumulate in the bloodstream.
The liver is extremely resilient. Up to 75 percent of its cells can be destroyed or surgically removed before it ceases to function. The most common cause of liver disease in the United States is alcohol consumption. Hepatitis is also a common liver disease.
Considering the important role the liver plays in our bodies, it is critical to keep it healthy and functioning."- Tom Bohager, Everything You Need to Know About Enzymes to Treat Everything from Digestive Problems and Allergies to Migraines and Arthritis (Get the book.) |
 "Be sure to follow a diet that emphasizes complex carbohydrates to replace muscle glycogen lost during exercise, thereby minimizing the risk of fetal ketosis (elevated ketones in the body tissues).
9. Participation in competitive team sports is acceptable in the first 15 weeks of pregnancy, although there are potential but unproved risks for fetal loss from pelvic trauma, abdominal trauma, or both.
10. Avoid exercises such as weight lifting, especially in the third trimester.
Tips for Safe Weight Training During Pregnancy
1. Do not compete, not even with yourself.
2."- Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.) |
 "When muscle cells are deprived of oxygen, they deplete glycogen, a chemical used to store energy. Depletion of glycogen in the muscles and the accumulation of lactic acid are associated with fatigue and muscle soreness. Ginseng is said to have a "glycogen-sparing effect," shifting energy production away from glycogen and toward fatty acids, which reduces fatigue and enhances physical performance.21
Other Effects
Research shows that the isolated ginseno-sides Rg3 and Rh2, polyacetylenes, and polysaccharides possess antitumor activity."- Robert S. McCaleb, Evelyn Leigh, and Krista Morien, The Encyclopedia of Popular Herbs (Get the book.) |
| "Water (along with the electrolytes: sodium, potassium, magnesium, calcium, and phosphorus) is initially lost rapidly when the body breaks down glycogen and protein. The glycogen and proteins inside the liver and muscle cells are tree-shaped, branched molecules surrounded by water. There is three times as much water within the cells as there is protein and glycogen. So every time the liver breaks down an ounce of glycogen or protein, three ounces of water are released from the cell, transported to the kidneys, and excreted as urine." - C. Wayne Callaway, Catherine Whitney, Kristine Mehring, Surviving With AIDS: A Comprehensive Program of Nutritional Co-Therapy (Get the book.) |
| "To best improve insulin sensitivity and glucose uptake by muscle cells, you should focus on exercise that stresses the glycogen system.
Effect on Metabolic Syndrome
Physical activity has an impact on the other factors that are part of insulin resistance—blood pressure, triglyceride levels, and HDL cholesterol levels. Many studies have shown that regular physical activity improves blood pressure, reduces LDL cholesterol levels, raises HDL cholesterol levels, and lowers triglyceride levels. All of these improvements are helpful in reducing the risk of heart disease." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.) |
 "This weight loss is temporary and if carbohydrate intake is increased, the glycogen stores are repleted and body weight increases accordingly. On very low carbohydrate diets, the body goes through a period of ketogenesis to provide fuel that can be utilized by the brain cells. Ketones are potent appetite depressants, and lack of appetite may be one reason why individuals, at least temporarily, follow such restrictive diets.
It has only been recently that carefully controlled trials have evaluated the efficacy of these types of diets for weight loss."- Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.) |
 "In the liver and skeletal muscle cells, for example, insulin encourages the production of glycogen (the storage form of glucose). Insulin also encourages fat production, which is the body's long-term storage solution for excess glucose.
There are three basic forms of diabetes: type 1, type 2, and gestational. Type 1 is a form of diabetes that children get and is usually not associated with obesity. About 5 to 10 percent of Americans with diabetes have this form, which results when the pancreas literally stops making insulin."- Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.) |
| "Following the exercise, muscle glycogen levels were measured and found to be the same for all three groups. The conclusion was that MCFA did not spare glycogen stores, yet did improve performance. The improvement in performance was not due to glycogen sparing and must be attributed to some other mechanism.
** The medium-chain fatty acids (MCFA) most often used in sports drinks and energy bars are in the form of medium-chain triglyceride oil (MCT oil). They are usually indicated as "MCT" on food, supplement, and infant formula labels." - Bruce Fife and Jon J. Kabara, The Healing Miracle of Coconut Oil (Get the book.) |
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