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NaturalPedia > Gene Therapy
Quotes about Gene Therapy from the world's top natural health / natural living authors
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"Further, longer-term follow-up studies to assess the permanence of the symptom reductions were not conducted.
IX. gene therapy FOR LACTOSE INTOLERANCE
Although conventional dietary therapies for lactose intolerance exist, the possibility of gene therapy for lactase nonpersistence was examined by During et al. [136]. An adeno-associated virus vector was orally administered to hypolactasic rats to increase lactase mRNA. The adeno-associated virus vector is a defective, helper-dependent virus and the wild type is nonpathogenic in humans and other species." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
| "The object of gene therapy is to allow normal genes to be inserted into a patient's cells to replace or counteract defective or missing genes. There are two types of gene therapy. Somatic gene therapy corrects a problem in a particular patient, but these corrections are not inherited by the next generation. This is the type of therapy that is being researched today. The second type is called germline (egg or sperm) gene therapy, and this involves modification of cells that will be passed on to the next generation." - Garcia Oz, Sharyn Kolberg, The Healthy High-tech Body (Get the book.)
| "Dietary Management for Lactose Maldigestion 761
IX. gene therapy for Lactose Intolerance 765
X. Summary 765 References 766
I. INTRODUCTION
Ingestion of a large single dose of lactose (e.g., 50 g, the quantity in a quart of milk) by lactose maldigesters commonly results in diarrhea, bloating, and flatulence [1], The wide dissemination of this information has led some of the lay population and a fraction of the medical community to attribute common gastrointestinal symptoms to lactose intolerance, independent of the dose of lactose ingested." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
"Thus, the potential of gene therapy for lactose intolerance is an interesting prospect, but this has not been studied in humans.
X. SUMMARY
A majority of the world's population and approximately 25% of the U.S. population are lactose maldigesters. Milk and milk products not only contain lactose, but also are important sources of calcium, riboflavin, and high-quality protein. Some maldigesters may avoid dairy products because of the perception that intolerance symptoms will inevitably follow dairy food consumption."
- Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
"Peroral gene therapy of lactose intolerance using an adeno-associated virus vector. Nat. Med. 4, 1131-1135.
CHAPTER Hi 1
Nutritional Considerations in the Management of Celiac Disease
MICHELLE PIETZAK
University of Southern California Keck School of Medicine, Los Angeles, California
Contents
I. Introduction 771
II. Symptoms of Celiac Disease 771
III. Diagnosis of Celiac Disease 775
IV. Treatment of Celiac Disease with a Gluten-Free
Diet 777
V. Management of the Complications of Celiac Disease 779
VI. Summary 780 References 781
I."
- Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
| "A scientific panel criticized much of the hype surrounding these studies, some of which were of a commercial nature. gene therapy studies have since been abandoned because of deaths associated with the gene experiments. But researchers are reluctant to call gene therapy a failure, instead characterizing it as having "progressed slower than anticipated." [Annals Internal Medicine 132:549-60, 2000]
Genetic testing
A woman whose mother and older sister have developed breast cancer might want to know of her genetic predisposition for breast cancer." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.)
| "Another related therapeutic approach that is attracting considerable attention is the process of implanting genetically modified cells in the brain that produce nerve growth factor, a protein that prevents neuronal death and stimulates cell function. This gene therapy approach—which is being promoted by scientists at the University of California, San Diego, and the company they founded called Ceregene—enables scientists to create a designer stem cell. Rather than starting with stem cells, this treatment starts with skin cells called fibroblasts that are taken from individual patients." - Peter J. Whitehouse and Daniel George, The Myth of Alzheimer's: What You Aren't Being Told About Today's Most Dreaded Diagnosis (Get the book.)
| "Experimental therapies are being explored, including electrical nerve stimulation to activate the inhibitory circuits and decrease the sensation of pain, intravesical injection of botulinium toxin, gene therapy, and nerve growth-factor inhibitors. Surgical interventions are currently considered a last resort. These include surgical removal of visible ulcers, laser denervation, or removing a part of the colon and attaching it to the bladder to increase bladder capacity." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)
| "Michael Antoniou, a molecular geneticist who does human gene therapy, says genetic modification "technically and conceptually bears no resemblance to natural breeding." In normal sexual reproduction, genomes from both parents contribute thousands of genes to the offspring; these get sorted and expressed in a highly regulated and natural way. Plant breeders have worked with this system for thousands of years by selecting parents with desired characteristics, such as yield or disease resistance, in the hopes that the offspring express both." - Jeffrey M. Smith, Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods (Get the book.)
| "Its diagnostic and therapeutic functions utilize a microscopic, lipid-based liposome and an antibody, along with gene therapy; expected to enter clinical studies soon.
Nanotube Bomb enters cancer cells and when exposed to lasers, explodes along with the cancer cell. Scientists suggest this future scenario: "after work, people take their 'Lab-on-a-Chip' to a clinic for a quick screen; if cancer is present they receive an injection of nanobo-mbs, sit under the laser for a few minutes, and then go home". Widespread use expected by 2010.
Will the fraudsters ever be punished?" - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.)
"Butyrate is gene therapy. [Oncological Research 14: 427-38, 2004]
—? Butyrate also works as a natural COX-2 inhibitor, working in a similar fashion to COX-2 inhibiting drugs, but without the cardiovascular side effects. [Biochemical Biophysical Research Communications 317: 463-71, 2004]
þ Butyrate reduces the metastatic properties of colon cancer cells so they won't easily spread to the liver, which is a highly mortal sign. [Clinical Experimental Metastasis 21: 331-38, 2004]
Published reports on the effectiveness of butyrate in inhibiting colon cancer are mixed."
- Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.)
"But researchers are reluctant to call gene therapy a failure, instead characterizing it as having "progressed slower than anticipated." [Annals Internal Medicine 132:549-60, 2000]
Genetic testing
A woman whose mother and older sister have developed breast cancer might want to know of her genetic predisposition for breast cancer. Knowing that the BRCA1 gene, when mutated, does increase the risk for breast cancer among women, testing can help identify at-risk individuals. However, only 5 to 10% of all cases of breast or ovarian cancer are believed to stem from defective BRCA1 and BRCA2 genes."
- Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.)
| "It has not looked at gene therapy or genetically modified medicine. There are fundamental differences. Several scientists working in the field of gene therapy are appalled that genetic technology is being applied to food, which exposes our entire population and ecosystem to unnecessary risks. gene therapy or GM medicine, on the other hand, may limit risks just to those individuals who agree in advance. I invite you to evaluate the other genetic technologies on a case-by-case basis.
This book also does not explore the most dangerous aspect of GM foods—the environmental impact." - Jeffrey M. Smith, Seeds of Deception: Exposing Industry and Government Lies about the Safety of the Genetically Engineered Foods You're Eating (Get the book.)
| "Gene therapy is currently being researched as a possible cure.3,4 Research is also being conducted on methods to decrease levels of phenylalanine in the blood through the use of certain enzymes5 and amino acids.
CHECKLIST FOR PHENYLKETONURIA
j Nutritional Rating Supplements Herbs
þ?ft
Branched-chain amino acids (page 479)
(BCAA)
Fish oil (page 514) (if
PUFA deficient)
L-tyrosine (page 544)
(if deficient)
Selenium (page 584)
(if deficient)
þftft
Vitamin B12 (page 601) (if deficient) Vitamin K (page 612) (if deficient)
What are the symptoms of phenylketonuria?" - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)
| "With the discovery of two "breast cancer genes" (BRCA1 and BRCA2), gene therapy is receiving more attention. This research is still in its infancy and much more investigation in this area needs to be done. Q Biopsies that are less invasive now can be done using a fine needle aspiration (removing cells from a breast lump) and stereotactic core biopsies (which uses a bigger needle that a computer guides to remove suspicious tissue seen on a mammogram)." - Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)
| "Thus, the impact of gene transfer, whether in human gene therapy or transgenic plants, is holistic; gene regulation is an integrated affair. The huge number of changes will alter the types and levels of proteins in significant, but entirely unpredictable, ways. In the cystic fibrosis study, the scientists were at a loss to determine the impact. "In the absence of more biological information," they wrote, "we cannot discern which directions are better or worse, since any of these may have positive or negative effects on the physiology of the CF cell." - Jeffrey M. Smith, Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods (Get the book.)
| "This pioneering landmark has certainly taught us much about the human body and has opened up the exciting and life-saving field of gene therapy. However, the limitations of seeing the genetic process as a linear code of fixed molecules has left many questions unanswered. We are slowly beginning to see beyond the chemistry of the DNA to its mathematical coding, its geometric design and even its poetry.
There are only 26 letters in the Western alphabet, and only eight major notes in an octave." - Robin, Dr. Kelly, The Human Antenna: Reading the Language of the Universe in the Songs of Our Cells (Get the book.)
| "Smith "Geneticist Michael Antoniou, who works on human gene therapy, told the New Zealand
Commission, "genetic engineering technology, as it's being applied in agriculture now, [is] based on the understanding of genetics we had 15 years ago, about genes being isolated little units that work independently of each other." He explained that genes actually "work as an integrated whole of families." In 2003, Antoniou represented non-governmental organizations on the UK's supposedly balanced GM Science Review Panel that was part of the nationwide "GM Nation?" public debate." - Jeffrey M. Smith, Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods (Get the book.)
"To confound the issue, some defend GM crops by claiming that we need genetic engineering for human gene therapy or to produce medicine such as GM insulin for diabetics. This falsely implies that to be against GM crops one must necessarily be against other forms of genetic engineering.
Personal attack. When authors or scientists are personally attacked, it can signify that they have a particularly strong argument or evidence that can damage the industry position."
- Jeffrey M. Smith, Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods (Get the book.)
| "Meanwhile, a study published in the Journal ofNeuroscience in March 2003 showed that levels of neprilysin, a beta-amyloid-degrading enzyme, could be boosted by means of gene therapy. This caused a reduction in the plaque found in the brains of the animal subjects. Another study, published in Nature Medicine, was conducted that pointed to astrocytes, naturally occurring cells that protect neurons, as mechanisms that counter beta-amyloid. Researchers theorize that defects in the ability of astrocytes to clear beta-amyloid could be a contributing factor in plaque development." - Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)
"Retinal cell transplantation and gene therapy are still in the preliminary stages of research, but both may prove to be effective in treating retinitis pigmentosa. Photoreceptor cells have been transplanted successfully into the retinas of animals. The Foundation Fighting Blindness reports that it remains to be seen whether or not this procedure will be effective with retinitis pigmentosa-type disorders. Meanwhile, researchers have identified many of the mutated genes that contribute to the condition."
- Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)
| "There is a tremendous amount of enthusiasm out there for genetic testing and gene therapy. Some of this is perfectly understandable: fantastic things are being learned. But there is also a fair amount of irrational exuberance, and maybe even a little self-promotion. Given the hoopla, a casual observer could be forgiven for thinking that knowledge about the human genome has put us on the verge of winning the war on cancer. The reality is, it has been a war we have been on the verge of winning for some 30 years. We have made progress, but progress comes slowly." - H. Gilbert Welch M.D. M.P.H., Should I Be Tested for Cancer? Maybe Not and Here's Why (Get the book.)
"Since this is a book about cancer testing, I will confine my comments
to genetic testing and avoid gene therapy. First, though, let me define my terms. Genetic testing really involves the search for various molecules?not just genes per se, but also the molecules that the genes code for (called gene products). And there are really two very different settings for such molecular testing: testing healthy people to better characterize their risk of cancer, on the one hand, and testing people who already have cancer to better characterize the cancer, on the other."
- H. Gilbert Welch M.D. M.P.H., Should I Be Tested for Cancer? Maybe Not and Here's Why (Get the book.)
| "There are two types of gene therapy. Somatic gene therapy corrects a problem in a particular patient, but these corrections are not inherited by the next generation. This is the type of therapy that is being researched today. The second type is called germline (egg or sperm) gene therapy, and this involves modification of cells that will be passed on to the next generation. Due to technical and ethical reasons, this type of therapy is not currently being studied." - Garcia Oz, Sharyn Kolberg, The Healthy High-tech Body (Get the book.)
| "As part of this gene therapy, work is proceeding with vector aerosols. A vector is like a shuttle that can deliver a good copy of the defective gene to the appropriate place in the body.
01 The drug amiloride (Midamor, Moduretic), which is used as an adjunct to treatment with some diuretic drugs, is being tested as a treatment for CF. It is believed to thin lung secretions by blocking sodium uptake by lung cells.
01 DNAase (Dornase) is a naturally occurring enzyme that breaks down DNA molecules." - Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)
| "Today physicians prescribe exercise and the Atkins or South Beach diet; it is possible that in the future there could be medical interventions in the genes (assuming they can be identified) that recognize satiation. gene therapy has not yet succeeded for many problems, but one can imagine the rush to
genetic doctors if there were a way to manipulate genes to control one's weight. We know that baldness often has a genetic basis, and with Rogaine and hair transplants it has already begun to be medicalized." - Peter Conrad, The Medicalization of Society: On the Transformation of Human Conditions into Treatable Disorders (Get the book.)
| "The gene therapy and Therapeutics Branch of the National Institute of Dental and Craniofacial Research is currently studying this important question by investigating the potential use of gene therapy in modulating inflammation and halting destruction occurring in salivary glands. The focus is directed upon insetting molecules (as cytokines) into salivary glands that will subsequently aid in maintaining the gland's functionality. Also, the capacity to produce molecules that enhance saliva production by residual salivary gland cells might be introduced by gene transfer." - The Life Extension Editorial Staff, Disease Prevention and Treatment (Get the book.)
"Another drug, PEGASYS, is undergoing Phase III clinical trials, awaiting approval by the FDA.
• gene therapy as a treatment option is the subject of research, but even if research indicates that gene therapy appeats feasible, human trials are years away.
Itching is a very troublesome symptom for patients with liver disease. It is also a very difficult symptom to manage for physicians. The reason why patients with liver disease itch is not understood. One thought is that certain substances accumulate in the blood as a result of liver disease and cause itching."
- The Life Extension Editorial Staff, Disease Prevention and Treatment (Get the book.)
"Can genes, considered by some to be contributing factors of SS, also prove curative? The gene therapy and Therapeutics Branch of the National Institute of Dental and Craniofacial Research is currently studying this important question by investigating the potential use of gene therapy in modulating inflammation and halting destruction occurring in salivary glands. The focus is directed upon insetting molecules (as cytokines) into salivary glands that will subsequently aid in maintaining the gland's functionality."
- The Life Extension Editorial Staff, Disease Prevention and Treatment (Get the book.)
"Gene therapy as a treatment option is the subject of research, but even if research indicates that gene therapy appeats feasible, human trials are years away.
Itching is a very troublesome symptom for patients with liver disease. It is also a very difficult symptom to manage for physicians. The reason why patients with liver disease itch is not understood. One thought is that certain substances accumulate in the blood as a result of liver disease and cause itching. The nature of these substances is under investigation, but some evidence suggests that normal substances found in blood plasma (e."
- The Life Extension Editorial Staff, Disease Prevention and Treatment (Get the book.)
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