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"But in the past decade or so, more research has led to a better understanding of synergy that exists between nutritional components, and along the way this research has revealed quite a bit about the power of whole foods and dietary patterns. And now that a true picture of nutrition is starting to take shape, it seems there is a lot more to the story. " - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)

"Wine may not be the X factor in the French or Mediterranean diet, but it does seem to be an integral part of those dietary patterns. There is now abundant scientific evidence for the health benefits of alcohol to go with a few centuries of traditional belief and anecdotal evidence. Mindful of the social and health effects of alcoholism, public health authorities are loath to recommend drinking, but the fact is that people who drink moderately and regularly live longer and suffer considerably less heart disease than teetotalers." - Michael Pollan, In Defense of Food: An Eater's Manifesto (Get the book.) "In recent years a less reductive method of doing nutritional science has emerged, based on the idea of studying whole dietary patterns instead of individual foods or nutrients. The early results have tended to support the idea that traditional diets do indeed protect us from chronic disease and that these diets can be transferred from one place and population to another." - Michael Pollan, In Defense of Food: An Eater's Manifesto (Get the book.) "Prospective Study of Major dietary patterns and Risk of Coronary Heart Disease in Men," American Journal of Clinical Nutrition, 2000; 72:912-21. gests is that the addition of certain foods to the diet (Vegetables and fruits? Whole grains? Garlic?) may be more important than the subtraction of the usual nutritional suspects.* As the authors of the first study point out, the strength of such an approach is that "it more closely parallels the real world" in that "it can take into account complicated interactions among nutrients and non-nutrient substances in studies of free-living people." - Michael Pollan, In Defense of Food: An Eater's Manifesto (Get the book.) "A Clinical Trial of the Effects of dietary patterns on Blood Pressure," New England Journal of Medicine, Vol. 336, No. 16, April 17, 1997.) Neither of these studies relied on food-frequency questionnaires; rather, the researchers prepared the meals for the participants. The Lyon Diet Heart Study found that the Mediterranean diet, when compared to a Western diet, offered protection against a second heart attack during the four years patients were followed. (Michel de Lorgeril et al." - Michael Pollan, In Defense of Food: An Eater's Manifesto (Get the book.)

"In 1997 the dash collaborative research group published a trial on the effects of dietary patterns on blood pressure. Nearly 500 normal adults were enrolled. For three weeks they were fed an average American diet, low in fruits and vegetables. For the next eight weeks they were randomized to continue the control diet, eat a diet rich in fruits and vegetables, or eat a diet rich in fruits and vegetables but reduced in saturated and total fats. Sodium intake and body weight were maintained at constant levels." - Nortin M. Hadler MD, Worried Sick: A Prescription for Health in an Overtreated America (Get the book.)

"The original DASH study followed 459 participants with three dietary patterns for 8 weeks. It was designed to measure the impact of different combinations of fiber, key minerals (calcium, magnesium, and potassium), and macronutrients (protein, fat, saturated fat, polyunsaturated fat, and monounsaturated fat) on participants. A second round of research used the same diet (if it ain't broke, don't fix it, right?" - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)

"Empirically derived dietary patterns and risk of postmenopausal breast cancer in a large prospective cohort study. Am J Clin Nutr. 2005 Dec;82(6):1308-1319. Blackberries www.oregon-berries.com Ding M et al. Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity. / Biol Chem. 2006 Jun 23;281(25):17359-17368. Feng R, Bowman LL, Lu Y, Leonard SS, Shi X, liang BH, Castranova V, Vallyathan V, Ding M. Blackberry extracts inhibit activation protein 1 activation and cell transformation by perturbing mitogenic signaling pathway." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"Chapter 6 Mediterranean Magic and Other dietary patterns with Synergy One day soon I'm going to get to Italy (one of the countries I have been dying to visit even before I discovered the joy of pasta). And when I do, you can bet I'm going to experience Italian cuisine to its fullest—enjoying every dip of my bread in rich, delicious olive oil and savoring every spoonful of slow-cooked marinara. Of course, before we can begin to appreciate the way another culture approaches food, it helps to take a look at our own habits." - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)

"Dietary patterns and survival after breast cancer diagnosis. J. Clin. Oncol. 23, 9295-9303. 208. Chlebowski, R. T., Blackburn, G. L., Buzzard, I. M., et al. (1993). Adherence to a dietary fat intake reduction program in postmenopausal women receiving therapy for early breast cancer. The Women's Intervention Nutrition Study. J. Clin. Oncol. 11, 2072-2080. 209. Chlebowski, R. T., Blackburn, G. L., Thomson, C. A., et al. (2006). Dietary fat reduction and breast cancer outcome: Interim efficacy results from the Women's Intervention Nutrition Study. J. Natl. Cancer Inst. 98, 1767-1776. 210." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.) "Dietary Composition In ecologic studies, a fivefold difference in breast cancer mortality rates has been observed across countries, and dietary patterns are a major aspect of the environmental exposures that differ across these countries [100, 101]. Also, risk for breast cancer increases on relocation from low-risk countries to high-risk countries, concurrent with the adoption of the dietary and lifestyle patterns of the new locale [101-104]." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.) "In addition to the ovarian steroids, other growth factors and mitogens influenced by nutritional factors and dietary patterns also appear to play an important role in the initiation and promotion of breast cancer. Two factors that are currently of intense scientific interest are insulin and insulin-like growth factor 1 (IGF-1), and the interactions of these factors with adiposity and weight gain [8-12]." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.) "Plasma carotenoids provide a good example of the use of biomarkers as a dietary indicator when the goal is to assess and monitor dietary patterns. Vegetables and fruits contribute the vast majority of carotenoids in the diet, and plasma carotenoid concentrations have been shown to be useful biomarkers of vegetable and fruit intakes in cross-sectional descriptive studies, controlled feeding studies, and clinical trials [25-28]." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"I asked her what she was eating and it turned out that there were a number of dietary patterns that were contributing to her emotional state. I took a careful history which revealed that, while she wasn't overeating, she had developed the habit of drinking coffee and eating sweets to counter fatigue. Not only did this cause her to gain weight, but the coffee and sweets induced a hypoglycemic cycle. Her blood sugar levels were irregular, and this caused her to feel anxious." - Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)

"A major twelve-year study at Harvard University of 42,500 male health professionals ages 40 to 75 who did not initially have diabetes, cardiovascular disease, or cancer found two dietary patterns. One diet was characterized as prudent, with medium to higher concentrations of vegetables, fruit, fish, poultry, and whole grains. The other, characterized as Western, had a high consumption of red meat, processed foods, fat, dairy products, refined grains, sweets, and desserts. The researchers found that the Western dietary pattern was associated with substantially increased risk of Type-2 diabetes." - Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.) "With the energy released by this understanding comes the determination to change our lifestyle, our dietary patterns, to achieve this result. The mythology supported by the allopathic treatment approach, which has indeed not been particularly successful, is that diabetes is a one-way, downhill road to death involving multiple complications. The statistics show that diabetes as currently treated will take off 10-19 years from a person's life." - Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.)

"In an observational study, investigators examined the relationship between the dietary patterns of more than 1,000 people who had been treated for stage III colon cancer and their risk of colon cancer recurrence. The researchers found that those who followed a typical American diet were three times more likely to experience a recurrence of colon cancer than their counterparts who followed a mostly vegetarian diet, and they also were more likely to die." - Andreas Moritz, Cancer Is Not A Disease - It's A Survival Mechanism (Get the book.)

"Then, chapter by chapter, we'll discover all the amazing suspected and known examples of food synergy, starting with vitamins and minerals, then phytochemicals, whole foods, food combinations, and food synergy within specific dietary patterns. In Chapter 7, we'll discuss how what we now know about food synergy can help us prevent the top diseases. And just in case your head is swimming with too many examples of food synergy, I've condensed the discussion in the previous five chapters into a section called "Achieving Food Synergy: 12 Rules to Live By." - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)

"The three randomized controlled trials of lifestyle interventions I discuss are by Appel and colleagues, "A Clinical Trial of the Effects of dietary patterns on Blood Pressure" (1997); Tuomilehto and colleagues, "Prevention of Type 2 Diabetes Mellitus by Changes in Lifestyle" (2001); and the Diabetes Prevention Program Research Group, "Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention" (2002). The observational study of survival benefit of adhering to the Mediterranean diet in Greece is by Trichopoulou and colleagues, "Adherence to a Mediterranean Diet" (2003)." - Nortin M. Hadler, The Last Well Person: How to Stay Well Despite the Health-Care System (Get the book.) "In 1997 the dash collaborative research group published a trial on the effects of dietary patterns on blood pressure. Nearly 500 normal adults were enrolled. For three weeks they were fed an average American diet, low in fruits and vegetables. For the next eight weeks they were randomized to continue the control diet, eat a diet rich in fruits and vegetables, or a diet rich in fruits and vegetables but reduced in saturated and total fats. Sodium intake and body weight were maintained at constant levels." - Nortin M. Hadler, The Last Well Person: How to Stay Well Despite the Health-Care System (Get the book.)

"The guidelines also tend to deal with single nutrients or foods, not dietary patterns. Although you may feel as though advice about nutrition is constantly changing, the basic ideas behind my four precepts have not changed in half a century. And they leave plenty of room for enjoying the pleasures of food. To take them one by one: Eat less means eating fewer calories." - Marion Nestle, What to Eat (Get the book.) "Single nutrients and foods are easier to talk about than messy dietary patterns. And they are much easier to study. But you are better off paying attention to your overall dietary pattern than worrying about whether any one single food is better for you than another. THE BASICS OF DIET AND HEALTH Tai The basic principles of good diets are so simple that I can summarize them in just ten words: eat less, move more, eat lots of fruits and vegetables. For additional clarification, a five-word modifier helps: go easy on junk foods." - Marion Nestle, What to Eat (Get the book.)

"Eggs May Protect Against Breast Cancer Eating eggs was one of two major dietary patterns found in one recent study to be protective against breast cancer. Recently (January 2005), a study was published in Cancer Epidemiology Biomarkers and Prevention that took note of the difference in breast cancer incidence in Chinese women as they migrate from China to Hong Kong to the United States—their incidence of breast cancer more than doubles." - Jonny Bowden, Ph.D., C.N.S., The 150 Healthiest Foods on Earth: The Surprising, Unbiased Truth About What You Should Eat and Why (Get the book.)

"In spite of enzymatic mutations, amongst all the races, no "macroevolutionary" change has occurred to the human digestive organs (the teeth have not sharpened, the bowels have not de-sulcified and shortened, the liver has not enlarged), even in spite of humanity's recent history of chaotic dietary patterns. Different races and blood types display patterns of enzyme mutations allowing certain groups to metabolize certain foods, while other groups lack those enzymes. This understanding underlies the blood-type theory." - David Wolfe, The Sunfood Diet Success System (Get the book.)

"Outcomes of a Field Trial to Improve Children's dietary patterns and Physical Activity: The Child and Adolescent Trial for Cardiovascular Health (CATCH)." JAMA 275, no. 10 (1996): 768-76. McGinnis, Marianne. "Hold the Sugar: Kids Are Consuming Way More Than Is Healthy." Prevention, January 2005. Nader, P. R., E. J. Stone, L. A. Lytle, C. L. Perry, S. K. Osganian, S. Kelder, L. S. Webber, J. P. Elder, D. Montgomery, H. A. Feldman, M. Wu, C. Johnson, G. S. Parcel, and R. V. Luepker. "Three-Year Maintenance of Improved Diet and Physical Activity: The CATCH Cohort." - Connie Bennett, C.H.H.C. with Stephen T. Sinatra, M.D., Sugar Shock!: How Sweets and Simple Carbs Can Derail Your Life-- and How YouCan Get Back on Track (Get the book.)

"As people gain weight, their risk of developing prediabetes and diabetes shoots up because these conditions result from the same dietary patterns. In every case, the dramatic increase in overweight and diabetes follows the adoption of Western dietary habits, such as overeating cheap foods that are loaded with calories from sugars, sugarlike carbs, and trans fats. (Sugarlike carbohydrates mean refined carbs, usually grains, which are digested almost as quickly as sugars, leading to rapid jumps in blood-sugar and insulin levels." - Jack Challem, Stop Prediabetes Now: The Ultimate Plan to Lose Weight and Prevent Diabetes (Get the book.)

"Hu and Professor Willett: Although we agree that overall dietary patterns are also important in determining disease risk (ref. cited), we believe that identification of associations with individual nutrients should be the first step because it is the specific compounds or groups of compounds that are fundamentally related to the [disease process]. Specific components of diet can be modified, and individuals and the food industry are actively doing so. Understanding the health effects of specific dietary changes, which Campbell refers to as "reductionism," is therefore an important undertaking." - T. Colin Campbell, Ph.D. and Thomas M. Campbell II, The China Study: The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications for Diet, Weight Loss and Long-term Health (Get the book.) "Perhaps the most rewarding finding, ironically, was the demonstration that tinkering with one nutrient at a time, while maintaining the same overall dietary patterns, does not lead to better health or to better health information. Yet Harvard researchers have been steadily cranking out their findings, despite these challenges. From their slew of studies, here are some findings that I would consider as very troubling contradictions when comparing disease risks for men versus women: • Men who consume alcohol three or four times a week have a lower heart attack risk." - T. Colin Campbell, Ph.D. and Thomas M. Campbell II, The China Study: The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications for Diet, Weight Loss and Long-term Health (Get the book.) "NIH 2004 ESTIMATED FUNDING FOR DIFFERENT HEALTH TOPICS17 We won't be hearing about exciting research on dietary patterns, nor will there be serious efforts to tell the public how diet affects health. Instead, the prevention and nutrition budgets will be designated for developing drugs and nutrient supplements." - T. Colin Campbell, Ph.D. and Thomas M. Campbell II, The China Study: The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications for Diet, Weight Loss and Long-term Health (Get the book.) "In fact, if the Nurses' Health Study shows nothing else, it demonstrates that modifying the intake of one nutrient at a time, without questioning whole dietary patterns, does not confer significant health benefits. Women who tinker with fat, while maintaining a near-carnivorous diet, do not have a lower breast cancer risk. This gets to the heart of reductionism in science. As long as scientists study highly isolated chemicals and food components, and take the information out of context to make sweeping assumptions about complex diet and disease relationships, confusion will result." - T. Colin Campbell, Ph.D. and Thomas M. Campbell II, The China Study: The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications for Diet, Weight Loss and Long-term Health (Get the book.)

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