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Quotes about Coenzyme from the world's top natural health / natural living authors

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"Studies of coenzyme Q10 supplementation, however, have shown only modest changes in heart function, with no effect on what we care most about, which is prevention of heart attacks. CHOLESTIN Cholestin is an ancient remedy that has been used in Chinese medicine for centuries for the treatment of heart problems. Derived from yeast on red rice, it is called red rice yeast extract. It has eight statin compounds that are HMG coenzymeA reductase inhibitors, just like statins, that have been shown to reduce cholesterol." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Co-Energizing If you're looking for a natural way to erase the effects of occasional fatigue, you might try using CoQIO (sometimes called coenzyme Q) to boost your energy by stimulating the action of enzymes in the bloodstream. As a coenzyme, CoQIO is not an enzyme by itself. It is a natural substance found in most foods, and in many B-complex vitamins. It is thought to energize the heart muscle a bit, and may thus help improve its capacity. The result: Better blood flow and more energy. The usual dose is 30 to 100 mg per day. CoQIO is widely available in health food shops." - Bottom Line Books, Uncommon Cures For Everyday Ailments (Get the book.)

"Food sources: fish high in omega-3 fatty acids include tuna, salmon, sardines, mackerel, and herring (see precautions in text); other sources include flaxseed, hemp seeds, sunflower seeds, walnuts, almonds, and filberts Coenzyme Q10. coenzyme Q10 is a fat-soluble quinone occurring in the mitochondria of every cell that is a cofactor in the electron transport chain on which most cellular functions rely, making it essential for the health of virtually all human tissues. Plasma levels of this enzyme rise during normal pregnancy, reaching highs of 50 percent above normal by the 36th week." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"Bracts as a coenzyme whose job is primarily connected to the methy-lation process needed for the production of phosphatidylcholine, myelin, melatonin, catecholamines, DNA, RNA, cysteine, and normal red blood cells. Several forms of active B[2 work as coenzymes in the body: adeno-sylcobalamin, methylcobalamin, cyancobalamin (found in supplements and fortified foods because it is the most stable form of B12), and hydrox-ocobalamin. There are many natural Bu analogues in food, but they do not work as active coenzymes in the body and may actually block the active B[2 coenzyme function." - Gabriel Cousens, M.D., Spiritual Nutrition: Six Foundations for Spiritual Life and the Awakening of Kundalini (Get the book.)

"Biotin coenzyme forms are: Acetyl-CoA carboxylase helps make fatty acids Pyruvate carboxylase helps make blood sugar from fats and protein Methylcrotonyl-CoA carboxylase helps metabolize the amino acid leucine Propionyl-CoA carboxylase helps burn fats Biotin is needed to make energy in the mitochondria of the cell as shown in Figure 1-11. Biotin may also play a role in the transcription and replication of DNA. Acetyl-CoA is a central step in the production of energy in the cell." - Dr. Steve Blake, Vitamins and Minerals Demystified (Get the book.)

"Sinatra put Joe on a multivitamin, mineral, and antioxidant supplement program, and then on coenzyme Q10 (CoQIO). In 1987, Joe had another angiogram because of recalcitrant chest pains. One of the coronary arteries showed no progression of disease, another showed regression, and another some progression. From a physician's perspective, it was phenomenal that Joe was still alive, let 1 alone doing this well. Sixty percent of people in his condition die within five years. Clearly, the disease was more stable, but the progression in one vessel indicated he still needed help." - Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.) "Technically, they are HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitors, meaning they reduce the action of the principal enzyme in the liver that produces cholesterol. The targeted medical effect is to decrease LDL cholesterol. We use statins extensively but selectively in our practices. They have definite therapeutic value, but they also have definite downsides. They are too often inappropriately prescribed by physicians solely preoccupied with cholesterol." - Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)

"Degradation: easily destroyed by heat. coenzyme forms: ThiaminPyroPhosphate (TPP), Thiamin Triphosphate (TTP). deficiency can lead to an enlarged heart, weight loss, muscular weakness, poor short-term memory, and cardiac failure. If thiamin is absent or too low in the diet for prolonged periods, this can result in beriberi. Beriberi can result from the consumption of unfortified refined grains such as white flour. Beriberi can cause damage to the nervous system, heart, and muscles." - Dr. Steve Blake, Vitamins and Minerals Demystified (Get the book.) "Vitamin B6 is needed by a coenzyme that helps release blood sugar from glycogen (stored blood sugar). Only 13 percent of the Vitamin B6 in whole wheat remains after it is refined into white flour. White rice contains only 34 percent of the vitamin B6 present in brown rice. Vitamin B6 is not normally added back to grains during enrichment. Unfortunately, the vitamin B6 content of other common carbohydrates, such as sugar, high fructose corn syrup, and alcohol is very low. Without enough vitamin B6, it is more difficult to burn carbohydrates." - Dr. Steve Blake, Vitamins and Minerals Demystified (Get the book.) "Forms in the body: found in glutathione, coenzyme A, methionine, cysteine, and SAMe. Summary for Iron Main functions: transportation of oxygen and energy metabolism. RDA: adults, 7 to 18 mg; pregnant women, 27 mg. Toxicity: only with a genetic disorder. Digestive discomfort may occur if taken on an empty stomach. Tolerable upper intake level is set at 45 mg. 40 mg for ages under 14. Deficiency can cause fatigue and anemia. Deficiency is common. Sources: meat, fish, poultry, green leafy vegetables, dried fruit, blackstrap molasses, nuts and seeds, and fortified grains." - Dr. Steve Blake, Vitamins and Minerals Demystified (Get the book.)

"Rotate antioxidants (use a bottle of one or two, and vary throughout the year) such as lipoic acid (200 mg/day), coenzyme Q10 (100 to 200 mg/day), vitamin C (1,000 to 2,000 mg/day), green tea extract, and NAC (N-acetylcysteine) (1,000 to 1,500 mg/day). Ensure that you are taking enough magnesium and B vitamins, particularly B6, B12, and folic acid. Request genetic testing to see if you have inherited problems breaking down estrogen, or problems with inflammation, clotting, or bone loss. Certain vitamins can be given to improve inherited metabolic problems." - Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

"Even a high quality methylated vitamin (one that uses the coenzyme of the vitamin), is stripped off these agents and can trigger an imbalanced response by the body, such irritation and removing existing vitamins (thereby causing a vitamin deficiency). For detailed information about the "Hidden Perils of Vitamin Pills," see Chapter 14 of Timeless Secrets of Health and Rejuvenation. Grilling meat, poultry or fish: In April 2008 the American Institute of Cancer Research urged everyone to rethink the pastime of barbecuing meat." - Andreas Moritz, Cancer Is Not A Disease - It's A Survival Mechanism (Get the book.)

"Vitamin D. coenzyme Q-10. Transfer factor. Selenium. Iron. Chromium. Multiple vitamin/mineral. Tier Three Supplements N-acetyl-carnitine. ? DMAE. • Silymarin. • 5-HTP. Activated charcoal. Pantothenic acid (vitamin B-5). Phosphatidylcholine. Oral gamma globulin. Pycnogenol. Other herbal preparations, including: Quercitin. • Curcumin. • Oregano oil. Caprylic acid. Olive leaf extract Garlic. Lauricidin. Creatine. Carnosine. • SAMe." - Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.)

"Although coenzyme Q10 represents one of the greatest breakthroughs for the treatment of cardiovascular disease as well as for other diseases, the resistance of the medical profession to using this essential nutrient represents one of the greatest potential tragedies in medicine," says my friend, board-certified cardiologist, nutritionist, and noted author Stephen Sinatra, M.D. CoQ 10 has been an approved drug in Japan for congestive heart failure since 1974. And several studies have demonstrated a relationship between depleted CoQ 10 levels and heart disease. So What Is CoQ10, Anyway?" - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Effect of dietary coenzyme Q10 as an antioxidant in human plasma. Mo IAspects Med 1994; 15 Suppls:97-102. Wright E Jr. et al. Oxidative stress in type 2 diabetes: The role of fasting and postprandial glycaemia. Int J Clin Pract 2006 Mar; 60(3):308-l4. Wu S, Ren J. Benfotiamine alleviates diabetes-induced cerebral oxidative damage independent of advanced glycation end-product, tissue factor and TNF-alpha. Neurosci Lett 2006 Feb 13; 394(2):158-62. Xie JT et al. Antihyperglycemic effects of total ginsenosides from leaves and stem of Panax ginseng. Acta Pharmacol Sin 2005 Sep; 26(9): 1104-10." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"But several elements of the program stood out, and it's those three elements that form the core of our combo cure for hypertension: the DASH diet, coenzyme Q10, and hydrolyzed whey protein. The DASH Diet In 1997, the National Heart, Lung and Blood Institute funded research on the effects on blood pressure of groups of nutrients as they're found together in foods. The name of this study was Dietary Approaches to Stop Hypertension, or DASH, for short." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.) "Now Add in the Combos: Three Nutrients, Two Herbs Riboflavin (vitamin B2), magnesium, and coenzyme Q10 (CoQIO) have been researched, reviewed, and studied for their effectiveness in managing migraines. They are all good, effective alternative treatments and can help to prevent migraines. CQ10 is a nutrient that is normally associated with energy: It helps the cells utilize oxygen. Andrew Hershey, M.D., Ph.D., associate director of neurology research at Cincinnati Children's Hospital Medical Center, looked at its relation to migraine in a recent study done at the University of Cincinnati." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Vitamin B-12 (Cobalamin) Vitamin B-12 is involved in numerous biochemical reactions as a cofactor and coenzyme. Its main functions involve DNA synthesis, methionine synthesis from homocysteine, and conversion of propionyl into succinyl coenzyme A from methylmalonate. The psychiatric manifestations of a vitamin B-12 deficiency include agitation or restlessness, dementia, depression, fatigue, irritability, panic and phobic disorders, personality change, psychosis, mild memory impairment, and negativism." - Abram Hoffer, PhD, MD, FRCP(C) and Dr. Jonathan Prousjy, DPHE, DSC, ND, FRSH, Naturopathic Nutrition: A Guide to Nutrient-rich Food & Nutritional Supplements for Optimum Health (Get the book.)

"Combination treatment with coenzyme Q10 and simvastatin in patients with coronary atherosclerosis." Kardiologiia. 2006;46(8):11-3. Sander, S.; Coleman, C.I.; Patel, A.A.; Kluger, J.; White, CM. "The impact of coenzyme Q10 on systolic function in patients with chronic heart failure." J Card Fail. 2006 Aug;12(6):464-72. University of Connecticut School of Pharmacy, Storrs, Connecticut 06269, USA. Tuekpe, M.K.; Todoriki, H.; Sasaki, S.; Zheng, K.C.; Ariizumi, M. " - Jan Lovejoy, Get Balanced-the Natural Way to Better Health with Superfoods (Get the book.)

"Several randomized controlled trials reported a reduced frequency of cardiovascular events and an improved lipid profile when niacin was taken alone or in combination with statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) [251-255]. Of note in the study by Brown et al., however, was the inclusion of the "antioxidant cocktail" (800 IU vitamin E, 1000 mg vitamin C, 25 mg (3-carotene, and 100 pg selenium) with drug therapy. The antioxidants blunted the effect of simvastatin/niacin treatment and did not reduce stenosis progression, unlike the simvastatin/ niacin treatment." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"Daily Supplementation Dandelion leaf capsules: 2 capsules daily Garlic: 1 capsule containing 4,000-5,000 meg allicin, twice per day coenzyme Q10: 100 mg per day Potassium: 99 mg-2.5 g per day Herbal tincture: Motherwort: 2 oz Passionflower: 2 oz Rauwolfia (available through health-care practitioner—not to exceed .3 mg of reserpine per day) Hawthorne: 2 oz Dose: 1 tsp twice daily • "Data from studies such as the WHI and the Heart and Estrogen/progestin Replacement Study (HERS) should be extrapolated only with caution to women younger than 50 years of age who initiate HT." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.) "Pantethine is the activated form of vitamin B5 (pantothenic acid) and a key component of coenzyme A (CoA). CoA plays a significant role in lipid metabolism and is involved in the transport of fats. The cells of our body need CoA to utilize fats in the form of energy. Pantethine, at the typical dose of 300 mg three times per day, has been shown to significantly reduce serum triglycerides, total cholesterol, and LDL cholesterol, while also increasing HDL cholesterol.243, 244 This same dose was found to be effective at decreasing adverse lipid parameters in postmenopausal women." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"DFR requires NADPH as a coenzyme and DFR overexpression results in increased NAD activity and transcription. This in turn alters NAD oxidation state, subsequent changes in activity, and NAD homeostasis (Hayashi et al, 2005). Although this is not a direct flavonoid target, the feedback Figure 4.1 Figure 5.2 Figure 5.3 Figure 5.4 r 1 * o 0 © ¦ o e | 1 0 ¦ Set Figure 6." - Erich Grotewold, The Science of Flavonoids (Get the book.) "Cloning, nucleotide sequence and expression of the Escherichi coli fabD gene, encoding malonyl coenzyme A-acyl carrier protein transacylase, JBact 174: 2851-2857. Watt, W. B., 1977, Adaptation at specific loci 1. Natural selection on phosphoglucose isomerase of Colias butterflies—biochemical and population aspects, Genetics 87: 177-194. Watt, W.B, 1983, Adaptation at specific loci. 2. Demographic and biochemical-elements in the maintenance of the Colias PG1 polymorphism, Genetics 103: 691-724. Webby, R. F., MarkJiam, K. R., and Smith, R. I. L." - Erich Grotewold, The Science of Flavonoids (Get the book.)

"In another study, 3 g of taurine outperformed even coenzyme Q10, another superb nutrient with documented results in congestive heart failure. In 1928, the New York Heart Association published a classification of cardiac patients into four functional classes (I through IV) based on their prognosis and their clinical severity (that publication is now in its ninth edition and still going strong)." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Other beneficial substances include ginkgo, which enhances circulation to the micro capillaries, oxygenating the tissues in the brain; coenzyme Q10, "a very energetic cofactor that works in the brain's power plant, the mitochondria"; and old-style phosphatidyl serine (PS) from bovine brains, as well as newer types of PS synthesized from soybeans. "Everything I've talked about is regenerating or protective, not stimulating," Dr. Khalsa says. "I stay away from compounds like DMAE and acetyl carotene because I think they are not good for everybody. They are way too stimulating." - Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)

"Two patients with advanced epithelial ovarian carcinoma (stage IIIC) received antioxidant therapy (1200 IU vitamin E, 300 mg coenzyme Q]0, 9000 mg vitamin C, 25 mg mixed carotenoids, and 10,000 IU vitamin A) before conventional chemotherapy and 60 g ascorbic acid twice weekly at the end of therapy. Both women had normal CA-125 levels and remained disease-free more than 3 years after initial diagnosis [120]." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.) "Conclusions about vitamin C and coenzyme Q were mixed. It should also be noted that their influence on cancer was not evaluated, but Taylor and Greenwald have reviewed a number of completed nutritional cancer prevention trials [14], which helps fill out the background picture. This collection of potential positive and negative antioxidant effects on ROS deserves further examination because of the molecular evidence for the multiple role(s) of ROS in development and progression of cancer, cardiovascular disease, and other diseases [2, 8]." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.) "Effects of the supplemental use of antioxidant vitamin C, vitamin E and coenzyme Q10 for the prevention and treatment of cancer. Evid. Rep. Technol. Assess. (Summ.) 75, 1-3. 14. Taylor, P. R., and Greenwald, P. (2005). Nutritional interventions in cancer prevention. J. Clin. Oncol. 23, 333-345. 15. Castro, L., and Freeman, B. A. (2001). Reactive oxygen species in human health and disease. Nutrition 17, 161, 163-165. 16. Sohal, R. S., and Weindruch, R. (1996). Oxidative stress, caloric restriction, and aging. Science 273, 59-63. 17. McCord, J. M. (2000)." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

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