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Quotes about Clinical Trials from the world's top natural health / natural living authors

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"In its significant scientific agreement guidance, the agency strongly suggested that only well-designed, large-scale, randomized, prospective, double-blind, placebo controlled clinical trials would suffice to support a claim. In its qualified health claim guidance, the agency likewise stated that it would provide less than draconian disclaimers only for those claims backed by clinical trials acceptable to the agency. By declaring treatment studies largely off limits, the FDA thus indicated that no qualified health claim would be given anything less than a draconian disclaimer." - Jonathan W. Emord, The Rise of Tyranny (Get the book.)

"Progesterone is often touted in the natural products marketplace as effective for the prevention and treatment of osteoporosis, but clinical trials show that neither oral natural progesterone nor progesterone patches or creams can slow, prevent, or reverse bone loss. I can't stress enough that if you are peri- or postmenopausal and are taking any form of estrogen, you must also take a proven form and dosage of progesterone (or progestin) to protect your uterus from hyperplasia and cancer. The exception is women who have had a hysterectomy; they do not need to take progesterone or progestins." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"C 73 m WORTH KNOWING n a m The Canadian company that sponsored the 1/1 clinical trials mentioned in this section was Neptune Technologies and Bioresources; the same kind of krill oil used in the studies is often labeled Neptune Krill Oil. In the PMS study, Neptune Krill Oil was given over the course of 90 days. With natural prescriptions for PMS, it's a good idea to give it a try over at least three cycles. true. (It got your attention though, didn't it?) But it is true that their risk for breast cancer is substantially less than sighted women, 50 percent less by some estimates." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.) "Now it probably took a bit of trial and error for the aborigines to figure out which tree leaves had this amazing property, but think of those hit-and-miss tests as the primitive version of what we now call clinical trials. But figure it out they did, and the plant they used—not just for scratches and infection and wound healing but for all manner of things that required what we now know as an antibiotic—was the tea tree." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Double-blind clinical trials have found 100 mg per day of DHEA to be effective in decreasing body fat in older men. Conversely, when the body's DHEA levels are insufficient, body fat is more difficult to budge. Recently, a female patient named Shirley complained that she had gained fifteen pounds in the last nine months. She said she wouldn't be unhappy if she could only spread some of those pounds around to her "stick-skinny legs" or to her arms or chest. The problem was that all fifteen pounds had attached themselves to her middle." - C. W. Randolph, M.D., From Belly Fat to Belly FLAT: How Your Hormones Are Adding Inches to Your Waistline and Subtracting Years from Your Life (Get the book.) "There are volumes of solid, credible clinical trials and medical studies that validate the safety and efficacy of bio-identical hormone therapies. Unfortunately, the medical research institutions and universities that publish these studies do not have the budget to hire a sales force to go out into the field to educate physicians. Consequently, most doctors continue to remain unenlightened regarding the science behind the safe treatment option of bio-identical hormones." - C. W. Randolph, M.D., From Belly Fat to Belly FLAT: How Your Hormones Are Adding Inches to Your Waistline and Subtracting Years from Your Life (Get the book.)

"Tomatoes versus lycopene in oxidative stress and carcinogenesis: conclusions from clinical trials. Eur J Clin Nutr. 2007 Mar;61(3):295-303. Bhuvaneswari V, Nagini S. Lycopene: a review of its potential as an anticancer agent. Current Medicinal Chemistry—Anti-Cancer Agents. 2005 Nov;5(6):627-635. Das S, Otani H, Maulik N, Das DK. Lycopene, tomatoes, and coronary heart disease. Free Radic Res. 2005 Apr;39(4):449-455. Dutta-Roy AK, Crosbie L, Gordon MJ. Effects of tomato extract on human platelet aggregation in vitro. Platelets. 2001 Jun;12(4):218-227." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.) "Because the science of nutrition is always progressing, I made the decision not to limit my criteria of evaluating the 101 foods to only the gold standard of human clinical trials but instead expanded it to all levels of evidence. I am a firm supporter of evidence-based nutrition but unfortunately, randomized, crossover, placebo-controlled, human trials and meta-analyses (reviews of several studies) are few and far between in the study of nutrition." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.) "He also relays that bromelain: • Reduces postoperative swelling • Helps relieve symptoms associated with sinusitis • When combined with antibiotics and trypsin (an enzyme), can also help control the symptoms of urinary tract infections • May help relieve symptoms of rheumatoid arthritis Results of several clinical trials indicate that bromelain acts as a blood-thinner and can help relieve the symptoms of angina and thrombophlebitis. CANCER PREVENTION: Cornell University food scientists found that eating pineapples reduced the formation of nitrosamines (potential carcinogens) in humans." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.) "The National Cancer Institute is conducting human clinical trials with perillyl alcohol to investigate its effectiveness in halting breast cancer. Animal studies have demonstrated positive results in regressing pancreatic, mammary, and liver tumors and may hold hope for preventing and treating many other types of cancer. ANTIBACTERIA AND FUNGI (MOLD): Celery contains polyacetylenes, substances highly toxic against fungi and bacteria. This compound also has anti-inflammatory effects and makes blood more slippery." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"But to get from where Kerr is now in his research to clinical trials "will take millions of dollars," says Kerr. "With the current political climate, it's not clear where that money will come from. We know that the federal government will not help. Drug companies are reluctant to step in because of patent issues—and because each of these diseases, taken individually, does not afflict a large enough number of patients. We go month to month hoping that something will happen with funding that will allow us to keep going." - Donna Jackson Nakazawa, The Autoimmune Epidemic (Get the book.) "Faustman hopes that by 2012 her lab will have enough data to enable them to launch multicenter clinical trials around the country. Her goal in such a wide-scale clinical trial will be to find the exact dosing that can best kill off the renegade T cells that cause type 1 diabetes in the average patient. By 2017, she says, she hopes to have a "good therapeutic window" on what would be a standard dose to cure type 1 diabetes in your local doctor's office. She smiles. "Better yet, by then I will hopefully have come up with even better ideas." - Donna Jackson Nakazawa, The Autoimmune Epidemic (Get the book.)

"However, the individual antioxidants of these foods studied in clinical trials, including ^-carotene, vitamin C, and vitamin E, do not appear to have consistent preventive effects comparable to the observed health benefits of diets rich in fruits and vegetables (Omennetal, 1996). It has been reported that fresh apples have potent antioxidant activity; and whole apple extracts inhibit the growth of colon and liver cancer cells in vitro in a dose-dependent manner (Eberhardt et al, 2000), suggesting that natural phytochemicals in fresh fruits could be more effective than a dietary supplement." - Erich Grotewold, The Science of Flavonoids (Get the book.)

"Epidemiological studies have suggested that the use of nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, naproxen, and indomethacin, may reduce the risk of AD, but clinical trials on human beings have not demonstrated a benefit. In fact, NSAIDs have been shown to cause gastrointestinal bleeding, as well as liver and kidney toxicity, which have limited their usage with the elderly. Similarly, another popular news story has been that estrogen therapies will protect the brain and slow Alzheimer's." - Peter J. Whitehouse and Daniel George, The Myth of Alzheimer's: What You Aren't Being Told About Today's Most Dreaded Diagnosis (Get the book.)

"Green Tea Green tea contains potent antioxidant and polyphenol compounds called catechins, which have been shown to enhance energy in human clinical trials, help balance glucose levels, and protect against the development of atherosclerosis. Study results suggest that the polyphenols in green tea may interfere with the absorption of cholesterol in the intestinal tract and promote its elimination from the body." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"Instead, I cited a few of the clinical trials showing that exercise is as effective as certain medications for treating anxiety and depression. Then I launched into a twenty-minute monologue about what exercise does for the brain, and, specifically, how it had tamed Amy's anxiety and allowed her to master her chaotic feelings in the nine months she'd been my patient. If it was exercise this lawyer wanted to put on trial, I was all for it." - John J. Ratey, MD, Spark: The Revolutionary New Science of Exercise and the Brain (Get the book.)

"A number of clinical trials have shown that vitamin E supplementation (alone or in combination with other antioxidants) leads to increased resistance of LDL to oxidative damage.167- 168 Doses between 500 and 1,500 IU have shown significant reduction in LDL oxidation.169 Women who took vitamin E supplements for more than two years had about half the risk of CVD.170 A recent study evaluating childhood and adulthood dietary intake of vitamin E found that people who consumed the most vitamin E in their diet had a decreased risk of hypertension." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"CONTROLLED clinical trials PREVENT SUICIDE, REGARDLESS OF THE DRUG THE FDA AND PRO-DRUG ADVISORY committee members at the hearing emphasized that there were no completed suicides in the antidepressant drug trials submitted to it by the drug companies. The FDA also promotes this misleading claim.22 When confronted with the question during a deposition against GlaxoSmithKline in early 2007,1 realized that there were no suicides in either the drug groups or the sugar pill groups." - Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"It seems to be associated with modest improvements in fasting glucose and hepatic insulin resistance. clinical trials have found a significant decrease in insulin requirements in patients with insulin-dependent diabetes after vanadyl sulfate therapy. They have also noted a decrease in cholesterol levels for both IDDM and NIDDM. It has also been found to stimulate glucose uptake and metabolism that leads to glucose normalization. In some cases it helps to restore insulin production in diabetic rats. Kelp and sea vegetables are good sources of vanadium." - Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.) "A variety of human clinical trials have established blood sugar lowering action of the fresh juice or abstract.55,56 More than 100 studies have demonstrated bitter melon's ability to decrease the blood sugar, increase the uptake of glucose, and activate the pancreatic cells that manufacture insulin. The peptide it has acts like bovine insulin. So it has several effects: improved glucose tolerance without increasing insulin levels, stimulating the beta cells of the pancreas, suppressing the urge to eat sweets, and action similar to that of insulin." - Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.)

"If any reader is laboring under the premise that science, clinical research, clinical trials, and data interpretation are not subject to the vicissitudes of realpolitik, let me disabuse you, hopefully for now and forever. The "market" for osteoporosis prevention is a promised land for Big Pharma and the equities markets. Without even a hesitation, the medical literature is rationalizing screening white and Asian women who are aging, particularly if they are thin. There is an argument that since black women have a lower fracture risk than white women at every level of bmd (Cauley et al." - Nortin M. Hadler MD, Worried Sick: A Prescription for Health in an Overtreated America (Get the book.)

"It follows that those who design clinical trials would hope for a very small placebo effect, for it only gets in the way—muddies the waters—of the "real" effect, the one they are looking for, hoping to publish, and hoping to save lives. For clinicians, then, the placebo "is tolerated as a necessary nuisance" but is otherwise "considered with contempt."20 Thus, our point: given this marginal status, the placebo effect is an unlikely beacon of light to illuminate the forest of our ignorance." - Gerald E. Markle and Frances B. McCrea, What If Medicine Disappeared? (Get the book.)

"Magnesium deficiency is now considered to contribute to many diseases, and the role for magnesium as a therapeutic agent is being tested in numerous large clinical trials. The following list describes the physiological activities of this important mineral. Possible Benefits of Magnesium in Heart Disease ?Antiarrhythmic properties ?Controls flow of calcium into the heart cell (calcium channel blocking effect) ?Improvement in LDL/HDL ratio (LDL = low-density lipoprotein cholesterol; HDL = high-density lipoprotein cholesterol) ?" - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.) "It was not until 1974 that large enough quantities of coenzyme Q10 could be harvested to support organized clinical trials in large groups of people. Scientists in Japan perfected the industrial technology to produce pure coenzyme Q10 in sufficient quantities for distribution. It was at this point that coenzyme Q10 gained widespread acceptance in Japan and became more available for those with heart disease. Meanwhile, one night, at about 3:00 A.M., English scientist Peter Mitchell was struggling to sleep. Envisioning an incomplete schema in his mind, he suddenly had an "Aha!" - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.) "We have strong scientific evidence from large and repeated clinical trials that confirm the efficacy and safety of these nutrients, as well as their potential medicinal interactions. After practicing my specialty for more than thirty-five years, I predict that the successful cardiologist of the future will be flexible, adaptable, and knowledgeable so he or she can tailor treatment approaches and select the best available options for each patient's needs." - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.) "Japanese, and later European, scientists and physicians have conducted the majority of clinical trials employing coenzyme Q10. In a 1985 review article, Dr. Yamamura listed sixty-seven clinical studies that evaluated coenzyme Qio in cases of heart muscle disease, arrhythmias, and heart damage from drugs, high blood pressure, and stroke. At the same time, Per Langsjoen, M.D., in Texas, reported on coenzyme Q10 as a valuable nutrient for cardiomyopathy in a double-blind test. Just one year later (in 1986), the prestigious Priestley Medal of the American Chemical Society was awarded to Dr." - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.)

"Given the modest symptomatic relief of current Alzheimer's drug therapies, consistently disappointing results from recent clinical trials testing new treatment candidates, and uncertainty about the potential merits of future treatments such as stem cells and beta-amyloid vaccines, governments have ample incentive to begin shaping a more nuanced policy that will focus on improving the health of entire populations over their entire life course rather than responding to cognitive decline after the fact." - Peter J. Whitehouse and Daniel George, The Myth of Alzheimer's: What You Aren't Being Told About Today's Most Dreaded Diagnosis (Get the book.)

"This had little or nothing to do with the conduct of the required clinical trials, which typically last only a few weeks in duration; it had everything to do with the useless bureaucratic hoops imposed on the companies by the FDA. In recent years, Congress has arranged for the FDA to receive funding directly from the drug companies to expedite the approval process, and the length of the approval process has been greatly shortened." - Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"When we attempt to develop therapies to keep the immune system from attacking itself, it is impossible to guess whether all other functioning parts of the immune system will remain uncompromised in the process—and only long-term clinical trials can provide the answer. All of which leaves autoimmune-disease sufferers with dicey options. The multiple sclerosis drugs Avonex, Rebif, and Betaseron can lead to rare liver problems, Copaxone can lead to severe allergic reaction." - Donna Jackson Nakazawa, The Autoimmune Epidemic (Get the book.)

"The updated guidelines rely heavily on the findings of five large clinical trials of CHD prevention with statins that had become available since the previous version of the guidelines were issued in 1993. The executive summary published in JAMA is clear about its primary approach to CHD prevention: after a brief discussion of the changes introduced in the new guidelines and the new method of individual risk assessment, the bulk of the recommendations address LDL cholesterol as "the primary target of therapy." - John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

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