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"Women with gestational diabetes whose diets were supplemented with 4 meg of chromium per kilogram of body weight daily as chromium picolinate for eight weeks had decreased fasting blood glucose and insulin levels, compared with those who took a placebo.166,167 Dosage: Niacin-bound chromiurn is more bioavailable than chromium picolinate. A recent study at the University of California found that chromium polynicotinate was absorbed and retained up to 311 percent better than chromium picolinate and 672 percent better than chromium chloride." - Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.)

"Chromium chloride is a poorly absorbed form. chromium picolinate is the form used in much of the research on the health effects of chromium and is well absorbed. Chromium nicotinate also has good bioavailability. Certain nutritional yeast products are fortified with chromium and have good bioavailability. TOXICITY OF CHROMIUM As noted above, hexavalent chromium is known to cause cancer and skin irritation. There have been no convincing reports of toxicity from the trivalent chromium in food or supplements. Therefore, the Food and Nutrition Board has not set an upper level for chromium." - Dr. Steve Blake, Vitamins and Minerals Demystified (Get the book.)

"Recently, a few scientists have expressed concern that long-term use of large doses of chromium, particularly chromium picolinate, may cause chromosomal abnormalities. That concern is based on test-tube studies that used extremely large concentrations of chromium picolinate. This problem has not actually been shown to occur in humans or experimental animals. Toxicity studies in animals have shown that chromium is remarkably safe; it has one of the lowest toxicity profiles of all the essential trace minerals." - Jonathan V. Wright, M.D. and Alan R. Gaby, M.D., Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing (Get the book.)

"In a study involving 185 adult-onset diabetic patients, there were significant decreases in the concentration of fasting and 2-hour glucose levels, insulin, hemoglobin A1C, and total cholesterol among patients supplemented with 1000 meg of chromium picolinate compared to those on 200 meg of chromium picolinate or placebo. Thus, chromium as part of the LMWCr should have the ability to improve glucose tolerance and increase insulin sensitivity in diabetic patients with poor glucose control. Depression: Taking 500 meg daily of chromium has antidepressant therapeutic properties." - Abram Hoffer, PhD, MD, FRCP(C) and Dr. Jonathan Prousjy, DPHE, DSC, ND, FRSH, Naturopathic Nutrition: A Guide to Nutrient-rich Food & Nutritional Supplements for Optimum Health (Get the book.)

"Niacin-bound chromium is more bio-available than chromium picolinate. A recent animal study at the University of California found that Chromium Polynicotinate was absorbed and retained up to 311% better than chromium picolinate and 672% better than chromium chloride. Suggested Use: As a dietary supplement, 6 sprays (in the mouth) once a day, or, for greater benefit, 3 sprays, 2 times a day; or as directed by your health care professional. Preferably taken before or after meals (either 10 minutes or more before eating or 1 hour or more after eating)." - Robert Redfern, The Miracle Enzyme Is Serrapeptase (Get the book.)

"In a study involving 185 adult-onset diabetic patients, there were significant decreases in the concentration of fasting and 2-hour glucose levels, insulin, hemoglobin A1C, and total cholesterol among patients supplemented with 1000 meg of chromium picolinate compared to those on 200 meg of chromium picolinate or placebo. Thus, chromium as part of the LMWCr should have the ability to improve glucose tolerance and increase insulin sensitivity in diabetic patients with poor glucose control. Depression: Taking 500 meg daily of chromium has antidepressant therapeutic properties." - Abram Hoffer, PhD, MD, FRCP(C) and Dr. Jonathan Prousjy, DPHE, DSC, ND, FRSH, Naturopathic Nutrition: A Guide to Nutrient-rich Food & Nutritional Supplements for Optimum Health (Get the book.)

"Martin J et al. chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care 2006 Aug; 29(8): 1826-32. McKenney J, Sica D. Prescription omega-3 fatty acids for the treatment of hypertriglyceridemia. Am J Health-System Pharm 2007; 646:595-605. Medina MC et al. Dehydtoepiandrosterone increases beta-cell mass and improves the glucose-induced insulin secretion by pancreatic islets from aged rats. FEBSLett 2006 Jan 9; 580(l):285-90. Melhem MF et al." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"A recent study at the University of California found that chromium polynicotinate was absorbed and retained up to 311 percent better than chromium picolinate and 672 percent better than chromium chloride. Generally, chromium supplementation at doses of about 200 meg/day, in a variety of forms for two to three months have been found in studies to be beneficial." - Gabriel Cousens, There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program (Get the book.)

"One study randomly assigned 180 Chinese subjects with type 2 diabetes to two doses of chromium picolinate or placebo for four months. Glucose control was improved with the higher dose of 1,000 meg/day of chromium, as were measures of blood glucose and insulin levels. This is the only controlled study of chromium, however, that showed any benefit; more controlled studies need to be done to confirm these early results. Also, the fact that this was a Chinese sample means that the results aren't necessarily valid for Americans or Europeans, since there may be differences in nutritional status (i.e." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Typical daily doAe: 400-1,000 meg of chromium picolinate or GTF chromium m ?" 1 *"M 1 "" 1 1 m!j ? m SPICE AS NICE Try mixing ground cinnamon with cottage cheese or yogurt, or stir your coffee with a cinnamon stick—just leave it in for at least 5 minutes. And no, getting your cinnamon in the form of a Cinnabon doesn't count! BENEFICIAL BACTERIA: SUPPLEMENT YOUR DIET Since you're starting to restore your body, you'd better start reinvigorating a huge (literally) contributor to the proper functioning of your body-the pounds and pounds of bacteria in your colon." - Dr. Steven R. Gundry, Dr. Gundry's Diet Evolution: Turn Off the Genes That Are Killing You - And Your Waistline - And Drop the Weight for Good (Get the book.)

"We prefer the better-absorbed forms of chromium, such as chromium picolinate, chromium aspartate, or chromium polynicotinate. The optimal intake of chromium varies from person to person. For most individuals, 200 to 500 meg per day is adequate; however, in our experience, some patients appear to need 1,000 meg per day or more. Recently, a few scientists have expressed concern that long-term use of large doses of chromium, particularly chromium picolinate, may cause chromosomal abnormalities." - Jonathan V. Wright, M.D. and Alan R. Gaby, M.D., Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing (Get the book.)

"Chromium picolinate (see page 46) does the same thing and is a great supplement to use together with a low-carb diet to help manage both blood sugar and insulin. In addition to chromium, which improves glucose tolerance, decreases fasting blood sugar, and has been shown to help insulin resistance in people with diabetes, two other supplements may be helpful. Though not normally thought of as the first nutrient you'd take for PCOS, biotin in high doses (8 to 16 mg) should be considered because it has the potential to be of great help in normalizing and lowering blood sugar." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"The researchers concluded that chromium picolinate is effective in treating atypical depression. S-Adenosyl-Methionine in Depression: A Comprehensive Review of the Literature. Papakostas GI; Alpert JE; et al. Current Psychiatry Reports, 2003 December, 5(6):460-466. SAMe is a natural supplement that is backed by 30 years of research regarding its effectiveness against depression. A Double-blind, Randomized Parallel-group, Efficacy and Safety Study of Intramuscular S-Adenosyl-L-Methionine 1,4-Butanedisulphonate (SAMe) Versus Imipramine in Patients with Major Depressive Disorder." - Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)

"Anderson himself is partial to chromium picolinate, while other experts, like Preuss, favor niacin-bound chromium (chromium polynicoti-nate or chromium nicotinate, sold under the brand name ChromeMate). There's also GTF chromium (GTF stands for glucose tolerance factor), but this is a mislabeling and a misconception; no such substance exists. Interestingly, a high-sugar and processed-food diet actually drains chromium from the body, so the paradox is that those who need it the most have the least of it. Infection, pregnancy, and stress may also reduce levels." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"In another trial, capsaicin was only a component of a combination preparation including chromium picolinate, inulin, and l-phenylalanine that was administered daily in conjunction with a 4-week diet and exercise weight-loss program [83]. The dose of capsaicin could not be determined from the report, but no effects of the supplement were observed on energy intake or body weight over the 4-week trial. Thus, the longer term trials offer little support for a measurable effect of capsaicin exposure on energy balance. However, none was adequately powered to detect a realistic effect." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"She says, "Show me where the amount of picolinate used in those hamster cell studies has any bearing whatsoever on what a human being would consume if they took chromium picolinate in the ranges we're recommending." Dr. C. Leigh Broadhurst, who worked with Dr. Richard Anderson on the development of chromium picolinate at the USDA, agrees. Others are more cautious. "I'm about 99.9 percent sure that chromium picolinate is safe," says Dr. Harry Preuss. " - Jonny Bowden, M.A., C.N.S., Living the Low Carb Life: Controlled Carbohydrate Eating for Long-Term Weight Loss (Get the book.)

"The effect of chromium picolinate and bio-tin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: A placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006 Dec; 8(6):636-43. Smith B et al. Does coffee consumption reduce the risk of type 2 diabetes in individuals with impaired glucose? Diabetes Care 2005; 29:2385-90. Song DU et al. Effect of drinking green tea on age-associated accumulation of Maillard-type fluorescence and carbonyl groups in rat aortic and skin collagen. Arch Biochem Biophys 2002 Jan 15; 397(2):424-29." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"Over the past few years, the synthetic versions of chromium, chromium picolinate and chromium polyni-cotinate, have been all the rage. They're even promoted as being "better" than 'Both negative studies evaluated a synthetic Beta Carotene. For what it's worth, almost all of the Beta Carotene on the market today is an isolated synthetic made from acetylene gas. Yummy! the original, but as it turns out, that's not entirely ttue." - Jon Barron, Lessons from The Miracle Doctors: A Step-by-Step Guide to Optimum Health and Relief from Catastrophic Illness (Get the book.) "In its natural state, chromium comes packed with a whole complex of substances called GTF (glucose tolerance factor), which, among other things, protects against diabetes. chromium picolinate and chromium polynicotinate, because they ate isolates, do not contain GTE I could go on and on giving examples, such as the B vitamins and vitamin E, where science has continually come up short in identifying the key factors that make it all work. The bottom line, though, is that in nature, vitamins do not exist in isolation; they exist in complexes. And here's a final thought for you." - Jon Barron, Lessons from The Miracle Doctors: A Step-by-Step Guide to Optimum Health and Relief from Catastrophic Illness (Get the book.)

"If feelings of depression are associated with excessive appetite, overeating, or overweight, supplements of chromium picolinate may be of particular benefit. The discovery of chromium's value in atypical depression was first published in 1999 by Malcolm McLeod, M.D., a psychiatrist at the University of North Carolina School of Medicine, Chapel Hill. Since then, further studies by McLeod and others have confirmed the effectiveness of chromium picolinate in depression that involves overeating. Take 400 meg daily or 200 meg twice daily with meals. 5-HTP." - Jack Challem, The Food-Mood Solution: All-Natural Ways to Banish Anxiety, Depression, Anger, Stress, Overeating, and Alcohol and Drug Problems--and Feel Good Again (Get the book.)

"This certainly doesn't mean that chromium alone will reverse prediabetes; however, many studies have shown that either chromium polynicotinate or chromium picolinate supplements do in fact improve insulin function and can lead to improved glucose tolerance. Based on the research, the most effective dose of chromium appears to be 1,000 meg, or 500 meg twice daily with meals. We recommend the chromium polynicotinate form, also called niacin-bound chromium, which has a strong record of safety and use in supplements, beverages, and foods. Biotin." - Jack Challem, Stop Prediabetes Now: The Ultimate Plan to Lose Weight and Prevent Diabetes (Get the book.)

"The fact is, there is no evidence that supplementing chromium picolinate, let alone any other form of chromium, has the potential to cause cancer in either animals or humans. In the United States, the National Toxicology Program investigated chromium picolinate and found no evidence of "genotoxicity" or any other ill effects. And now, even the UK's Food Standards Agency agrees that chromium is nontoxic, even in amounts ten times higher than the average 200 meg supplement." - Patrick Holford, The New Optimum Nutrition Bible (Get the book.)

"In 1997, Austrian researchers conducted a study to assess the effects of chromium yeast and chromium picolinate on lean body mass during and after weight reduction with a very low-calorie diet: 36 obese nondiabetic patients undergoing an 8-week, very low-calorie diet followed by an 18-week maintenance period were evaluated. During the 26-week treatment period, study subjects received either placebo or chromium yeast (200 meg/day) or chromium picolinate (200 meg/day) in a double-blind manner. After 26 weeks, chromium picolinate-supplemented subjects showed increased lean body mass." - The Life Extension Editorial Staff, Disease Prevention and Treatment (Get the book.)

"The two leading forms of this mineral are chromium polynicotinate and chromium picolinate, and both forms have been extensively tested in people. It's often difficult to sort through the competitive claims and counterclaims for these products; however, we are impressed by the research of Harry Preuss, M.D., of Georgetown University, who found that the chromium polynicotinate form promotes fat loss but preserves muscle. Some research also suggests that chromium polynicotinate is better absorbed than other forms." - Jack Challem, Stop Prediabetes Now: The Ultimate Plan to Lose Weight and Prevent Diabetes (Get the book.)

"Whether these problems were caused by chromium picolinate or, if so, whether other forms of chromium might have the same effects at these high amounts remains unclear. No one should take more than 300 meg per day of chromium without the supervision of a doctor. Preliminary research has found that vitamin C (page 604) increases the absorption of chromium.19 COCONUT OIL What is it? Coconut oil is a member of the family of tropical oils, which also include palm, palm kernel, cocoa, and shea nut oils." - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"During the 26-week treatment period, study subjects received either placebo or chromium yeast (200 meg/day) or chromium picolinate (200 meg/day) in a double-blind manner. After 26 weeks, chromium picolinate-supplemented subjects showed increased lean body mass. Researchers reported chromium picolinate, but not chromium yeast, is able to increase lean body mass in obese patients in the maintenance period after a very-low-calorie diet without counteracting the weight loss achieved (Bahadori et al. 1997)." - The Life Extension Editorial Staff, Disease Prevention and Treatment (Get the book.)

"However, other studies have failed to show a significant effect of chromium picolinate on body composition.9 Where is it found? The best source of chromium is true brewer's yeast (page 480). Nutritional yeast and torula yeast do not contain significant amounts of chromium and are not suitable substitutes for brewer's yeast. Chromium is also found in grains and cereals, though much of it is lost when these foods are refined. Some brands of beer contain significant amounts of chromium." - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.) "Preliminary research in animals and humans suggested that chromium picolinate might increase fat loss and lean muscle tissue gain when a o 3 3 a used with a weight-training program.266,267,268 However, most studies have found little to no effect of chromium on body composition or strength.269,270,271 ¦272,273 One group of researchers has reported significant reductions in body fat in double-blind trials using 200 to 400 meg per day of chromium for six to twelve weeks in middle-aged adults,274,275 but the methods used in these studies have been criticized." - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"Effects of chromium picolinate on beginning weight training students. Int J Sports Nutr 1992; 2: 343-350 75. Clancy SP, Clarkson PM, DeCheke ME et al. Effects of chromium picolinate supplementation on body composition, strength, and urinary chromium loss in football players. Int J Sport Nutr 1994; 4: 142-153 76. Hallmark MA, Reynolds TH, DeSouza CA et al. Effects of chromium and resistive training on muscle strength and body composition. Med Sci Sports Exerc 1996; 28: 139-144 77. Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition." - Michael T. Murray, ND, Textbook of Natural Medicine 2nd Edition Volume 1 (Get the book.)

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