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"Often combined with glucosamine, it is sold in health-food stores. chondroitin stimulates the production of proteoglycans and hyaluronic acid and inhibits proteolytic enzymes, which destroy cartilage. chondroitin and glucosamine are often given in combination for osteoarthritis. Most of the earlier studies of glucosamine and chondroitin were performed by manufacturers and were not well controlled."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Oral chondroitin needs to be studied more thoroughly in larger number of patients, allowing more plausible evidence as to whether chondroitin is really a player or not. I also believe MSM (a natural anti-inflammatory) needs to be studied more thoroughly. But I have had several patients who experienced a significant response when they added it to their regime. Chondroitin Sulfate Several studies show improvement in patients with arthritis who are getting additional chondroitin."
- Ray D. Strand, What Your Doctor Doesn't Know About Nutritional Medicine May Be Killing You (Get the book.)

"Glucosamine is felt to be a precursor of proteoglycans, which are thought to be instrumental in helping cartilage retain water and in promoting formation of an elastic layer that may improve the functional characteristics of cartilage. chondroitin, a product derived from the cartilage of sharks and cows, is promoted for the prevention of arthritis and the treatment of joint pain. chondroitin stimulates the production of proteoglycans and hyaluronic acid and inhibits proteolytic enzymes, which destroy cartilage. Glucosamine and chondroitin are often combined and sold in health-food stores."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Chondroitin stimulates the production of proteoglycans and hyaluronic acid and inhibits proteolytic enzymes, which destroy cartilage. chondroitin and glucosamine are often given in combination for osteoarthritis. Most of the earlier studies of glucosamine and chondroitin were performed by manufacturers and were not well controlled."

- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Use caution in taking chondroitin sulfate if you are taking anticoagulants (blood-thinners) or daily aspirin, as it is chemically similar to the blood-thinner heparin. Pregnant women should not take these supplements, as there has not been sufficient study regarding their safety and potential side effects during pregnancy. Twinlab manufactures a number of good products containing chondroitin sulfate. Glucosamine chondroitin Sulfate from Only Natural, Inc., is a good combination source of glucosamine and chondroitin sulfate."
- Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)

"For a discussion of the reason for scepticism regarding the neutri-ceuticals, chondroitin and glucosamine, see the editorial by Felson and McAlindon, "Glucosamine and chondroitin for Osteoarthritis" (2000), and the two recent meta-analyses (Leeb and colleagues, "A Metaanalysis of chondroitin Sulfate in the Treatment of Osteoarthritis," 2000, and McAlindon and colleagues, "Glucosamine and chondroitin for Treatment of Osteoarthritis," 2000). From my perspective, these compounds are a waste of money. At least copper bracelets can be attractive."
- Nortin M. Hadler, The Last Well Person: How to Stay Well Despite the Health-Care System (Get the book.)

"No studies have been published on over-the-counter preparations of chondroitin sulfates and glucosamine preparations; however, a link has been established between chondroitin and IC.22 A GAG in the form of N-acetyl glucosamine or glucosamine sulfate can be used as part of a multifactorial approach to repair the bladder epithelium. Glucosamine Sulfate 750 mg twice daily N-Acetyl Glucosamine 500 mg twice daily Vitamin A."
- Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"Glucosamine is derived from shrimp, oyster, and crab shells, and chondroitin is derived from cartilage of cows, pigs, and sharks. There is no synthetically made glucosamine on the market. Glucosamine and chondroitin help regrow cartilage. However, if you have no cartilage left, these nutrients will not do any good to o artificial knees. They may help, though, with 2 your other joints. The best option is to prevent q the joint from getting to a stage of destruction (~) by using nutrients that help keep cartilage 70 tissue healthy. people with PKU."
- Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"In 2006 a large, well-controlled study assigned 1,583 patients with osteoarthritis of the knee to glucosamine, chondroitin, a glucosamine/chon-droitin combination, celecoxib, or placebo for six months of treatment. A positive treatment outcome was defined as a 20% change in knee-pain severity. Sixty percent of placebo patients responded to treatment vs. 67% of glucosamine/chondroitin patients, a difference that was not statistically significant. Celecoxib had a 70% response, which was statistically significantly better than that of placebo."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Chondroitin: This is usually found attached to proteins as part of a proteoglycan. chondroitin sulfate is a major structural component of cartilage and provides much of its resistance to compression. Along with glucosamine, chondroitin sulfate has become a widely used dietary supplement for treatment of osteoarthritis. Conjugated LinoleicAcid (CLA): Refers to group of modified forms of linoleic acid found in dairy products and meat."
- Jan Lovejoy, Get Balanced-the Natural Way to Better Health with Superfoods (Get the book.)

"Twinlab manufactures a number of good products containing chondroitin sulfate. Glucosamine chondroitin Sulfate from Only Natural, Inc., is a good combination source of glucosamine and chondroitin sulfate. Citrin Citrin is a trademarked name for a standardized herbal extract from the fruit of the Garcinia cambogia plant, also known as Indian berry. It inhibits the synthesis of fatty acids in the liver, promotes the burning of body fat as fuel, and suppresses the appetite."
- Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)

"Oil Those Joints Cetyl myristoleate or CMO is less known than glucosamine or chondroitin, but is also worth knowing about if you have arthritis pain. Clinical studies have shown that it increases joint mobility for up to 60 percent of the people who take it. CMO is an all-natural oil found in certain animals like cows, whales, mice, and beavers. Harry W. Diehl, Ph.D., a researcher at the National Institutes of Health, first discovered it in 1972. It has been used in a lot of arthritis research over the last 25 years."
- Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Glucosamine/chondroitin: 1,500 mg of glucosamine sulfate per day alone to start; if you don't discern any benefit within three months, try adding 1,200 mg of chondroitin daily ?MSM: Up to 6 grams daily ?Turmeric: 400-600 mg three times daily Don't forget to follow the diet and multivitamin recommendations from Chapter 2. All forms of arthritis respond well to natural treatments, including supplements. Most of these treatments are side-effect free, and they treat the problem at its root cause rather than simply addressing the symptoms."
- Hyla Cass, Supplement Your Prescription: What Your Doctor Doesn't Know About Nutrition (Get the book.)

"Dose: Start with 1,500 mg of glucosamine plus 1,200 mg of chondroitin, or start out with glucosamine only, adding chondroitin only if you don't feel benefits within about three months' time. Boswellia serrata Boswellia is a traditional Ayurvedic medicinal herb. It has been used to relieve arthritic symptoms for thousands of years. Modern research has pitted Boswellia against NSAIDs and found that it may be a more effective anti-inflammatory than the drugs."

- Hyla Cass, Supplement Your Prescription: What Your Doctor Doesn't Know About Nutrition (Get the book.)

"National Institutes of Health, 67 percent of 1,583 participants who took both glucosamine (1,500 mg) and chondroitin (1,200 mg) daily had reduced pain. (Keep in mind that 60 percent of the participants who took a placebo also reported a reduction in pain—a testament to the power of the placebo effect!) A separate analysis of participants who had moderate to severe pain found an enhanced effect of the glu-cosamine/chondroitin (pain reduction in 79.2 percent) combination over the placebo (pain reduction in 54.3 percent)."

- Hyla Cass, Supplement Your Prescription: What Your Doctor Doesn't Know About Nutrition (Get the book.)

"But many of these positive studies have involved actual IV injections of chondroitin, and some researchers are concerned that chondroitin is not effectively absorbed through the Gl tract. Some say that it is broken down, then absorbed, and reassembled within the joint cartilage. I feel further studies are needed to determine its overall importance in the treatment of osteoarthritis.8 Osteoporosis Osteoporosis is a nutritional deficiency at literally epidemic proportions in the U.S."
- Ray D. Strand, What Your Doctor Doesn't Know About Nutritional Medicine May Be Killing You (Get the book.)

"Chondroitin Often taken in combination with glucosamine, chondroitin is made of a complex group of sugar molecules categorized as glycosaminoglycans, which is the main ingredient of cartilage. chondroitin helps to reform damaged cartilage and to reduce inflammatory conditions. chondroitin sulfate has been known to lower cholesterol, reduce blood clots, inhibit plaque formation, and improve circulation. msm or methyisuifonyimethane This is a form of sulfur that is found naturally in fresh fruits, vegetables, and many other foods."
- Garcia Oz, Sharyn Kolberg, The Healthy High-tech Body (Get the book.)

"But many of these positive studies have involved actual IV injections of chondroitin, and some researchers are concerned that chondroitin is not effectively absorbed through the Gl tract. Some say that it is broken down, then absorbed, and reassembled within the joint cartilage. I feel further studies are needed to determine its overall importance in the treatment of osteoarthritis.8 Osteoporosis Osteoporosis is a nutritional deficiency at literally epidemic proportions in the U.S."
- Ray D. Strand, What Your Doctor Doesn't Know About Nutritional Medicine May Be Killing You (Get the book.)

"Our approach to people with chronic arthritic pain is to recommend natural anti-inflammatories such as fish oil, glucosamine, chondroitin, MSM, and willow bark. For now, we don't recommend the pharmaceutical anti-inflammatory drugs because they have too many downsides. In any case, two of the leading products—Vioxx and Bextra—have already been withdrawn from the market, and manufacturers of many other popular drugs in this class, both prescription and over-the-counter products, have been told by the FDA to include label warnings about potential health risks."
- Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)

"Chondroitin sulfate is another building block of connective tissue. It actually stimulates the cartilage cells (called chondrocytes), and therefore works beautifully when paired with glucosamine to speed the regeneration and recovery of bone tissues."
- Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"For a discussion of the reason for skepticism regarding the neutriceuticals chondroitin and glucosamine, I'd suggest the editorial by Felson and McAl-indon (2000), three meta-analyses (Leeb et al. 2000; McAlindon et al. 2000; Reichenbach et al. 2007), and the NiH-sponsored randomized controlled trial (D. O. Clegg et al. 2006). From my perspective, these compounds are a waste of money. At least copper bracelets can be attractive."
- Nortin M. Hadler MD, Worried Sick: A Prescription for Health in an Overtreated America (Get the book.)

"Glucosamine chondroitin Sulfate Vets worry less about whether there are seventy-five randomized, controlled, double-blind studies on skin rashes. If the vitamin supplement works—and does no harm—the vets use it. I was hearing about glucosamine from vets long before the medical establishment decided to get on board. It helps dogs—and people—with the pain, stiffness, and infirmity of arthritis."
- Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"In a separate 1-year, double-blind study of patients with osteoarthritis of the knee, supplementing with 800 mg per day of chondroitin sulfate significantly reduced pain, improved overall joint mobility, and appeared to slow the degenetation of joint cartilage.11 Improvement was evident after 3 months of treatment, and it became more marked after 12 months. Another study also showed that administering chondroitin sulfate may help prevent further joint damage in individuals with osteoarthritis."
- Jonathan V. Wright, M.D. and Alan R. Gaby, M.D., Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing (Get the book.)

"It is possible that chondroitin sulfate confers certain benefits that are not obtainable with glucosamine. We usually recommend glucosamine sulfate for our patients, without the addition of chondroitin sulfate. However, we have no objection if someone wants to use the more expensive combination treatment. Vitamin E and Selenium Vitamin E has a mild anti-inflammatory effect, similar to that of aspirin-like drugs. Although vitamin E is not nearly as strong as aspirin and related drugs, it also doesn't produce any of the side effects associated with these drugs."

- Jonathan V. Wright, M.D. and Alan R. Gaby, M.D., Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing (Get the book.)

"The best benefits result from combining chondroitin with another natural substance, glucosamine (see number 28). chondroitin is a substance found naturally in the body, where it helps maintain the integrity and elasticity of connective tissue, blood vessel walls, and other tissues. It does this by attracting water to cartilage, which acts as a shock absorber in the joints and promotes mobility. It also inhibits the activity of enzymes that destroy cartilage. Typical dosage: chondroitin is often taken along with glucosamine at a ratio of 5:4 (glucosamine:chondroitin)."
- Deborah R. Mitchell, The Home Healing Almanac: Solutions That Will Help You Make the Best Choices About Your Health and Safety (Get the book.)

"The proclivity to consume so-called neutriceuticals such as chondroitin and glucosamine is driven mostly by rumors promulgated by lay publications. Compounds of this nature can be sold without scientific or regulatory scrutiny. There will always be those with disposable cash who feel compelled to cast about for offbeat remedies. 4. Prior experiences and cultural presuppositions also play into whether one is likely to seek professional assistance in coping. This choice is subject to an influence far more powerful than the marketing by providers."
- Nortin M. Hadler MD, Worried Sick: A Prescription for Health in an Overtreated America (Get the book.)

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