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"Although other oils such as borage oil and black currant oil contain higher amounts of GLA, evening primrose oil is by far the most popular and familiar source of this fatty acid. Evening primrose oil also contains 11 percent oleic acid, 6 percent palmitic acid, and 2 percent stearic acid. Under ideal conditions, the body uses LA to produce GLA. In turn, GLA is used to produce beneficial hormone-like compounds called prostaglandins. Specifically, GLA is used to produce series one prostaglandins such as prostaglandin El (PGE1)." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"The omega-6 fatty acid GLA, which is low among many 4-A kids-particularly those with skin problems-is in primrose oil, borage oil, and black currant seed oil. The omega-3 EFAs are abundant in fish oil. EFAs are generally very well tolerated. The most common adverse reaction is possible bowel upset in some children, generally occurring only if they take an excessive dosage. As with most nutritional supplements, however, it is best to start at a lower dose and gradually increase to the desired dose." - Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.) "Another dietary measure that can be hugely helpful is taking supplements of essential fatty acids, such as fish oil, borage oil, evening primrose oil, or flaxseed oil. EFAs are potent antiinflammatories, and several studies indicate that they can help reduce the frequency, intensity, and duration of asthma episodes. Similarly, it's important to avoid the common foods that directly increase inflammation. The most important foods to avoid are those that are high in saturated fats-especially the trans-fatty acids found in many processed foods." - Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.) "The most powerful nutritional anti-inflammatories are: Anti-Inflammatory Nutrients • EFAs, including omega-3 (such as EPA and DHA) and GLA (such as borage oil, black currant seed oil, or evening primrose oil). • Quercitin, which is a natural antihistamine, and an antiinflammatory plant chemical. • Pycnogenol, which many people take in relatively high doses for allergy symptoms, due to its anti-inflammatory and antiallergic properties. • Curcumin, the active ingredient in the spice turmeric, which has powerful anti-inflammatory effects." - Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.)

"Evening primrose oil (like borage oil and black currant oil) is a natural source of a fatty acid called GLA—gamma-linolenic acid. Most of the health benefits of these oils can be attributed to the GLA content. However, the research on evening primrose and PMS has been mixed. Though some studies have shown it to be beneficial for PMS, many have not, though that may be because a great deal of the research used a preparation that contained only 40 mg of GLA. The average 1,000 mg dose of evening primrose oil contains about 100 mg of GLA." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Evening primrose oil, borage oil, and black currant oil contain large amounts of GLA and are used in PMS. To date studies using GLA oils did not significantly improve mood, but they have been shown to relieve breast pain. I recommend varying your omega-3 oils (flax oil, fish oil, cod liver oil, or krill oil) every two to three months with the GLA-rich omega-6 oils mentioned above (2,000 to 5,000 mg/day). 5. Adrenal supports will be discussed more fully in chapter 10, but it is important to understand that your adrenal glands are designed to produce your sex hormones as you age." - Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

"Examples of the sources of the fatty acids include borage oil and evening primrose oil. Conjugated linoleic acids (CLA) are a group of isomers of linoleic acid found in bovine lipids and in other ruminant animals that have been shown to have antiproliferative properties against several cancer cell lines [121]. These lipids also tend to reduce cell adhesion, decrease platelet aggregation, and alter several chemical mediators in the immune and inflammatory process [37, 38, 119-121]." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.) "Dietary fish oil and fish and borage oil suppress intrapulmonary proinflammatory eicosanoid biosynthesis and attenuate pulmonary neutrophil accumulation in endotoxic rats. Crit. Care. Med. 25, 1198-1206. 121. Sugano, M., Tsujita, A., Yamasaki, M., Noguchi, M., and Yamada, K. (1998). Conjugated linoleic acid modulates tissue levels of chemical mediators and immunoglobulins in rats. Lipids. 33, 521-527. 122. Jeppeson, P. B., and Mortensen, P. B. (1999). Colonic digestion and absorption of energy from carbohydrates and medium-chain triglycerides in small bowel failure. JPEN J. Parenter." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"Oral ingestion of borage oil has been shown to increase PG 1 levels in the skin and stop inflammation. borage oil is commonly found in health food stores. Trienelle Daily Renewal Cream (TDRC) This cream is reported to promptly restore a more normal healthy appearance to aging skin. Two of the key ingredients in this substance are natural tocotrienols extracted from Malaysian palm kernels and Japanese rice bran oil. Tocotrienols are an unusual form of Vitamin E that has profound skin protective properties." - James A. Howenstine, A Physician's Guide to Natural Health Products That Work (Get the book.)

"GLA is found in evening primrose oil, black currant seed oil, and borage oil. You can also get it as a supplement called GLA.) If you've got a picky toddler and you're panicked about how to get him to take evening primrose oil, try rubbing the oil on the affected areas at night (see box on page 123 for other oiling suggestions). Symptoms will improve gradually, and you'll very likely see a decreased need to use antihistamines. Bugs That Make You Well Now for the bugs." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"It may be better to get GLA directly from evening primrose oil, black currant oil, or borage oil supplements. ALA: Alpha-linolenic acid. This is an omega-3 fatty acid not commonly found in foods. Seven seed oils contain some ALA, with flaxseed oil being the richest natural source. Through several biochemical steps, the body converts ALA to EPA and then to prostaglandin 3. EPA and DHA: Eicosapentaenoic acid and doca-hexaenoic acid. These two omega-3 fatty acids are found in cold-water fish oils." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.) "That would mean instead of the 6 capules of evening primrose oil it would take to achieve the 3,000 mg of evening primrose oil that was used in the study, you could conceivably use at half as many capsules of borage oil. mmmmmmmmmmmmmimiimmmimmmmmmmmmmmm mi mmmmmmmmmmmmrmr* Evening Primrose Oil (Omega-6 Fatty Acids) 1,500 mg twice daily Vitamin A." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"He suggested borage oil. I tried it lone capsule after breakfast and one before bed), and within a few months the eczema on my hands disappeared completely. While I still have some outbreaks behind my ears, the condition is now only a minor annoyance. What a difference! Although some individuals have found gamma-linolenic sources such as borage oil, evening primrose oil, and black currant seed oil helpful, scientifically controlled studies of these supplements are disappointing.289 They do seem to be safe, but overall they don't reduce the rash or itching any more than placebo capsules do." - Joe Graedon, M.S. and Teresa Graedon, Ph.D., Best Choices From the People's Pharmacy (Get the book.)

"It's time they did. borage oil, made from borage plant seeds, contains an ample amount of gamma-linolenic acid (GLA), a fatty acid recently linked with a calming effect on research subjects who had reason to be riled. They took nine capsules a day for one month and were noticeably at ease in the face of a stressful event. \ • Multi-Symptom Stress Reliever Stress. Anxiety. Tossing and turning from insomnia. A treatment for all three of these symptoms, which often accompany one another, is Ignatia. This homeopathic remedy will lift your spirits and help you sleep." - Bottom Line Books, Uncommon Cures For Everyday Ailments (Get the book.)

"Otherwise, you will want to supplement with 1-2 tablespoons daily of otganic, cold-pressed, high-lignan flaxseed oil. • borage oil is more potent and less expensive than evening primrose or black current oil and is the best choice for gamma linolenic acid. • Fish oil provides DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid). • Recently a variation of a long-chain fatty acid cetyl ester called Omega-9 Plus?has been discovered." - Jon Barron, Lessons from The Miracle Doctors: A Step-by-Step Guide to Optimum Health and Relief from Catastrophic Illness (Get the book.)

"Whole and ground flaxseed and purified flaxseed oil are excellent sources of the two essential oils, linoleic acid and linolenic acid. borage oil and black current oil can be taken in capsule form as nutritional supplements. It should be stated, though, that all seed oils are not the same in their makeup of essential fatty acids, and substituting a seed oil does not necessarily give the same benefits as the fish oils and vice versa." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"DMSO can be obtained from DMSO Marketing 800-367 6935 GAMMA-LINOLENIC ACID is an essential fatty acid found in borage oil, evening primrose oil, or black current seed oil. These substances decrease the number of attacks of Raynaud's Syndrome, which may occur in scleroderma. In Raynaud's Syndrome, the small blood vessels of the hands, feet, ears, and nose go into spasm. The resulting pallor and white discoloration can be very painful. Borage oil and evening primrose oil can be found in health food stores. Is There Any Safe Way To Improve Muscle Endurance?" - James A. Howenstine, A Physician's Guide to Natural Health Products That Work (Get the book.)

"Are there any side effects or interactions? Borage seeds contain small amounts of liver toxins called pyrrolizidine alkaloids (PA). However, testing has not demonstrated the presence of the alkaloid in the seed oil.20 Most commercially available borage seed oil is, therefore, likely to be PA-free and presents no risk of PA toxicity. Minor side effects from borage oil use can include bloating, nausea, indigestion (page 260), and headache.21 What is it? Boric acid is a chemical substance with mild antiseptic, antifungal, and antiviral properties." - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"Dietary supplementation with ethyl ester concentrates of fish oil (n-3) and borage oil (n-6) polyunsaturated fatty acids induces epidermal generation of local putative anti-inflammatory metabolites. J Invest Dermatol; 1991;96(1):98-103. Mills DE, Mah M, Ward RP et al. Alteration of baroreflex control of forearm vascular resistance by dietary fatty acids. Am J Physiol; 1990;259(6 pt 2):R1164-R1171. Mills DE, Prkachin KM, Harvey KA et al. Dietary fatty acid supplementation alters stress reactivity and performance in man. J Hum Hypertens; 1989;3(2):111-116. Nissen HP, Biltz H & Muggli R." - Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.) "In patients with active synovitis, oral administration of borage oil in a single dose of 2.4 g GLA or a dose of 1.2 g twice daily for a period of 11 to 24 weeks resulted in suppression of T lymphocyte proliferation in vitro. Lymphocyte proliferation returns to pre-treatment levels by 3 months after discontinuation (Rossetti et al, 1997). Orally administered Borage seed oil can have an immunomodulatory function through effects on cytokine production." - Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.) "Nissen HP, Biltz H & Muggli R. borage oil. gamma-linolenic acid in the oil decreases skin roughness and TEWL and increases skin moisture in normal and irritated human skin. Cosmetics Toiletries Mag; 1995;110:71-73,76. Norred CL & Brinker F. Potential coagulation effects of preoperative complementary and alternative medicines. Alt Ther; 2001;7(6):58-67. Pittler M, Verster JC, Ernst E. Interventions for preventing or treating alcohol hangover: systematic review of randomized controlled trials. BMJ; 331:1515-1518. 2005. Rossetti RG, Seller CM, DeLuca P et al." - Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.) "Elevated levels of dihomogamma-linoleic acid (DGLA) resulting from a diet containing borage oil leads to an increase in series 1 prostaglandins. PGE-1 has been shown to cause signs of acute inflammation, yet also has a negative feedback role in the case of chronic inflammation. PGE-1 also inhibits the inflammatory process through the increase in cyclic AMP it produces, which in turn decreases leukocyte chemotaxis, margination, and adherence (Belch & Hill, 2000)." - Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.)

"Linoleic acid, a common fatty acid found in nuts and seeds and most vegetable oils (including borage oil), should theoretically convert to PGEi. Many things can interfere with this conversion, however, including disease; the aging process; saturated fat; hydrogenated oils; blood sugar problems; and inadequate vitamin C (page 604), magnesium (page 551), zinc (page 614), and B vitamins (page 603). Supplements that provide GLA circumvent these conversion problems, leading to more predictable formation of PGEi.2 Borage seed oil is the richest source of GLA, containing 20 to 26%." - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"Omega-6 oils are also sometimes used for health conditions such as arthritis, usually in the form of evening primrose oil, borage oil, black currant oil, or hemp oil. They should be thought of as medicinal supplements rather than as foods. Vitamin B12. Your body uses vitamin J312 to keep nerves and blood cells healthy. The amount you need is extremely small. The most convenient source is any typical multivitamin. You will also find it in many fortified breakfast cereals, fortified soy milk, and other supplemented products." - Neal D. Barnard and Bryanna Clark Grogan, Dr. Neal Barnard's Program for Reversing Diabetes: The Scientifically Proven System for Reversing Diabetes Without Drugs (Get the book.)

"Production: borage oil is the fatty oil of the seeds of Borago officinalis. Borage leaves are the dried leaves and inflorescence of Borago officinalis. The herb is harvested during the flowering period. Due to the plant's very high water content it should be artificially dried at 40°C. Not To Be Confused With: The herb can be confused with Echium vulgare." - Joerg Gruenwald, Ph.D., PDR for Herbal Medicines (Get the book.)

"GLA is found in evening primrose oil, borage oil, and black currant oil. borage oil is the most concentrated source of GLA, containing 24 percent GLA, the equivalent of six capsules of evening primrose oil. One 1.000 mg capsule of borage oil provides a daily dose of 240 mg GLA. Eicosapentaenoic acid (EPA). This oil found in fish and flaxseed oil produces prostaglandin-E3, which helps to alleviate breast tenderness. Flaxseed oil is fragile and should not be used in cooking. It can be used in salad dressings or over cooked foods. Vitamin E." - Dr. Gary Null, The Woman's Encyclopedia of Natural Healing (Get the book.)

"Sources of GLA include evening primrose oil, borage oil, and black-currant-seed oil. Other Recommendations: • Vitamin E, 400 to 800 IU per day. • High-potency multiple vitamin/mineral. • Treat "candida", in selected cases. • Assess digestion and absorption, and use appropriate digestive aids when indicated. Macular Degeneration age-related macular degeneration (AMD) is the leading cause of blindness in the United States and other developed countries." - Jonathan V. Wright, M.D. and Alan R. Gaby, M.D., Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing (Get the book.)

"Minor side effects from borage oil use can include bloating, nausea, indigestion (page 260), and headache.21 What is it? Boric acid is a chemical substance with mild antiseptic, antifungal, and antiviral properties. Boric acid is commonly used in the form of suppositories inserted in the vagina to treat yeast infection (page 454)." - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"No serious side effects occurred, although a few patients reported minor intestinal discomfort from borage oil.11 In another double-blind study, 16 patients with RA received 12 capsules of fish oil per day or a placebo for 12 weeks, then the other treatment for an additional 12 weeks. Fish oil was significantly more effective than the placebo in reducing joint swelling and morning stiffness.12 Supplementing with black-currant-seed oil has also been shown to relieve the symptoms of RA." It should be noted that different oils exert different effects in the body." - Jonathan V. Wright, M.D. and Alan R. Gaby, M.D., Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing (Get the book.) "In some cases, evening primrose oil or borage oil, which contain a fatty acid called gamma-linoleic acid (GLA), may be preferable to the other oils. Normally, the body converts linoleic acid (found in all of the oils listed above except cod-liver oil) into GLA, which is believed to play an important role in healing eczema. However, some individuals appear to have difficulty converting linoleic acid to GLA. In those cases a supplement that contains preformed GLA would be desirable." - Jonathan V. Wright, M.D. and Alan R. Gaby, M.D., Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing (Get the book.)

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