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Quotes about Vioxx from the world's top natural health / natural living authors

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"Merck Announces Voluntary Worldwide Withdrawal of VIOXX" www.vioxx.com/rofecoxib/vioxx/consumber/index.jsp Accessed August 2005. 4. "FDA Public Health Advisory: Safety of Vioxx" www. fda. go v/cder/drug/ infopage/vioxx/PH Avioxx. htm Accessed August 2005. 5. Bellis, Mary. "History of Antiseptics" inventors.about.com/library/inventors/blantisceptics.htm Accessed August 2005. 6. Starfield, Barbara. "Doctors are the Third Leading Cause of Death." Journal of American Medical Association, July 26, 2000; 284 (4): 483-5. Additional Reference Studies Ask K, Akesson A, Berglund M, Vahter M."
- Pat Sullivan, Wellness Piece by Piece: How a Successful Entrepreneur Discovered the Pieces to His Chronic Health Puzzle (Get the book.)

"For relief from the pain, many reach for remedies like the prescription drugs in the category known as COX-2 inhibitors (Celebrex and vioxx are famous examples), or pain relievers such as acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (Aleve). These drugs do offer immediate relief, but they're hardly without problems (witness the class-action suits over vioxx). O Keep in mind that none of them address 03 the underlying cause of the joint pa.n."
- Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Studies show that long-term users of both vioxx and Celebrex have more than twice the risk of heart attacks than those taking a placebo drug. As of this writing, Bextra (valdecoxib) is on the ropes, too, and question marks hang over the entire class of COX-2 inhibitors, part of the family of NSAIDs (nonsteroidal anti-inflammatory drugs). What are people in pain supposed to do? A GROWING PROBLEM The anti-inflammatory drugs were introduced into the marketplace for a good reason: increased inflammation."
- Carol Simontacchi, Natural Alternatives to vioxx, Celebrex and other Anti-Inflammatory Prescription Drugs (Get the book.)

"According to numerous reports, upwards of 140,000 people may have suffered a heart event as a consequence of taking either vioxx or one of the other COX-2 inhibitors. It should be noted that no one knows exactly why the new class of NSAIDs appears to increase the risk of heart disease. One theory that has been offered, however, is that these drugs suppress the body's production of prostacyclin, a prostaglandin that dilates the blood vessels and inhibits the formation of blood clots."

- Carol Simontacchi, Natural Alternatives to vioxx, Celebrex and other Anti-Inflammatory Prescription Drugs (Get the book.)

"In fact, the research project that recently illuminated the connection between the use of vioxx and an increased risk of heart disease was seeking to determine just how, and how much, cancer may be causally linked with inflammation. We hear more and more about rising health-care costs. How much does inflammation contribute to the health-care burden? In a few short years, Medicare will be unable to keep up with the growing costs. Insurance rates are rising faster than the Cost of Living Index, and there is no end in sight to skyrocketing prices."

- Carol Simontacchi, Natural Alternatives to vioxx, Celebrex and other Anti-Inflammatory Prescription Drugs (Get the book.)

"The COX-2 inhibitors were greeted with enthusiasm as first Celebrex (celecoxib), then vioxx (rofecox-ib), and then Bextra (valdecoxib) entered the market. Unlike the traditional NSAIDs, which came in over-the-counter strengths, these were all prescription drugs. Yet despite the fact that they required a prescription and cost far more than the traditional NSAIDs, the COX-2 inhibitors contributed to a dramatic increase in NSAID use."

- Carol Simontacchi, Natural Alternatives to vioxx, Celebrex and other Anti-Inflammatory Prescription Drugs (Get the book.)

"In short order Celebrex and vioxx each accounted for revenues that exceeded $3 billion per year. Merck and Pfizer convinced consumers and prescribers that their coxibs are worth the considerable extra expense compared to inexpensive over-the-counter aspirin and other nsaids. The advertising campaigns suggested that a sufferer could enjoy relief with diminished risk of gastrointestinal toxicity, as was predicted by the test-tube studies of the cox-2 inhibitors. They convinced patients and physicians alike, though they had never generated data that convinced the fda ?or me."
- Nortin M. Hadler MD, Worried Sick: A Prescription for Health in an Overtreated America (Get the book.)

"Another possible "obstacle" was described as a physician who says, "I am concerned with dose-related increases in hypertension with vioxx." The last four pages of the training document appear to provide the response Merck expected from any salesperson encountering these "obstacles." Each page contained a single word: "DODGE!" Yet the concern among physicians was just beginning."
- Melody Petersen, Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs (Get the book.)

"Painkillers and Heart Disease Revelations in 2004 and 2005 that best-selling painkillers such as vioxx, Celebrex, Aleve, and Bextra increase the risk of heart attacks made big headlines. The news stunned millions of patients relying on these medications. Ongoing news about possible adverse cardiovascular effects from medication makes us very concerned about the widespread use of painkillers altogether."
- Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)

"DES, Premarin, Thalidomide, and vioxx, to name a few, were all FDA-approved but are now known to be associated with increased risks of cancer, blood clots, birth defects, and heart disease. FDA approval does not mean that no possible harm can come to you from using a medication. ?There are no studies supporting the safety or efficacy of bioidentical hormones. This is not true. Bioidentical hormones have been used by physicians in this country and worldwide for over twenty years."
- Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

"That prescription drugs like vioxx have killed and injured hundreds of thousands of people does not seem to encourage these agencies to go out and warn the masses to think twice about taking prescription drugs. This would give the nearly one million people who die each year from the devastating side effects caused by prescription drugs a chance to save their lives. You always create harmful side effects when you treat the symptoms of disease without removing its underlying cause(s). How scientific or reasonable can it be to treat a disease for which the cause remains obscure?"
- Andreas Moritz, Cancer Is Not A Disease - It's A Survival Mechanism (Get the book.)

"Officers with power of investigation, 4 In 2004, the Merck arthritis drug, vioxx, was withdrawn from the market after it was admitted that it had created heart attacks and strokes in at least 60,000 patients. The withdrawal of vioxx cast a cloud of suspicion over all COX-2 inhibitors, including Celebrex and another Pfizer drug, Bextra. Bextra was shown to increase the incidence of heart attacks and strokes by 219% in a study carried out by the American Heart Association. The cardiologist who presented the study, Dr Garret Fitzgerald, called Bextra 'a time bomb waiting to go off."
- Martin J. Walker, HRT Licensed to Kill and Maim: The Unheard Voices of Women Damaged by Hormone Replacement Therapy (Get the book.)

"On September 30, 2004, Merck withdrew the painkiller vioxx from the market after it was linked to cardiovascular deaths, leading to congressional investigations. The FDA then came under fire from Congress for its handling of SSRI-induced suicidality, especially in children and youth.27 Then in the September 23, 2006, headline on the front page of The New York Times reported criticism of the agency in general: study condemns f.d.a.'s handling of drug safety: sweeping cflanges urged."
- Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"It's no wonder that serious safety concerns about drugs such as vioxx, Paxil, and Zyprexa have emerged very late in the day—years after they were in widespread use. Dr. Angell concluded that the FDA was becoming more dedicated to serving the drug companies than to serving the consumer of psychiatric drugs. Americans need to know that the FDA is not their friend. It's the friend of the pharmaceutical industry. _RhaptfiP 4 Young Girl Murderers in the Making THESE TWO STORIES are about young girls driven by Prozac into compulsive states of violence."

- Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"The herbs in Zyflamend work to reduce inflammation through mechanisms quite similar to those of NSAIDs like vioxx and Advil, however, they have a more "broad-spectrum" and balanced effect on the enzymes that create inflammation—offering similar benefits with fewer risks. INGREDIENTS Most of these herbs also work as antioxidants. Many have been used for thousands of years for a variety of medicinal purposes. Zyflamend's pharmacopoeia of herbs include the following: Holy basil {Ocimum sanctum) has demonstrated significant anti-inflammatory effects in animal studies."
- Freedom Press, Natural Cancer Cures: The Definitive Guide to Using Dietary Supplements to Fight and Prevent Cancer (Get the book.)

"Before the introduction of vioxx and Celebrex, sales of such antiinflammatory pain relievers had been in decline. It was not a market that excited analysts on Wall Street. Patients with arthritis could buy a variety of cheap and effective over-the-counter medicines like aspirin or ibuprofen and ease their pain for just pennies a day. But in 1998 news stories began to appear about the new "super-aspirins" that were coming soon. The media reports said the new drugs would offer great pain relief without the dangerous side effects of standard anti-inflammatory pain pills."
- Melody Petersen, Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs (Get the book.)

"Instead of ordering an x-ray or MRI and starting her on Celebrex or vioxx, we decided on a more practical approach: swimming as her only exercise until her knee started to improve; taking a low dose of an over-the-counter anti-inflammatory drug that would provide maximum or very near maximum pain relief and be much less likely to upset her stomach than a full dose; taking glucosamine and chondroitin sulfate daily, which would not start to help for a month or two but had a good chance of providing relief from the pain and making her knee somewhat more resilient to the trauma of exercise."
- John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"It took 18 months of vioxx treatment for the increased risk of heart attack to emerge. Most patients with heart disease were excluded from this study of Prexige, which is unlike the real world, where up to 40% of patients with arthritis also have heart disease or other significant risk factors. Lumiracoxib (Prexige) was also associated with a fourfold increase in elevated liver enzymes, indicating liver damage. In 2006 a review of COX-2 inhibitor safety from studies performed up to that time found a significant risk of cardiac events across the spectrum of COX-2 drugs."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Getting to the bottom of the Celebrex and vioxx stories would be difficult, but I had already done enough of this kind of research to know that it was usually worth poking around online. I started with Harvard Medical School's digital library, but couldn't find any new research or more complete data. Next I tried the government-sponsored "Pub-Med" website, a database of several thousand scientific journals; but a comprehensive search there didn't yield any new information either."
- John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"As I was about to find out, the articles about Celebrex and vioxx went a step further. A SEARCH FOR THE REAL DATA One might assume that anyone who was willing to go to the trouble of verifying conclusions presented in medical journals could do so. This is not the case at all. Drug companies often keep the results of their studies secret, even from their own researchers, on the grounds that such results are "proprietary information" of economic value."

- John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"How could the authors of the review article then dismiss the reported cardiovascular risk with vioxx on the grounds that there were "less than 70" cardiovascular events? Moreover, as I searched through the original VIGOR article, I couldn't find the number 70 anywhere, suggesting that the authors of the review had another source of information. Now I was determined to find out the real story. The articles about statins and strokes had shown me how effectively the drug companies can spin their "scientific evidence."

- John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"Drugs like vioxx and Celebrex were once thought to be miracles because they super-selectively inhibited COX-2, thought to be responsible for inflammation. Perhaps because of this super selectivity, researchers found these drugs caused distortions of the inflammatory process that might have been as bad as or worse than the targeted conditions. The body, after all, needs balanced inflammatory systems to function properly. Selective inhibition may be responsible for the cardiovascular concerns now associated with this class of drugs, and now many doctors are loathe to prescribe these medications."
- Freedom Press, Natural Cancer Cures: The Definitive Guide to Using Dietary Supplements to Fight and Prevent Cancer (Get the book.)

"The story of vioxx and Celebrex painkillers, unfolding as we write, is instructing us otherwise. That tens of millions of women were given estrogen replacements to alleviate symptoms of menopause and make them "feminine forever" is a good example from a few years earlier. A few years before that, 5-fluorouracil, a highly toxic drug, was widely used for the treatment of colon cancer—even though it was known at the time to be ineffective. What we are saying is that the medicalization of our lives—test this, monitor that, cut this, drug that—has a minimal impact on mortality."
- Gerald E. Markle and Frances B. McCrea, What If Medicine Disappeared? (Get the book.)

"This monetary set aside by Merck is a drop in the financial bucket compared to the revenue generated by vioxx during its five-year run, with annual sales estimated at $2.5 billion. In August 2004 the FDA conducted its own study that revealed the use of vioxx was associated with thousands of heart attacks or sudden cardiac deaths. What many Americans may wonder is why the drug was approved by the FDA in the first place. Testimony provided in February 2005 by Gurkirpal Singh M.D."
- Kelly Patricia O'Meara, Psyched Out: How Psychiatry Sells Mental Illness and Pushes Pills That Kill (Get the book.)

"Despite all this, White House chief of staff Andrew Card said in 2004 (in the wake of the vioxx scandal, no less) that the FDA was doing a "spectacular job."39 Given both a lack of resources and the fact that what resources it has are under political influence, the FDA's power to regulate the drug industry is surprisingly limited. For example, the agency reviews only a small percentage of the drug commercials that air on television. The FDA says, quite rightly, it doesn't have the resources to review the 54,000 drug promotions a year that come its way."
- Charles Barber, Comfortably Numb: How Psychiatry Is Medicating a Nation (Get the book.)

"Even after the woes that Big Pharma experienced between 2004 and 2007—the withdrawal of vioxx from the market, the loss of half of the injectable flu vaccines because of quality control problems, and a growing public awareness of profiteering and an all-too-cozy relationship with the Bush administration—no one should worry unduly about the industry's fortunes."

- Charles Barber, Comfortably Numb: How Psychiatry Is Medicating a Nation (Get the book.)

"Abraham C. vioxx makers 'perplexed' by Dosanjh's remarks. Today's Paper Health. http://www.theglobeandmail.com/servlet/ArticleNews/TPStory/LAC/20050226/ Vioxx26/TPHealth/ ALZHEIMER'S DISEASE AND SENILITY Prevalence As Dr Foster has described in his book, What Really Causes Alzheimer's Disease, this illness is increasing because life expectancies have risen significcantly during the past century."
- Dr. Abram Hoffer, MD, FRCP (C) and Dr. Harold D. Foster, PhD, Feel Better, Live Longer with Vitamin B-3 (Get the book.)

"In October 2004, vioxx, one of the main drugs used to treat arthritis, was voluntarily withdrawn by its manufacturers, Merck and Co. Some 70,000 deaths, largely from cardiovascular episodes, had been associated with this drug's use. Such toxic side effects had been known by the industry for several years. In February 2005, a panel of the U.S. Food and Drug Administration voted to allow the possible return of vioxx, provided it carried a striking black-box warning on its label about its cardiovascular risks. Patients who take it will be obliged to sign consent forms."

- Dr. Abram Hoffer, MD, FRCP (C) and Dr. Harold D. Foster, PhD, Feel Better, Live Longer with Vitamin B-3 (Get the book.)

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