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"But the facts are disturbing and question the growing practice of putting young people without CVD on statins for the purpose of prevention. Another point: statin drugs are expensive. They cost around $100 a month. If your risk is low, say 2 chances out of 100 that you will sustain a CVD event, and statin therapy reduces your risk to 1 chance out of 100 (the 50 percent risk reduction rate the drug companies talk about), should you spend $1,200 per year for the rest of your life to take a drug that will not prolong your life?"

- Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late(Get the book.)

"The study was motivated out of concern about CoQIO depletion among more than a hundred thousand patientstakingstatins in New Zealand. The researchers independently tested seven different blends of CoQIO without the knowledge of any of the manufacturers. Again, hydrosoluble CoQIO (Q-Gel) scored significantly higher than any other form of CoQIO supplement?in this case, 300 percent better than the average of the other products. Although an optimal CoQIO dosage is not yet known for every disease situation, researchers agree that bloodlevels of 2.5 ug/ml and preferably 3."

- Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late(Get the book.)

"Not only statins but beta blockers can inhibit CoQIO activity in the body. This may explain why some patients with heart failure worsen on beta blockers. CoQIO supplementation reduces beta blocker-induced fatigue. We have used CoQIO in conjunction with beta blockers, especially for the treatment of high blood pressure, arrhythmia, and angina. The combination works very well. Doctors should carefully monitor PT/INR in patients using Coumadin, especially if they feel CoQIO therapy is also indicated. Careful monitoring can allow the successful therapeutic use of both."

- Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late(Get the book.)

"It is extremely important that physicians be aware of the potential for statins to adversely affect coenzyme Qio levels. This effect certainly has major implications for patients with cardiac disease, and is especially true for patients with congestive heart failure or an overactive thyroid gland. These patients must be given supplemental doses of coenzyme Qi0 to offset the depleting effects of these cholesterol-lowering agents."
- Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.)

"In 1987, when the first of the statins, lovastatin, became available, that became our drug of choice.2 The most frequent objection I had heard to my ideas about nutrition—and it's the same objection I hear to this very day—was that patients would never comply with such major changes in their diet. So I was determined to give them all the support I possibly could. Years before, I'd heard the pioneering physician J. Engelbert Dunphy quoted as saying that cancer patients are not afraid of suffering or dying, but are afraid of being abandoned."
- Caldwell B. Esselstyn, Jr., M.D., Prevent and Reverse Heart Disease (Get the book.)

"The extract contains a number of cholesterol-lowering compounds known as statins. One of these is lovastatin, a substance also sold as a prescription drug under the brand name Mevacor. Lovastatin acts to lower cholesterol by inhibiting the action of an enzyme designated HMG-CoA reductase, which in turn limits the rate at which the body produces cholesterol. Studies have shown statins to lower cholesterol levels and reduce the risk of heart attack. Unlike prescription products, red yeast rice extract has shown no serious adverse side effects in clinical trials."
- Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)

"People who take statins have suffered ravaging health consequences, including permanent damage to their liver, muscles, and nervous system. statins frequently cause people to lose their memory or feel confused."
- Mike Adams, Natural Health Solutions (Get the book.)

"Today, the most widely prescribed therapy for high cholesterol is a class of drugs called statins. Although they are considered generally "safe" drugs, over time, statins can cause serious side effects, including liver damage. If you knew that you might be able to reduce your excess cholesterol by getting enough sunlight to convert it to vitamin D, wouldn't you rather hit the tanning salon before starting a lifetime of Lipitor? That's food for thought. CHAPTER IV HEY, BUD, CAN YOU DO ME A FAVA?"
- Dr. Sharon Moalem, Survival of the Sickest: A Medical Maverick Discovers Why We Need Disease (Get the book.)

"It's especially helpful for people who take statin drugs, because statins decrease levels of CQ10, which may be why statins can be associated with muscle cramps and pain— your arteries are literally being starved of energy and are crying for help. Niacin (vitamin B3) Sometimes A dose of 500 milligrams can lower LDL cholesterol and lower triglycerides, and help raise HDL. Take it with aspirin when going to bed to help decrease the risk of hot flashes, a common side effect. You can take a higher dose but need to talk to your doc because higher doses often need to be prescribed (Niaspan)."
- Mehmet C. Oz., M.D. and Michael F. Roizen, M.D., You: Staying Young: The Owner's Manual for Extending Your Warranty (Get the book.)

"Medication: statins, bile acid sequestrants, and intestinal cholesterol absorption inhibitors are the main medications prescribed. The specific medication used depends on the type of high cholesterol, which is measured as different lipoprotein types, that a patient is suffering from. If triglycerides are high, niacin and fish oil are used. Some of the side effects of cholesterol medication, especially from statins, are becoming well known. They include liver enzyme abnormalities due to liver damage and generalized muscle pain. These occur in some individuals but not all."
- Marshall Editions, 1000 Cures for 200 Ailments: Integrated Alternative and Conventional Treatments for the Most Common Illnesses (Get the book.)

"The newer cholesterol-lowering drugs (i.e., statins) not only lower cholesterol but also lower inflammatory mediators in the body. And since we know that chronic relentless inflammation causes arteries to be on fire, controlling cholesterol by either lowering oxidized LDL or raising HDL will be advantageous. I still recommend statins as part of my plaque reversal plan in patients with documented coronary artery disease. My grievance is when we aggressively treat high cholesterol numbers and not patients, and when we overprescribe these drugs for healthy people, especially women."
- Connie Bennett, C.H.H.C. with Stephen T. Sinatra, M.D., Sugar Shock!: How Sweets and Simple Carbs Can Derail Your Life-- and How YouCan Get Back on Track (Get the book.)

"Joint stiffness can also be a reaction to a number of drugs, including antibiotics such as minocycline, statins (used to lower cholesterol), and aromatase inhibitors (used to treat breast cancer). WARNING SIGN People with rheumatoid arthritis are at increased risk of suffering a heart attack or stroke. CREAKY KNEES Do your knees make you sound like the Tin Man from The Wizard o/Oz? If there's no pain involved, your creaky knees may be a sign of some benign temporary mechanical maladjustment."
- Joan Liebmann-Smith, Ph. D., and Jacqueline Nardi Egan, Body Signs: From Warning Signs to False Alarms...How to Be Your Own Diagnostic Detective (Get the book.)

"The group of drugs called the statins lower LDL and triglycerides, and some may raise HDL. Currently, these include lovastatin, pravastatin, simvastatin, fluvastatin, atorvastatin, and cerivastatin. They each come in several strengths. Bile acid sequestrants decrease LDL and increase HDL but do not lower triglycerides. These include cholestyramine, colestipol, and colesevelam. Nicotinic acid is used in three different forms: the immediate-release nicotinic acid (1.5-3 grams per day), the extended-release form (Niaspan, 1—2 grams), or the sustained-release form (nicotinic acid, 1-2 grams)."
- Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"In one clinical controlled trial, 59 patients who already had coronary heart disease and hypertriglyceridemia who were taking statins were able to significantly lower their levels of triglycerides and very low density lipoprotein (VLDL) when taking the fish oil and the statin.276 Another drug/fish oil study showed that 3.36 grams per day of fish oils were able to further decrease the triglycerides, total cholesterol, and apolipoprotein E than just the statin alone.277 The most compelling reason to give fish oils is if it in fact lowers heart disease."

- Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"The niacin and statins seem to act synergistically to improve lipid parameters at lower doses, in a shorter amount of time, and more effectively than when either is used alone.240-242 The major problem with the therapeutic dosage (1.5 to 3 grams per day) has to do with side effects. Flushing responses are common. Anecdotally, some clinicians decrease the effects of niacin's flushing by having the patient start with a low dose, like 500 mg per day, increasing the dose weekly to achieve the desired dose, and taking the dose before bed or coadministering with 81 mg baby aspirin."

- Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"Antioxidant properties of statins [Russian]. Kardiologia 45, 65-72. 112. Guzik, T. J., and Harrion, D. G. (2006). Vascular NADPH oxidases as drug targets for novel antioxidant strategies. 125. Drug Discovery Today 11, 524-533. 113. Richardson,M.A.,Sanders,T.,Palmer,J.L.,Greisinger,A.,and Singletary, S. E. (2000). Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology J. Clin. Oncol. 18,2505-2514. Burstein, H. J., Gelber, S., Guadagnoli, E., and Weeks, J. C. (1999). Use of alternative medicine by women with early-stage breast cancer. N. Engl."
- Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"Red yeast rice has shown benefit in clinical studies, but in an effort to protect the drug companies the FDA has restricted these products from having any active compounds. The statins are very popular prescriptions for diabetics, but as shown earlier, niacin can be more effective. However, some people will be able to achieve target cholesterol levels only with the aid of a statin. Statins are also gaining popularity as a prescription method to lower C-reactive protein (CRP), a marker of inflammation and a risk factor for heart disease."
- Michael T. Murray, Beat Diabetes Naturally: The Best Foods, Herbs, Supplements, and Lifestyle Strategies to Optimize Your Diabetes Care (Get the book.)

"A study published in the American Journal of Cardiology in 2003 showed that the amount of arterial disease (plaque) was not different in groups given high doses of statin drugs (lowering the cholesterol to one-half the normal value), compared with patients on low-dose statins (maintaining low-normal levels of cholesterol). Both groups had more plaque after one year. What's the Problem with Fat? So if cholesterol isn't the problem, how much and what kinds of fats can we safely eat? Some fats are better than others, and some fats should be avoided altogether."
- Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

"Emphasizing diet changes in general can boost the success rate of statins, while providing additional health benefits and a possible alternative for those for whom drugs are not a viable option," Dr. Jenkins adds. Most exciting is that these two together show more beneficial LDL cholesterol changes than doubling the dose of the statin medication. Talk with your doctor if you want to follow the plan, as your medication may need to be adjusted. for anyone concerned about reducing their risk of heart disease. Here's what you need to know. Power up with plant sterols."
- Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)

"Overall, this diet had a much more beneficial effect than either statins or weight-loss drugs, and without side effects. You'll lose weight eating this way, and you'll look and feel great. The Bottom Line Don't take diet pills, herbs, or supplements. Not for a few weeks, not for a few days, not ever. Not alone and not in combination with a diet program. In my opinion, diet drugs are a bad solution in the long and short term, even for people who have a lot of weight to lose (more than thirty pounds)."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"It is interesting to note that some statins and cholesterol-lowering medications have the curious side effect of disrupting short-term and long-term memory.5 These side effects are often dismissed because there is no known mechanism in conventional biology to explain them. However, they make perfect sense in NES theory because the information imprinted into fats in the bloodstream may act as a kind of body-wide memory storage and retrieval system."
- Peter h. Fraser and Harry Massey, Decoding the Human Body-Field: The New Science of Information as Medicine (Get the book.)

"In my opinion this push to give statins to people with normal cholesterol concentrations is a cause for concern. For one thing, we are introducing people who do not have a disease to medications with potentially dangerous side effects. Second, the body requires cholesterol for a number of vital processes, like the construction of cell membranes. Very low cholesterol concentrations have been linked to depression and suicide, possibly because of the impairment in the ability to maintain neurons in the brain."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Use of statins to treat high cholesterol has been associated with muscle pain and decreased exercise tolerance that has been correlated with a reduction in CoQIO.201-204 MHMBMMMMMMMMMMMMHHM^ CoQIO 50-150 mg per day Calcium. Calcium is most well known for its effects on bone health, but it can also be used to treat elevated cholesterol and hypertension. Calcium supplementation may produce modest reductions in blood pressure, usually only 1 or 2 points."
- Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"As for primary prevention, with its potentially huge market of well people, statins should be viewed as a false start and an object lesson. But there are billions of dollars of profit at stake for most of the major pharmaceutical firms. Marketing dollars flow into the coffers of advertising firms, of professional organizations, of "thought leaders" among cardiologists, endocrinologists, and prescribing physicians, and of political war chests and political action committees. Several voices have decried this marketing campaign."
- Nortin M. Hadler MD, Worried Sick: A Prescription for Health in an Overtreated America (Get the book.)

"In contrast, the University of British Columbia Therapeutics Initiative sent a letter to 12,000 British Columbia doctors in 2003 doctors stating that statins "have not been shown to provide an overall health benefit" when prescribed to people who have not already had a stroke or heart attack and do not have cardiovascular disease.12 More recently, Dr Graveline has reported that statins cause transient global amnesia.13 Mitigating Tobacco Use The use of tobacco is very stressful to the heart."
- Dr. Abram Hoffer, MD, FRCP (C) and Dr. Harold D. Foster, PhD, Feel Better, Live Longer with Vitamin B-3 (Get the book.)

"However, statins are effective in secondary prevention—that is, in preventing a recurrence of heart disease. In a book full of negative findings and criticism, it gives us great pleasure to review a carefully tested and efficacious treatment that undoubtedly saves lives. ACE INHIBITORS Angiotensin converting enzyme (ACE) inhibitors21 are a category of drug that relax blood vessels and thereby lower blood pressure; this same action allows the heart to work less hard and therefore ACE inhibitors are a common treatment for congestive heart failure."
- Gerald E. Markle and Frances B. McCrea, What If Medicine Disappeared? (Get the book.)

"Despite all their hype, statins have little effect on the prevention of second heart attacks; ACE inhibitors are no more effective than common diuretics. Finally, many commonly prescribed drugs are not only ineffective, but dangerous. The role of our pharmaceutical industry in overall health care is nothing short of a national scandal. We are not saying that contemporary medicine does no good. Nor are we advising readers to disengage from the system."

- Gerald E. Markle and Frances B. McCrea, What If Medicine Disappeared? (Get the book.)

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