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"Still another person responded to the above entry: "I've never eaten paxil but I got lots of twitches from Zoloft and from Wellbutrin. My doctor was a little surprised at my twitches, but not completely. I spoke to a couple of doctors about it including a Parkinson's disease researcher. I just had to get off those drugs because the twitches eventually caused me too much anxiety." Patients should not have to turn to the Internet in hopes of finding information that ought to be readily available from their doctors."
- Joseph Glenmullen, M.D., Prozac Backlash: Overcoming the Dangers of Prozac, Zoloft, paxil, and Other Antidepressants with Safe, Effective Alternatives (Get the book.)

"But this stuff started with the paxil so I think that's what's causing it." Reading this entry, I thought, Combinations of Buspar and a serotonin booster may be worrisome, since both have been implicated in involuntary movement disorders.58 Also worrisome are combinations of serotonin boosters and major tranquilizers. And increasingly, patients are prescribed two serotonergic drugs simultaneously in what psychopharmacologists call "drug cocktails," again, compounding the risks."

- Joseph Glenmullen, M.D., Prozac Backlash: Overcoming the Dangers of Prozac, Zoloft, paxil, and Other Antidepressants with Safe, Effective Alternatives (Get the book.)

"Prozac and paxil, for instance, primarily used in the treatment of depression, also act on these neurochemical systems. Some of these antidepressant drugs have been shown to induce weight loss and are prescribed specifically for this purpose. However, the effects of these drugs on weight are highly variable from drug to drug and from person to person: A drug that may induce weight loss in one person may cause weight gain in another. One of the antidepressants that has been most studied for weight loss is the selective serotonin reuptake inhibitor (SSRI) fluoxetine, or Prozac."
- J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Similar reports of agitation with Zoloft, paxil, and Luvox appeared after these drugs were introduced. In mild cases, patients may only experience foot-tapping and a vague sense of needing to keep busy. "I cleaned my house for days when I first went on Zoloft," said one patient. Said another, "I had a desk and six bookcases that I wanted to refinish for some time. Right after I went on Prozac I spent weeks compulsively sanding and finishing the furniture. At the time, I thought it was because my depression had lifted. Now I realize it was because I couldn't sit still."
- Joseph Glenmullen, M.D., Prozac Backlash: Overcoming the Dangers of Prozac, Zoloft, paxil, and Other Antidepressants with Safe, Effective Alternatives (Get the book.)

"In my report on Henry Rodgers's behalf, I wrote: Due to the involuntary intoxication caused by paxil, Mr. Rodgers was incapable of forming the intent necessary for the commission of the crimes associated with embezzlement. His medication-induced disability was a mental disease or defect that caused him to lack the substantial capacity to know or appreciate the nature and consequences of his actions from 2001 through May 2006. He was also unable to control his impulses and unable to conform his behavior to the law."
- Peter Breggin, Medication Madness: A Psychiatrist Exposes the Dangers of Mood-Altering Medications (Get the book.)

"Effexor and paxil have shown a reduction in sweats and flushes in studies at 37.5 to 75 mg and 10 to 20 mg daily, respectively. However, SSRIs and SNRIs have been occasionally shown to cause vasomotor symptoms in men and women. Bellergal Spacetabs, an ergot and belladonna combination, were used for many years for vasomotor symptoms but are no longer made by its pharmaceutical company. Some compounding pharmacies supply it. There are no studies on it, but empirical reports have shown mixed results. It is used one to two times daily."
- Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"With little data and with pressure from managed-care companies reluctant to approve psychotherapy, which they feel is more expensive, doctors have taken it upon themselves to dole out these drugs to patients whose heads are swimming with the latest paxil ad on TV. It is important to note, however, that much of the overprescribing is more well-intentioned, or at least naive or indifferent to the possible consequences, than conspiratorial."
- Charles Barber, Comfortably Numb: How Psychiatry Is Medicating a Nation (Get the book.)

"Some of these medications had been around since the 1950s and 1960s—mood stabilizers like lithium, antipsychotics such as Haldol and Thorazine—while others, at the time, were brand-new, with strange and exotic names like Prozac, paxil, and Zoloft. Each year over the course of the 1990s, new psychiatric medications were introduced and consumed en masse by my clients. Some of these new medications arrived with great fanfare and extremely high expectations."

- Charles Barber, Comfortably Numb: How Psychiatry Is Medicating a Nation (Get the book.)

"The people of the town may not know it, but Winterset is just one outpost, if a particularly prolific and lucrative one, of an economic and cultural phenomenon that has been building steadily since the 1988 arrival of Prozac, followed later by its cousins Zoloft and paxil. The one in six people of Winterset who take SSRIs and other antidepressants represent just one minuscule piece—one nail perhaps, or a little screw—of a towering, looming structure that has been building and growing and enlarging inexorably and relentlessly over the course of the 1990s."

- Charles Barber, Comfortably Numb: How Psychiatry Is Medicating a Nation (Get the book.)

"Tuesday, and swallowing their Prozac or paxil or Zoloft, were happily oblivious of this. Caught up in the national fervor of what the anthropologist T. M. Luhrmann has politely described as "psychopharmaco-logical overenthusiasm," the residents stood in line at the Montross Pharmacy and swallowed their pills at night.12 The size and reach of the psychiatric drug industry is staggering. It is far, far greater than most psychiatric practitioners realize and certainly greater than the drug companies would want you to know."

- Charles Barber, Comfortably Numb: How Psychiatry Is Medicating a Nation (Get the book.)

"Actually this is true for the majority of people, but in some less common cases it may take up to five weeks to work, about the same as a pharmaceutical antidepressant in the SSRI class, which includes Prozac, paxil, and Zoloft.) A review of eleven research papers on SAMe, published in Clinical Investigative Medicine in June 2005, concluded that "there appears to be a role for SAMe in the treatment of major depression in adults." Note the qualifier "major."
- Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"One study compared 5-HTP to fluvoxamine, an SSRI like Prozac, paxil, and Zoloft. In the study, subjects received either 5-HTP (100 mg) or fluvoxamine (50 mg) three times daily for six weeks. More patients felt better after using 5-HTP than fluvoxamine, and 5-HTP was quicker acting than the fluvoxamine. And in one other study, patients who were unresponsive to other antidepressant therapy showed significant improvement when using 5-HTP. Then there are headaches."

- Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"When Rupert explained the problem to his oncologist, he was put on paxil, an antidepressant. "Using paxil when you already have a libido problem is counterproductive," Dr. Borkin says. "Rupert didn't know that one of the side effects of paxil is loss of libido, so taking it only compounded his problem." Dr. Borkin, in consultation with Rupert's oncologist, took him off paxil, then began phase two of Rupert's treatment. This entailed dietary changes and gastrointestinal refortification, Neuro-Emotional Sensory Training (NEST), natural hormone replacement, exercise, and marriage counseling."
- Larry Trivieri, Jr., Alternative Medicine the Definitive Guide, Second Edition (Get the book.)

"In these instances, along with Redux, paxil, Propulsid, Zyprexa, and others, we owe the plaintiff's bar a debt of gratitude for forcing the fda toward regulatory remedies. Before you assume that I applaud the plaintiff's bar indiscriminately, I can assure you that I am well aware of and wont to condemn its excesses. The reference that discusses the negative psychological effects of labeling a well person as hypercholesterolemic is by Brett (1991)."
- Nortin M. Hadler MD, Worried Sick: A Prescription for Health in an Overtreated America (Get the book.)

"I'm curious about the muscle twitches I've had on paxil. Actually, I'd call them spasms. My stomach muscles will twitch so badly that it'll wake me up at night. Has anybody else experienced these spasms?" "Yup. Sounds familiar, and otherwise normal, for SSRIs." "When I was on Effexor, I got this weird side effect: While I was falling asleep or when my body was relaxed, like when I was lying down watching TV, I would get twitching in my legs and head/neck, like involuntary movements."
- Joseph Glenmullen, M.D., Prozac Backlash: Overcoming the Dangers of Prozac, Zoloft, paxil, and Other Antidepressants with Safe, Effective Alternatives (Get the book.)

"Paxil,2* with Augmentin29 $2.05 billion, and with Flovent30$l32 billion. Merck (headquarters in Whitehouse Station, New Jersey) won gold, silver and bronze in this Olympic race with Zocor,31 Vioxx32 and Cozaar33 ($6.6 billion, $2.5 billion and $1.9 billion).34 We will recount the exact story of Vioxx later. However, each of the giants in the pharmaceutical industry has top-selling products, and, in fact, one could go on and on, pages after pages, and quote those products, but the picture is always the same: the big pharmaceutical companies make their profit with just a few drugs."
- Kenneth W Thomas, Ron Gilbert, Gerd Schaller, Side Effects: The Hidden Agenda of the Pharmaceutical Drug Cartel (Get the book.)

"You may shift to another drug like paxil or Zoloft, and for a while things improve. Then the same problems come back. But you are committed to feeling better, so you keep searching for solutions. Perhaps you come across one of the popular diet books like Dr. Atkins' New Diet Revolution or Barry Sears's Mastering the Zone that talk about needing to stabilize your blood sugar by eating more protein or "balancing" each of your meals with a specific ratio of protein, fat and carbohydrate. These dietary plans identify many of the symptoms you feel."
- Kathleen DesMaisons, Potatoes Not Prozac: Solutions for Sugar Sensitivity (Get the book.)

"Zoloft? paxil? Luvox? Celexa? Effexor?and Serzone? Thanks to millions and millions of dollars in promotion, some misguided books that jumped on the bandwagon, and our own marvelous tendency to believe in magic bullets, we have become a "Prozac Nation." But not without cost. • SSRIs cause mania and delusions of grandeur in one out of every 25 children taking the drugs."
- Jon Barron, Lessons from The Miracle Doctors: A Step-by-Step Guide to Optimum Health and Relief from Catastrophic Illness (Get the book.)

"By the time the FDA had approved the drug for social anxiety, and SmithKline had unleashed its direct-to-consumer ad campaign, which could now link social anxiety to its cure, paxil, hundreds of stories about the illness had cropped up in U.S. publications and on broadcast programs. Social anxiety was everywhere, in the Washington Post, the New York Times, and Town and Country, on The Howard Stern Show and Good Morning America, and huge numbers of Americans were now worrying they might have it."
- Shannon Brownlee, Overtreated: Why Too Much Medicine Is Making Us Sicker and Poorer (Get the book.)

"Kratz, the Division Director of the Division of Neuropharmacological Drug Products, FDA, stated that the drug paxil was recommended to not be used to treat pediatric patients.148 145 SSRI: (selective serotonin reuptake inhibitor) a class of drugs, such as fluoxetine or sertraline, that inhibit the uptake of serotonin by neurons of the central nervous system and are primarily used in the treatment of depression and obsessive compulsive disorder."
- Kenneth W Thomas, Ron Gilbert, Gerd Schaller, Side Effects: The Hidden Agenda of the Pharmaceutical Drug Cartel (Get the book.)

"Mosholder discovered evidence that antidepressant drugs (serotonin reuptake inhibitors (SSRIs)), including paxil, Zoloft, and Effexor, could increase the risk of suicidal thoughts in children.135 FDA had assigned Mosholder the task of evaluating claims of an association between antidepressants and suicidal behavior in children in June of 20 03.136 Dr. Mosholder found evidence of increased risk of suicidal thoughts principally upon a review of twenty-two pediatric trials, involving 4,250 children."
- Jonathan W. Emord, The Rise of Tyranny (Get the book.)

"In December of 2003 the MHPRA declared antidepressants Zoloft, Lexapro, Celexa, Luvox, Serzone, Remeron, and paxil unsuitable for those under eighteen years of age.143 The Committee on Safety of Medicines, a subagency of the MHPRA, found "the risks of treating depressive illness in under 18s with certain SSRIs outweigh the benefits of treatment."144 Long before Mosholder issued his report, FDA management scheduled him to speak before a February 2, 2004 meeting of the FDA advisory committee considering safety risks associated with the prescription of SSRIs to children."

- Jonathan W. Emord, The Rise of Tyranny (Get the book.)

"GlaxoSmithKline played a similar card for its antidepressant drug paxil. In 1998, a generic drug maker filed an application with the FDA to market a generic version of paxil, but SmithKline Beecham (as the company was then called) alleged patent infringement, triggering the thirty-month extension. Since then, the company has filed suits regarding an additional four patents related to paxil, starting the thirty-month clock anew. Altogether, GlaxoSmithKline extended its exclusive rights by five years.26,27 Drug companies also use other strategies to extend lucrative patents."
- Richard A. Deyo M.D. M.P.H., Donald L. Patrick, Hope or Hype: The Obsession with Medical Advances and the High Cost of False Promises (Get the book.)

"The doctor told him to stop taking paxil and handed him several samples of Effexor, a similar antidepressant. The next day, Thursday, March 7, Justin took his first Effexor tablet. The following evening, while out with his girlfriend, he fell to the floor and suffered a seizure. He refused to go to the hospital, telling his girlfriend he just wanted to go home. On Sunday, Justin called his parents, telling his mother he still felt "really, really bad."
- Shannon Brownlee, Overtreated: Why Too Much Medicine Is Making Us Sicker and Poorer (Get the book.)

"First, the company tried encouraging doctors to prescribe the drug off label for post-traumatic stress disorder by funding and publishing several clinical trials testing paxil on people suffering from the condition. Unfortunately for SmithKline, however, the results of the trials failed to show the drug was effective, and the FDA refused to approve it for posttraumatic stress disorder. The company then turned to another condition, called social anxiety disorder, an extreme form of shyness that causes intense feelings of distress in social situations."

- Shannon Brownlee, Overtreated: Why Too Much Medicine Is Making Us Sicker and Poorer (Get the book.)

"And lastly one advertises like mad. 28 paxil treats social anxiety disorder, depression and panic disorder. 29 Augmentin is an antibiotic in the class of drugs called penicillin. 30 Flovent aids in preventing asthma symptoms before they start. 31 Zocor blocks the production of cholesterol (a type of fat) in the body. 32 Vioxx is used to relieve the pain and inflammation caused by osteoarthritis. It is also used to relieve minor pain, headache, and menstrual pain and discomfort. 33 Cozaar is used to treat high blood pressure."
- Kenneth W Thomas, Ron Gilbert, Gerd Schaller, Side Effects: The Hidden Agenda of the Pharmaceutical Drug Cartel (Get the book.)

"Vioxx was taken off the market because, even though it handled arthritic pain, it caused heart attacks and strokes.122 paxil was found out to create violence and suicide as well as seizures, but it is still on the market today. The usual way for doctors to handle these side effects is to prescribe a medication to handle them, and, of course, these medications come with yet other side effects. It's a dwindling spiral in the long run." "How do they justify giving patients so many drugs when the patient is just getting sicker? " Kevin L."

- Kenneth W Thomas, Ron Gilbert, Gerd Schaller, Side Effects: The Hidden Agenda of the Pharmaceutical Drug Cartel (Get the book.)

"Drugs like Prozac, paxil, Effexor and Zoloft belong to the second type. They turn off the reuptake pumps so secondhand serotonin stays between cells and continues to hit the serotonin receptors. In effect, your brain is getting more use out of the serotonin you have. These antidepressants tend to work better than the Pac-Man-blocking kind because they have fewer side effects. The good thing about drugs like Prozac is that they do increase your serotonin level and improve the problem moods and behaviors associated with low serotonin."
- Kathleen DesMaisons, Potatoes Not Prozac: Solutions for Sugar Sensitivity (Get the book.)

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