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"L-CARNITINE L-carnitine is an essential nutrient that is also synthesized in well-nourished bodies. l-carnitine is a derivative of the essential amino acid lysine. l-carnitine was named after meat (carnus) because it was first isolated from meat in 1905. Although it is not officially a vitamin, carnitine has been called vitamin By. L-carnitine is important in energy metabolism. It assists activated fatty acids into the mitochondria for energy production. It also assists in transporting metabolic debris out of the mitochondria." - Dr. Steve Blake, Vitamins and Minerals Demystified (Get the book.)

"Supplemental carnitine is available in different forms, including D-carnitine, l-carnitine, and DL-carnitine. DL-carnitine is not recommended, as it may cause toxicity. Acetyl-L-carnitine (ALC), a carnitine derivative produced naturally in the body, is involved in carbohydrate and protein metabolism and in the transport of fats into the mitochondria. It increases levels of carnitine in tissues and even surpasses the metabolic potency of carnitine." - Phyllis A. Balch, CNC, Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements (Get the book.)

"Other important substances include garlic (1,000 to 5,000 mg), onion (a raw onion a day helps keep strokes and heart attacks away), and l-carnitine (500 to 1,000 mg). l-carnitine increases energy by burning fat within the cell's mitochondria. This helps the body to recover quickly from fatigue." - Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)

"Studies suggest that people who take l-carnitine supplements soon after suffering a heart attack may be less likely to suffer a subsequent heart attack, die of heart disease, experience chest pain and abnormal heart rhythms or develop congestive heart failure. l-carnitine supplements create lower total cholesterol, triglycerides and an increase in HDL ("good") cholesterol. In addition, coronary artery disease sufferers using l-carnitine, along with standard medications, may be able to sustain physical activity for longer periods of time." - Jan Lovejoy, Get Balanced-the Natural Way to Better Health with Superfoods (Get the book.)

"Numerous other cardiovascular effects of l-carnitine are beyond the scope of this chapter, but improvement in exercise tolerance, functional improvement in angina, peripheral vascular disease, treatment of heart failure, and reduced death rates from heart attacks are all areas of clinical effectiveness of l-carnitine. L-Carm'tine 2-3 g per day Folic Acid, Vitamin B6, Vitamin B12." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"Other important substances include garlic (1,000 to 5,000 mg), onion (a raw onion a day helps keep strokes and heart attacks away), and l-carnitine (500 to 1,000 mg). l-carnitine increases energy by burning fat within the cell's mitochondria. This helps the body to recover quickly from fatigue." - Gary Null and Amy McDonald, The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing (Get the book.)

"AT-acetyl-carnitine is preferable to the more common l-carnitine, because it tends to be more neuroactive. The supplement has been shown to improve cognitive function, and some researchers believe that it heightens the communication ability between the two hemispheres of the brain. It is a potent brain antioxidant, and is frequently used by people who suffer from age-associated memory impairment, or from Alzheimer's. Indicators that it may be needed include the following: • Elevated blood triglycerides. • Low levels of carnitine in the blood." - Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.)

"L-carnitine: 500-2,000 milligrams (mg) of l-carnitine daily in divided doses. A special esterified form called acetyl-L-carnitine (at the same dosage) is preferable when the brain and nervous system are involved. Carnitine is an amino acid produced in the body from an essential amino acid called lysine. It's highly concentrated in muscle, heart, liver, and kidneys, and is important for regulating heart function. Carnitine also transports fats into cells to be burned for energy in the mitochondria." - Hyla Cass, Supplement Your Prescription: What Your Doctor Doesn't Know About Nutrition (Get the book.) "Needed supplements: ?L-carnitine: 500-2,000 milligrams (mg) of l-carnitine daily in divided doses. A special esterified form called acetyl-L-carnitine (at the same dosage) is preferable when the brain and nervous system are involved. Carnitine is an amino acid produced in the body from an essential amino acid called lysine. It's highly concentrated in muscle, heart, liver, and kidneys, and is important for regulating heart function. Carnitine also transports fats into cells to be burned for energy in the mitochondria." - Hyla Cass, Supplement Your Prescription: What Your Doctor Doesn't Know About Nutrition (Get the book.)

"Typical daily dose: Either 125-250 mg of acetyl-L-carnitine or 250-500 mg of l-carnitine, twice a day MOVING ON After you've spent at least six weeks in Phase 2-assuming you are getting close to your goal weight and your cholesterol and other markers indicate that you're continuing to make progress-it's time to think about moving to Phase 3. In the next two chapters, we'll look at how to extend not only your life span but, more important, your "health span." 1 DR." - Dr. Steven R. Gundry, Dr. Gundry's Diet Evolution: Turn Off the Genes That Are Killing You - And Your Waistline - And Drop the Weight for Good (Get the book.) "Typical daily dose: For anyone on a statin drug, take at least 50 mg; to reduce Lp(a) levels, at least 150-250 mg is useful Acetyl-L-carnitine or l-carnitine These act at the level of the muscle fiber to transport energy into and around the individual muscle cells, particularly the energy-producing mitochondria. Studies of my patients with congestive heart failure and/or cardiomyopathy have often shown dramatic improvement in heart muscle and other muscle function with daily supplementation.6 Two of my patients improved to such an extent that both were removed from the heart transplant list." - Dr. Steven R. Gundry, Dr. Gundry's Diet Evolution: Turn Off the Genes That Are Killing You - And Your Waistline - And Drop the Weight for Good (Get the book.)

"In addition to CoQIO and magnesium, research shows that the amino acid l-carnitine also prevents future angina attacks. For example, one research study demonstrated that l-carnitine supplements completely eliminated angina attacks in 22 percent of patients suffering from the disease. l-carnitine and 1-arginine, an amino acid that may also treat and prevent angina, are both widely available in supplement form. Angina attacks are painful and often terrifying, especially if a sufferer mistakes the attack for a heart attack." - Mike Adams, Natural Health Solutions (Get the book.)

"Needed supplements: • L-carnitine: 500-2,000 milligrams (mg) of l-carnitine daily in divided doses. A special esterified form called acetyl-L-carnitine (at the same dosage) is preferable when the brain and nervous system are involved. Carnitine is an amino acid produced in the body from an essential amino acid called lysine. It's highly concentrated in muscle, heart, liver, and kidneys, and is important for regulating heart function. Carnitine also transports fats into cells to be burned for energy in the mitochondria." - Hyla Cass, M.D., Supplement Your Prescription: What Your Doctor Doesn't Know About Nutrition (Get the book.)

"Numerous other cardiovascular effects of l-carnitine are beyond the scope of this chapter, but improvement in exercise tolerance, functional improvement in angina, peripheral vascular disease, treatment of heart failure, and reduced death rates from heart attacks are all areas of clinical effectiveness of l-carnitine. L-Carm'tine 2-3 g per day Folic Acid, Vitamin B6, Vitamin B12." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"L-carnitine are often taken as well. When patients have followed this program along with weight reduction and exercise, I have consistently been able to reduce, or eliminate, their reliance on antihypertensive medications. For a more complete discussion on natural high blood pressure lowering, the reader is referred to my book Lower Your Blood Pressure in Eight Weeks (Ballantine Publishing, 2003). Coenzyme Q10 is the bellwether of any natural hypertensive lowering regime." - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.)

"Supplements A number of supplements can improve sperm quality and quantity, including vitamins C, B12, and E; L-arginine; L-carnitine; selenium; zinc; and folic acid.58 Vitamins C and E. Vitamin C and other antioxidants can decrease sperm DNA damage that can interfere with fertility.59 Vitamin C deficiency has been linked with significant decreases in sperm count, motility, and vitality and with an increase in morphologically abnormal sperm.60 Vitamin E and selenium have been shown to reduce lipid peroxidation and, therefore, improve sperm quality." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"It helps form l-carnitine. This amino acid helps metabolize fatty acids. Many autistic kids have trouble metabolizing fatty acids, and this can cause neurological and GI symptoms. • // helps balance hormone /^^-particularly those of oxytocin, vasopressin, and cholecystokinin, which are often unbalanced in autistic kids. Oxytocin, in particular, is important for emotional bonding. Women giving birth typically experience a surge of oxytocin. • It can help modulate immunity, which is often impaired in children with 4-A disorders." - Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.)

"He also added 1,000 mg daily of l-carnitine to reduce blood glucose levels further and for heart health. He admitted that following the antiglycation eating program was "a bit difficult, especially since I really love fried foods," but that his wife was "holding me to it. Poached fish, soups, and oatmeal are now a big part of my diet." Nine months after he was first diagnosed with type 2 diabetes, Frank weighs in at 205 pounds, his Hb A is 6.2 percent, and his fasting glucose level averages 115 mg/dL." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.) "Controlled study on l-carnitine therapeutic efficacy in post-infarction. Drugs Exp Clin Res 1992; 18(8):355-65. De Gaetano A et al. Carnitine increases glucose disposal in humans. J Am Coll Nutr 1999; 18:289-95. Dewailly E. n-3 fatty acids and cardiovascular disease risk factors among the Inuit of Nunavik. Am J Clin Nutr 2001 Oct; 74(4):464-73. Dewailly E. Fish consumption and blood lipids in three ethnic groups of Quebec (Canada). Lipids 2003 Apr; 38(4):359-65. Dincer Y et al." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.) "Mingrone G et al. l-carnitine improves glucose disposal in type 2 diabetic patients./Aw Coll Nutr 1999; 77-82. Mita T et al. Eicosapentaenoic acid reduces the progression of carotid intima-media thickness in patients with type 2 diabetes. Atherosclerosis 2007 Mar; 191 (1): 162-67. Miura Y et al. Tea catechins prevent the development of atherosclerosis in apoprotein E-deficient mice. J Nutr 2001; 131(l):27-32. Montori V et al. Fish oil supplementation in type 2 diabetes: A quantitative systematic review. Diabetes Care 2000; 23:1407-15. Mori TA. Omega-3 fatty acids and hypertension in humans." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.) "Three-year survival of patients with heart failure caused by dilated cardiomyopathy and l-carnitine administration. Am Heart J 2000; 139(2 Pt 3):S120-23. Rodriguez-Moran M and Guerrero-Romero F. Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: A randomized double-blind controlled trial. Diabetes Care 2003 Apr; 26(4): 1147-52. Rosenblat M et al. Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages. Atherosclerosis 2006 Aug; 187(2):363-71. Sanchez-Ramirez GM et al." - Steven V. Joyal, What Your Doctor May Not Tell You About Diabetes: An Innovative Program to Prevent, Treat, and Beat This Controllable Disease (Get the book.)

"If you think of your body as an automobile, then l-carnitine and CoQ 10 can be thought of as agents (like spark plugs) that help turn the gas in the tank into energy to make the car go. D-ribose, the third component of this quartet (which Sinatra calls the Awesome Foursome), For a more detailed discussion of the biochemistry of these four nutrients, and for recommended doses for a variety of health conditions, check out Stephen Sinatra's excellent book, The Sinatra Solution: Metabolic Cardiology. At the very least, give it to your doctor. can be thought of as the actual gas." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.) "In one study, the walking capacity of patients with intermittent claudication—a painful cramping sensation in the muscles of the legs due to decreased oxygen supply—improved significantly when they were given oral l-carnitine. In another study, patients with peripheral arterial disease of the legs were able to increase their walking distance by ninety-eight meters when supplemented with carnitine, almost twice what those given a placebo were able to do. Congestive heart failure patients have experienced an increase in exercise endurance on only 900 mg of carnitine per day." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.) "Many people feel a lot better on an "energy" cocktail of l-carnitine and CoQIO. Rounding out the quartet with D-ribose and magnesium, as suggested by Sinatra, is a great idea, especially for heart patients. (Magnesium helps because it is critical for the making of ATP, has an important effect on cellular metabolism, has been found helpful in a wide range of cardiac Ribose and Fibromyalgia Just as we went to press, my friend and go-to guy for all things related to Fibromyalgia and Chronic Fatigue Syndrome, Jacob Teitelbaum, M.D." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Thus, increased levels of l-carnitine accelerate energy metabolism, while low levels impair it. Another important function of the carnitine shuttle (see Figure 5.3) is the removal of excess acyl units from inside the mitochondria. This capability of carnitine is important because excessive acyl units that accumulate inside the mitochondria disturb the metabolic burning of fats. Other crucial functions of Cristae Matrix Figure 5.2. Mitochondria Structural Features MUSCULAR FIBER vJiTMilannfiYTTT'T''r Figure 5.3." - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.)

"As you may recall, one of the early symptoms of vitamin C deficiency is fatigue, which may be related to the decreased synthesis of l-carnitine. Vitamin C is needed to make the neurotransmitter norepinephrine. Norepinephrine is created in response to physical stress. This is one reason why more vitamin C is needed for stress. Vitamin C also acts as a cofactor for the enzyme that catalyzes the conversion of the neurotransmitter dopamine to norepinephrine. More vitamin C is needed in times of stress. The adrenal glands contain more vitamin C than any other organ in the body." - Dr. Steve Blake, Vitamins and Minerals Demystified (Get the book.)

"Cellular energy turnover, assisted by l-carnitine and coenzyme Q10, is vital to cellular health. Remember, however, that in addition to energy turnover the total concentration of energy substrates in the cell is equally vital. That is where D-ribose comes into play. Balancing the Energy Supply—Squeezing Energy Out of the Pool The continual supply of energy requires rapid turnover and resynthesis of ATP Under normal, healthy circumstances, the use and recycling of cellular energy progresses unimpeded millions of times per second in every cell in the body." - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.) "Another important function of the l-carnitine shuttle is the removal of acyl units from inside the mitochondria. This function is important when too many acyl units accumulate inside the mitochondria and disturb the metabolic burning of fats. Other crucial functions of carnitine include the metabolism of branched-chain amino acids, ammonia detoxification, and lactic acid clearance. Remember that lactic acid accumulation has been shown to have deleterious effects on vital tissues, such as the heart and brain." - Stephen T. Sinatra, M.D., The Sinatra Solution Metabolic Cardiology (Get the book.)

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