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NaturalPedia > Human Genome
Quotes about Human Genome from the world's top natural health / natural living authors
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"Francis Collins, Director, National human genome Research Institute
In the year 2000 scientists completed the first survey of the human genome. Then-President Bill Clinton announced the accomplishment at a White House press conference, congratulating scientists working in the public and private sectors on what was a "landmark achievement, which promises to lead to a new era of molecular medicine, an era that will bring new ways to prevent, diagnose, treat, and cure disease."1
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A new era had begun for the Alzheimer's field." - Peter J. Whitehouse and Daniel George, The Myth of Alzheimer's: What You Aren't Being Told About Today's Most Dreaded Diagnosis (Get the book.)
| "Two eminent professors express it this way: "Remembering that the information in the human genome has to cover the development of all other bodily structures as well as the brain, this is not a fraction of the information required to structure in detail any significant brain modules, let alone for the structuring of the brain as a whole."20
The human genome Project initially was focused on cataloging all the genes of the human body." - Dawson Church, The Genie in Your Genes: Epigenetic Medicine and the New Biology of Intention (Get the book.)
| "Although mapping the human genome was certainly an awe-inspiring achievement for molecular biology and the discovery of the association between ApoE and AD a positive advancement in our understanding of the genetics of brain aging, none of our findings have resulted in clear advancements in the way we approach AD. Individual risk assessments are widely seen as being too vague to have any use in clinical care." - Peter J. Whitehouse and Daniel George, The Myth of Alzheimer's: What You Aren't Being Told About Today's Most Dreaded Diagnosis (Get the book.)
| "Eric Landers, who was at the forefront of the human genome Project, has called the genome a parts list. Having a parts list alone does not tell you what the pieces are for and how to combine them into something useful.18 You need an information template for that.
DNA is an alphabet of only four letters, the chemicals (called bases) adenine, thymine, cystosine, and guanine, yet combinations of those four bases, we are told, determine many, if not most, of our core characteristics, from the color of our eyes to our propensity for developing certain diseases." - Peter h. Fraser and Harry Massey, Decoding the Human Body-Field: The New Science of Information as Medicine (Get the book.)
"On their human genome Project website, they report that environmental factors may be the single most important trigger in whether a genetic mutation is expressed or not: "Scientists estimate that each of us carries between 5 and 50 [gene] mutations that carry some risk for disease or disability. Some of us may not experience negative consequences from the mutations we carry, either because we do not live long enough for it to happen or because we may not be exposed to the relevant environmental triggers."
- Peter h. Fraser and Harry Massey, Decoding the Human Body-Field: The New Science of Information as Medicine (Get the book.)
| "Completion of the human genome sequence and the advent of DNA microarrays using cDNAs enhanced the detection and identification of hundreds of differentially expressed genes in response to antioxidants including flavonoids, selenium, zinc, and several vitamins [67]." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
"This systems biology approach has been facilitated by the availability of the public information generated by the human genome Project and the HAPMAP [294].
We should also be cautious concerning the interpretation of studies of association between allelic variants and common phenotypes. We should direct attention to the population admixture, which can cause an artificial association if a study includes genetically distinct subpopulations, one of which coincidentally displays a higher frequency of disease and allelic variants."
- Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
| "Our Genetic Blueprint and the Fates
Even before the mapping of the human genome, the medical community had begun linking genetics to an increased risk for a wide variety of illnesses, like asthma, diabetes, heart disease, and depression. Unfortunately, many people saw this as an invitation to blame everything on our genes and, therefore, simultaneously believe they had no control over their health. Yet, for all of these diseases, our behaviors, thoughts, and emotions still play a large part in their severity, our symptoms, and our ability to recover or live with them." - Rick Foster, Greg Hicks, M.D., Jen Seda, Choosing Brilliant Health: 9 Choices That Redefine What It Takes to Create Lifelong Vitality and Well-Being (Get the book.)
| "When genetic scientists proposed that genes control the body and behavior, they developed the human genome project to prove exactly that hypothesis. Paid for by the pharmaceutical companies, these scientists had just one major objective; they had to fulfill the expectations of the big pharma conglomerate to patent genes for new, expensive "breakthrough" treatments that generate vast amounts of wealth. Nowhere do they mention the proven biomedical fact that genes do not control anything. The genes' only function and purpose are to reproduce cells." - Andreas Moritz, Cancer Is Not A Disease - It's A Survival Mechanism (Get the book.)
| "Conclusion making Sense of mind-body medicine
-wj- Jre live in a world where scientists have mapped the human genome, where the pharmaceutical industry is a multibillion-dollar business, and where people look to the brain sciences to illuminate everything from schizophrenia to shyness. Reductionist medicine, it would seem, has triumphed. Nevertheless, this book has been all about demonstrating that there is more to say—much more. In March 2007, I conducted an internet search on Amazon.com using several keywords." - Anne Harrington, The Cure Within: A History of Mind-Body Medicine (Get the book.)
| "Online genetic databases informing human genome epidemiology. BMC Med. Res. Methodol. 7,31.
CHAPTER LV
The Role of Diet in the Prevention and Treatment of Cardiovascular Disease
MICHAEL ROUSSELL, JESSICA GR1EGER, AND PENNY M. KRJS-ETHERTON
Pennsylvania State University, University Park, Pennsylvania
Contents
I. Introduction 515
II. Dietary Fat 516
III. Dietary Carbohydrate 526
IV. Dietary Protein 529
V. Alcohol 531
VI. Dietary Cholesterol 532
VII. Plant Sterols/Stanols 533
VIII. Supplements 534
IX. Food-Based Guidance 535
X. Summary/Conclusion 539 References 539
I." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
| "The completion of the human genome Project in 2001, also, by association, has served to bolster psychiatry's newfound scientific image. That a rough draft of the human genetic makeup has been developed contributes to a popular belief that psychiatric disorders proceed in neat Mendelian inheritable patterns. But if anything has been gleaned for the last two decades of work in the genetics of psychiatric disorders, it is that it is a terribly complex business. No single gene for psychiatric disorders have been found and likely will never be found." - Charles Barber, Comfortably Numb: How Psychiatry Is Medicating a Nation (Get the book.)
| "Since the human genome has been deciphered, we now recognize that there is vast biochemical variability within the population.
We all have unique nutritional and biochemical needs.
Using a single baseline for determining the dietary reference intakes for different people in the population does not fit with our understanding of this biochemical diversity. Different people have different needs. Some need more of particular types of vitamins and minerals than others." - Mark Hyman MD, The UltraMind Solution: Fix Your Broken Brain by Healing Your Body First (Get the book.)
| "For cardiologists, the human genome Project, which has mapped the location and role of various genes, has opened new doors to the diagnosis and treatment of CVD. When people say "it's a family thing" referring to somebody's illness, we are now starting to have specifics about what that means. And along with the specifics come better solutions.
Take the case of Sid as an example. He had successful coronary artery bypass surgery in the late 1990s and had been enjoying a good quality of life ever since. But he continued to have high blood pressure." - Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)
| "There's great variability among the human genome, which makes some of us more susceptible to various environmental and toxic stresses than others. You may be more prone to heart disease, and another person may be more prone to a certain type of cancer. But it doesn't mean that without those environmental stresses they would've ever developed heart disease or cancer. It's not genetic in the sense that you can't do anything about it. It just means that under a certain set of environmental challenges, this body is more prone to develop certain weaknesses." - Deirdre Imus, Growing Up Green: Baby and Child Care: Volume 2 in the Bestselling Green This! Series (Green This!) (Get the book.)
"Another reason to do the study now is that "we've decoded the human genome. We can now measure the DNA of the mother and the father and the baby. We can identify the different genes that are present in them, and we can look for the interplay between the environmental exposures and the genes. Everybody's different. Different people react differently to different chemicals. And by knowing both the chemicals and the genes, we can map all that out."
You might be thinking: Fine. This is all very interesting, but what does the National Children's Study have to do with me?"
- Deirdre Imus, Growing Up Green: Baby and Child Care: Volume 2 in the Bestselling Green This! Series (Green This!) (Get the book.)
| "For the past six years, I have been funded by the National human genome Research Institute through its Ethical, Legal and Social Implications program (ELSI) and the National Institute on Aging study providing ApoE information to persons at risk for dementia. This work has been conducted with Melissa Butson in Cleveland, and with colleagues at Boston University (where my friend Bob Green is the overall study principal investigator), the University of Michigan, Cornell University, and Howard University." - Peter J. Whitehouse and Daniel George, The Myth of Alzheimer's: What You Aren't Being Told About Today's Most Dreaded Diagnosis (Get the book.)
| "An evaluation of new criteria for CpG islands in the human genome as gene markers. Bioinformatics. 20, 1170-1177.
83. Bestor, T. H. (2000). The DNA methyltransferases of mammals. Hum. Mol. Genet. 9, 2395-2402.
84. Lei, FL, Oh, S. P., Okano, M., Juttermann, R., Goss, K. A., Jaenisch, R., and Li, E. (1996). De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development 122, 3195-3205.
85. Okano, M., Xie, S., and Li, E. (1998). Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat. Genet. 19, 219-220.
86. Oligny, L." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)
| "And when asked about the completion of the Genome Project, he replies:
What does it mean when we say that the human genome is completed? It is not completed. Three billion nucleotides, which is three times the size of the human genome, have been sequenced, but we do not have complete genes and the sequences have not been identified . . . the next step will take a long time and cannot be done by computers.
(The Lancet, Oncology, 1 September 2000, p." - Michael Gearin-Tosh, Living Proof: A Medical Mutiny (Get the book.)
"There is the human genome Project. We read that its aim is to analyse our genetic structure, and to catalogue and map all the individual genes in the body. The completion of the Genome is a new era of hope according to the press, and not just the popular press:
The monumental advances in molecular oncology and in understanding the human genome are leading to an explosion of new and novel therapeutic agents ...
(Clinical Cancer Research, February 2001, p."
- Michael Gearin-Tosh, Living Proof: A Medical Mutiny (Get the book.)
| "Even the human genome Project researchers align with this 80% determination, stating that genes are only a part of the story. The book Genetic Nutri-tioneering: How You Can Modify Inherited Traits and Live a Longer, Healthier Life by Jeffrey S. Bland, PhD, shows that scientists now have a huge amount of evidence that many diseases previously attributed to "bad genes" are now known to be caused by a bad diet that "feeds the genes," affecting them for the worse.
Genetic or congenital patients probably account for 5% or much less of medical doctor and hospital case files in recent times." - Susan E. Schenck, The Live Food Factor: The Comprehensive Guide to the Ultimate Diet for Body, Mind, Spirit & Planet (Get the book.)
| "By the 1990s the human genome project, the $3 billion venture to map the entire human genome, had been launched, with a draff completed in 2000. Genetics has become a cutting edge of medical knowledge and has moved to the center of medical and public discourse about illness and health (Conrad, 1999). The biotechnology industry has had starts and stops, but it promises a genomic, pharmaceutical, and technological future that may revolutionize health care (see Fukuyama, 2002)." - Peter Conrad, The Medicalization of Society: On the Transformation of Human Conditions into Treatable Disorders (Get the book.)
| "The full code of the DNA for a particular type of organism is called a genome. The human genome contains about 3 billion base pairs or a total of 6 billion bases in the double-stranded DNA.
Functional units, which make up only a small percentage of the DNA in plants, animals, and humans, are sequences called genes. Genes code for proteins. In the human genome, genes comprise only about 3% of the DNA. The other sequences are non-coding. The number of genes in a genome varies a great deal. Humans have about 25,000 genes, but the exact number is still being determined." - Jeffrey M. Smith, Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods (Get the book.)
| "A draft of the human genome was published in 2001.
Huntington's Disease. A degenerative brain disorder, caused by a single dominant gene, that usually appears in mid-Life. Its symptoms, which include involuntary movement of the face and limbs, mood swings, and forgetfulness, get worse as the disease progresses. It is generally fatal by age 60.
Index (Experimental) Group. A group of people diagnosed with the psychiatric disorder in question, and their relatives. Usually compared to a control group consisting of people not diagnosed with the disorder, and their relatives." - Jay Joseph, The Missing Gene: Psychiatry, Heredity, and the Fruitless Search for Genes (Get the book.)
| "A pseudogene is a gene copy that does not produce a functional, full-length protein. The human genome is estimated to contain up to 20,000 pseudo-genes____Their biological roles remain largely unknown."62
A study in Nature confirmed that a gene insert into mouse DNA altered the expression of a nearby pseudogene, which in turn altered the activity of regulatory RNA.
According to INBI, "The same dsRNA can have physiologically different effects63 at different concentrations."64 It is not always clear in advance which gene the dsRNA will affect. " - Jeffrey M. Smith, Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods (Get the book.)
"In the human genome, genes comprise only about 3% of the DNA. The other sequences are non-coding. The number of genes in a genome varies a great deal. Humans have about 25,000 genes, but the exact number is still being determined.
When a gene is active or expressing, its code is reproduced or transcribed into separate RNA (ribonucleic acid) strands called transcripts. The transcripts can then be translated into amino acids according to a formula; specific combinations of three bases in the RNA determine which amino acids are produced."
- Jeffrey M. Smith, Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods (Get the book.)
| "Polymorphic, Pluri-Potential Genes and Individualizing Your Diet
This important concept begins to emerge from the research done in the human genome project, as outlined by Jerry Bishop and Michael Wald-holz in their book Genome, which describes this breakthrough.39 The human genome project makes the point that genes are only one part of the story. More important than genetic inheritance is the phenotypic expression. This is the part where we have a choice." - Gabriel Cousens, M.D., Spiritual Nutrition: Six Foundations for Spiritual Life and the Awakening of Kundalini (Get the book.)
| "Paul Meltzer, MD, PhD, head, section of molecular genetics, cancer genetics branch, National human genome Research Institute.
The New England Journal of Medicine.
Scientists are learning that not all melanoma skin cancers are genetically alike. And that may have far-reaching implications for the treatment and prevention of this disease.
I'm somewhat optimistic now that we may turn the corner on melanoma therapy.
Paul Meltzer, MD, PhD
THE STUDY
Dr." - Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.)
| "Just a few years ago the entire human genome was mapped. Surprisingly, humans have only 30,000 genes, far less than expected. Small molecules can switch these genes on or off, called gene expression or silencing. Resveratrol is one of these small molecules.
A landmark report in Nature Magazine recently stated that most diseases involve many genes. Only one percent of diseases are single-gene disorders. Single-gene targeted anticancer drugs like Iressa (gefitinib) and Tarceva (erlotinib) have been disappointing. The report in Nature Magazine suggests drugs be used that target many genes." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.)
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