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"We have spent well over a billion dollars on the research and development of these hrt medical preparations, and all we get is some apparent pluses and probably even more minuses. Calling this troubling doesn't begin to describe it. Instead of relying on hrt, I suggest that there is a better way, using food. The argument goes like this: • During the reproductive years, hormone levels are elevated, although the levels among women who eat plant-based diets are not as elevated." - T. Colin Campbell, Ph.D. and Thomas M. Campbell II, The China Study: The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications for Diet, Weight Loss and Long-term Health (Get the book.)

"MTHFR polymorphisms, diet, hrt, and breast cancer risk: The multiethnic cohort study. Cancer Epidemiol. Biomarkers Prev. 13, 2071-2077. 15. Ann, J., Gammon, M. D., Santella, R. M., et al. (2006). Effects of glutathione S-transferase Al (GSTA1) genotype and potential modifiers on breast cancer risk. Carcinogenesis 27, 1876-1882. 16. Xu, X., Gammon, M. D?Wetmur, J. G, et al. (2007). A functional 19-base pair deletion polymorphism of dihydrofo-late reductase (DHFR) and risk of breast cancer in multivitamin users. Am. J. Clin. Nutr. 85, 1098-1102. 17. McCullough, M. L., Stevens, V. L., Diver, W." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"The often used allopathic treatment for female hormonal problems is to prescribe synthetic estrogen hormone replacement therapy, hrt, which further increases estrogen dominance. The answer that Dr. Lee arrived at was to treat typical hormone problems with natural progesterone. Estrogen Mimics Other hormone disrupter problems in our society, in addition to synthetic hormones, are xenoestrogens or xenobiotics, which produce estrogen-like activity in the body." - Ron Garner, Conscious Health: A Complete Guide to Wellness Through Natural Means (Get the book.)

"Based on these findings, there is no role for hrt in heart-disease prevention. SOY A natural product that has been promoted as a preventative for heart disease, soy is a vegetable protein present in tofu, a food widely consumed in Asia. It is also sold in health-food stores as a supplement for that purpose. Studies have found that replacing animal fat with soy results in a reduction of LDL cholesterol of 13%.50 If you want to reduce your intake of animal fat, soy and other legumes (beans) are a good alternative source of protein." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.) "They are probably preferable to the synthetic and animal preparations and might have fewer negative health consequences; however, we can't say that they don't cause the cancers and other negative health consequences that have been shown with hrt. Since they are the same thing, I suspect they do. HERBS AND SUPPLEMENTS Studies of herbs and supplements for the treatment of hot flashes have not shown consistent results. Soy, black cohosh, dong quai root, and evening primrose oil have all been promoted for hot flashes." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.) "However, exercise, especially weight and strength training, have other beneficial effects, like preventing osteoporosis-related fractures, helping to make up some of the benefit lost from not taking hrt. High-fat, low-fiber diets are associated with higher estrogen activity. Since Asian women tend to have lower levels of estrogen before (and after) menopause, the drop in estrogen levels they experience in menopause may be less dramatic, resulting in milder symptoms at menopause or none at all." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.) "So called "natural" female hormones, like estrogenlike compounds derived from plants, if they have any active properties, will also have the negative properties of hrt and therefore should not be used. I do recommend use of SSRIs, clonidine, or gabapen-tin for hot flashes if needed, since these drugs are safe and nonaddictive and have been shown in clinical trials to reduce hot flashes." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"Interestingly, these studies did show that those taking hrt experienced a significant decrease in LDL (bad) cholesterol and a significant increase in HDL (good) cholesterol. So why did these patients have an increased risk of heart disease? I believe the answer appeared in other studies that have shown women who take synthetic hrt had a tremendous increase in their C-reactive proteins, which you may recall is a measure of the inflammation in the artery. It is a much better predictor of future heart attacks than is cholesterol—especially in women." - Ray D. Strand, What Your Doctor Doesn't Know About Nutritional Medicine May Be Killing You (Get the book.)

"For us, the story of ERT, and then the almost repeat story of hrt, is frustrating. Numerous clinical studies show that there is little or nothing to be gained from estrogen treatments, and much to be lost. Yet a confluence of interests—pharmaceutical companies pushing drugs for diseases that they invented, professional imperialism, and the cultural stereotyping of aging women—has too much momentum to stop. This is not an example of bad science so much as an example of inappropriate and even dangerous medical practice." - Gerald E. Markle and Frances B. McCrea, What If Medicine Disappeared? (Get the book.)

"More About hrt and Breast Cancer. The issue of progestogens and breast cancer is complex and not very well understood. It is difficult to come to a comfortable conclusion on this matter. One of the largest studies to date, the Nurses' Health Study, showed that adding a synthetic progestin to estrogen failed to reduce the incidence of breast cancer and actually increased it." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"Concerns about safety and effectiveness are causing a retreat from the blanket use of hrt. An estimated 30%-45% of women who receive prescriptions for hrt will not have their prescriptions filled or will discontinue therapy within 12 months of initiation.7 Crucial link between Cholesterol, Magnesium and Hormones It is impossible to consider estrogen and progesterone in isolation from other hormones and from precursors like cholesterol and magnesium. All steroid hormones are createdfrom cholesterol in a hormonal cascade." - Mark Sircus, Transdermal Magnesium Therapy (Get the book.)

"Hormone Support Therapy Hormone replacement therapy, or hrt, which was the main form of hormone therapy in the past, never made sense to me. Why replace hormones when you can support them naturally? Natural hormones (or bioidentical hormones) are identical to those found in nature. They look and act exactly the same as hormones that are made naturally in our bodies. They are not something new or foreign working in your body. Your own hormones are not replaced by synthetic, stronger-acting hormones. Women's hormones should certainly not be replaced by horse hormones." - Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

"This is absolutely not the place to get into the enormous controversy generated by preliminary findings from the Women's Health Initiative that reported a slightly increased risk of heart attacks and breast cancer for women on hrt. I just want to point out two things and then urge you to speak to a knowledgeable healthcare practitioner about them: One, the findings are controversial, and may apply only to women who started taking the hormones later in life." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.) "The 30-Day Natural Hormone Plan: Look and Feel Young Again—Without Synthetic hrt by Erika Schwartz, M.D. Schwartz is a really smart endocrinologist and one of my favorite hormone specialists on the East Coast. This is her program. Get Off the Menopause Roller Coaster: Natural Solutions by Shari Lieberman, Ph.D. Out of print, but if you can find it, grab it! Before the Change: Taking Charge of Your Perimenopause by Ann Louise Gittleman, Ph.D. Wonderful advice on diet and lifestyle for the premenopausal woman by the First Lady of Nutrition!" - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Most of the experts say that this kind of hormone replacement therapy—they call it 'HRT'—raises the risk of cancer. Some say it's a slight added risk, some say it's more than that. My gynecologist says that when Provera—he calls it progesterone—is part of hrt, then the risk is lessened again." "Does your family have any history of heart attack or perhaps osteoporosis?" "Both. That's another reason I'm thinking that the vitamins and herbs might not be enough. Mother had a heart attack when she was 68, and another at 73." - Jonathan V. Wright, M.D. and Alan R. Gaby, M.D., Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing (Get the book.)

"In the five years since the WHI, many studies have been completed, shedding new light on why decades of observational studies of postmenopausal women using hrt differed from the WHI study and why there seems to be such disparity amongst some of the key studies in the area of memory, heart disease, and breast cancer in particular. While reviewing each of these studies would be informative, I would like to summarize and utilize the 2007 position statement of the North American Menopause Society (NAMS) and its expert advisory panel of clinicians and experts in the field of women's health." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"The important lessons from this chapter of American medical history will be lost if we simply attribute the debacle of routine hrt for healthy postmenopausal women to the vagaries of medical progress. Failure to understand how this mistake occurred commits us (doctors and patients alike) to being naively swept up by each new cycle of exaggerated claims about the effectiveness and safety of ever more expensive medical therapies—that is, until even newer "medical knowledge" is produced that supports even costlier drugs." - John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"These results are the opposite of those seen in the Nurses' Health Study—women who are using hrt for more than five years have the increase in risk.164 Two other recent studies, the Carolina Breast Cancer Study170 and analyses from the National Health and Nutrition Examination Survey (NHANES),171 found no increased risk with postmenopausal hormones. These recent studies perpetuate the inconsistency in research on this issue that has been true in the last 25 years." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"Few want to gamble on hrt, even in lower doses—especially since claims of protective effects against heart disease and dementia have turned out to be untrue.5 In fact, the very latest research suggests that hrt actually raises the risk of heart disease and dementia.8'9 But if not hrt to manage menopause, then what? A growing number of women are turning to natural remedies—such as the plant estrogens in soy, black cohosh (Cimicifuga racemosa), and chasteberry or vitex (Vitex agnus-castus)—to ease the menopausal transition." - Richard P. Brown, M.D., and Patricia L. Gerbarg, M.D., The Rhodiola Revolution: Transform Your Health with the Herbal Breakthrough of the 21st Century (Get the book.)

"Brain MRI studies have shown that the longer the duration of hrt, the better the brain tissues looked (less shrinkage of white and gray matter). Breast Cancer Fears Breast cancer is the most common reason that women refuse to use hormones, but what many women don't realize is that their body continues to make estrogen long after menopause. Deciding not to use any estrogen support does not protect a woman from breast cancer; many studies have clearly shown that. The older a woman is (and the lower her estradiol levels are), the more likely she is to get breast cancer." - Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

"Women's Health Initiative hrt Randomized Controlled Trial Health Outcome Relative Risk Absolute Risk (events per 10,000 people per year) Heart disease 29 percent increase 7 more Invasive breast cancer 26 percent increase 8 more Stroke 41 percent increase 8 more Pulmonary embolism 113 percent increase 8 more Hip fracture 34 percent decrease 5 less Colorectal cancer 37 percent decrease 6 less Source: Adapted from the Writing Group for the Women's Health Initiative Investigators (2002) and Fletcher and Colditz (2002). a year." - Nortin M. Hadler MD, Worried Sick: A Prescription for Health in an Overtreated America (Get the book.)

"Still, hrt is not advised for everyone—ask your doctor about your case. powerful a remedy black cohosh can be. It should be taken in small doses, and although it's a good, natural painkiller, it should not be used during pregnancy. Note: Remifemin, a packaged product containing compounds from the black cohosh plant, is now available in the US. It costs approximately $30 for a one-month supply. It has been sold in Europe for years." - Bottom Line Books, Uncommon Cures For Everyday Ailments (Get the book.)

"If women who take estrogens have a lower risk for AD prior to talcing hrt because they are healthier than the group not taking hrt, it is difficult to fully evaluate the protective role of hrt, especially in light of possible increased risk for breast cancer with hrt therapy (see Menopause). Some clinical trials have indicated that estrogen therapy improves mental function, but other studies have not supported those results.15"18 It is likely that estrogen produces some benefits, but several natural products discussed in this chapter exert greater benefit without the risk of breast cancer." - Michael T. Murray, N.D., Joseph E. Pizzorno, N.D., Encyclopedia of Natural Medicine, Revised Second Edition (Get the book.)

"Letronex, a drug to treat irritable bowel syndrome in women, was withdrawn by the manufacturer Smith Kline in 2000, because of some fatal cases. • hrt (Hormone Replacement Therapy) found to be dangerous for women who have coronary heart disease (CHD). Thromboembolism295 and gallbladder disease can follow.296 • High doses of Vioxx, which we mentioned already, triples risks of heart attacks and sudden cardiac death.297 • In the year 2004, eighty thousand people went to emergency rooms with prescription drug overdoses (usually tranquilizers, like Valium and sedatives)." - Kenneth W Thomas, Ron Gilbert, Gerd Schaller, Side Effects: The Hidden Agenda of the Pharmaceutical Drug Cartel (Get the book.)

"The latest study from the National Cancer Institute, reported in the Journal of the American Medical Association in January 2000, showed that women who used hrt sustained an even greater risk for developing breast cancer than women taking estrogen alone (see more on this study in Chapter 10) .30 According to Dr. Christiane Northrup, this is because commonly used progestins—Provera (medroxyprogesterone acetate, or MPA), norethisterone, and norgestero—have androgenic activity, which can further stimulate breast cells." - Linda Ojeda, Menopause Without Medicine: The Trusted Women's Resource with the Latest Information on hrt, Breast Cancer, Heart Disease and Natural Estrogens (Get the book.) "HRT, has developed a tri-estrogen formula containing all three estrogens in a balanced ratio closely replicating that in a woman's body: estriol (80 percent), estradiol (10 percent), and estrone (10 percent). He and others have been using this recipe for almost 20 years and have found it very effective for the variety of menopausal symptoms. All of the natural hormones that Dr. Wright uses are derived from the Mexican wild yam (Diascorea)." - Linda Ojeda, Menopause Without Medicine: The Trusted Women's Resource with the Latest Information on hrt, Breast Cancer, Heart Disease and Natural Estrogens (Get the book.)

"HRT does not prevent heart disease. hrt is effective for menopause symptoms (used short term), and helps protect against osteoporosis and colon cancer. Other treatments are available for osteoporosis. Discuss with your doctor if hrt is the right treatment for you. • May interfere with the accuracy of some medical tests. • Carefully read the paper called "Information for the Patient" that was given to you with your first prescription or a refill. If you lose it, ask your pharmacist for a copy. • Advise any doctor or dentist whom you consult that you take this medicine." - H. Winter Griffith, M.D., Complete Guide to Prescription and Nonprescription Drugs 2005 (Get the book.)

"One of the theories from rodent research is that with long-term hrt, estrogen receptors in the brain begin to break down in the hypothalamus, the area that activates the immune response. And if the hypothalamus is not working correctly, women would be more vulnerable to diseases such as cancer. Equally important, long-term estrogen treatment in rodents also causes cellular inflammation, which is a risk factor for Alzheimer's and is associated with memory impairment." - John J. Ratey, MD, Spark: The Revolutionary New Science of Exercise and the Brain (Get the book.)

"Some researchers believe that the negative effects of hrt are due to the fact that they are synthetic products and therefore not well received by the human body. It is thought that natural hormones may not elicit such troublesome outcomes because they are recognized by the body. Many women find that natural hormones do not come with the same offensive side effects and may be a better option than the synthetic versions. Furthermore, many women are not told that hormone treatment can be used short term." - Linda Ojeda, Menopause Without Medicine: The Trusted Women's Resource with the Latest Information on hrt, Breast Cancer, Heart Disease and Natural Estrogens (Get the book.)

"As a result, hrt is no longer considered advisable as a first-line preventive or treatment measure for health problems in women. Thus, the Solbar Plant Extracts company advertises a soy isoflavone ingredient as "Clearly a healthy solution . . . Nature's remedy to hrt." Soy foods may be used as a natural remedy for hot flashes but despite vast amounts of research, it is unclear how effective they are for treatment or prevention of this or any other condition. Soy companies and trade associations—the USDA-sponsored United Soybean Board and Illinois Soybean Checkoff Board, Dr." - Marion Nestle, What to Eat (Get the book.)

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