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NaturalPedia > Hormones and Biochemistry > Homocysteine
Quotes about Homocysteine from the world's top natural health / natural living authors
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"Too much homocysteine is a major promoter of arterial damage. Moreover, the homogenization of milk creates very small compounds that get inside blood vessels, causing inflammation and injury to the vessel walls.
The Pan-Asian Mediterranean diet emphasizes fish for its lean, healthy protein and anti-inflammatory oils." - Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)
| "One lead suggested that blood homocysteine levels were important, another that blood lipid levels were the critical factor. The homocysteine hypothesis suggested a range of dietary approaches... such as taking folate or B vitamins. The lip id-lowering approach gave rise to a generation of patented drugs" which are "among the most profitable agents ever made. Rival evidence for homocysteine was effectively buried for almost 30 years." (He cites the prestigious journal The Lancet No. 354." - Helke Ferrie, Dispatches From the War Zone of Environmental Health (Get the book.)
| "Most doctors prescribe vitamin combinations of vitamins B6 (100 mg/day), BJ2 (1,000 mg/day), and folic acid (1 to 2 mg/day). If homocysteine levels remain elevated after two or three months of such therapy, I recommend polymorphic genetic testing (discussed at the end of this chapter) to see which enzymes are having trouble. Some women need very high doses (2 to 16 mg) of folinic acid or methylated folic acid, glutathione (from NAC, N-acetylcysteine), methionine, or betaine (trimethylglycine), or injections of high-dose methylated Bl2." - Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)
"Vitamin D (25-hydroxy vitamin D): If it's too low, you are at increased risk of bone loss (less than 30 ng/ml, although many sources recommend levels above 50 ng/ml).
• Homocysteine: Measures how well your body is methylating. If levels are too high, you are at risk for heart disease and may have difficulty breaking down your estrogen. Some physicians recommend taking 1000 to 1500 mg methionine six hours before the blood test, because homocystiene levels may be (falsely) low if you are deficient in methionine."
- Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)
"To assess your heart disease risk factors, have your doctor order a thyroid screen, fasting lipid profile, CRP, homocysteine, and a diabetic screen with a HBA1C (hemoglobin A1C).
• All women (and their men friends) should have a colonoscopy by age fifty.
Is Estrogen Really Safe, Really?
Although I discussed hormone safety in chapter 3, here we are again. It's like that with my patients when the topic of estrogen comes up. Progesterone doesn't usually raise too many eyebrows, but the minute I mention estrogen I see the worry lines, literally."
- Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)
"They can perform many of the routine blood tests mentioned throughout this book, such as RBC magnesium, homocysteine, CRP, DHEA-S, all hormone levels, SHBG, and IGF-1. They also offer specialized tests such as CoQIO levels and vitamin A and vitamin E levels, so be sure to ask your doctor if he or she uses Quest or a comparable lab.
Rhein Consulting Laboratories
4475 SW Scholls Ferry Road, Suite 101
Portland, OR 97225
Phone: 503-292-1988 www.rheinlabs.com
Rhein Consulting Laboratories does excellent and affordable twenty-four-hour urine tests for all hormone metabolites."
- Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)
| "In New Cardiology, we check cholesterol, but we are more concerned about homocysteine, a troublesome substance that builds up in the body if you're short of certain vitamins, creating inflammation and sticky blood. We want to check substances called Lp(a), fibrinogen, ferritin, and C-reactive protein (CRP). We want to determine the calcium score in your coronary arteries—a new measurement that predicts heart attack risk better than traditional tests.
You may not have heard about these things before." - Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)
| "Folic acid and vitamins B]2 and B6 are co-factors in homocysteine's metabolic pathways, and their presence in the body may potentially lower levels of this substance. This has prompted some physicians to recommend the three vitamins as supplements. Proof is lacking in the form of randomized controlled trials, although a recently published study appears to have confirmed the effect of folic acid supplementation on cognitive performance in human beings. Jane Durga et al." - Peter J. Whitehouse and Daniel George, The Myth of Alzheimer's: What You Aren't Being Told About Today's Most Dreaded Diagnosis (Get the book.)
| "He was tested for New Cardiology risk factors and had them aplenty: elevated fibrinogen, homocysteine, an off-the-chart Lp(a) of 93, lead and mercury, insulin resistance, and low free testosterone.
Doug still refused bypass. He was then started on a supplement program, including CoQIO, L-carnitine, antioxidants and minerals, nanobacteria therapy, and heavy metal detoxification. Later on, L-arginine and pellet testosterone therapy were added.
Doug's symptoms disappeared. His HDL went up and LDL went down.
Less than a year later, he was able to walk nine minutes on the treadmill." - Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)
| "The primary way that methyl-B-12 helps methylation is by enabling homocysteine to make methionine. Methionine is a key element in the methylation process. In addition to improving detoxification, other benefits of enhanced methylation include: improved cell membrane function, improved neurotransmitter and hormone metabolism, and improved neuronal healing.
Methyl-B-12 is very highly rated in the ARI parent survey:
Symptoms improved: 63 percent. ?" - Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.)
"Indicators that TMG may be needed include:
• High homocysteine.
• Low methionine. High serum folate.
In the ARI parent survey, TMG and DMG, rated together, were evaluated as follows:
Symptoms improved: 42 percent No discernible effect: 51 percent Symptoms worsened: 7 percent
My general recommendation: DMG: 125 to 1,000 mg. per day; TMG: 175 to 2,000 mg. per day, depending upon age, size, and other treatments and indications.
Vitamin D. Only in the past few years has vitamin D begun to be fully appreciated."
- Kenneth Bock, Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders (Get the book.)
| "Elevated levels of the amino acid homocysteine are associated with increased risk of heart attack, but it is not yet clear whether elevated homocysteine causes heart disease or heart disease causes elevated homocysteine. However, supplementation with a combination of folic acid, vitamin B6 (pyridoxine), and vitamin B12 (cobalamin) reduces homocysteine levels and may lower the risk of heart attack.
J Niacin is a proven, low-cost treatment for preventing second heart attacks. The drawback to using niacin is that it causes the face to flush twenty to thirty minutes after it is taken." - Phyllis A. Balch, CNC, Prescription for Herbal Healing: An Easy-to-Use A-Z Reference to Hundreds of Common Disorders and Their Herbal Remedies (Get the book.)
| "Shai I, Stampfer MJ, Ma J, Manson JE, Hankinson SE, Cannuscio C, Selhub J, Curhan G, Rimm EB. homocysteine as a risk factor for coronary heart diseases and its association with inflammatory biomarkers, lipids and dietary factors. Atherosclerosis. 2004 Dec;177(2):375-381.
67. Sengul E, Cetinarslan B, Tarkun I, Canturk Z, Turemen E. homocysteine concentrations in subclinical hypothyroidism. EndocrRes. 2004 Aug;30(3):351-9.
Chapter 22
1. This is a good review of Codex and US law. Harris, JD, Suzanne. Who Says Whatever Happens at Codex Does Not Affect US Law And Why Do They Say It? The Law Loft." - Byron J. Richards, Fight for Your Health: Exposing the FDA's Betrayal of America (Get the book.)
| "The benefits of reducing homocysteine are not yet established, but the steps that reduce it are all healthful, so here is how to go about it.
Certain vitamins—folic acid and vitamins B6 and B12—help to eliminate homocysteine. You will find plenty of folic acid and vitamin B6 in beans, vegetables, and fruits; plant-based food sources of B12 are limited to supplemented products such as fortified soy milk and cereals (e.g., Total, Product 19, and Kellogg's Corn Flakes), nutritional yeast, and a few other foods." - Neal D. Barnard and Bryanna Clark Grogan, Dr. Neal Barnard's Program for Reversing Diabetes: The Scientifically Proven System for Reversing Diabetes Without Drugs (Get the book.)
| "One lead suggested that blood homocysteine levels were important, another that blood lipid levels were the critical factor. The homocysteine hypothesis suggested a range of dietary approaches... such as taking folate or B vitamins. The lip id-lowering approach gave rise to a generation of patented drugs" which are "among the most profitable agents ever made. Rival evidence for homocysteine was effectively buried for almost 30 years." (He cites the prestigious journal The Lancet No. 354." - Helke Ferrie, Dispatches From the War Zone of Environmental Health (Get the book.)
| "Vitamin B6, B12 and folic acid work to decrease homocysteine levels.
Calcium and Magnesium
Calcium and magnesium are useful for people using steroids because they decrease bone mass. It is also one of the more difficult minerals to absorb. However, calcium citrate tends to be better absorbed than carbonate. However, calcium carbonate was studied and is thought to prevent colon cancer. This is likely because it is not absorbed well and binds intestinal toxins and excretes them. One can take up to 1,200 mgs of calcium with 600 mgs of magnesium daily." - Heather Caruso, Your Drug-Free Guide to Digestive Health (Get the book.)
| "You may need to take extra folic acid, vitamin B-6, and vitamin B-12 if you have elevated homocysteine. Take extra niacin if you have low HDL.
A multi usually has vitamin E in it, but we recommend you take a full-spectrum vitamin E supplement containing mixed tocopherols, preferably with tocotrienols.
We recommend high-allicin forms.
Available in early 2007 in health food stores and online at www. drsinatra.com.
For individuals with high Lp(a), rapid disease progress and blockages, and repeated cardiovascular events." - Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)
| "To compound matters, without B vitamins, your homocysteine levels rise, and that doubles the risk of developing Alzheimer's. homocysteine is an amino acid associated with stroke, heart disease, and Alzheimer's. Although no study has demonstrated a benefit of supplementation to your thinking process, the products are generally safe, and anecdotal evidence is enticing. We recommend a supplement with 400 micrograms of folic acid, 800 micrograms of B,2, and 40 milligrams of B6 a day." - Mehmet C. Oz., M.D. and Michael F. Roizen, M.D., You: Staying Young: The Owner's Manual for Extending Your Warranty (Get the book.)
| "In one study, 276 healthy people over age sixty-five with elevated homocysteine concentrations were given folate and vitamins B12 and B6 or a placebo. Neither folate nor vitamin B supplementation resulted in an improvement in scores of cognition after two years.21
GINKGO BILOBA
Ginkgo biloba, a supplement derived from the ancient ginkgo tree of China, has long been believed to increase memory, energy, and concentration. It is also used to treat tinnitus and vascular disease. Many consider ginkgo a neuroprotective agent as well as an antioxidant." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)
| "The highest total dietary fiber and nonsoluble dietary fiber (more than soluble) intakes from fruit, vegetables, and cereals were significantly associated with a decrease in a number of cardiovascular risk factors including overweight, hypertension, lipid markers, and homocysteine.87 Part of fiber's effect on lipids is because these higher fiber diets are in fact diets low in cholesterol intake.88
Another study found that soluble fiber added simply as a breakfast bread source was found to significantly decrease blood pressure and triglyceride and cholesterol levels in diabetic patients." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)
| "This is particularly important because one study found that people with high levels of homocysteine were at an almost three times greater risk for Alzheimer's disease than those with low levels.
A regular 12-ounce cafe latte supplies 400 mg of calcium. You can get even more calcium, and less fat and calories, by using low-fat or fat-free milk.
Other researchers have found B6 also helps lower homocysteine. Still others discovered that B12 and thiamin, another B vitamin found in whole grains, nuts, and beans, help carry messages quickly to and from your brain.
Calcium." - The Editors of FC&A, Unleash the Inner Healing Power of Foods (Get the book.)
"The homocysteine-lowering effect of folate probably helped. homocysteine is a dangerous substance that encourages blood clots and hardening of the arteries. But vitamin B6's ability to stop platelets from clumping could have had something to do with it, too.
Studies often use supplements that give you more B vitamins than you get from your diet. But you can get plenty of these vitamins from foods. Here's where to look.
• Vitamin B6 can be found in dark leafy greens, seafood, legumes, whole grains, fruits, and vegetables.
• Vitamin B12 appears in meats, fish, dairy foods, and eggs."
- The Editors of FC&A, Unleash the Inner Healing Power of Foods (Get the book.)
| "HEART HEALTH: Corn is high in folate, a vitamin known to reduce homocysteine, an inflammatory marker attributed to heart disease.
LUNG CANCER: Corn is rich in beta-cryptoxanthin, an orange-red carotenoid that may significantly lower the risk of developing lung cancer. One study evaluated the diet of 63,257 adults in Shanghai, China, finding that those who ate the most crytpoxanthin-rich foods had a twenty-seven percent reduction in lung cancer risk. Smokers who ate the crytopoxanthin-rich foods were found to have a thirty-seven percent reduction in risk compared to those who didn't eat them." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)
"Asparagus is an excellent source of folic acid, which may help control homocysteine, a risk factor for heart disease, cancer, and cognitive dysfunction, and also may reduce birth defects. Asparagus is also a good source of vitamin C, thiamine, and vitamin B6. It is also high in rutin, a flavonoid that is thought to have anti-inflammatory properties, strengthen blood vessels, and protect against oxidative damage.
Asparagus is also high in glutathione, an antioxidant that protects cells from damage."
- David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)
"A rise in homocysteine can significantly increase the risk for heart disease by promoting atherosclerosis. Just one serving of asparagus supplies almost sixty percent of the daily recommended intake of folate.
Tips on Using Asparagus
SELECTION AND STORAGE:
• Select bright green asparagus with closed, compact, firm tips.
• If the tips are slightly wilted, freshen them up by soaking them in cold water.
• Keep fresh asparagus moist until you intend to use it.
• Asparagus can be frozen but it is better not to defrost it before cooking."
- David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)
| "Tests for lipoprotein (a), C-reactive protein, fibrinogen, homocysteine, and subfractions of HDL-C and LDL-C are a few of the more frequently used. It is difficult to say with certainty, at this time, in whom and how often these should be done. Currently, the scientific community has not agreed on guidelines for their use or whether such testing ultimately does a better job than the traditional physical exam with cholesterol panels and blood glucose testing." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)
| "Kaare Harald Bonaa, MD, PhD
"Combination vitamin therapies, which do lower homocysteine, have no effect on cardiovascular events, even though the homocysteine level is lowered," says Dr. Joseph Loscalzo, head of the department of medicine at Brigham and Women's Hospital in Boston.
THE FIRST STUDY
In the first study, called the Norwegian Vitamin (NORVIT) trial, Norwegian researchers randomly assigned 3,749 men and women who had had heart attacks to receive either folic acid along with vitamins B-6 and B-12, or a placebo." - Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.)
| "A more recent commercially available product, hemp seed and hemp seed oil, may also prove to be beneficial in the lowering of lipids, homocysteine, CRP, and others. Evening primrose oil rich in gamma-linolenic acid (GLA) may also have a role in prevention of heart disease283 by decreasing LDL cholesterol.
Fish Oil
1 g per day of EPA and DHA 2-4 g per day of EPA plus DHA may be useful in patients with elevated triglycerides
Wild salmon ranges from 1.0-1.5 g EPA plus DHA per 3 oz serving, with a little more DHA than EPA. Different species range in their EPA and DHA content." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)
| "Homocysteine has been implicated in the formation of atherosclerosis, directly damaging the artery and affecting the blood-vessel wall, interfering with the formation of collagen.
Elevated homocysteine levels are a definite independent risk factor for heart attack, stroke, and other vascular disorders. Abnormal homocysteine levels are found in nearly 40 percent of patients with heart disease.
Taken from R. Clarke et al., "Hyperhomocysteinemia: An independent Risk Factor for vascular Disease," New England Journal of Medicine 324 (1991),
PP. 1149-55." - James F. Balch, M.D., The Super Anti-Oxidants: Why They Will Change the Face of Healthcare in the 21st Century (Get the book.)
| "Plasma homocysteine in Acute Myocardial Infarction: Homocysteine-lowering Effect of Folic Acid," Journal of Internal Medicine, 237(4), April, 1995, p. 381-388.
Results of this study showed that the administration of 250 mg per day of vitamin B6 and 5 mg of folic acid for 6 weeks normalized homocysteine metabolism in young patients with arterial occlusive disease.
—M. van den Berg, et al., "Combined Vitamin B6 Plus Folic Acid Therapy in Young Patients with Arteriosclerosis and Hyperhomocysteinemia," Journal of Vascular Surgery, 20(6), December 1994, p. 933-940." - Gary Null, Ph.D., The Clinician's Handbook of Natural Healing (Get the book.)
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