Quotes about Gleevec from the world's top natural health / natural living authors
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 "Nor was the report on the front pages of the New York Times that chose instead to extol gleevec, a disappointing anti-cancer drug that costs $2,500 for a month of treatment. Instead, the media ignored this report which said that a 5-cent pill, heralded by independent researchers, appears to be the biggest cancer breakthrough in history.
The report, published in the February 2006 issue of the American Journal of Public Health, did not reveal anything new, but rather tabulated results from scientific reports conducted over the past 40 years that public health authorities had ignored."- Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.) "It is a more promising anti-breast cancer agent than the currently used gene-targeted drugs like gleevec or Er-bitux. [Current Drug Targets 7: 423-42, 2006] See the section in this book on resveratrol. Ginseng and breast cancer Researchers in China were surprised to find, in a recently conducted survey of over 1,000 women diagnosed with breast cancer, that ginseng may have some beneficial properties for women. Compared with patients who never used ginseng, regular users had a significantly reduced risk of death (~29% relative risk reduction) and had better psychological and social well-being." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.) "Avastin, Erbitux, gleevec... The new wonder drugs might make you think we're finally beating this dreaded scourge. We're not. - Clifton Leaf Fortune Magazine, March 9, 2004 Yet, the gene targeted drugs go on being extolled. "Stunning," "revolutionary," "jaw-dropping," "wonder drug," "cuts disease recurrence in half," are the words used to describe the three reports published in the New England Journal of Medicine involving Herceptin (trastuzumab)." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.) "Gleevec ended up influencing other genes. Bryan Roth, a biochemist at Case Western Reserve University in Cleveland, says "magic shotguns" rather than "magic bullets" are what's needed. Simon Frantz, writing the lead article in an issue of Nature Magazine, says: "Forget drugs carefully designed to hit one particular molecule - a better way of treating complex diseases such as cancer may be to aim for several targets at once." - Bill Sardi, You Don't Have to be Afraid of Cancer Anymore (Get the book.) |
 "A drug called gleevec (formeraly known as STI 571) is a protein-tyrosine kinase inhibitor that specifically interferes with the Bcr-Abl tyrosine kinase—the typical chromosomal abnormality seen in chronic myeloid leukemia (CML). gleevec inhibits proliferation and induces apoptosis in Bcr-Abl cell lines as well as fresh leukemic cells from "Philadelphia chromosome positive" chronic myeloid leukemia (CML). gleevec may also inhibit growth of other types of cancer cells."- The Life Extension Editorial Staff, Disease Prevention and Treatment (Get the book.) |
 "Product Information: gleevec (imatinib mesylate). Novartis Pharmaceuticals, East Hanover, NJ; 2003.
Product Information: Imitrex (sumatriptan tablets). Glaxo Wellcome Inc, Research Triangle Park, NC; 1999.
Product Information: Maxalt-MLT (rizatriptan benzoate orally disintegrating tablets). Merck & Co, West Point, PA; 1998.
Product Information: Ortho Evra (norelgestromin/ethinyl estradiol). Ortho-McNeil Pharmaceutical, Inc, Raritan, NJ; (PI revised 11/2001) reviewed 3/2002.
Product Information: Prograf (tacrolimus)."- Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.) |
| "To read about the latest findings on gleevec, log on to a special website www.gleevec.com.
It is interesting to note that a drug that functions along a similar mechanism as certain dietary supple-ments was put on the FDA's "fast-track" for approval.
CONCLUSION
Leukemia, Hodgkin's lymphoma, and non-Hodgkin's lymphoma generally respond well to conventional therapies. There are many different types of these diseases; therefore, chemotherapy and radiation therapy are individualized." - The Life Extension Editorial Staff, Disease Prevention and Treatment (Get the book.) |
 "Let's look at the pricing of Taxol and gleevec.
When it came on the market, Taxol sold for $10,000 to $20,000 for a year's treatment—reportedly a twentyfold markup over manufacturing costs. Bristol-Myers Squibb, you will remember, put next to nothing into the initial R&D, although it has since sponsored clinical trials aimed at expanding the uses of the drug."- Marcia Angell, M.D., The Truth About the Drug Companies: How They Deceive Us and What to Do About It (Get the book.) "He also acknowledged that the price was based partly on the price of interferon, the drug that gleevec replaced as the recommended treatment for chronic myeloid leukemia. In other words, the price was what the market would bear. In response to the outcry over the staggering price to treat this lethal disease, Novartis announced a discounting policy for patients of limited means. But according to a 2003 article in The New York Times, the plan had not worked very well so far, particularly in poor countries, where only a handful of patients have received the drug free." - Marcia Angell, M.D., The Truth About the Drug Companies: How They Deceive Us and What to Do About It (Get the book.) "Witness the initial reluctance of Novartis to undertake development of gleevec.) Nor are people with transient conditions, like most acute infections. Antibiotics, for example, seldom generate huge revenues (there are exceptions here), because while infections are common, they usually do not last very long. Lethal diseases kill the customer, so drugs to treat them are not usually blockbusters, either. Second, the market has to consist of paying customers. It doesn't help the bottom line to turn out drugs for nonpaying customers." - Marcia Angell, M.D., The Truth About the Drug Companies: How They Deceive Us and What to Do About It (Get the book.) "No one would want to be without, say, insulin for diabetes, antimicrobial agents to fight infections, vaccines to prevent a host of serious diseases, anti-clotting agents to treat heart attacks, chemotherapy for cancer, a panoply of effective painkillers and anesthetics, and many others. gleevec is a major advance, as are Epogen and Taxol. Prilosec is important, too, as are statins and ACE inhibitors and many other drugs. All of these agents have extended and greatly improved our lives." - Marcia Angell, M.D., The Truth About the Drug Companies: How They Deceive Us and What to Do About It (Get the book.) |
 "IMATINIB (i MAT in ib)
Brand Name: gleevec About Imatinib
In chronic myeloid leukemia (CML), the bone marrow produces cancerous white blood cells that, instead of defending the body against invaders, eventually fill up much of the available space in the bone marrow and crowd out other developing blood cells. In dme, these cancerous white blood cells spill over into the bloodstream.
In the early stages, CML may produce fatigue, weakness, weight loss, or other symptoms—or may not trigger any symptoms at all. But as the disease advances, a blast crisis will inevitably develop."- Frederic Vagnini, M.D. and Barry Fox, Ph.D., The Side Effects Bible: The Dietary Solution to Unwanted Side Effects of Common Medications (Get the book.) |
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