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"Green tea contains a plant compound called epigallocatechin gallate, mercifully abbreviated egcg. This compound—a member of the cat-echin family—has multiple health benefits, but one of them is that it appears to increase metabolism. Some researchers have theorized that egcg blocks the action of an enzyme that breaks down noradrenaline; noradrenaline stimulates many metabolic functions including heart rate and the release of energy from fat, so by allowing more of it to stick around, egcg may actually "boost" your metabolism." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"During each stay, the subjects ingested a capsule of placebo or capsules containing 200 mg caffeine and a variable dose of egcg (90,200, 300 or 400 mg) three times daily, 30 min before standardized meals. Twenty-four hour energy expenditure increased significantly by about 750 kJ with all EGCG-caffeine mixtures compared with placebo. No effect of the EGCG-caffeine mixture was observed on lipid oxidation. Systolic and diastolic blood pressure increased by about 7 and 5 mmHg, respectively, with the EGCG-caffeine mixtures compared with placebo." - Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.)

"The major catechins, found mostly in green tea, include: epigallocatechin-3-gallate (EGCG), epigallocatechin (EGC), epicatechin-3-gallate (ECG), and epicat-echin (EC). egcg is the most abundant and widely studied tea polyphenol, and egcg and ECG have the highest radical-scavenging activity. Caffeine levels tend to be higher in tea bag forms (the finer grind releases more caffeine) but typically range between 20 and 90 milligrams of caffeine per 8-ounce cup compared with brewed coffee's 60 to 120 milligrams." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"Some researchers have theorized that egcg blocks the action of an enzyme that breaks down noradrenaline; noradrenaline stimulates many metabolic functions including heart rate and the release of energy from fat, so by allowing more of it to stick around, egcg may actually "boost" your metabolism. And green tea contains a bit of caffeine, which may work synergistically to help get the job done. In one study, done by Abdul Dulloo, Ph.D., and his colleagues, subjects were given caffeine alone (50 mg), green tea extract plus caffeine (90 mg egcg plus 50 mg caffeine), or a placebo." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Youdim, Mandel, and colleagues have provided several extensive reviews of the properties and molecular mechanisms involved in the health benefits of egcg [187]. Thus, an extensive review will not be provided here except as these effects relate to neuroprotection, where it appears that the strongest evidence suggests that the primary beneficial properties of egcg may be its antioxidant, anti-inflammatory, and metal chelating abilities." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"They gave subjects 200 mg of caffeine together with either 90, 200, 300, or 400 mg of egcg to be taken three times a day; the control group got a placebo. They found that there was a significant increase in energy expenditure for all the EGCG-caffeine mixtures, and interestingly, the results were pretty much same for all four doses. This led the researchers to conclude that 90 mg * 3 (or 270 mg) was the "optimal concentration" to produce calorie burning." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"The most active catechin is egcg (epigallocatechin gallate), which I mention because when looking at green tea extracts, the higher the egcg content, the more potent the product. So get your caffeine from green tea, not coffee. Okay, now let me rant a bit about coffee. I am not a coffee drinker but I do realize that most of this country is fueled by it. Both coffee and tea contain antioxidants, but the coffee-roasting process destroys almost all of the antioxidant benefits." - Phuli Cohan, The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow (Get the book.)

"Green tea contains catechins (notably, epigallocatechin-3-gallate, or egcg) that reduce biochemical markers of heart disease and inhibit the oxidation of LDL cholesterol. egcg has enormous antioxidant and antiinflammatory power and inhibits prostate cancer growth and COX-2 in animal and test-tube studies. In a Journal of Nutrition report, researchers observed that the equivalent of six cups of green tea daily "significantly inhibits [prostate cancer] development and metastasis." - Freedom Press, Natural Cancer Cures: The Definitive Guide to Using Dietary Supplements to Fight and Prevent Cancer (Get the book.)

"EGCG is the most abundant and widely studied tea polyphenol, and egcg and ECG have the highest radical-scavenging activity. Caffeine levels tend to be higher in tea bag forms (the finer grind releases more caffeine) but typically range between 20 and 90 milligrams of caffeine per 8-ounce cup compared with brewed coffee's 60 to 120 milligrams." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"In this case, it appears to be the egcg in green and oolong tea and egcg along with epicatechin gallate, tannins, and theafla-vins in black tea, that play this insulin-enhancing role. This again underscores why the whole tea leaf itself and the synergy of the many nutrients are more effective than a single nutrient supplement. What about black or oolong tea?" - Wendy Bazilian, DRPH, MA, RD, Steven Pratt, MD, Kathy Matthews, Superfoods Rx Diet: Lose Weight with the Power of SuperNutrients (Get the book.)

"And one of these antioxidants is egcg, which was shown to slow the buildup of artery-clogging plaque in mice in a recent study. Green tea's abundant antioxidants may also lower total cholesterol levels by increasing intestinal excretion of cholesterol and bile acids (via your stool) and increase HDL cholesterol levels and protect against rising LDL cholesterol. In addition, green tea catechins may help the body recycle the antioxidant alpha-tocopherol (a form of vitamin E) and increase plasma blood levels of alpha-tocopherol." - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.) "EGCG (epigallocatechin gallate), which accounts for 50 to 60 percent of tea's total catechins. Most of the studies suggesting cancer-protective effects of tea have been carried out with green tea, but black tea may also have some protective qualities, just possibly less than green tea. White tea is unprocessed, so experts suspect it offers plenty of phytochemicals as well. Whether a tea is black, green, or white depends on the way it is processed. Black tea comes from leaves that have been fermented before being heated and dried." - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)

"The phytochemicals, particularly egcg in cocoa, act much the same way that other plant toxins do and their consumption similarly follows a hormetic curve. Does that mean you can gobble up milk chocolate guilt free? No way. The active ingredients in cocoa mimic the bitter polyphenols found in green tea and coffee, but all are completely inactivated by milk. That's why only very dark chocolate, as indicated by 70 percent or more cocoa content, has a beneficial effect. Raw cocoa beans and non-Dutch processed cocoa also contain these polyphenols." - Dr. Steven R. Gundry, Dr. Gundry's Diet Evolution: Turn Off the Genes That Are Killing You - And Your Waistline - And Drop the Weight for Good (Get the book.)

"Healthy young men who took two green tea capsules (containing a total of 50 mg of caffeine and 90 mg of egcg) three times a day had a significantly greater energy expenditure and fat oxidation than those who took caffeine alone or a placebo.162 In a preliminary study of moderately obese individuals, administration of a specific green tea extract (AR25) resulted in a 4.6% reduction in average body weight after 12 weeks.163 The amount of green tea extract used in this study supplied daily 270 mg of egcg and 150 mg of caffeine." - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"The increase in 24-hour energy expenditure with the EGCG-caffeine preparation was similar with all doses of egcg in the mixtures (Berube-Parent et al, 2005). Cognitive Enhancement In a double-blind, counterbalanced, placebo-controlled study of 28 healthy participants aged 18 to 24, the cognitive and mood effects of single doses of guarana, ginseng, a combination of the two, and placebo were assessed. Each sibject received 150 mg guarana dry extract, standardized to 11-13% alkaloid concentration, or 400 mg ginseng extract Gl 15, or a guarana/ginseng combination, or placebo per day." - Thomson Healthcare, Inc., PDR for Herbal Medicines, Fourth Edition (Get the book.)

"Green tea (page 686) Green tea extract rich in polyphenols (epigallocatechin gallate, or egcg) may support a weight-loss program by increasing energy expenditure or by inhibiting the digestion of fat in the intestine.160' 161 Healthy young men who took two green tea capsules (containing a total of 50 mg of caffeine and 90 mg of egcg) three times a day had a significantly greater energy expenditure and fat oxidation than those who took caffeine alone or a placebo.162 In a preliminary study of moderately obese individuals, administration of a specific green tea extract (AR25) resulted in a 4." - Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D., The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions (Get the book.)

"A clinical study confirms these findings in patients through the use of either topical application via a poly E ointment and/or oral ingesrion via a poly E or an egcg capsule." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"While there is still much to learn about the beneficial effects of green tea in relation to body weight, research findings point to two components of the tea: caffeine and the epigallocatechin gallate or egcg, which is a plant compound known as a catechin found in green tea. Originally it was simply hypothesized that the caffeine was the compound most responsible for promoting weight loss but we are now learning that green tea—as well as many black teas—has mild "thermogenic properties" beyond what can be explained by its caffeine content." - Wendy Bazilian, DRPH, MA, RD, Steven Pratt, MD, Kathy Matthews, Superfoods Rx Diet: Lose Weight with the Power of SuperNutrients (Get the book.)

"Recently, our laboratory has investigated the inhibition of IKK activity in LPS-activated murine macrophages by various polyphenols including egcg and theaflavins (Pan et al, 2000). TF-3 inhibited IKK activity more strongly than did the other polyphenols. TF-3 strongly inhibited both IKK1 and IKK2 activity and prevented the degradation of I-kB and I-kB in activated macrophage cells. These results suggest that TF-3 and other polyphenols may exert their antiinflammatory and cancer chemoprevention actions by suppressing the activation of NF-kB through inhibition of IKK activity." - Erich Grotewold, The Science of Flavonoids (Get the book.)

"Green tea happens to be loaded with a certain polyphenol catechin called egcg (epigallocatechin gallate), which has a knack for binding to a certain procancer protein, interfering with its ability to activate cancer cells, possibly stopping cancer before it starts! So I started this year armed with an arsenal of exciting flavored green tea options (I take my New Year's resolutions seriously). Since it was winter, drinking a hot cup of green tea in the morning and at night was a cinch. Then came summer. It took me a couple weeks to transition, but I was sipping iced green tea in no time." - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)

"For example, egcg inhibited lung tumorigenesis in A/J mice induced by NNK and cisplatin (Xu et al., 1992). Theaflavins (a mixture of theaflavin, theaflavin-3-gallate, theaflavin-3'-gallate, and theaflavin-3,3'-digallate) reduced NNK-induced lung tumor multiplicity and volume in A/J mice (Yang et al., 1997a and b). These findings are interesting, given the extremely poor bioavailability of theaflavins, and may suggest that the theaflavins are metabolized to a more-bioavailable active metabolite." - Erich Grotewold, The Science of Flavonoids (Get the book.)

"All treatment groups improved compared to placebo (50 to 75 percent versus 10 percent), but the topical treatment groups improved the most significantly compared to oral alone (75 percent versus 50 to 60 percent) 7° MMHMMMMMMMMMMIMMMNI^^ Green Tea Green tea extract (95% polyphenols, 80% catechins, 55% egcg, 10% caffeine): 300 mg per day orally Green tea suppositories: insert one twice weekly (see treatment plans) Indole-3-Carbinol/Diindolyhnethane (DIM)." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"In addition, egcg had a concurrent effect on two important transcription factors p53 (stabilization of p53) and NF-kB (negative regulation of NF-kB activity), causing a change in the ratio of Bax/Bcl-2 in a manner that favors apoptosis (Hastak et al., 2003). 5.4. Androgen and estrogen receptor It has been found that the androgen receptor (AR) signaling pathway plays important roles in carcinogenesis and cancer progression through regulation of transcription of androgen-responsive genes (Luke and Coffey, 1994)." - Erich Grotewold, The Science of Flavonoids (Get the book.) "PI3K is an important factor in carcinogenesis and an inhibitory effect of flavonoids, egcg, and theaflavins on the activation of PI3K and its downstream effectors may further explain the antitumor promotion action of these flavonoids (Bagli et al, 2004; Harmon and Patel, 2004; Koh et al, 2004; Miyata et al, 2004; Way et al, 2004a and b, 2005). 5.4." - Erich Grotewold, The Science of Flavonoids (Get the book.)

"HCA, CLA, egcg, and Chromium for Weight Loss CLA Cromium Picolinate BACK IN 2004, when I wrote Living the Low Carb Life: Choosing the Diet That's Right for You from Atkins to Zone, I wrote the following sentence in the chapter on supplements: "Memorize this: There are no supplements you can take for weight loss that will cause the pounds to just melt off without you having to do anything at all." - Jonny Bowden, Ph.D., C.N.S., The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why (Get the book.)

"Thus, an extensive review will not be provided here except as these effects relate to neuroprotection, where it appears that the strongest evidence suggests that the primary beneficial properties of egcg may be its antioxidant, anti-inflammatory, and metal chelating abilities. In addition, these catechins appear to enhance prosurvival genes and, as described later for blueberries, act to enhance neuroprotection and reduce stress signaling. This multiplicity of effects appears to provide a significant protection against oxidative and inflammatory stressors." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"Enviga does contain 90mg of egcg and lOOmg of caffeine per 12-ounce can. So drinking three cans per day will provide 270mg of egcg and 300mg of caffeine (about the same amount as in two cups of coffee). The study tested thirty-one people aged between 18 and 35. All of the test subjects were in the normal weight range, so it is not known what effect Enviga may have in overweight and obese individuals. Hypothetically, lets say these results are accurate. In order to burn one pound of fat (3,500 calories), you would need to drink 105 cans of Enviga for 35 days straight." - Michael T. Murray and Michael R. Lyon, Hunger Free Forever: The New Science of Appetite Control (Get the book.)

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