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"They discovered "that sperm from diabetic men have greater levels of dna damage than sperm from men who do not have the disease. They warn that such dna damage might affect a man's fertility" (http://www.sciencedailv.com/releases/2007/05/070503075304.htm). Professor Sheena Lewis, scientific director of the Reproductive Medicine Research Group states "Our study shows increased levels of sperm dna damage in diabetic men. In the context of spontaneous conception, sperm DNA quality has been found to be poorer in couples with a history of miscarriages." - Dr David W Tanton, Ph.D., Antidepressants, Antipsychotics, And Stimulants - Dangerous Drugs on Trial (Get the book.)

"Human study—Carotenoids Can Reduce DNA Damage: in a human study, carotenoids were found to reduce dna damage. Damage to DNA is believed to be the cause of most cancers. Much of this damage is caused by free radicals. Antioxidant nutrients, which include the carotenoids (beta-carotene, alpha-carotene, lycopene, and lutein) can quench free radicals and may reduce the risk of dna damage. in this study, scientists assessed the ability of specific high-carotenoid vegetables to reduce dna damage." - James F. Balch, M.D., The Super Anti-Oxidants: Why They Will Change the Face of Healthcare in the 21st Century (Get the book.)

"Resistant starch prevents colonic dna damage induced by high dietary cooked red meat or casein in rats. Cancer Biol Ther. 2006 Mar;5(3):267-272. Velazquez DVO, Xavier HS, Batista JEM, de Castro-Chaves D. Zea mays L extracts modify glomerular function and potassium urinary excretion in conscious rats. Phytomedicine 2005; 12:363-369. Yuan JM, Stram DO, Arakawa K, Lee HP, Yu MC. Dietary cryptoxanthin and reduced risk of lung cancer: the Singapore Chinese Health Study. Cancer Epidemiol Biomarkers Prev. 2003 Sep;12(9):890-898. Cranberries www.cranberryinstitute.com; http://nccam.nih." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.) "DNA damage in mice. Food Chem Toxicol. 2003 Dec;41(12):1671-1676. Bazzano LA, He J, Ogden LG, Loria CM, Whelton PK. Dietary fiber intake and reduced risk of coronary heart disease in US men and women: the National Health and Nutrition Examination Survey I Epidemiologic Follow-up Study. Arch Intern Med. 2003 Sep 8;163(16):1897-1904. Darmadi-Blackberry et al. Legumes: the most important dietary predictor of survival in older people of different ethnicities. Asia Pac J Clin Nutr. 2004; 13(2):217-220. Mcintosh M, Miller C." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"DNA and can lead to cancer), increasing the number of stomach cells that have dna damage. Second, this bacteria may change the structures of stomach cells, such as cell proteins. This may help cancer cells grow by giving them the structural changes they need to invade and thrive. Scientists are not sure that probiotics can prevent stomach cancer, but their ability to fight H. pylori may help. In Chapter 15,1 will discuss more about the ability of probioitcs to fight H. pylori." - Allison Tannis, Probiotic Rescue: How You can use Probiotics to Fight Cholesterol, Cancer, Superbugs, Digestive Complaints and More (Get the book.) "Studies have found that probiotics prevent dna damage, which is an initiator of cancer. Some epidemiological studies suggest that consumption of fermented dairy products, which are good dietary sources of probiotics, might have protective effects against colon cancer. Thus, it is possible that using probiotics may be a natural way to decrease the risk of colon cancer. Liver Cancer Liver cancer is the sixth most commonly diagnosed cancer in the world." - Allison Tannis, Probiotic Rescue: How You can use Probiotics to Fight Cholesterol, Cancer, Superbugs, Digestive Complaints and More (Get the book.) "DNA damage by carcinogens. In addition, both B. longum and B. animalis can decrease the formation of lesions in the colon that commonly develop into cancer. B. longum may also have anti-tumor activity making it a great probiotic for defending against colorectal cancer. How exactly Bifidobacteria prevents colon (colorectal) cancer bile salts, carcinogens and enzymes that convert pro-carcinogens into carcinogens. support colon health and prevent cancer development in another way. Bifidobacteria is not yet known. Long-term, extensive studies are required and eagerly anticipated." - Allison Tannis, Probiotic Rescue: How You can use Probiotics to Fight Cholesterol, Cancer, Superbugs, Digestive Complaints and More (Get the book.)

"PROSTATE CANCER: Subjects who consumed tomato sauce daily for three weeks before their prostatectomy had a significant decrease in dna damage in prostate tissues and an increase in prostate cancer cell death. A case-control study found a significant inverse association between higher plasma lycopene derived from plant sources such as tomatoes and lower risk of prostate cancer. Tips on Using Tomatoes SELECTION AND STORAGE: • Choose red, plump, heavy tomatoes with smooth skin." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"ROS contribute to cellular aging (Sastre et al, 2000), mutagenesis (Takabe et al, 2001), carcinogenesis (Kawanishi et al, 2001), and coronary heart disease (Khan and Baseer, 2000) possibly through the destabilization of membranes (Takabe et al, 2001), dna damage, and oxidation of low-density lipoprotein (LDL). Many in vitro studies have demonstrated the potent peroxyl radical scavenging abilities of flavonoids, which contribute to inhibiting lipid peroxidation and oxidation of LDL (Castelluccio et al, 1995; Salah et al, 1995)." - Erich Grotewold, The Science of Flavonoids (Get the book.) "Mechanism of guanine-specific dna damage by oxidative stress and its role in carcinogenesis and aging, Mutat Res, 488: 65-76. Kelm, M. A., Hammerstone, J. F., and Schmitz, H. H., 2005, Identification and quantitation of flavanols and proanthocyanidins in foods: how good are the datas? Clin Dev Immunol, 12: 35-41. Khan, M. A., and Baseer, A., 2000, Increased malondialdehyde levels in coronary heart disease, J Pak Med Assoc, 50: 261-264. Khan, W. A., Wang, Z. Y„ Athar, M., Bickers, D. R., and Mukhtar, H." - Erich Grotewold, The Science of Flavonoids (Get the book.) "Protection from UV-B-induced dna damage by flavonoids, Plant Mol Biol 26: 771-774. Kroon, A. R., 2004, Thesis: Transcriptional regulation of the anthocyanin pathway in Petunia hybrida, Vrije Universiteit, Amsterdam. Kubo, H., Peeters, A. J., Aarts, M. G., Pereira, A., and Koornneef, M„ 1999, ANTHOCYANINLESS2, a homeobox gene affecting anthocyanin distribution and root development in Arabidopsis, Plant Cell 11: 1217-1226. Lee, M. M., and Schiefelbein, J., 1999, WEREWOLF, a MYB-related protein in Arabidopsis, is a position-dependent regulator of epidermal cell patterning, Cell 99: 473-483." - Erich Grotewold, The Science of Flavonoids (Get the book.)

"Human study—Carotenoids Can Reduce DNA Damage: in a human study, carotenoids were found to reduce dna damage. Damage to DNA is believed to be the cause of most cancers. Much of this damage is caused by free radicals. Antioxidant nutrients, which include the carotenoids (beta-carotene, alpha-carotene, lycopene, and lutein) can quench free radicals and may reduce the risk of dna damage. in this study, scientists assessed the ability of specific high-carotenoid vegetables to reduce dna damage." - James F. Balch, M.D., The Super Anti-Oxidants: Why They Will Change the Face of Healthcare in the 21st Century (Get the book.)

"Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to dna damage, J Biol Chem, 275: 322-327. Kirk, E. A., Sutherland, P., Wang, S. A., Chait, A., and LeBoeuf, R. C, 1998, Dietary isoflavones reduce plasma cholesterol and atherosclerosis in C57BL/6 mice but not LDL receptor-deficient mice, J Nutr, 128: 954-959. Ko, C. H., Shen, S. C, Lee, T. J., and Chen, Y. C, 2005, Myricetin inhibits matrix metalloproteinase-2 protein expression and enzyme activity in colorectal carcinoma cells, Mol Cancer Ther, 4: 281-290. Koh, S. H., Kim, S. H., Kwon, H., Kim, J. G." - Erich Grotewold, The Science of Flavonoids (Get the book.)

"Kiwifruit protects against oxidative dna damage in human cells and in vitro. Nutr Cancer. 2001;( 1): 148—153. Duttaroy AK, Jorgensen A. Effects of kiwi fruit consumption on platelet aggregation and plasma lipids in healthy human volunteers. Platelets. 2004 Aug;15(5):287-292. Kopsell D, Kopsell D, Curran-Celentano J. Carotenoid variability among kale and spinach cultivars. Hortscience. 2004;(2):34. Motohashi N et al. Cancer prevention and therapy with kiwifruit in Chinese folklore medicine: a study of kiwifruit extracts. / Ethnopharmacol. 2002 Aug;81(3):357-364. Rinzler CA." - David W. Grotto, RD, LDN, 101 Foods That Could Save Your Life! (Get the book.)

"The combination of oral vitamin C and vitamin E (one gram of each), adminisrered to male patients with dna damage who had previously failed fertility treatments for two months, was shown to decrease DNA-fragmented sperm, and a second fertility treatment led to improvement of clinical pregnancy and implantation rates.62 Vitamin C 500-3,000 mg 3 times daily Vitamin E 500-1,000 IU per day L-Carnitine. The amino acid L-carnitine is essential for normal functioning of sperm." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.) "Vitamin C and other antioxidants can decrease sperm dna damage that can interfere with fertility.59 Vitamin C deficiency has been linked with significant decreases in sperm count, motility, and vitality and with an increase in morphologically abnormal sperm.60 Vitamin E and selenium have been shown to reduce lipid peroxidation and, therefore, improve sperm quality. One study looked at men who had normal sperm counts, but low rates of fertilization during in vitro fertilization treatments." - Tori Hudson, N.D., Women's Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness (Get the book.)

"Oxidative dna damage levels in rats fed low-fat, high-fat, or calorie-restricted diets. Toxicol. Appl. Pharmacol. 115, 156-160. 67. Djuric, Z., Heilbrun, L. K., Reading, B. A., Boomer, A., Valeriote, F. A., and Martino, S. (1991). Effects of a low-fat diet on levels of oxidative damage to DNA in human peripheral nucleated blood cells. J. Natl. Cancer Inst. 83, 766-769. 68. Kato, I., Ren, J., Heilbrun, L. K., and Djuric, Z. (2006). Intra-and inter-individual variability in measurements of biomarkers for oxidative damage in vivo: Nutrition and Breast Health Study. Biomarkers 11, 143-152. 69." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.) "The 8-hydroxylation of the guanine base is a frequent type of oxidative dna damage, and 80HdG is subsequently excreted without further metabolism in the urine after repair in vivo by exonucleases. In previous studies, certain demographic factors and physiological characteristics such as gender and body mass [58] have been observed to influence urinary 80HdG concentration, so these factors may need to be considered in interpretation." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.) "Determination of urinary 8-hydroxydeoxy guanosine by automated coupled-column high performance liquid chromatography: a powerful technique for assaying in vivo oxidative dna damage in cancer patients. Eur. J. Cancer 31A, 934-940. 60. Thompson, H. J., Heimendinger, J., Haegele, A., Sedlacek, S. M., Gillette, C, O'Neill, C, Wolfe, P., and Conry, C. (1999). Effect of increased vegetable and fruit consumption on markers of oxidative cellular damage. Carcinogenesis 20, 2261-2266. 61. Johansson, G, Holmen, A., Persson, L., Hogstedt, R., Wassen, C, Ottova, L., and Gustafsson, J. A. (1992)." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.) "Muscarinic receptor activation protects cells from apoptotic effects of dna damage, oxidative stress and mitochondrial inhibition. J. Biol. Chem. 278, 11086-11093. 274. Huidobro, A., Blanco, P., Villalba, M, Gomez-Puertas, P., Villa, A., Pereira, R., Bogonez, E., Martinez-Serrano, A., Aparicio, J. J., and Satrustegui, J. (1993.). Age-related changes in calcium homeostatic mechanisms in synapto-somes in relation with working memory deficiency. Neurobiol. Aging 14, 479-486. 275. Nyakas, C, Oosterink, B. J., Keijser, J., Felszeghy, K., de Jong, G. I., Korf, J., and Luiten, D. G. (1997)." - Ann M. Coulston and Carol J. Boushey, Nutrition in the Prevention and Treatment of Disease (Get the book.)

"People who have adequate folic acid intake, however, may have a better capacity to repair dna damage caused by acetaldehyde." As long as you eat plenty of fruits and vegetables, beans and peas, and fortified breads and cereals, you should meet the recommended daily allowance for folic acid (400 micrograms). Vitamin D. This powerful vitamin isn't just about boosting bones! There's so much more to vitamin D than enhancing calcium absorption; its anticancer benefit is just one other possibility." - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.) "Similar to the dna damage associated with radiation, free-radical damage has been associated with cancer. POLYPHENOL FAMILY Polyphenols are the mother of all phytochemical families, containing a whopping 2,000-plus compounds. Polyphenols give many fruits and vegetables their blue, red-blue, or violet colors. This amazing family is basically divided into two subgroups, phenolic acids and flavonoids." - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.) "Whole grains may accomplish this by blocking dna damage, suppressing the growth of cancer cells, providing antioxidant protection, and preventing the formation of carcinogens. The particular components of whole grains that offer such protection include fiber, antioxidants including vitamins (like vitamin E) and minerals (like selenium), and various phytochemicals. Ready to start adding more whole grains to your life? Just say yes." - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.) "Weissinger suspects that the carotenoids (or other compounds linked to them by virtue of being in the same foods) could be protecting T cells from dna damage, a known means to developing this form of cancer. Carotenoids seem to protect DNA, so this makes sense. "If the DNA in T cells is damaged, faulty programming can be passed on and a mutated line of cells created, resulting in a lymphoma," explains Weissinger. Want to know what fruits and vegetables are rich in the carotenes/carotenoids besides carrots and sweet potatoes? Check out "Food Sources of Standout Carotenoids" on page 84." - Elaine Magee, Food Synergy: Unleash Hundreds of Powerful Healing Food Combinations to Fight Disease and Live Well (Get the book.)

"In a 2002 randomized controlled trial, researchers assessed the effect of 200 g of tomato sauce daily (containing 30 mg of lycopene) on dna damage in men with prostate cancer. There were many notable benefits from the tomato sauce that yielded statistical significance, some of which included a 17.5% decrease in mean prostate specific antigen (PSA) levels, and a reduction in dna damage in both leukocyte (white blood cell) and prostate tissue. The results of these studies indicate that lycopene or lycopene-containing foods can exert potent anticancer effects among men with prostate cancer." - Abram Hoffer, PhD, MD, FRCP(C) and Dr. Jonathan Prousjy, DPHE, DSC, ND, FRSH, Naturopathic Nutrition: A Guide to Nutrient-rich Food & Nutritional Supplements for Optimum Health (Get the book.)

"Could any of the chemicals used in popular fertility treatments be causing dna damage? These chemicals have to be doing something to the cells, but what exactly? What are the long-term physical and developmental effects of fertility treatments? I'm not saying fertility treatments are bad or good; I'm just saying that we need to start asking these and other questions. We also need to start demanding answers. We need to be absolutely certain that the preservatives used in these procedures are as safe as possible—we need to demand proof." - Deirdre Imus, Growing Up Green: Baby and Child Care: Volume 2 in the Bestselling Green This! Series (Green This!) (Get the book.)

"Researchers in the Netherlands investigated the effect of a diet high in Brussels sprouts on dna damage. They compared two groups of healthy male volunteers. Five men ate a diet that included 300 grams (about 10 ounces) of cooked Brussels sprouts daily, while the other five men ate a diet free of cruciferous vegetables. After three weeks, the group that ate Brussels sprouts had a 28 percent decrease in measured dna damage. Reduced dna damage may translate to a reduced risk of cancer since mutations in DNA are what lead to the development of cancerous cells." - Michael Murray, N.D. and Joseph Pizzorno, N.D., The Encyclopedia of Healing Foods (Get the book.)

"Green tea seems to be able to almost totally prevent cancer causing dna damage in smokers—a possible explanation as to why the Japanese, who are among the world's heaviest smokers, have such a low incidence of lung cancer. And finally, green tea has great benefits for the brain as well, serving as an effective MAO inhibitot, protecting against btain-cell death from glucose oxidase, overproduction of nitric oxide, and lowering the amount of free iron reaching the brain (a bad thing)." - Jon Barron, Lessons from The Miracle Doctors: A Step-by-Step Guide to Optimum Health and Relief from Catastrophic Illness (Get the book.)

"They warn that such dna damage might affect a man's fertility" (http://www.sciencedailv.com/releases/2007/05/070503075304.htm). Professor Sheena Lewis, scientific director of the Reproductive Medicine Research Group states "Our study shows increased levels of sperm dna damage in diabetic men. In the context of spontaneous conception, sperm DNA quality has been found to be poorer in couples with a history of miscarriages." They warn that "The incidence of type 1 and type 2 diabetes is increasing rapidly worldwide," and it's easy to see why." - Dr David W Tanton, Ph.D., Antidepressants, Antipsychotics, And Stimulants - Dangerous Drugs on Trial (Get the book.)

"The bottom line is that everyone should be on a supplement to prevent homocysteine damage to the cardiovascular system, cancer, dna damage, and deterioration of the btain. S-adenosylmethionine, also known as SAMe is a popular alternative. But a less expensive choice is to purchase at any discount health store a formula that contains 500 mg of trimethylglycine, 50 mg of B-6, 800 meg of folic acid, 500 meg of B-12 (best in the form of methylcobalamine, if you can find it). Foods Certain foods are high in antioxidants and should be a regular part of the diet." - Jon Barron, Lessons from The Miracle Doctors: A Step-by-Step Guide to Optimum Health and Relief from Catastrophic Illness (Get the book.)

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