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Quotes about Crestor from the world's top natural health / natural living authors

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"The crestor Charity Challenge, which AstraZeneca was paying to sponsor at thirty-five professional golf tournaments around the country in 2005, sent an implicit message that crestor was better and safer than any of the other cholesterol-lowering pills. This was not the case. In fact, in all the pharmaceutical marketing on the golf course that day, there was not one mention of the risks of these pills, which were not insignificant. Studies had shown that crestor appeared to be more toxic to the muscles than other cholesterol drugs." - Melody Petersen, Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs (Get the book.)

"Because of concerns about crestor, in 2003 a consumer group urged the FDA to withhold approval of Crestor; however, the FDA still approved it. Since that time there have been 65 cases of rhabdomyolysis with crestor reported to the FDA, some of them fatal. Although death from statins is rare, given the large number of people who take these drugs, muscle pain (myalgia) in the absence of changes in laboratory values like CK are more common, affecting 2% to 3% of patients. Studies have shown that myalgia can be associated with changes in muscle tissue." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"One is whether the same benefits could be achieved using other statins instead of crestor because of concerns about its safety. The consumer advocacy group Public Citizen has petitioned the US Food and Drug Administration (FDA) to take crestor off the market. But the agency concluded that the available evidence about Crestor's safety does not warrant its withdrawal from the market. Public Citizen isn't likely to change its stance, despite this new research. "The study is a bit less impressive than perhaps is put forth," says Dr." - Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.)

"Government and company records show that from 2001 to 2003, he accepted about $114,000 in consulting fees from four companies making or developing cholesterol medications, including $31,000 from the maker of crestor (AstraZeneca) " In the August 21, 2003 issue of the American Journal of Cardiology, Brewer wrote that Crestor's "benefit-risk profile ... appears to be very favorable". He assured doctors there was no basis for worry about rhabdomyolysis, claiming that, "No cases of rhabdomyolysis occurred in patients receiving [Crestor] at 10 to 40" milligrams." - Anthony Colpo, The Great Cholesterol Con: Why Everything You've been Told About Cholesterol, Diet and Heart Disease is Wrong (Get the book.)

"Physicians must tell their patients the truth" about crestor, the influential British medical journal The Lancet had stated in 2003. Compared with its competitors, the journal said, crestor has "an inferior evidence base supporting its safe use." The erectile enhancement drug Cialis, on the other hand, could cause dangerous drops in blood pressure. A small number of patients taking it had mysteriously gone blind. By marketing on the golf course, the drugmakers avoided federal rules that required them to tell consumers of the dangers." - Melody Petersen, Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs (Get the book.) "Drugmaker AstraZeneca had created the contest to promote its new cholesterol pill, crestor. The name of the contest was brilliant. The crestor Charity Challenge evoked recollections of the Pepsi Challenge, a promotional gimmick that the soda pop manufacturer had used repeatedly in ads to create the impression that cola drinkers preferred the taste of its product to that of Coke." - Melody Petersen, Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs (Get the book.)

"Statins sell under a variety of brand names: Mevacor, Lipitor, Prava-chol, Zocor, Lescol, and crestor. Technically, they are HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitors, meaning they reduce the action of the principal enzyme in the liver that produces cholesterol. The targeted medical effect is to decrease LDL cholesterol. We use statins extensively but selectively in our practices. They have definite therapeutic value, but they also have definite downsides. They are too often inappropriately prescribed by physicians solely preoccupied with cholesterol." - Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)

"For example, in August 2003, the FDA approved a statin drug called crestor (rosuvastatin calcium). But because high amounts of it can cause muscle destruction that may lead to kidney damage (and failure), it can be prescribed only in small doses and requires doctors to monitor a patient's muscle enzymes and kidney and liver functions every three months. (For more about toxins and pharmaceutical drugs, see Appendix C.) A connection has also been found between exposure to cadmium and lead and an increase in cholesterol levels." - Brenda Watson and Leonard Smith, The Detox Strategy: Vibrant Health in 5 Easy Steps (Get the book.)

"Compared with its competitors, the journal said, crestor has "an inferior evidence base supporting its safe use." The erectile enhancement drug Cialis, on the other hand, could cause dangerous drops in blood pressure. A small number of patients taking it had mysteriously gone blind. By marketing on the golf course, the drugmakers avoided federal rules that required them to tell consumers of the dangers. They also happened to be taking a page from the marketing manuals of R. J. Reynolds and other tobacco companies." - Melody Petersen, Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs (Get the book.)

"In this study, ultrasound measurements were made before and two years after the start of crestor treatment. The researchers reported a modest 1 percent reduction of each patient's major blockage. That may not sound like much, but mathematically plaque needs only to shrink a miniscule amount-just a small improvement to the diameter of a blood vessel—to significantly enhance blood flow." - Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)

"Graham, testified that other drugs still on the mar- ket were unsafe, including Accutane and Arava (for the treatment of rheumatoid arthritis) that cause "an unacceptably high risk of acute liver failure and death;"148 crestor (a cholesterol lowering drug) that causes myopathy and rhabdomyalysis; Meridia (a weight loss drug) that causes heart arrhythmias; and Serevent (an asthma drug) that causes a three-fold increase in the risk of death from asthma." - Jonathan W. Emord, The Rise of Tyranny (Get the book.)

"Since that time there have been 65 cases of rhabdomyolysis with crestor reported to the FDA, some of them fatal. Although death from statins is rare, given the large number of people who take these drugs, muscle pain (myalgia) in the absence of changes in laboratory values like CK are more common, affecting 2% to 3% of patients. Studies have shown that myalgia can be associated with changes in muscle tissue. All of the statins can cause problems with memory and joint pains. In fact, on Web sites like askthepatient.com statins are one of the most negatively rated drugs around." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"AstraZeneca, the maker of crestor, has chosen to fight such charges, investing millions in a public relations and ad campaign to establish crestor as the next blockbuster statin. It is too soon to tell what will happen. There is also the concern that wholesale adoption of statins essentially causes people to indulge in imprudent lifestyles — a kind of "I'm on Lipitor so give me my Big Mac and shut up" mentality." - Greg Critser, Generation Rx: How Prescription Drugs are Altering American Lives, Minds, and Bodies (Get the book.)

"The consumer advocacy group Public Citizen has petitioned the US Food and Drug Administration (FDA) to take crestor off the market. But the agency concluded that the available evidence about Crestor's safety does not warrant its withdrawal from the market. Public Citizen isn't likely to change its stance, despite this new research. "The study is a bit less impressive than perhaps is put forth," says Dr. Peter Lurie, deputy director of Public Citizen's Health Research Group. "Many patients were lost to follow-up." - Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.)

"The statins like crestor that have greater potency are offset by more side effects. I recommend taking a statin that you can buy in generic form, like atorvastatin (generic Lipitor), since it costs much less." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"This very same crestor has been under fire by the consumer group Public Citizen, which contends that this drug has "unique risks" and should not be prescribed, especially at the dose (40 mg a day] used in the study unless smaller doses and other drugs fail to help. The Food and Drug Administration in 2005 required a warning on its label because of potentially serious kidney and musculoskeletal problems." - Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)

"FDA records also show that it received seventy-eight reports of rhabdomyolysis among patients taking crestor during its first year on the market. Two of those patients died. AstraZeneca sales representatives have routinely provided copies of Brewer's journal article about crestor to doctors nationwide, the LA Times reported(8). Brewer was hardly the only NIH employee writing recommendations for the public with one hand and receiving drug company money with the other." - Anthony Colpo, The Great Cholesterol Con: Why Everything You've been Told About Cholesterol, Diet and Heart Disease is Wrong (Get the book.) "But eight cases of rhabdomyolysis were reported during clinical trials of crestor. One case involved a patient who took the drug in ten-milligram doses, according to records filed with the Food and Drug Administration and reviewed by the LA Times under the Freedom of Information Act. FDA records also show that it received seventy-eight reports of rhabdomyolysis among patients taking crestor during its first year on the market. Two of those patients died." - Anthony Colpo, The Great Cholesterol Con: Why Everything You've been Told About Cholesterol, Diet and Heart Disease is Wrong (Get the book.)

"We have identified three likely incremental winners in the 2006 statin market—AstraZeneca, Schering-Plough, and an undisclosed marketing partner for crestor." The newsletter continues: "there are not likely to be any outright losers." No mention is made of the patients and the doctors who are more concerned about their own and others' health and well-being than about pharmaceutical company profits. We are the losers." - John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.) "Crestor, was approved by the FDA in August 2003. WHY DOES CHOLESTEROL GET SO MUCH ATTENTION? It is important to keep in mind that cholesterol is not a health risk in and of itself. In fact, cholesterol is vital to many of the body's essential functions. For example, cholesterol is the most common organic molecule in the brain (this could explain why statins have a small but statistically significant negative effect on cognitive function)." - John Abramson, Overdosed America: The Broken Promise of American Medicine (P.S.) (Get the book.)

"Graham identified five widely prescribed drugs still on the market that are particularly dangerous, including Accutane, Bextra, crestor, Me-ridia, and Serevent. (In 2005 Bextra was taken off the market.) While it's true that many drugs help people live longer and better lives, myriad others may be harmful in ways you're unaware of. Dr. Graham's testimony provided the public a fleeting glimpse of the knowledge that is normally hidden from view or frustratingly difficult for the average person to access." - J. Douglas Bremner, Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health (Get the book.)

"In this new study, headed by physicians at the Cleveland Clinic and funded by crestor maker AstraZeneca PLC, two-thirds of the 349 study participants were reported to have had regression of plaque buildups. For the first time, a drug showed regression of plaque. The researchers based their finding on intracoronary ultrasound, a technique in which a tiny camera is inserted into the coronary artery. With this technology one can literally scan the inside of the artery and see the plaque load inside the vessel and determine whether there is buildup or regression." - Stephen Sinatra, M.D. and James C., M.D. Roberts, Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late (Get the book.)

"He alleged GlaxoSmithKline's asthma drug Serevent; AstraZeneca's statin, Crestor; Pfizer's latest Cox-2 inhibitor, Bextra; Roche's acne drug, Accutane; and Abbott Laboratories' slimming drug Meridia (Reductil in the UK), as all having had the same whitewash treatment to present their best side, rather than the warts-and-all version people need if they are to live in what can be considered a civilized society. The stock market responded to Graham's remarks, with the share prices of all five companies concerned falling, some quite significantly." - Jacky Law, Big Pharma: Exposing the Global Healthcare Agenda (Get the book.)

"A recent advertisement for crestor, a new statin yet to fulfill its original sales ambition, is framed, in full color, by a cornucopia of fresh vegetables.) Does that mean many of the "wrong" people are taking statins? Perhaps. But there is also evidence that not enough of the "right" people are on them, particularly the poor. Yet members of the statin-ACE tribe do share the winking notion that they have put fate on hold. Daily pills have become a reminder of risk, consciously reduced." - Greg Critser, Generation Rx: How Prescription Drugs are Altering American Lives, Minds, and Bodies (Get the book.)

"Continued from the article previously referred to, in the New Yorl< Times: AstraZeneca, Crestor's maimer, says that the drug is safe and dismisses the accusations made by Public Citizen as groundless. Golomb said she has been documenting cases of adverse events associated with statin use. Golomb said, the problems resolved after the patients stopped the statin and came back if they went back on the drug or took another statin. One participant in Golomb's study, Jane Brunzie, 66, of Vista, Calif, said she began having frequent "senior moments" while on a regimen of 30 milligrams of Lipitor." - Dr. David W. Tanton; Ph.D., A Drug-Free Approach To Healthcare, Revised Edition (Get the book.)

"But the agency concluded that the available evidence about Crestor's safety does not warrant its withdrawal from the market. Public Citizen isn't likely to change its stance, despite this new research. "The study is a bit less impressive than perhaps is put forth," says Dr. Peter Lurie, deputy director of Public Citizen's Health Research Group. "Many patients were lost to follow-up. And there is no comparison group, so we have no way of knowing if some other drug might not have accomplished exactly the same thing," he says. "It leaves many questions unanswered." - Bottom Line Health, Bottom Line's Health Breakthroughs 2007 (Get the book.)

"AstraZeneca sales representatives have routinely provided copies of Brewer's journal article about crestor to doctors nationwide, the LA Times reported(8). Brewer was hardly the only NIH employee writing recommendations for the public with one hand and receiving drug company money with the other. The LA Times revealed in late 2003 that hundreds of NIH employees had been accepting consulting fees from biotech and pharmaceutical companies at least since November 1995, when then-NIH Director Harold E. Varmus relaxed the Institute's conflict-of-interest rules. Current Director Dr. Elias A." - Anthony Colpo, The Great Cholesterol Con: Why Everything You've been Told About Cholesterol, Diet and Heart Disease is Wrong (Get the book.)

"For example, widely prescribed statin drugs, such as crestor and Lipitor, block the activity of an enzyme that creates cholesterol in the body—but this action depletes the body of a substance called coenzyme Q10, which is vital for heart health. Enzyme A protein that accelerates the rate of chemical reactions, without being damaged or changed by the reactions. 5. Increased loss of nutrients through the urinary system. Any drug that causes an increase in urination can drain the body's levels of water-soluble nutrients, including B vitamins and minerals such as magnesium and potassium." - Hyla Cass, M.D., Supplement Your Prescription: What Your Doctor Doesn't Know About Nutrition (Get the book.)

"A study conducted by cardiologists at the Cleveland Clinic reported that high-dose crestor treatment lowered LDL cholesterol 52 to 60 percent and reduced plaque buildup in coronary arteries by 9 percent.536 Anyone at moderately high risk for a heart attack (but without prior history of heart disease) is advised to get his or her LDL cholesterol below 100, and those at the highest risk are supposed to get their level below 70 mg/dl. Some cardiologists want the LDL level to be even lower. Such numbers can be achieved only by taking cholesterol-lowering drugs." - Joe Graedon, M.S. and Teresa Graedon, Ph.D., Best Choices From the People's Pharmacy (Get the book.)

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